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51. 发明授权

US07693560B2 Dual electrode system for a continuous analyte sensor 有权
公开(公告)号：US07693560B2
公开(公告)日：2010-04-06
申请号：US11692154
申请日：2007-03-27
申请人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
发明人： Peter C. Simpson , James H. Brauker , Paul V. Goode , Apurv U. Kamath , James R. Petisce , Kum Ming Woo , Melissa A. Nicholas , Robert J. Boock , Monica A. Rixman , John Burd , Rathburn K. Rhodes , Mark A. Tapsak
IPC分类号： A61B5/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.

52. 发明申请

US20080119703A1 Analyte sensor 审中-公开
标题翻译：分析物传感器
公开(公告)号：US20080119703A1
公开(公告)日：2008-05-22
申请号：US11543396
申请日：2006-10-04
申请人： Mark Brister , Sean Saint , Vance Swanson , James R. Petisce
发明人： Mark Brister , Sean Saint , Vance Swanson , James R. Petisce
IPC分类号： A61B5/05 , A61B5/00
CPC分类号： A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/412 , A61B5/6848 , A61B5/6849 , A61B2560/0223 , A61M5/14 , A61M5/16804 , A61M5/1723 , A61M2230/201
摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into a host's peripheral vein or artery.
摘要翻译：提供了用于宿主血管系统的连续分析物测量的系统和方法。在一些实施例中，连续葡萄糖测量系统包括血管通路装置，传感器和传感器电子装置，所述系统被配置为插入宿主的外周静脉或动脉。

53. 发明申请

US20080086044A1 ANALYTE SENSOR 有权
公开(公告)号：US20080086044A1
公开(公告)日：2008-04-10
申请号：US11691424
申请日：2007-03-26
申请人： Mark Brister , Mark Shults , Sean Saint , James R. Petisce , David K. Wong , Kum Ming Woo
发明人： Mark Brister , Mark Shults , Sean Saint , James R. Petisce , David K. Wong , Kum Ming Woo
IPC分类号： A61B5/157
CPC分类号： A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/412 , A61B5/6848 , A61B5/6849 , A61B2560/0223 , A61M5/14 , A61M5/16804 , A61M5/1723 , A61M2230/201
摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

54. 发明授权

US06317553B1 Coated fiber strands having one or more heterogeneous regions and methods of making the same 有权
标题翻译：具有一个或多个异质区域的涂覆纤维线束及其制造方法
公开(公告)号：US06317553B1
公开(公告)日：2001-11-13
申请号：US09307306
申请日：1999-05-07
申请人： Daniel Harper, Jr. , John M. Turnipseed , Carl R. Taylor , Priya L. Tabaddor , James R. Petisce
发明人： Daniel Harper, Jr. , John M. Turnipseed , Carl R. Taylor , Priya L. Tabaddor , James R. Petisce
IPC分类号： G02B602
CPC分类号： C03C25/50 , C03C25/1065 , C03C25/475
摘要： A coated fiber strand includes one or more coating layers located directly or indirectly on the strand and at least one heterogeneous region present in or on one or more of the coating layer(s). The heterogeneous region(s) preferably comprises a material useful for coding of the fiber. One particularly preferred embodiment relates to an optical fiber having a primary coating layer and a secondary coating layer where the heterogeneous region(s) defines one or more colored stripes in or on the secondary coating layer. A method for forming a coated fiber, such as an optical fiber, includes introducing at least one coating layer onto a fiber strand such that one or more coating layers directly or indirectly cover at least a portion of the surface of the strand. The method further includes introducing at least one heterogeneous region into or onto a coating layer(s). The fiber can then be treated, e.g., cured so as to provide a desired product. By this method, a desired functionality, e.g., coding, can be introduced onto a fiber without adversely effecting subsequent processing steps, e.g., curing of the coating layer(s).
摘要翻译：涂覆的纤维股线包括直接或间接地位于股线上的一个或多个涂层，以及存在于一个或多个涂层中或之上的至少一个非均匀区域。多相区域优选地包含可用于编码纤维的材料。一个特别优选的实施方案涉及具有初级涂层和次级涂层的光纤，其中非均匀区域在二次涂层中或其上限定一个或多个着色条纹。用于形成诸如光纤的涂覆纤维的方法包括将至少一个涂层引入到纤维束上，使得一个或多个涂层直接或间接覆盖该链的表面的至少一部分。该方法还包括将至少一个非均匀区域引入到涂层中或涂覆层上。然后可以处理纤维，例如固化，以便提供所需的产品。通过该方法，可以将期望的功能性（例如编码）引入到纤维上，而不会不利地影响随后的加工步骤，例如固化涂层。

55. 发明授权

US06169126A Radiation-curable optical fiber primary coating system 失效
标题翻译：可辐射固化光纤一次涂层系统
公开(公告)号：US06169126A
公开(公告)日：2001-01-02
申请号：US09353659
申请日：1999-07-15
申请人： David M. Szum , Chander P. Chawla , James R. Petisce , George Pasternack , Timothy E. Bishop , Paul E. Snowwhite , Edward P. Zahora
发明人： David M. Szum , Chander P. Chawla , James R. Petisce , George Pasternack , Timothy E. Bishop , Paul E. Snowwhite , Edward P. Zahora
IPC分类号： C08F248
CPC分类号： C03C25/1065 , Y10T428/2938 , Y10T428/2942 , Y10T428/2947 , Y10T428/2962 , Y10T428/2967
摘要： Optical fiber primary coating systems are disclosed having excellent ribbon stripping and adhesion behavior. The coatings are radiation-curable. The excellent stripping and adhesion behavior can be inner primary coating composition having a slip enhancing component and a high modulus outer primary coating composition. Combination of means can be employed. Stripping behavior can be measured by crack propagation and fiber friction measurements.
摘要翻译：公开了具有优异的带剥离和粘合行为的光纤一次涂覆系统。涂层是可辐射固化的。良好的剥离和粘附性能可以是具有滑爽增强组分和高模量外部初级涂料组合物的内部初级涂料组合物。可以组合手段。剥离行为可以通过裂纹扩展和纤维摩擦测量来测量。

56. 发明授权

US5373578A Strippable coating for optical fiber 失效
标题翻译：光纤剥离涂层
公开(公告)号：US5373578A
公开(公告)日：1994-12-13
申请号：US170885
申请日：1993-12-21
申请人： Theodore L. Parker , James R. Petisce , Lloyd Shepherd , Carl R. Taylor
发明人： Theodore L. Parker , James R. Petisce , Lloyd Shepherd , Carl R. Taylor
IPC分类号： C03C25/10 , C03C25/24 , G02B6/245 , G02B6/44 , G02B6/22
CPC分类号： G02B6/4403 , C03C25/106 , C03C25/1065 , G02B6/245 , G02B6/443 , Y10T428/2933 , Y10T428/2964
摘要： A coating system for individual glass fibers of a lightwave communications system has improved strippability, particularly in situations where a group of such fibers are arrayed together in what is known as a ribbon. A preferred embodiment includes two layers (primary and secondary) of polymeric materials surrounding the glass fiber. The primary layer comprises an oligomer (50-80% by weight), a diluent (15-40% by weight), and additives (5-35% by weight). The oligomer comprises polyol "A," diisocyanate "B," and a hydroxy-terminated alkyl acrylate "C" having the structure C-B-A-B-C. At least one of the additives contains a non-crosslinked hydrocarbon component (1-20% by weight) having a structure R.sub.1 --(R).sub.n --R.sub.2 ; where R.sub.1, R.sub.2 comprises an alkyl group or an OH group, and R is a combination of C, H or C, H, O. In an alternative embodiment, the need for a diluent is substantially eliminated by using an oligomer having the structure E-D-E where "D" represents a carboxy-terminated polyol, and "E" represents a glycidyl acrylate.
摘要翻译：用于光波通信系统的单个玻璃纤维的涂覆系统具有改善的剥离性，特别是在将一组这种纤维以所谓的带状排列在一起的情况下。优选的实施方案包括围绕玻璃纤维的聚合材料的两层（初级和次级）。主层包含低聚物（50-80重量％），稀释剂（15-40重量％）和添加剂（5-35重量％）。低聚物包含多元醇“A”，二异氰酸酯“B”和具有结构C-B-A-B-C的羟基封端的丙烯酸烷基酯“C”。至少一种添加剂含有具有结构R1-（R）n-R2的非交联烃组分（1-20重量％）; 其中R1，R2包含烷基或OH基团，R是C，H或C，H，O的组合。在一个替代实施方案中，通过使用具有结构EDE的低聚物，基本上消除了稀释剂的需要其中“D”表示羧基封端的多元醇，“E”表示丙烯酸缩水甘油酯。

57. 发明授权

US5147433A Methods of making coated optical fiber 失效
标题翻译：制作涂层光纤的方法
公开(公告)号：US5147433A
公开(公告)日：1992-09-15
申请号：US780451
申请日：1991-10-22
申请人： James R. Petisce
发明人： James R. Petisce
IPC分类号： C03C25/10 , G02B6/44
CPC分类号： C03C25/1065 , G02B6/443
摘要： A drawn optical fiber (21) is provided with inner and outer layers (42,44) of coating material to protect the optical fiber during handling and use. The coating materials are such that they are characterized by being curable upon exposure to different portions of the light spectrum. In a preferred embodiment, the coating material of the inner layer includes a photoinitiator which absorbs light in the visible portion of the light spectrum whereas the outer coating material of the outer layer includes a photoinitiator which absorbs light in the ultraviolet light portion of the light spectrum.
摘要翻译：拉制的光纤（21）设置有涂层材料的内层和外层（42,44），以在处理和使用期间保护光纤。涂层材料的特征在于其可以在暴露于光谱的不同部分时固化。在优选的实施方案中，内层的涂层材料包括吸收光谱可见部分中的光的光引发剂，而外层的外涂层包括吸收光谱的紫外光部分中的光的光引发剂。

58. 发明授权

US09610031B2 Transcutaneous analyte sensor 有权
公开(公告)号：US09610031B2
公开(公告)日：2017-04-04
申请号：US13086160
申请日：2011-04-13
申请人： Mark Brister , Paul V. Neale , James R. Petisce , James Patrick Thrower , Sean Saint , John Nolting
发明人： Mark Brister , Paul V. Neale , James R. Petisce , James Patrick Thrower , Sean Saint , John Nolting
IPC分类号： A61B5/1473 , A61B5/1495 , A61B5/1486 , A61M5/14 , A61B5/05 , A61B5/145 , A61B5/00 , A61B5/15 , A61B17/34 , A61M5/172 , A61M5/158 , A61M5/142
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0004 , A61B5/05 , A61B5/14 , A61B5/1411 , A61B5/145 , A61B5/14503 , A61B5/14507 , A61B5/14514 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/6801 , A61B5/6832 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/72 , A61B17/3468 , A61B2017/3492 , A61B2560/0223 , A61B2560/045 , A61M5/14 , A61M5/14244 , A61M5/1723 , A61M2005/1585 , G06F19/00 , Y02A90/26
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host including a sensor; a mounting unit for placement on the skin of a host; a sensor introducer coupled to the sensor and to the mounting unit, the sensor introducer configured to transcutaneously introduce a portion of the sensor through a skin of the host to a first position relative to the mounting unit, and a data processing unit configured to couple to the mounting unit, the data processing unit displacing the sensor to a second position relative to the mounting unit upon coupling to the mounting unit.

59. 发明授权

US08911369B2 Dual electrode system for a continuous analyte sensor 有权
标题翻译：用于连续分析物传感器的双电极系统
公开(公告)号：US08911369B2
公开(公告)日：2014-12-16
申请号：US12335403
申请日：2008-12-15
申请人： Mark Brister , James R. Petisce , Peter Simpson
发明人： Mark Brister , James R. Petisce , Peter Simpson
IPC分类号： A61B5/05 , A61B5/145 , A61B5/1495 , A61B5/1486 , A61B5/00
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
摘要翻译：本文公开了用于连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。一个这样的系统利用第一和第二工作电极来测量附加分析物或非分析物相关信号。这样的测量可以提供用于处理传感器数据的背景和/或灵敏度测量，并且可以用于触发诸如数据的数字滤波或暂停显示数据的事件。

60. 发明授权

US08911367B2 Analyte sensor 有权
公开(公告)号：US08911367B2
公开(公告)日：2014-12-16
申请号：US11691424
申请日：2007-03-26
申请人： Mark Brister , Mark Shults , Sean Saint , James R. Petisce , David K. Wong , Kum Ming Woo
发明人： Mark Brister , Mark Shults , Sean Saint , James R. Petisce , David K. Wong , Kum Ming Woo
IPC分类号： A61B5/00 , A61B5/145 , A61B5/1486 , A61B5/1495 , A61B5/1473 , A61M5/172 , A61M5/14 , A61M5/168
CPC分类号： A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/412 , A61B5/6848 , A61B5/6849 , A61B2560/0223 , A61M5/14 , A61M5/16804 , A61M5/1723 , A61M2230/201
摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

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