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51. 发明授权

US4857052A Intravenous system for delivering a beneficial agent 失效
标题翻译：用于递送有益药物的静脉内系统
公开(公告)号：US4857052A
公开(公告)日：1989-08-15
申请号：US45358
申请日：1987-05-04
申请人： Felix Theeuwes
发明人： Felix Theeuwes
IPC分类号： A61M5/14
CPC分类号： A61M5/1407
摘要： A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chamber. The chamber is adapted for use in an intravenous delivery system for delivering an agent formulation to a patient.
摘要翻译：公开了一种配制腔，其包括围绕包含用于递送有益剂的装置的内腔的壁。腔室具有用于允许流体进入腔室的入口和用于使药剂制剂离开腔室的出口。腔室适用于静脉输送系统，用于将药剂配制物递送给患者。

52. 发明授权

US4814180A Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container 失效
标题翻译：代理分配器包括围绕单件或两件式容器的半透壁
公开(公告)号：US4814180A
公开(公告)日：1989-03-21
申请号：US941971
申请日：1986-12-15
申请人： James B. Eckenhoff , Felix Theeuwes , Joseph C. Deters
发明人： James B. Eckenhoff , Felix Theeuwes , Joseph C. Deters
IPC分类号： A61K9/00 , A61K9/22 , A61M31/00 , A61K9/24 , A61K9/26 , A61K9/44
CPC分类号： A61K9/0004 , A61M31/002
摘要： A dispenser is disclosed for delivering a beneficial agent to an environment of use. The dispenser comprises a semipermeable wall surrounding a compartment containing a heat responsive composition, and an expandable composition. A passageway in the wall connects the compartment with the exterior of the dispenser.
摘要翻译：公开了一种用于将有益剂递送到使用环境的分配器。分配器包括围绕包含热响应组合物的隔室的半透壁和可膨胀组合物。墙壁上的通道将隔间与分配器的外部相连。

53. 发明授权

US4790820A Parenteral agent dispensing equipment with drug releasing member 失效
标题翻译：肠胃外给药装置与药物释放部件
公开(公告)号：US4790820A
公开(公告)日：1988-12-13
申请号：US664802
申请日：1984-10-25
申请人： Felix Theeuwes
发明人： Felix Theeuwes
IPC分类号： A61M5/14 , A61M5/00
CPC分类号： A61M5/1407
摘要： A parenteral delivery system and a formulation chamber are disclosed for administering a beneficial agent. The parenteral delivery system comprises a drip chamber and a formulation chamber. The formulation chamber comprises a wall surrounding an internal space and it has an inlet for admitting a liquid into the formulation chamber and an outlet for letting an agent formulation leave the formulation chamber. The chamber houses an agent delivery system for releasing a beneficial agent into a liquid that enters the chamber.
摘要翻译：公开了胃肠外递送系统和制剂室，用于施用有益剂。胃肠外输送系统包括滴注室和制剂室。制剂室包括围绕内部空间的壁，并且其具有用于将液体进入制剂室的入口和用于使制剂制剂离开制剂室的出口。该室容纳用于将有益剂释放到进入室的液体中的药剂递送系统。

54. 发明授权

US4783337A Osmotic system comprising plurality of members for dispensing drug 失效
标题翻译：渗透系统包括用于分配药物的多个构件
公开(公告)号：US4783337A
公开(公告)日：1988-11-08
申请号：US912712
申请日：1986-09-29
申请人： Patrick S.-L. Wong , Brian L. Barclay , Joseph C. Oeters , Felix Theeuwes
发明人： Patrick S.-L. Wong , Brian L. Barclay , Joseph C. Oeters , Felix Theeuwes
IPC分类号： A61K9/00 , A61K9/22 , A61M31/00
CPC分类号： A61K9/0004 , Y10S428/913 , Y10T428/249994
摘要： An osmotic system is disclosed comprising a wall comprising in at least a part of a semipermeable material that surrounds a compartment. The compartment contains a first osmotic composition comprising a beneficial drug selected from the group consisting of a calcium antagonist, angiotensin enzyme inhibitor and nonsteroidal antiinflammatory drugs, and a second and different osmotic composition. A passageway in the wall connects the first composition with the exterior of the system.
摘要翻译：公开了渗透系统，其包括围绕隔室的至少一部分半渗透材料的壁。隔室包含第一渗透组合物，其包含选自钙拮抗剂，血管紧张素酶抑制剂和非甾体抗炎药物的有益药物，以及第二和不同的渗透组合物。墙壁上的通道将第一个组合物与系统的外部连接起来。

55. 发明授权

US4765989A Osmotic device for administering certain drugs 失效
标题翻译：用于给予某些药物的渗透装置
公开(公告)号：US4765989A
公开(公告)日：1988-08-23
申请号：US902915
申请日：1986-09-02
申请人： Patrick S. L. Wong , Brian L. Barclay , Joseph C. Deters , Felix Theeuwes
发明人： Patrick S. L. Wong , Brian L. Barclay , Joseph C. Deters , Felix Theeuwes
IPC分类号： A61K9/00 , A61K9/22
CPC分类号： A61K9/0004
摘要： An osmotic system is disclosed comprising a wall comprising in at least a part of a semipermeable material that surrounds a compartment. The compartment contains an osmotic composition comprising a beneficial drug selected from the group consisting of nifedipine, prazosin and doxazosin, and a second and different osmotic composition. A passageway in the wall connects the first composition with the exterior of the system.
摘要翻译：公开了渗透系统，其包括围绕隔室的至少一部分半渗透材料的壁。隔室含有渗透组合物，其包含选自硝苯地平，哌唑嗪和多沙唑嗪的有益药物，以及第二和不同的渗透组合物。墙壁上的通道将第一个组合物与系统的外部连接起来。

56. 发明授权

US4751071A Composition comprising salbutamol 失效
标题翻译：组合物包含沙丁胺醇
公开(公告)号：US4751071A
公开(公告)日：1988-06-14
申请号：US1135
申请日：1987-01-07
申请人： Paul R. Magruder , Brian Barclay , Patrick S. L. Wong , Felix Theeuwes
发明人： Paul R. Magruder , Brian Barclay , Patrick S. L. Wong , Felix Theeuwes
IPC分类号： A61K9/00 , A61M31/00 , A61J3/07
CPC分类号： A61K9/0004 , A61M31/002
摘要： An osmotic delivery system is disclosed for delivering a useful agent at a controlled and constant rate modulated by a pulsed delivery of the useful agent to an environment of use.
摘要翻译：公开了一种渗透递送系统，用于以受控和恒定的速率递送有用的试剂，该有效试剂通过有用试剂的脉冲输送调节到使用环境。

57. 发明授权

US4740103A Intravenous system for delivering a beneficial agent 失效
公开(公告)号：US4740103A
公开(公告)日：1988-04-26
申请号：US702291
申请日：1985-02-15
申请人： Felix Theeuwes
发明人： Felix Theeuwes
IPC分类号： A61M5/14
CPC分类号： A61M5/1407
摘要： A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chamber. The chamber is adapted for use in an intravenous delivery system for delivering an agent formulation to a patient.

58. 发明授权

US4728498A Process for disinfecting article with device dispensing chlorine donor and chlorine acceptor 失效
标题翻译：用装置分配氯供体和氯受体消毒制品的方法
公开(公告)号：US4728498A
公开(公告)日：1988-03-01
申请号：US438049
申请日：1982-11-01
申请人： Felix Theeuwes
发明人： Felix Theeuwes
IPC分类号： A01N25/34 , A01N59/00 , A61L2/18
CPC分类号： A01N59/00 , A01N25/34
摘要： This invention concerns a process for disinfecting an article by placing the article in an aqueous environment comprising a device that dispenses a chlorine donor and a chlorine acceptor that generate a chlorine biocide for disinfecting the article.
摘要翻译：本发明涉及通过将制品置于包含分配氯供体的装置和产生用于消毒制品的氯生物杀灭剂的氯受体的含水环境中来消毒制品的方法。

59. 发明授权

US4525162A Parenteral controlled delivery 失效
标题翻译：肠外控制递送
公开(公告)号：US4525162A
公开(公告)日：1985-06-25
申请号：US587781
申请日：1984-03-09
申请人： John Urquhart , Felix Theeuwes
发明人： John Urquhart , Felix Theeuwes
IPC分类号： A61M5/14 , A61M5/16
CPC分类号： A61M5/1407
摘要： A parenteral delivery set is disclosed for administering a beneficial agent to a recipient. The set comprises (a) a primary container of a medical fluid; (b) a primary tubing in fluid communication with the primary container; (c) a secondary container of a medical fluid; (d) a secondary tubing in fluid communication with the secondary container; (e) a formulation chamber connected to the secondary tubing and housing an agent dispensing device or the beneficial agent; and (f) a common tubing in communication with the primary tubing and the secondary tubing for communicating the set to the recipient.
摘要翻译：公开了一种用于向接受者施用有益剂的胃肠外递送组。该组包括（a）医用流体的主要容器; （b）与主容器流体连通的主管; （c）药液的二次容器; （d）与次级容器流体连通的第二管道; （e）与第二管道连接并容纳药剂分配装置或有益药剂的制剂室; 和（f）与主管道和第二管道连通的通用管道，用于将设备传送到接收器。

60. 发明授权

US4511353A Intravenous system for delivering a beneficial agent 失效
公开(公告)号：US4511353A
公开(公告)日：1985-04-16
申请号：US310047
申请日：1981-10-09
申请人： Felix Theeuwes
发明人： Felix Theeuwes
IPC分类号： A61M5/14
CPC分类号： A61M5/1407
摘要： A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chamber. The chamber is adapted for use in an intravenous delivery system for delivering an agent formulation to a patient.

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