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51. 发明申请

WO2006010142A2 MINERALOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS 审中-公开
标题翻译：矿物化合物受体调节剂化合物和方法
公开(公告)号：WO2006010142A2
公开(公告)日：2006-01-26
申请号：PCT/US2005/024748
申请日：2005-07-12
申请人： LIGAND PHARMACEUTICALS, INC. , HIGUCHI, Robert I. , ZHI, Lin , ADAMS, Mark E. , LIU, Yan , KARANEWSKY, Donald S.
发明人： HIGUCHI, Robert I. , ZHI, Lin , ADAMS, Mark E. , LIU, Yan , KARANEWSKY, Donald S.
IPC分类号： C07D265/00
CPC分类号： C07D265/18 , C07D413/04
摘要： This invention relates to compounds that bind to mineralocorticoid receptors and/or modulate activity of mineralocorticoid receptors, and to methods for making and using such compounds.
摘要翻译：本发明涉及结合盐皮质激素受体的化合物和/或调节盐皮质激素受体的活性，以及制备和使用这些化合物的方法。

52. 发明申请

WO2002058625A2 HERBAL COMPOSITION FOR ANGINA PECTORIS, METHOD TO PREPARE SAME AND USES THEREOF 审中-公开
标题翻译：神经酰胺的草本组合物，其制备方法及其用途
公开(公告)号：WO2002058625A2
公开(公告)日：2002-08-01
申请号：PCT/US2001/049396
申请日：2001-12-18
申请人： TIANJIN TASLY PHARMACEUTICAL CO., LTD., CHINA , CARDIONAT, INC. , YAN, Xijun , WU, Naifeng , GUO, Zhixin , YE, Zhengliang , LIU, Yan
发明人： YAN, Xijun , WU, Naifeng , GUO, Zhixin , YE, Zhengliang , LIU, Yan
IPC分类号： A61K
CPC分类号： A61K36/258 , A61K36/537 , A61K2300/00
摘要： This invention provides compositions comprising extracts of Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneol. Said compositions comprise notoginsenoside R 1 and ginsenoside R g1 which are active components for therapeutic applications. This invention also provides a method of preparation of the said compositions and a method of identification and determination of the amount of individual effective components of said compositions. Finally, this invention provides various uses of the compositions.
摘要翻译：本发明提供了含有丹参，三七和冰片的提取物的组合物。所述组合物包含作为治疗应用的活性成分的三七皂苷R1和人参皂甙Rg1。本发明还提供了所述组合物的制备方法和鉴定和测定所述组合物的各个有效成分的量的方法。最后，本发明提供了组合物的各种用途。

53. 发明申请

WO2014134338A1 OLIGONUCLEOTIDE FUNCTIONALIZED QUANTUM DOTS 审中-公开
标题翻译：寡核苷酸官能化量子点
公开(公告)号：WO2014134338A1
公开(公告)日：2014-09-04
申请号：PCT/US2014/019094
申请日：2014-02-27
申请人： ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY , YAN, Hao , LIU, Yan , DENG, Zhengtao , SAMANTA, Anirban
发明人： YAN, Hao , LIU, Yan , DENG, Zhengtao , SAMANTA, Anirban
IPC分类号： G01N21/64 , H01L21/54
CPC分类号： C12Q1/6825 , B82Y15/00 , B82Y40/00 , C07H21/00 , C12Q1/6834 , G01N33/588 , Y10S977/774 , Y10S977/795 , Y10S977/824 , Y10S977/901
摘要： The present invention provides a DNA-functionalized conjugate comprising single-stranded DNA (ssDNA) strands conjugated to a semiconductor nanoparticle, wherein the nanoparticle provides fluorescent emissions. The present invention also provides a method to efficiently conjugate DNA strands to a wide variety of quantum dots having fluorescent emissions covering from UV-visible to infrared.
摘要翻译：本发明提供包含与半导体纳米颗粒共轭的单链DNA（ssDNA）链的DNA官能化缀合物，其中所述纳米颗粒提供荧光发射。本发明还提供了一种有效地将DNA链共轭到具有从UV-可见到红外线的荧光发射的多种量子点的方法。

54. 发明申请

WO2013103836A2 METHODS OF TREATING CANCER 审中-公开
标题翻译：癌症治疗方法
公开(公告)号：WO2013103836A2
公开(公告)日：2013-07-11
申请号：PCT/US2013/020310
申请日：2013-01-04
申请人： DANA-FARBER CANCER INSTITUTE, INC. , WONG, Kwok-Kin , LIU, Yan
发明人： WONG, Kwok-Kin , LIU, Yan
IPC分类号： A61K31/7088
CPC分类号： C12N15/1137 , A61K31/407 , A61K31/415 , A61K31/4535 , A61K31/497 , A61K31/513 , A61K31/55 , A61K31/5517 , A61K31/553 , A61K31/7068 , A61K31/7072 , A61K39/3955 , A61K45/06 , C07K16/40 , G01N33/5011 , A61K2300/00
摘要： The present invention provides methods of treating cancer, particularly cancers that are null or have decreased expression or activity of the Lkbl gene. Also included are methods of identifying therapeutic targets for the treatment of cancer.
摘要翻译：本发明提供了治疗癌症的方法，特别是无效或具有降低的Lkb1基因的表达或活性的癌症。还包括鉴定用于治疗癌症的治疗靶标的方法。

55. 发明申请

WO2012099743A1 METHOD AND SYSTEM FOR PROCESSING VIDEO DATA 审中-公开
标题翻译：用于处理视频数据的方法和系统
公开(公告)号：WO2012099743A1
公开(公告)日：2012-07-26
申请号：PCT/US2012/020707
申请日：2012-01-10
申请人： GENERAL INSTRUMENT CORPORATION , NARASIMHAN, Nitya , LIU, Yan , SINGER, Gregory L.
发明人： NARASIMHAN, Nitya , LIU, Yan , SINGER, Gregory L.
IPC分类号： H04N7/26 , H04N7/30 , H03M7/40
CPC分类号： H04N19/129 , H03M7/4018 , H03M7/6023 , H04N19/13 , H04N19/176 , H04N19/18 , H04N19/436 , H04N19/463
摘要： In various embodiments, a significance map of a matrix of video data coefficients is encoded or decoded using context-based adaptive binary arithmetic coding (CABAC). The significance map scanned line-by-line along a scanning pattern. Each line may be a vertical, horizontal, or diagonal section of the scanning pattern. Context models for each element processed in a particular line are chosen based on values of neighboring elements that are not in the line. Avoiding reliance on neighbors that are in the same line facilitates parallel processing.
摘要翻译：在各种实施例中，使用基于上下文的自适应二进制算术编码（CABAC）对视频数据系数矩阵的显着图进行编码或解码。沿着扫描模式逐行扫描的重要性图。每行可以是扫描图案的垂直，水平或对角线部分。基于不在行中的相邻元素的值来选择在特定行中处理的每个元素的上下文模型。避免依赖同一行中的邻居有助于并行处理。

56. 发明申请

WO2011133417A2 COATED GRAPHITE ARTICLE AND REACTIVE ION ETCH MANUFACTURING AND REFURBISHMENT OF GRAPHITE ARTICLE 审中-公开
标题翻译：涂层石墨制品和石墨制品的反应离子生产和改造
公开(公告)号：WO2011133417A2
公开(公告)日：2011-10-27
申请号：PCT/US2011/032662
申请日：2011-04-15
申请人： ENTEGRIS, INC. , COOKE, Richard, A. , GUNDA, Nilesh , DONNELL, Steven , LIU, Yan
发明人： COOKE, Richard, A. , GUNDA, Nilesh , DONNELL, Steven , LIU, Yan
IPC分类号： H01B5/14 , H01J37/317
CPC分类号： C23C14/48 , H01B5/14 , H01J37/16 , H01J37/3171 , Y10T428/265 , Y10T428/30
摘要： In accordance with an embodiment of the invention, there is provided a coated graphite article. The article comprises graphite; and a conductive coating overlaying at least a portion of the graphite. The conductive coating comprises a through-thickness resistance of less than about 50 ohms as measured through the thickness of the graphite and the conductive coating. In accordance with another embodiment of the invention, there is provided a method for manufacturing a graphite article comprising a conductive coating. The method comprises treating graphite of the article with a reactive ion etch process; and after treating the graphite with the reactive ion etch process, applying the conductive coating over at least a portion of the graphite. In a further embodiment according to the invention, there is provided a method for refurbishing a graphite article comprising graphite and an overlaying conductive coating. The method comprises removing the overlaying conductive coating of the graphite article with a reactive ion etch process; and applying a new conductive coating over at least a portion of the graphite.
摘要翻译：根据本发明的实施例，提供了一种涂覆石墨制品。该物品包括石墨; 以及覆盖至少一部分石墨的导电涂层。导电涂层包括通过石墨和导电涂层的厚度测量的小于约50欧姆的贯穿厚度电阻。根据本发明的另一个实施例，提供了一种用于制造包括导电涂层的石墨制品的方法。该方法包括用反应离子蚀刻工艺处理制品的石墨; 并且在用反应离子蚀刻工艺处理石墨之后，将导电涂层施加在石墨的至少一部分上。在根据本发明的另一实施例中，提供了一种用于翻新包含石墨和覆盖导电涂层的石墨制品的方法。该方法包括用反应离子蚀刻工艺去除石墨制品的覆盖导电涂层; 以及在所述石墨的至少一部分上施加新的导电涂层。

57. 发明申请

WO2011091030A1 MULTICHANNEL ION CHROMATOGRAPHY SYSTEM AND METHOD 审中-公开
标题翻译：多通道离子色谱系统和方法
公开(公告)号：WO2011091030A1
公开(公告)日：2011-07-28
申请号：PCT/US2011/021706
申请日：2011-01-19
申请人： DIONEX CORPORATION , LIU, Yan , KUSE, Glenn, Masami , BARRETO, Victor , GLEAVE, Gary , POHL, Christopher, A. , CASE, William, Dale , MOSHFEGH, Khosro , McADAMS, Michael, John
发明人： LIU, Yan , KUSE, Glenn, Masami , BARRETO, Victor , GLEAVE, Gary , POHL, Christopher, A. , CASE, William, Dale , MOSHFEGH, Khosro , McADAMS, Michael, John
IPC分类号： B01D15/08
CPC分类号： G01N30/96 , G01N30/6091 , G01N2030/8881 , G01N2030/965
摘要： An ion chromatography housing for easy insertion and removal of a plurality of component cartridges is disclosed. Various components of the IC system are provided in the separate component cartridges. The IC housing includes a capillary separation column and may be connected to conventional-scale components of an IC system. A plurality of IC housings may be provided in a compartment with one or more separation columns. The columns may be capillary columns or conventional-scale columns. A method of using the ion chromatography system is also disclosed. The IC system may be utilized to perform two-dimensional ion chromatographic separation.
摘要翻译：公开了用于容易地插入和移除多个组件盒的离子色谱盒。 IC系统的各种组件设置在分开的组件盒中。 IC壳体包括毛细管分离柱，并且可以连接到IC系统的常规尺寸部件。多个IC壳体可以设置在具有一个或多个分离柱的隔间中。柱可以是毛细管柱或常规尺度的柱。还公开了使用离子色谱系统的方法。 IC系统可用于进行二维离子色谱分离。

58. 发明申请

WO2011082351A1 A POLYMER AND METHODS OF PREPARING AND USING A POLYMER 审中-公开
标题翻译：聚合物和制备和使用聚合物的方法
公开(公告)号：WO2011082351A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/062578
申请日：2010-12-30
申请人： CARGILL, INCORPORATED , BILLING, Johan , ERIKSSON, Jonas , KARLSSON, Ola , LIU, Yan , STARK, Christian Svensson , YILMAZ, Ecevit
发明人： BILLING, Johan , ERIKSSON, Jonas , KARLSSON, Ola , LIU, Yan , STARK, Christian Svensson , YILMAZ, Ecevit
IPC分类号： B32B3/26
CPC分类号： B01J20/262 , B01D15/325 , B01J20/261 , B01J20/264 , B01J20/28061 , B01J20/28064 , B01J20/28073 , B01J20/28076 , B01J20/28083 , B01J20/285 , C07D209/20 , C08F212/08 , C08F212/36
摘要： Methods for preparing a polymer using Hansen solubility parameters are described. Also described is a polymer having certain properties, including those related to the Hansen solubility parameters, having utility in the separation of monatin from a monatin-containing mixture.
摘要翻译：描述了使用汉森溶解度参数制备聚合物的方法。还描述了具有某些性质的聚合物，包括与Hansen溶解度参数相关的特性，可用于从含monatin的混合物中分离莫纳甜。

59. 发明申请

WO2009141769A1 REPRODUCIBLE POSITIONING OF SENSING AND/OR TREATMENT DEVICES 审中-公开
标题翻译：感测和/或治疗装置的重新定位
公开(公告)号：WO2009141769A1
公开(公告)日：2009-11-26
申请号：PCT/IB2009/051998
申请日：2009-05-14
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , LIU, Yan , VON BASUM, Golo , MOESKOPS, Bastiaan, W., M. , CIUHU, Calina , THUMMA, Kiran, K.
发明人： LIU, Yan , VON BASUM, Golo , MOESKOPS, Bastiaan, W., M. , CIUHU, Calina , THUMMA, Kiran, K.
IPC分类号： A61B5/06 , G06T7/00 , A61B19/00
CPC分类号： A61B5/6842 , A61B5/0059 , A61B5/0066 , A61B5/061 , A61B5/064 , A61B5/14532 , A61B5/441 , A61B5/6843 , A61B34/20 , A61B34/70 , A61B90/90 , A61B2034/2065 , A61B2090/373 , A61B2090/3937 , A61B2090/395 , A61B2562/02 , G06F19/00 , G06T7/33 , G06T2207/30088 , G06T2207/30101 , G06T2207/30204
摘要： The present invention provides a repositioning system (10) for positioning a sensing and/or treatment device (6) at a target location (16), the repositioning system (10) comprising an imaging system (2) for identifying a target location (16) having a marker (12) on a body part (11) of a human being or an animal, thereby obtaining a reference image (13) ofthe target location (16), and for acquiring at least one measured image (14) of the target location (16).The imaging system (2) furthermore comprises registration means (3) for registering the at least one measured image (14) to the reference image (13), and signal generating means for generating a driving signal (5) indicative of the target location direction when spatial alignment between the at least one measured image (14) and reference image (13) is not approached within a predetermined threshold value. The repositioning system (10) furthermore comprises actuator means (4) for driving the sensing and/or treatment device (6) to guide it towards the target location thereby using the driving signal (5). The present invention also provides a method for making such a repositioning system (10) and a method for positioning a sensing and/or treatment device (6) on a target location (16) on a body part (11) of a human being or an animal by using such a repositioning system (10).
摘要翻译：本发明提供一种用于将感测和/或治疗装置（6）定位在目标位置（16）处的重新定位系统（10），所述重新定位系统（10）包括用于识别目标位置（16）的成像系统（2））在人或动物的身体部分（11）上具有标记（12），从而获得目标位置（16）的参考图像（13），并且用于获取至少一个测量图像（14）目标位置（16）。成像系统（2）还包括用于将至少一个测量图像（14）登记到参考图像（13）的登记装置（3）和用于产生驱动信号（5）的信号产生装置指示在所述至少一个测量图像（14）和参考图像（13）之间的空间对准未在预定阈值内接近时的所述目标位置方向。重新定位系统（10）还包括用于驱动感测和/或治疗装置（6）以将其引向目标位置的致动器装置（4），从而使用驱动信号（5）。本发明还提供了一种用于制造这种重新定位系统（10）的方法和用于将感测和/或治疗装置（6）定位在人的身体部分（11）上的目标位置（16）上的方法，或通过使用这种重新定位系统（10）的动物。

60. 发明申请

WO2009105387A1 ION CHROMATOGRAPHY SYSTEMS WITH FLOW-DELAY ELUENT RECYCLE 审中-公开
标题翻译：离子色谱系统与流延迟回收
公开(公告)号：WO2009105387A1
公开(公告)日：2009-08-27
申请号：PCT/US2009/034015
申请日：2009-02-13
申请人： DIONEX CORPORATION , LIU, Yan , SRINIVASAN, Kannan , POHL, Christopher, A. , BHARDWAJ, Sheetal , LU, Zhongqing
发明人： LIU, Yan , SRINIVASAN, Kannan , POHL, Christopher, A. , BHARDWAJ, Sheetal , LU, Zhongqing
IPC分类号： G01N30/96
CPC分类号： B01D15/10 , G01N30/26 , G01N30/96 , G01N2030/965
摘要： A chromatographic method including chromatographically separating sample ionic species in an eluent stream, detecting the separated sample ionic species, catalytically combining hydrogen and oxygen gases or catalytically decomposing hydrogen peroxide in a catalytic gas elimination chamber (31), and recycling the effluent stream from the catalytic gas elimination chamber to the chromatography separation column (10). The residence time between the detector (14) and said chamber (31) is at least one minute to facilitate decomposition of unstable oxidative compounds. Also, flowing the recycle sequentially through two detector effluent flow channels of an electrolytic membrane suppressor (28). Also, applying heat or UV energy between the detector (14) and the chamber (31). Also, detecting bubbles after the chamber. Also, a Platinum group metal catalyst and ion exchange medium in the chamber. Apparatus for performing the methods.
摘要翻译：一种色谱方法，包括在洗脱液流中色谱分离样品离子物质，检测分离的样品离子物质，催化结合氢气和氧气，或催化分解催化气体消除室（31）中的过氧化氢，以及将来自催化剂的流出物流气体消除室至色谱分离柱（10）。检测器（14）和所述室（31）之间的停留时间为至少一分钟，以促进不稳定的氧化化合物的分解。此外，使循环物依次流过电解膜抑制器（28）的两个检测器流出物流动通道。而且，在检测器（14）和腔室（31）之间施加热或UV能量。另外，在室后检测气泡。此外，铂族金属催化剂和离子交换介质在室内。用于执行方法的装置。

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