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51. 发明授权

US5426194A Isolation and structure of Halistatin 1 失效
标题翻译： Halistatin的分离和结构1
公开(公告)号：US5426194A
公开(公告)日：1995-06-20
申请号：US4851
申请日：1993-01-19
申请人： George R. Pettit , Rui Tan , Feng Gao
发明人： George R. Pettit , Rui Tan , Feng Gao
IPC分类号： A61K31/365 , A61K35/00 , A61K35/02 , A61K35/56 , A61P35/00 , A61P35/02 , C07D493/22 , C07H9/02 , C12P17/18 , C12P19/44 , C07D323/00
CPC分类号： C07H9/02 , C07D493/22 , C12P17/181 , C12P19/445
摘要： An intensive long-term investigation of marine organisms as sources of new anticancer drugs has led to the isolation and structural elucidation (primarily by high field NMR and mass spectrometry) of halistatin 1, a new polyether macrolide of the halipyran-type, from the Western Indian Ocean sponge Phakellia carteri. Halistatin 1 (8.8.times.10.sup.-7 % yield) caused the accumulation of cells arrested in mitosis, inhibited tubulin polymerization, and inhibited the binding of radiolabeled vinblastine and GTP to tubulin.
摘要翻译：对海洋生物进行深入的长期调查，作为新的抗癌药物的来源，导致了halistatin 1（Halipyran型的新型聚醚大环内酯类）的隔离和结构解释（主要是通过高场NMR和质谱），来自西方印度洋海绵Phakellia carteri。 Halistatin 1（8.8×10-7％产率）引起细胞中有丝分裂停滞的积累，抑制微管蛋白聚合，并抑制放射性标记的长春花碱和GTP与微管蛋白的结合。

52. 发明授权

US09944528B2 Carbon nanostructure synthesis 有权
公开(公告)号：US09944528B2
公开(公告)日：2018-04-17
申请号：US15159228
申请日：2016-05-19
申请人： Guang-Lin Zhao , Feng Gao , Zhou Wang
发明人： Guang-Lin Zhao , Feng Gao , Zhou Wang
IPC分类号： C01B31/02 , C01B32/15 , C01B32/162 , B82Y40/00
CPC分类号： C01B32/162 , B82Y40/00 , C01B32/15 , Y10S977/742 , Y10S977/842
摘要： Methods of making carbon nanostructures are disclosed with including examples having heat treatment of a mixture having a fibrous organic reagent and a catalyst in the presence of a reducing agent for a time sufficient to produce a quantity of carbon nanostructures which may be nanotubes or other related structures. The reducing agent may be hydrogen, nitrogen or ammonia.

53. 发明授权

US09687023B2 Moist smokeless tobacco product for oral usage having on a portion of the outer surface at least one friction reducing strip that provides texture during use 有权
公开(公告)号：US09687023B2
公开(公告)日：2017-06-27
申请号：US12576986
申请日：2009-10-09
申请人： Munmaya K. Mishra , Shengsheng Liu , William R. Sweeney , Feng Gao , Tapashi Sengupta
发明人： Munmaya K. Mishra , Shengsheng Liu , William R. Sweeney , Feng Gao , Tapashi Sengupta
IPC分类号： A24B13/00 , A24B15/18
CPC分类号： A24B13/00 , A24B15/186
摘要： A moist smokeless tobacco product for oral use comprises a pre-portioned piece of tobacco material semi-dissolvable, a super-hydrated membrane coating comprising a soluble, non-cross-linked component and an insoluble, cross-linked component, and a texture component. The tobacco material comprises moist smokeless tobacco. The texture component reduces the slipperiness and/or increases the friction of the moist smokeless tobacco product when placed in a user's mouth.

54. 发明授权

US08879865B2 Panchromatic sharpening method of spectral image based on fusion of overall structural information and spatial detail information 有权
标题翻译：基于整体结构信息和空间细节信息融合的光谱图像的全色锐化方法
公开(公告)号：US08879865B2
公开(公告)日：2014-11-04
申请号：US14082948
申请日：2013-11-18
申请人： Bo Li , Qizhi Xu , Yue Tian , Feng Gao , Chen Zhong
发明人： Bo Li , Qizhi Xu , Yue Tian , Feng Gao , Chen Zhong
IPC分类号： G06K9/40 , G06T5/00
CPC分类号： G06T5/50 , G06T5/004 , G06T2207/10024 , G06T2207/20221
摘要： The present invention provides a panchromatic sharpening method of spectral image based on fusion of overall structural information and spatial detail information, comprising: performing brightness linear stretching on a panchromatic image, so as to set the variance of the panchromatic image to be equal to the variance of said spectral image; respectively interpolating N components of the spectral image so as to generate an interpolation image series having the same resolution as that of the panchromatic image; subtracting the interpolation image series from the panchromatic image after said linear stretching to obtain difference images; performing Gauss filtering on the difference images, thereby obtaining difference tendency images; and, respectively subtracting the difference tendency image series from the panchromatic image after said linear stretching, thus obtaining fused images. The method can maintain both spectral fidelity and texture detail fidelity of the fused images, support high computation speed, and has wide applicability.
摘要翻译：本发明提供了一种基于整体结构信息和空间细节信息的融合的光谱图像的全色锐化方法，包括：在全色图像上执行亮度线性拉伸，以将全色图像的方差设置为等于方差的所述光谱图像; 分别内插所述光谱图像的N个分量，以产生具有与全色图像相同分辨率的内插图像序列; 在所述线性拉伸之后从全色图像中减去插值图像序列以获得差分图像; 对差分图像执行高斯滤波，从而获得差异趋势图像; 并且在所述线性拉伸之后分别从全色图像中减去差异趋势图像序列，从而获得融合图像。该方法可以保持融合图像的光谱保真度和纹理细节保真度，支持高计算速度，具有广泛的适用性。

55. 发明授权

US08551723B2 Tyrosine kinase-inducible domains 有权
标题翻译：酪氨酸激酶诱导区
公开(公告)号：US08551723B2
公开(公告)日：2013-10-08
申请号：US13078494
申请日：2011-04-01
申请人： Neal J. Zondlo , Susan Carr Zondlo , Feng Gao
发明人： Neal J. Zondlo , Susan Carr Zondlo , Feng Gao
IPC分类号： C12Q1/48 , C07K7/08
CPC分类号： C12Q1/485 , C07K7/08
摘要： The present invention relates to a tyrosine kinase-inducible domain (pKID) and uses thereof. An isolated polypeptide comprising the pKID, and an isolated polynucleotide comprising a nucleic acid sequence encoding the pKID are provided. Also provided are methods for determining tyrosine kinase and/or phosphatase activity in a sample and for identifying an agent that inhibits a tyrosine kinase or phosphatase using a polypeptide comprising the pKID.
摘要翻译：本发明涉及酪氨酸激酶诱导结构域（pKID）及其用途。提供了包含pKID的分离的多肽和包含编码pKID的核酸序列的分离的多核苷酸。还提供了用于在样品中测定酪氨酸激酶和/或磷酸酶活性并鉴定使用包含pKID的多肽来抑制酪氨酸激酶或磷酸酶的试剂的方法。

56. 发明申请

US20130215832A1 BROADBAND DUAL-POLARIZED OMNI-DIRECTIONAL ANTENNA AND FEEDING METHOD USING THE SAME 有权
标题翻译：宽带双极化OMNI方向天线和使用它的馈电方法
公开(公告)号：US20130215832A1
公开(公告)日：2013-08-22
申请号：US13878142
申请日：2011-10-08
申请人： Feng Gao , Huaxing Ma , Peng Gao , Yuan Jiang , Jiwei He , Wentao Zhu , Xu Liu , Dongchen Zhang
发明人： Feng Gao , Huaxing Ma , Peng Gao , Yuan Jiang , Jiwei He , Wentao Zhu , Xu Liu , Dongchen Zhang
IPC分类号： H01Q21/26
CPC分类号： H01Q21/26 , H01Q9/26
摘要： A broadband dual-polarized omni-directional antenna and a feeding method using the same are provided. By setting a vertically polarized antenna and a horizontally polarized antenna each in co-axial, the horizontally polarized antenna is attached to an upper surface and a lower surface of the attaching plate respectively by two arms of a folded dipole and the two arms connect to an inner conductor and an outer conductor of a feed line so that the dual-polarized antenna may have a comparatively broad bandwidth. At the same time, since the dual-polarized ceiling antenna has a good isolation effect and coverage balance, it may work as the MIMO antenna in the LTE and WLAN systems effectively and may be used in the 2G and 3G networks to improve the data transmission rate.
摘要翻译：提供了一种宽带双极化全向天线及其使用方法。通过设置同轴的垂直极化天线和水平极化天线，水平极化的天线分别通过折叠偶极子的两个臂附接到安装板的上表面和下表面，并且两个臂连接到内部导体和馈电线的外部导体，使得双极化天线可以具有相对宽的带宽。同时，由于双极化天花板天线具有良好的隔离效果和覆盖平衡，因此可以有效地在LTE和WLAN系统中作为MIMO天线工作，并可用于2G和3G网络，以改善数据传输率。

57. 发明授权

US08290265B2 Method and apparatus for segmenting an object region of interest from an image 有权
标题翻译：用于从图像中分割目标区域的方法和装置
公开(公告)号：US08290265B2
公开(公告)日：2012-10-16
申请号：US12331160
申请日：2008-12-09
申请人： Feng Gao , Na Zhou , Wei Liu , Huai Yuan
发明人： Feng Gao , Na Zhou , Wei Liu , Huai Yuan
IPC分类号： G06K9/34 , G06K9/62 , G06K9/00
CPC分类号： G06K9/3241 , G06K9/00791 , G06K2209/23 , G06T7/12 , G06T2207/30248
摘要： A method for segmenting an object region of interest from an image includes detecting each corner in a captured image; acquiring edges of the object from the captured image based on the detected corners; clustering the detected corners based on corners on the acquired edges; and segmenting the image region in the captured image formed by the clustered corners as a region of interest that likely includes the object. With this method and apparatus for the method, an object region of interest may be segmented from an image without utilizing features such as an object shadow and edges.
摘要翻译：从图像中分割目标区域的方法包括：检测拍摄图像中的每个角; 基于检测到的拐角从捕获的图像获取对象的边缘; 基于所获取的边缘上的角聚类检测到的角; 并且将由聚集角形成的拍摄图像中的图像区域分割为可能包括对象的感兴趣区域。利用该方法和该方法的装置，可以从图像中分割关注的对象区域，而不利用诸如对象阴影和边缘的特征。

58. 发明授权

US08071107B2 Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins 有权
标题翻译：编码修饰的人类免疫缺陷病毒1型（HIV-1）组的核酸M共有包膜糖蛋白
公开(公告)号：US08071107B2
公开(公告)日：2011-12-06
申请号：US10572638
申请日：2004-09-17
申请人： Barton F. Haynes , Feng Gao , Bette T. Korber , Beatrice H. Hahn , George M. Shaw , Denise Kothe , Ying Ying Li , Julie Decker , Hua-Xin Liao
发明人： Barton F. Haynes , Feng Gao , Bette T. Korber , Beatrice H. Hahn , George M. Shaw , Denise Kothe , Ying Ying Li , Julie Decker , Hua-Xin Liao
IPC分类号： A61K39/21 , C07H21/04
CPC分类号： A61K39/21 , A61K39/12 , A61K2039/53 , A61K2039/57 , C07K14/005 , C07K16/4225 , C12N2740/15022 , C12N2740/15034 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16222 , C12N2740/16322
摘要： The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.
摘要翻译：本发明一般涉及免疫原，特别涉及用于诱导中和大范围的HIV初级分离物和/或诱导T细胞免疫应答的免疫原的抗体的免疫原。本发明还涉及使用这种免疫原诱导抗HIV抗体的方法和/或诱导T细胞免疫应答的方法。本发明还涉及编码本发明免疫原的核酸序列。

59. 发明授权

US08060733B2 Apparatus for displaying BIOS POST code and method thereof 有权
标题翻译：用于显示BIOS POST代码的装置及其方法
公开(公告)号：US08060733B2
公开(公告)日：2011-11-15
申请号：US12191760
申请日：2008-08-14
申请人： Feng Gao
发明人： Feng Gao
IPC分类号： G06F9/24
CPC分类号： G06F11/2284
摘要： An apparatus for displaying a basic input output system (BIOS) power-on self-test (POST) code and a method thereof are provided. The apparatus includes a BIOS, a conversion module, and an output module. The BIOS is used for generating a POST code. The POST code is transmitted via a low pin count (LPC) interface. The conversion module receives the POST code and converts the POST code into a system management bus (SMBus) format. The output module is used for receiving and outputting the POST code transmitted by the conversion module. The output module is an SMBus interface.
摘要翻译：提供一种用于显示基本输入输出系统（BIOS）开机自检（POST）代码的装置及其方法。该装置包括BIOS，转换模块和输出模块。 BIOS用于生成POST代码。 POST代码通过低引脚数（LPC）接口传输。转换模块接收POST代码，并将POST代码转换为系统管理总线（SMBus）格式。输出模块用于接收和输出由转换模块发送的POST代码。输出模块是SMBus接口。

60. 发明申请

US20100285106A1 MULTICOMPONENT VACCINE 审中-公开
标题翻译：多发性疫苗
公开(公告)号：US20100285106A1
公开(公告)日：2010-11-11
申请号：US12312587
申请日：2007-11-19
申请人： Barton F. Haynes , Nancy G. Smith , S.Munir Alam , Feng Gao , Hua-Xin Liao
发明人： Barton F. Haynes , Nancy G. Smith , S.Munir Alam , Feng Gao , Hua-Xin Liao
IPC分类号： A61K39/21 , A61K9/127 , A61K39/395 , A61P31/18 , A61P37/04
CPC分类号： C07K14/005 , A61K39/12 , A61K39/21 , A61K39/385 , A61K39/39 , A61K39/39533 , A61K39/3955 , A61K39/42 , A61K2039/5256 , A61K2039/53 , A61K2039/55516 , A61K2039/55555 , A61K2039/55561 , A61K2039/55566 , A61K2039/6018 , C07K2319/04 , C12N15/86 , C12N2740/16122 , C12N2740/16134 , C12N2760/20243
摘要： The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to a multicomponent vaccine and method of using same to protect against HTV-I infection.
摘要翻译：本发明一般涉及人类免疫缺陷病毒（HIV），特别涉及一种多组分疫苗及其使用方法来防止HTV-1感染。

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