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51. 发明申请

US20070170953A1 System and method for extending universal bus line length 有权
标题翻译：扩展通用总线长度的系统和方法
公开(公告)号：US20070170953A1
公开(公告)日：2007-07-26
申请号：US11434458
申请日：2006-05-15
申请人： Lance Weston , Tony Li , John Ryan
发明人： Lance Weston , Tony Li , John Ryan
IPC分类号： H03K19/003
CPC分类号： G06F13/4072 , H04B1/62 , H04B3/06
摘要： A system and method for recovering a high frequency component of a slew rate controlled signal propagating along a transmission line enables the high frequency component to be recovered after being lost because of slew rate control and transmission line low pass filtering effects. The system includes a wave shaping circuit for receiving and shaping the slew rate controlled signal to recover the high frequency component. The method includes receiving the slew rate controlled signal, and recovering the high frequency component by shaping the slew rate controlled signal to produce a shaped signal, where the shaped signal includes the received slew rate controlled signal and the high frequency component.
摘要翻译：用于恢复沿着传输线传播的转换速率控制信号的高频分量的系统和方法使得能够在由于压摆率控制和传输线低通滤波效应而在丢失之后恢复高频分量。该系统包括波形整形电路，用于接收和整形转换速率控制信号以恢复高频分量。该方法包括接收压摆率控制信号，并通过整形转换速率控制信号来恢复高频分量，以产生成形信号，其中成形信号包括接收转换速率控制信号和高频分量。

52. 发明申请

US20070065584A1 Spray-on paint protection film and method of applying same 审中-公开
标题翻译：喷漆保护膜及其应用方法
公开(公告)号：US20070065584A1
公开(公告)日：2007-03-22
申请号：US10595539
申请日：2004-10-25
申请人： John Ryan , Eric Rosenthal , Richard Granito
发明人： John Ryan , Eric Rosenthal , Richard Granito
IPC分类号： B05D1/32 , B05D3/02 , B05D1/02 , C08F20/00
CPC分类号： C09D175/06 , B05D1/32 , B05D5/00 , B05D5/005 , B05D7/14 , B05D7/57 , C08L67/00 , C08L75/04 , C08L2666/20
摘要： A method of protecting the paint on a vehicle from being chipped, scratched or corroded, comprising the steps of: (a) masking off those parts of the vehicle that are not to be coated; (b) spraying the remaining parts of the vehicle with a clear, protective coating to a thickness of four to fourteen mils or to a thickness that is three to five times the thickness of an OEM clear coat; (c) allowing the vehicle to air dry or force curing the vehicle with heat lamps; and (d) unmasking the vehicle. A spray-on protection film comprising a mixture of polyester resins and a high solids aliphatic polyisocyanate resin hardener, wherein the film is sprayed onto all or part of a vehicle to a thickness of four to fourteen mils or to a thickness that is three to five times the thickness of an OEM clear coat.
摘要翻译：一种保护车辆上的油漆不会被切屑，划伤或腐蚀的方法，包括以下步骤：（a）遮蔽那些未被涂覆的车辆部分; （b）用清洁的保护涂层将车辆的其余部分喷涂至4至14密耳的厚度或厚度为OEM透明涂层厚度的3至5倍的厚度; （c）允许车辆用热灯空气干燥或强制固化车辆; 和（d）揭开车辆。一种喷涂保护膜，其包含聚酯树脂和高固体脂肪族多异氰酸酯树脂固化剂的混合物，其中将膜喷涂到四分之一至十四密耳的厚度或三至五个厚度的载体的全部或部分上倍的厚度的OEM清漆。

53. 发明申请

US20050148437A1 Portable simulated pulling apparatus 有权
标题翻译：便携式模拟牵引装置
公开(公告)号：US20050148437A1
公开(公告)日：2005-07-07
申请号：US10753038
申请日：2004-01-07
申请人： John Ryan , Joseph DiGuglielmo
发明人： John Ryan , Joseph DiGuglielmo
IPC分类号： A63B9/00 , A63B21/00 , A63B21/018 , A63B21/068 , A63B23/12
CPC分类号： A63B21/018 , A63B7/045 , A63B21/00069 , A63B21/4035 , A63B21/4043 , A63B23/03525 , A63B23/03533 , A63B23/12 , A63B23/1209
摘要： A portable simulated pulling exercise apparatus includes an upright support and a variable resistance head member lockably and pivotably connected to the upright support in an adjustable manner. A continuous pulling member runs through the variable resistance head and is pulled by a user. The user can determine the variable pulling resistance and adjust a head member pivot range with a degree of pivot through various degrees of freedom. The Apparatus is collapsible and repositionable for user convenience and portability.
摘要翻译：便携式模拟拉动锻炼装置包括直立支撑件和可变阻力头部构件，其以可调节的方式可锁定且可枢转地连接到直立支撑件。连续牵引构件穿过可变阻力头并由使用者拉动。用户可以确定可变牵引阻力，并通过各种自由度以一定程度的枢轴调节头部构件枢轴范围。该装置可折叠和可重新定位，以便用户方便和便携。

54. 发明申请

US20160166567A1 TREATMENT OF CANCER 审中-公开
公开(公告)号：US20160166567A1
公开(公告)日：2016-06-16
申请号：US14800234
申请日：2015-07-15
申请人： John Ryan
发明人： John Ryan
IPC分类号： A61K31/4745 , A61K31/44 , A61K47/48
CPC分类号： A61K31/4745 , A61K31/44 , A61K47/61 , C07D491/22 , C07D519/00
摘要： Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.

55. 发明申请

US20140335362A1 METHOD AND COMPOSITION RE POLYURETHANE SEATING 有权
标题翻译：方法和组合RE聚氨酯泡沫
公开(公告)号：US20140335362A1
公开(公告)日：2014-11-13
申请号：US13890377
申请日：2013-05-09
申请人： Terry Cassaday , John Ryan , Paul Thottathil , Purushothaman Kesavan , Satyabrata Mukherjee
发明人： Terry Cassaday , John Ryan , Paul Thottathil , Purushothaman Kesavan , Satyabrata Mukherjee
IPC分类号： C09D133/14 , C08G18/83
CPC分类号： C09D133/14 , C08F283/006 , C09D175/04 , Y10T428/31576 , C08K3/005 , C08K3/015
摘要： This invention relates to a coating comprising prepolymer and monomers for application onto polyurethane for chemical resistance, abrasion resistance, water proof etc. Usually polyurethane is porous and does not have sufficient stain, abrasion and chemical resistance. The said coatings developed using technology of chemical grafting that involves the use of prepolymers, monomers, catalyst, graft initiator, wetting agents, fillers and other ingredients of the composition. The coating thus obtained when applied on the polyurethane allows obtaining graft polymerization, thereby forming a polymeric film chemically attached to the substrate. The polyurethane substrate is reacted with graft initiator which creates the reaction sites on the substrate via free radical mechanism. This in turn renders the substrate receptive to attachment of monomers/prepolymers forming polymeric film that is chemically bonded to the substrate which has then the desired property in terms of stain resistance, abrasion wear, crock, water, chemical resistance and other properties.
摘要翻译：本发明涉及包含用于耐化学品性，耐磨性，防水性等的聚氨酯的预聚物和单体的涂料。通常聚氨酯是多孔的，并且不具有足够的污渍，耐磨性和耐化学性。使用化学接枝技术开发的所述涂层涉及使用预聚物，单体，催化剂，接枝引发剂，润湿剂，填料和组合物的其它成分。当涂覆在聚氨酯上时由此获得的涂层可以获得接枝聚合，从而形成化学连接到基底上的聚合物膜。聚氨酯基材与接枝引发剂反应，其通过自由基机理在基材上产生反应位点。这反过来使得基材接受形成聚合物膜的单体/预聚物的附着，所述聚合物膜化学键合到基材上，其具有耐污渍性，耐磨损性，耐水性，耐化学性和其它性能方面所需的性能。

56. 发明申请

US20130126199A1 CONTROLLED IMPACT RESCUE TOOL IMPACT ELEMENT 审中-公开
标题翻译：控制冲击工具冲击元件
公开(公告)号：US20130126199A1
公开(公告)日：2013-05-23
申请号：US13303645
申请日：2011-11-23
申请人： Luis Giraldo , Benjamin Dolgin , John Ryan , Michael Millspaugh , Edward Dezelick
发明人： Luis Giraldo , Benjamin Dolgin , John Ryan , Michael Millspaugh , Edward Dezelick
IPC分类号： B25D9/02
CPC分类号： B25D9/02 , A62B3/005 , B25D9/11 , B25D17/02 , B25D2250/051 , B25D2250/211 , B25D2250/361
摘要： An impact element is provided and includes a single body drivable into an external element by force acting on a piston head. The single body includes a head and a shaft having a first end integrally coupled to the head, a second end opposite the first end and a central portion interposed between the first and second ends. The second end of the shaft is operatively connectable with the piston head to define a joint located remotely from the head. The first end of the shaft has a trailing portion with a diameter similar to that of the central portion, a leading portion with a diameter similar to that of the rear end of the head and a taper from the trailing portion to the leading portion.
摘要翻译：提供冲击元件，并且包括通过作用在活塞头上的力可驱动到外部元件中的单个主体。该单体包括头部和轴，该头部具有与头部整体连接的第一端，与第一端相对的第二端和插入在第一和第二端之间的中心部分。轴的第二端可与活塞头可操作地连接，以限定远离头部的接头。轴的第一端具有直径与中心部的直径相似的后部，具有与头部的后端的直径相似的直径的前部以及从后部到前端的锥形。

57. 发明申请

US20130029909A1 TREATMENT OF CANCER 审中-公开
标题翻译：治疗癌症
公开(公告)号：US20130029909A1
公开(公告)日：2013-01-31
申请号：US13479150
申请日：2012-05-23
申请人： John Ryan
发明人： John Ryan
IPC分类号： A61K38/16 , A61P35/04 , A61P35/00
CPC分类号： A61K31/4745 , A61K31/44 , A61K47/61 , C07D491/22 , C07D519/00
摘要： Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.
摘要翻译：提供了涉及包括CDP-拓扑异构酶抑制剂，例如CDP-喜树碱或喜树碱衍生物缀合物例如CRLX101的组合物的方法。

58. 发明授权

US08342069B2 Device and method for controlled breaching of reinforced concrete 有权
公开(公告)号：US08342069B2
公开(公告)日：2013-01-01
申请号：US12906443
申请日：2010-10-18
申请人： Mike Brennan , Brett Goldstein , Luis Giraldo , Rob Wallace , John Ryan , Ed Dezelick , Mike Millspaugh
发明人： Mike Brennan , Brett Goldstein , Luis Giraldo , Rob Wallace , John Ryan , Ed Dezelick , Mike Millspaugh
IPC分类号： B25D9/00
CPC分类号： G01V1/147 , B25D9/06 , B25D9/11 , B25D9/265 , B25D2222/72 , B25D2250/221 , B25D2250/285 , E04G23/08
摘要： A breaching apparatus includes an impactor element and a self-contained energy source. The self-contained energy source enables the impactor element to impact a first surface of a structure. The impactor element is configured to transmit a localized shock wave through the structure upon impact. The self-contained energy source is capable of accelerating the impactor element to a velocity sufficient to induce spalling at a second surface of the structure. Multiple breaching apparatuses can be supported by a frame to facilitate simultaneous or successive breaching of the structure. The breaching apparatus can be used in a method to breach a concrete structure.

59. 发明申请

US20120114658A1 TREATMENT OF CANCER 审中-公开
标题翻译：治疗癌症
公开(公告)号：US20120114658A1
公开(公告)日：2012-05-10
申请号：US13289678
申请日：2011-11-04
申请人： John Ryan , Thomas Schluep
发明人： John Ryan , Thomas Schluep
IPC分类号： A61K39/395 , C08B37/16 , A61P35/00 , A61K31/724
CPC分类号： C07D491/22 , A61K31/44 , A61K31/4745 , A61K31/496 , A61K45/06 , A61K47/55 , A61K47/60 , A61K47/61 , C07D519/00 , A61K2300/00
摘要： Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.
摘要翻译：提供了涉及包括CDP-拓扑异构酶抑制剂，例如CDP-喜树碱或喜树碱衍生物缀合物例如CRLX101的组合物的方法。

60. 发明申请

US20120065161A1 CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY 审中-公开
标题翻译：基于CYCLODEXTRIN的治疗方法的聚合物
公开(公告)号：US20120065161A1
公开(公告)日：2012-03-15
申请号：US13208848
申请日：2011-08-12
申请人： John Ryan
发明人： John Ryan
IPC分类号： A61K31/724 , A61P35/00 , C08B37/16
CPC分类号： A61K31/428 , A61K9/0019 , A61K31/427 , A61K31/724 , A61K45/06 , A61K47/61 , A61K47/6951 , B82Y5/00 , A61K2300/00
摘要： Methods and compositions relating to CDP-epothilone conjugates are described herein.
摘要翻译：本文描述了与CDP-埃坡霉素共轭物相关的方法和组合物。

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