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51. 发明申请

US20080058201A1 Method of Diffusing a Catalyst for Electrochemical Oxygen Reduction 失效
标题翻译：扩散电催化氧化还原催化剂的方法
公开(公告)号：US20080058201A1
公开(公告)日：2008-03-06
申请号：US11837008
申请日：2007-08-10
申请人： John Gordon , Hachiya Toshinori , Shekar Balagopal , Sai Bhavaraju
发明人： John Gordon , Hachiya Toshinori , Shekar Balagopal , Sai Bhavaraju
IPC分类号： B01J21/18 , B01J23/02 , B01J23/04 , B01J23/10 , B01J23/745 , B01J23/75 , B01J23/755
CPC分类号： C25B11/0463 , C23C18/1216 , C23C18/1254 , C23C18/127 , C23C18/1275 , H01M4/8875 , H01M4/9016 , H01M4/96 , H01M8/08 , Y10S502/525 , Y10S516/901
摘要： An improved gas diffusion electrode composed of a perovskite-type oxide dispersed in a mixture of carbon black and a hydrophobic binder polymer. An improved catalyst for use in the electrochemical reduction of oxygen comprising a perovskite-type compound having alpha and beta sites, and having a greater molar ratio of cations at the beta site. A particularly good reduction catalyst is a neodymium calcium manganite. An improved method of dispersing the catalysts with carbon in a reaction layer of the electrode improves performance of the electrode and the oxygen reduction process. This is provided by adding carbon black to an aqueous solution of metal salts before it is heated to a gel and then to a char and then calcined. Optionally, a quantity of the desired oxide catalyst can be premixed with a portion the carbon before adding the carbon to an aqueous solution of the metal salts to be heated. The amount of premixed metal oxide is chosen in conjunction with the amount of metal salts to provide the desired molar ratio after heating and calcining of the aqueous solution.
摘要翻译：改进的气体扩散电极，其由分散在炭黑和疏水性粘合剂聚合物的混合物中的钙钛矿型氧化物组成。用于电化学还原氧的改进的催化剂包括具有α和β位点的钙钛矿型化合物，并且在β位具有更大的阳离子摩尔比。特别好的还原催化剂是钕钙锰矿。将电催化剂用碳分散在电极的反应层中的改进方法提高了电极的性能和氧还原过程。这是通过在金属盐的水溶液加热至凝胶然后加入炭然后煅烧之前将炭黑加入到水溶液中而提供的。任选地，一定量的所需氧化物催化剂可以在将碳添加到待加热的金属盐的水溶液中之前与碳的一部分预混合。联合金属盐的量选择预混合金属氧化物的量，以便在加热和煅烧水溶液之后提供所需的摩尔比。

52. 发明申请

US20070265585A1 Device and method for wound therapy 有权
标题翻译：伤口治疗的装置和方法
公开(公告)号：US20070265585A1
公开(公告)日：2007-11-15
申请号：US11432855
申请日：2006-05-11
申请人： Ashok Joshi , John Gordon , Sai Bhavaraju , Troy Dayton
发明人： Ashok Joshi , John Gordon , Sai Bhavaraju , Troy Dayton
IPC分类号： A61M1/00 , A61H7/00
CPC分类号： A61M1/0088 , A61M1/0015 , A61M1/0025 , A61M1/0052 , A61M1/009 , A61M1/0096 , A61M27/00 , A61M2205/7536
摘要： A wound therapy device is disclosed. The wound therapy device may include a housing for covering at least a portion of a wound and for sealing to a body surface of a patient. The housing may also include a liquid-retention chamber for retaining liquid therein and a vacuum connection for coupling to a vacuum source. The vacuum connection may be in gaseous communication with the liquid-retention chamber. The vacuum connection may be separated from the liquid-retention chamber by a liquid barrier.
摘要翻译：公开了伤口治疗装置。伤口治疗装置可以包括用于覆盖伤口的至少一部分并用于密封到患者身体表面的壳体。壳体还可以包括用于保持液体的液体保持室和用于耦合到真空源的真空连接。真空连接可以与液体保持室气态连通。真空连接可以通过液体屏障与液体保持室分离。

53. 发明申请

US20070166721A1 Fluidic circuits, methods and apparatus for use of whole blood samples in colorimetric assays 审中-公开
标题翻译：在比色测定中使用全血样品的流体回路，方法和装置
公开(公告)号：US20070166721A1
公开(公告)日：2007-07-19
申请号：US10874817
申请日：2004-06-23
申请人： Brigitte Phan , Amethyst Lam , James Coombs , John Gordon
发明人： Brigitte Phan , Amethyst Lam , James Coombs , John Gordon
IPC分类号： C12Q1/68 , C12M3/00
CPC分类号： B01L3/5027 , B01F5/0646 , B01F5/0647 , B01F13/0059 , B01F15/0201 , B01F15/0233 , B01L3/5023 , B01L3/502707 , B01L3/502723 , B01L2200/16 , B01L2300/021 , B01L2300/024 , B01L2300/0803 , B01L2300/0806 , B01L2300/0867 , B01L2400/0409 , G01N21/25 , G01N31/22 , G01N33/528 , G01N33/54366 , G01N35/00069 , G01N2035/00356 , G01N2035/0097
摘要： When the quantification of an analyte is based on a color change detected by a change in the amount of light transmitted or reflected, undiluted samples often saturate the detection range of the assay. Thus, very often, the sample needs to be diluted for reliable quantification. Disclosed are systems and method, including various configurations of fluidic circuits for us on an optical bio-disc, that advantageously allow the use of undiluted and/or whole blood samples for colorimetric assays on optical bio-disc is described.
摘要翻译：当分析物的定量是基于通过透射或反射的光的量的变化检测到的颜色变化时，未稀释的样品通常使测定的检测范围饱和。因此，通常需要稀释样品以进行可靠的定量。公开了系统和方法，其包括在光学生物盘上的用于我们的流体回路的各种配置，其有利地允许在光学生物盘上使用未稀释和/或全血样品进行比色测定。

54. 发明申请

US20070021593A1 High-affinity antagonists of ELR-CXC chemokines 审中-公开
标题翻译： ELR-CXC趋化因子的高亲和力拮抗剂
公开(公告)号：US20070021593A1
公开(公告)日：2007-01-25
申请号：US11434155
申请日：2006-05-16
申请人： John Gordon , Fang Li
发明人： John Gordon , Fang Li
IPC分类号： A61K38/19 , C07K14/52
CPC分类号： C07K14/5421
摘要： The present invention provides novel polypeptide sequences, methods for production thereof and uses thereof for novel ELR—CXC chemokine receptor agonists and antagonists.
摘要翻译：本发明提供新的多肽序列，其制备方法及其用于新型ELR-CXC趋化因子受体激动剂和拮抗剂的用途。

55. 发明授权

US06252112B1 Process for the preparation of an enantiomer of a (1R, 4S) or (1S, 4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene derivative 失效
标题翻译：制备（1R，4S） - 或（1S，4R）-1-氨基-4-（羟甲基）-2-环戊烯衍生物的对映异构体的方法
公开(公告)号：US06252112B1
公开(公告)日：2001-06-26
申请号：US09373857
申请日：1999-08-13
申请人： Christine Bernegger , Eva Maria Urban , Olwen Mary Birch , Kurt Burgdorf , Frank Brux , Kay-Sara Etter , Pierre Bossard , Walter Brieden , Laurent Duc , John Gordon , Colm O'Murchu , Yves Guggisberg
发明人： Christine Bernegger , Eva Maria Urban , Olwen Mary Birch , Kurt Burgdorf , Frank Brux , Kay-Sara Etter , Pierre Bossard , Walter Brieden , Laurent Duc , John Gordon , Colm O'Murchu , Yves Guggisberg
IPC分类号： C07C23118
CPC分类号： C07C231/18 , C07B2200/07 , C07C233/23 , C07C271/24 , C07C2601/10 , C07D209/94 , C12P13/001 , C12P13/02 , C12P17/182
摘要： A novel process for the preparation of (1S, 4R)- or (1R, 4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2 -cyclopentene-1-methanol of the formula is described.
摘要翻译：制备式（1S，4R） - 或（1R，4S）-4-（2-氨基-6-氯-9H-嘌呤-9-基）-2-环戊烯-1-甲醇的新方法描述。

56. 发明授权

US6156893A Process for the preparation of (1S,4R)- or (1R,4S)- 4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol 失效
标题翻译：制备（1S，4R） - 或（1R，4S）-4-（2-氨基-6-氯-9H-嘌呤-9-基）-2-环戊烯-1-甲醇的方法
公开(公告)号：US6156893A
公开(公告)日：2000-12-05
申请号：US73553
申请日：1998-05-06
申请人： Christine Bernegger , Eva Maria Urban , Olwen Mary Birch , Kurt Burgdorf , Frank Brux , Kay-Sara Etter , Pierre Bossard , Walter Brieden , Laurent Duc , John Gordon , Colm O'Murchu , Yves Guggisberg
发明人： Christine Bernegger , Eva Maria Urban , Olwen Mary Birch , Kurt Burgdorf , Frank Brux , Kay-Sara Etter , Pierre Bossard , Walter Brieden , Laurent Duc , John Gordon , Colm O'Murchu , Yves Guggisberg
IPC分类号： C12P41/00 , C07C231/18 , C07C231/20 , C07C233/23 , C07C271/24 , C07D209/94 , C07D233/04 , C07D233/74 , C07D235/02 , C07D237/06 , C07D239/70 , C07D473/40 , C12P13/00 , C12P13/02 , C12P17/18 , C12R1/01 , C12R1/05 , C12R1/06 , C12R1/09 , C12R1/19 , C12R1/38 , C07D487/08 , C07B231/20 , C07B233/23 , C07B233/74
CPC分类号： C07C231/18 , C07C233/23 , C07C271/24 , C07D209/94 , C12P13/001 , C12P13/02 , C12P17/182 , C07B2200/07 , C07C2101/10
摘要： A novel process for the preparation of (1S,4R)- or (1R,4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclo-pentene-1-methanol of the formulae ##STR1## is described. This entails in the first stage (.+-.)-2-aza-bicyclo[2.2.1]hept-5-en-3-one of the formula ##STR2## being acylated to give a (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one derivative of the general formula ##STR3## in which R.sup.1 denotes C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, aryl or aryloxy, the latter being reduced in the second stage to give a cyclopentene derivative of the general formula ##STR4## in which R.sup.1 has the stated meaning, the latter then being converted in the third stage biotechnologically into the (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formula ##STR5## the latter being converted in the fourth stage with N-(2-amino-4,6-dichloro-5-pyrimidinyl)formamide of the formula ##STR6## into the (1S,4R)- or (1R,4S)-4-[(2-amino-6-chloro-5-formamido-4-pyrimidinyl)amino]-2-cyclopentene-1-methanol of the formulae ##STR7## and the latter being cyclized in the fifth stage in a known manner to the final product of the formula I or II.
摘要翻译：制备（1S，4R） - 或（1R，4S）-4-（2-氨基-6-氯-9H-嘌呤-9-基）-2-环戊烯-1-甲醇的新方法描述公式。这需要在酰化的式（+/-） - 2-氮杂 - 双环[2.2.1]庚-5-烯-3-酮中得到（+/-）-2-氮杂双环[2.2 .1]庚-5-烯-3-酮衍生物，其中R 1表示C 1-4 - 烷基，C 1-4 - 烷氧基，芳基或芳氧基，后者在第二阶段中还原，得到环戊烯衍生物（R1，4R） - 或（1S，4R）-1-氨基-4-（羟甲基）-2-环戊烯的化合物，其中R 1具有所述含义，其中后者在第四阶段用式（III）的N-（2-氨基-4,6-二氯-5-嘧啶基）甲酰胺转化成（1S，4R） - 或（1R，4S）-4- 氨基] -2-环戊烯-1-甲醇，后者在第五阶段以已知的方式环化成最终产物，得到式（1）的[（2-氨基-6-氯-5-甲酰氨基-4-嘧啶基）公式I或II。

57. 发明授权

US4951805A Feed hopper with distributor elements 失效
标题翻译：进料斗配有分配器元件
公开(公告)号：US4951805A
公开(公告)日：1990-08-28
申请号：US327248
申请日：1989-03-22
申请人： John Gordon , Erich W. Sodtalbers
发明人： John Gordon , Erich W. Sodtalbers
IPC分类号： B01D33/04
CPC分类号： B01D33/04
摘要： A hopper assembly for uniform distribution of sludge, in which distribution elements on the bottom of the hopper are rotatable about vertical axes to enhance uniformity of distribution of the sludge issuing from the hopper.
摘要翻译：用于均匀分布污泥的料斗组件，其中料斗底部的分配元件可围绕垂直轴线旋转，以增强从料斗发出的污泥的分布均匀性。

58. 发明授权

US4675871A Digital data decoders 失效
标题翻译：数字数据解码器
公开(公告)号：US4675871A
公开(公告)日：1987-06-23
申请号：US659367
申请日：1984-10-10
申请人： John Gordon , Graham King
发明人： John Gordon , Graham King
IPC分类号： H03M13/33 , G06F11/10
CPC分类号： H03M13/33
摘要： A Viterbi decoder is provided with synchronization error detector which detects synchronization errors by monitoring the growth of the path metric associated with a state having itself as a predecessor and to indicate synchronization errors independently of the behavior of metrics associated with other states. The difference between the integral of the selected metric over a certain period of time and the sum of the absolute values of the input encoded data signal is determined and compared to a threshold to indicate whether or not a synchronization error exists.
摘要翻译：维特比解码器具有同步误差检测器，其同步误差检测器通过监视与其本身作为前导相关联的状态相关联的路径度量的增长来检测同步错误，并且独立于与其他状态相关联的度量的行为来指示同步误差。确定在一定时间段内的所选度量的积分与输入编码数据信号的绝对值的和之间的差异，并将其与阈值进行比较，以指示是否存在同步误差。

59. 发明申请

US20160002722A1 METHODS EMPLOYING NON-CODING RNA EXPRESSION ASSAYS 审中-公开
标题翻译：使用非编码RNA表达测定法的方法
公开(公告)号：US20160002722A1
公开(公告)日：2016-01-07
申请号：US14792057
申请日：2015-07-06
申请人： Jacinto ESTIBEIRO , John Gordon , Christopher Robert Hillier , Vincent O'Brien
发明人： Jacinto ESTIBEIRO , John Gordon , Christopher Robert Hillier , Vincent O'Brien
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6876 , C12Q1/6809 , C12Q2600/136 , C12Q2600/142 , C12Q2600/158 , C12Q2600/178 , C12Q2525/207
摘要： There is disclosed a method comprising the steps of: carrying out a plurality of expression assays, each expression assay comprising the steps of: carrying out an intervention on a biological system, measuring an expression profile of non-coding RNAs in the biological system resulting from the intervention, and storing an expression data set derived from the measured expression profile, the said expression assays concerning either or both a plurality of different interventions and a plurality of different biological systems; and analysing the resulting expression data sets to determine correlations between the effect on the expression profile of non-coding RNAs of the respective intervention in groups of two or more expression assays concerning either or both different interventions or different biological systems.
摘要翻译：公开了一种方法，其包括以下步骤：进行多个表达测定，每个表达测定法包括以下步骤：对生物系统进行干预，测量由生物系统产生的生物系统中非编码RNA的表达谱干预，以及存储从测量的表达谱导出的表达数据集，所述表达测定涉及多种不同干预中的一种或两种，以及多种不同的生物系统; 并分析所得到的表达数据集，以确定对于两种或更多种不同介入或不同生物系统之一或两种表达测定的组中相应干预的非编码RNA的表达谱的影响之间的相关性。

60. 发明授权

US09044023B2 System and method for preparing naan bread 有权
标题翻译：制作馒头的系统和方法
公开(公告)号：US09044023B2
公开(公告)日：2015-06-02
申请号：US13040790
申请日：2011-03-04
申请人： Sam Ajmera , John Gordon , Dragan Janus
发明人： Sam Ajmera , John Gordon , Dragan Janus
IPC分类号： A47J39/00 , A21D6/00 , A23C3/00 , A21B1/48 , A23L3/18 , A47J37/04 , A47J37/07 , A23G9/04 , H05B6/78 , A21D8/02 , A21D13/00
CPC分类号： A21B1/48 , A21D8/02 , A21D13/00
摘要： A method and system for preparing naan bread is provided. A conveyor oven is used to bake flattened and pre-shaped naan bread loaves. The conveyor oven uses high temperature gas heat to bake the naan, imparting traditional characteristics such as the slightly smoky or scorched appearance. The oven interior is preferably lined with stone, granite, clay or porcelain to enhance baking and provide traditional flavor.
摘要翻译：提供了一种用于制备馒头的方法和系统。传送炉用于烘烤扁平的和预先形状的荞麦面包面包。传送炉使用高温气体来烘烤na an，赋予传统特性，如微烟或烧焦的外观。烤箱内部最好是用石头，花岗岩，粘土或瓷器衬里，以加强烘烤并提供传统的味道。

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