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51. 发明申请

US20050165488A1 Medical implants and anti-scarring agents 审中-公开
公开(公告)号：US20050165488A1
公开(公告)日：2005-07-28
申请号：US11006912
申请日：2004-12-07
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
IPC分类号： A61B17/11 , A61B17/12 , A61F2/00 , A61F2/02 , A61F2/04 , A61F2/06 , A61F2/28 , A61F2/44 , A61K38/00 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M16/04 , A61M31/00 , A61N1/05 , A62B9/00
CPC分类号： A61L31/16 , A61B17/11 , A61B17/12022 , A61B17/1219 , A61F2250/0067 , A61L2300/404 , A61L2300/406 , A61L2300/416 , A61L2300/426 , A61L2300/432 , A61N1/05
摘要： Implants are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. The agent may be any suitable anti-scarring agent, e.g., a cell cycle inhibitor, and may be used in conjunction with a second pharmaceutical agent, e.g., an antibiotic. Suitable implants include intravascular implants, a vascular graft or wrap implant, an implant for hemodialysis access, an implant that provides an anastomotic connection, ventricular assist implant, a prosthetic heart valve implant, an inferior vena cava filter implant, a peritoneal dialysis catheter implant, a central nervous system shunt, an intraocular lens, an implant for glaucoma drainage, a penile implant, an endotracheal tube, a tracheostomy tube, a gastrointestinal device, and a spinal implant.

52. 发明申请

US20050149175A1 Intravascular devices and fibrosis-inducing agents 审中-公开
公开(公告)号：US20050149175A1
公开(公告)日：2005-07-07
申请号：US11007719
申请日：2004-12-07
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins , Dechi Guan
IPC分类号： A61B17/00 , A61B17/11 , A61B17/12 , A61F2/00 , A61F2/86 , A61F13/00 , A61K38/48 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16 , A61M29/00 , A61M31/00 , A61F2/06
CPC分类号： A61B17/12172 , A61B17/00491 , A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12136 , A61B17/1215 , A61B17/12177 , A61B17/12186 , A61B17/1219 , A61B2017/00004 , A61F2/86 , A61F2250/0067 , A61L31/16 , A61L2300/412
摘要： Intravascular devices (e.g., stents, stent grafts, covered stents, aneurysm coils, embolic agents and drug delivery catheters and balloons) are used in combination with fibrosing agents in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or to promote fibrosis betweent the devices and the host tissues. Compositions and methods are described for use in the treatment of aneurysms and unstable arterial (vulnerable) plaque.

53. 发明申请

US20050142163A1 Medical implants and fibrosis-inducing agents 审中-公开
公开(公告)号：US20050142163A1
公开(公告)日：2005-06-30
申请号：US11001422
申请日：2004-12-01
申请人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
发明人： William Hunter , David Gravett , Philip Toleikis , Arpita Maiti , Pierre Signore , Richard Liggins
IPC分类号： A61B17/11 , A61B17/12 , A61B17/68 , A61C5/00 , A61F2/00 , A61F2/28 , A61F13/00 , A61K31/045 , A61K31/4745 , A61K31/513 , A61K31/525 , A61K31/65 , A61K31/70 , A61K31/7012 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K31/765 , A61K33/14 , A61K33/24 , A61K38/17 , A61K38/18 , A61K38/19 , A61K38/20 , A61K38/24 , A61K38/39 , A61K38/48 , A61K49/00 , A61L27/00 , A61L27/54 , A61L31/00 , A61L31/16
CPC分类号： A61L27/54 , A61B17/11 , A61B17/12022 , A61B17/12099 , A61B17/12109 , A61B17/1214 , A61B17/12168 , A61B17/12186 , A61B17/1219 , A61B17/68 , A61F2250/0067 , A61K38/363 , A61K38/38 , A61K38/39 , A61K38/4833 , A61K45/06 , A61L31/16 , A61L2300/00 , A61L2300/412 , A61L2430/38 , A61K2300/00
摘要： Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the implant and the host tissue.

54. 发明申请

US20050123605A1 Anti-angiogenic compositions and methods of use 有权
公开(公告)号：US20050123605A1
公开(公告)日：2005-06-09
申请号：US10959349
申请日：2004-10-07
申请人： William Hunter , Lindsay Machan , A. Larry-Arsenault , Helen Burt , John Jackson , Stephen Dordunoo
发明人： William Hunter , Lindsay Machan , A. Larry-Arsenault , Helen Burt , John Jackson , Stephen Dordunoo
IPC分类号： C07D305/14 , A61F2/02 , A61F2/06 , A61F2/84 , A61K9/00 , A61K9/16 , A61K9/50 , A61K9/51 , A61K9/70 , A61K31/122 , A61K31/136 , A61K31/175 , A61K31/185 , A61K31/19 , A61K31/203 , A61K31/335 , A61K31/337 , A61K31/519 , A61K31/57 , A61K33/24 , A61K38/00 , A61K38/55 , A61K38/57 , A61K45/00 , A61K45/06 , A61K47/30 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/42 , A61K47/48 , A61L27/34 , A61L27/54 , A61L31/00 , A61L31/08 , A61L31/10 , A61L31/14 , A61L31/16 , A61P1/04 , A61P1/16 , A61P7/04 , A61P9/00 , A61P11/00 , A61P13/02 , A61P27/02 , A61P35/00 , C07K14/81 , C08L23/08 , C08L29/04 , C08L67/04 , A61K9/20 , A61K31/20
CPC分类号： A61K9/14 , A61K9/0019 , A61K9/0048 , A61K9/0051 , A61K9/1635 , A61K9/1641 , A61K9/1647 , A61K9/1658 , A61K9/5031 , A61K9/5146 , A61K9/5153 , A61K9/7007 , A61K31/122 , A61K31/136 , A61K31/165 , A61K31/185 , A61K31/203 , A61K31/335 , A61K31/337 , A61K31/426 , A61K31/427 , A61K31/4745 , A61K31/519 , A61K31/525 , A61K31/555 , A61K31/565 , A61K31/57 , A61K31/702 , A61K33/00 , A61K33/06 , A61K33/24 , A61K33/30 , A61K38/57 , A61K45/06 , A61L31/10 , A61L31/145 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2300/622 , A61L2430/36 , B82Y5/00 , C07C233/64 , C07K14/811 , C08L23/0853 , C08L29/04 , C08L67/04 , C08L2203/02 , C08L2312/00 , Y10S977/773 , Y10S977/915 , C08L23/08 , A61K2300/00 , C08L2666/18 , C08L2666/06 , C08L2666/04
摘要： The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and taxol. Also provided are methods for embolizing blood vessels, and eliminating biliary, urethral, esophageal, and tracheal/bronchial obstructions.

55. 发明申请

US20050107291A1 Compositions and methods for treating or preventing diseases of body passageways 审中-公开
公开(公告)号：US20050107291A1
公开(公告)日：2005-05-19
申请号：US10970705
申请日：2004-10-20
申请人： William Hunter , Lindsay Machan
发明人： William Hunter , Lindsay Machan
IPC分类号： A61K47/30 , A61F2/82 , A61K9/00 , A61K9/10 , A61K9/107 , A61K9/12 , A61K9/16 , A61K9/50 , A61K9/51 , A61K9/70 , A61K31/00 , A61K31/28 , A61K31/335 , A61K31/337 , A61K33/24 , A61K45/00 , A61K45/08 , A61K47/32 , A61K47/34 , A61P1/00 , A61P1/04 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/08 , A61P13/00 , A61P13/02 , A61P13/08 , A61P15/00 , A61P27/02 , A61P31/04 , A61P31/06 , A61P35/00 , A61P43/00 , A61K38/13 , A61K31/4745
CPC分类号： A61K9/0024 , A61K9/10 , A61K9/1075 , A61K9/12 , A61K9/1635 , A61K9/1647 , A61K9/1652 , A61K9/167 , A61K9/5031 , A61K9/5138 , A61K9/5146 , A61K9/5153 , A61K9/5192 , A61K9/70 , A61K9/7007 , A61K31/00 , A61K31/28 , A61K31/335 , A61K31/337 , A61K33/24 , A61K47/34
摘要： The present invention provides methods for treating or preventing diseases associated with body passageways, comprising the step of delivering to an external portion of the body passageway a therapeutic agent. Representative examples of therapeutic agents include anti-angiogenic factors, anti-proliferative agents, anti-inflammatory agents, and antibiotics.

56. 发明申请

US20050101635A1 Compositions and methods for treating or preventing diseases of body passageways 审中-公开
公开(公告)号：US20050101635A1
公开(公告)日：2005-05-12
申请号：US10972307
申请日：2004-10-21
申请人： William Hunter , Lindsay Machan
发明人： William Hunter , Lindsay Machan
IPC分类号： A61K47/30 , A61F2/82 , A61K9/00 , A61K9/10 , A61K9/107 , A61K9/12 , A61K9/16 , A61K9/50 , A61K9/51 , A61K9/70 , A61K31/00 , A61K31/28 , A61K31/335 , A61K31/337 , A61K33/24 , A61K45/00 , A61K45/08 , A61K47/32 , A61K47/34 , A61P1/00 , A61P1/04 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/08 , A61P13/00 , A61P13/02 , A61P13/08 , A61P15/00 , A61P27/02 , A61P31/04 , A61P31/06 , A61P35/00 , A61P43/00 , A61K31/44 , A61K31/4172
CPC分类号： A61K9/0024 , A61K9/10 , A61K9/1075 , A61K9/12 , A61K9/1635 , A61K9/1647 , A61K9/1652 , A61K9/167 , A61K9/5031 , A61K9/5138 , A61K9/5146 , A61K9/5153 , A61K9/5192 , A61K9/70 , A61K9/7007 , A61K31/00 , A61K31/28 , A61K31/335 , A61K31/337 , A61K33/24 , A61K47/34
摘要： The present invention provides methods for treating or preventing diseases associated with body passageways, comprising the step of delivering to an external portion of the body passageway a therapeutic agent. Representative examples of therapeutic agents include anti-angiogenic factors, anti-proliferative agents, anti-inflammatory agents, and antibiotics.

57. 发明授权

US08505625B2 Controlling well operations based on monitored parameters of cement health 有权
标题翻译：基于水泥健康监测参数控制井操作
公开(公告)号：US08505625B2
公开(公告)日：2013-08-13
申请号：US12816749
申请日：2010-06-16
申请人： Kris Ravi , Etienne M. Samson , John L. Maida, Jr. , William Hunter
发明人： Kris Ravi , Etienne M. Samson , John L. Maida, Jr. , William Hunter
IPC分类号： E21B47/12 , E21B49/00
CPC分类号： E21B47/123 , E21B33/14 , G01D5/35303 , G01D5/35364
摘要： A method of controlling a well operation can include monitoring at least one parameter of cement lining a wellbore, the monitoring being performed via at least one optical waveguide, and modifying the well operation in response to the parameter being outside of a predetermined acceptable range. A well monitoring system can include at least one optical waveguide which is used to sense at least one parameter of cement lining a wellbore, an optical interrogation system optically connected to the at least one optical waveguide, and a control system which controls operation of at least one item of well equipment in response to information received from the optical interrogation system.
摘要翻译：控制井操作的方法可以包括监测衬套在井筒中的水泥的至少一个参数，通过至少一个光波导执行监测，以及响应于参数在预定的可接受范围之外修改井操作。良好的监测系统可以包括至少一个光波导，其用于感测衬里在井眼中的水泥的至少一个参数，光学询问系统，光学连接到所述至少一个光波导，以及控制系统，其至少控制至少响应于从光盘询问系统收到的信息，一套井装备件。

58. 发明申请

US20070208134A1 Anti-scarring drug combinations and use thereof 审中-公开
公开(公告)号：US20070208134A1
公开(公告)日：2007-09-06
申请号：US11542185
申请日：2006-10-03
申请人： William Hunter , Philip Toleikis , David Gravett , Daniel Grau , Alexis Borisy , Curtis Keith , Benjamin Auspitz , M. Nichols , Edward Jost-Price , George Serbedzija
发明人： William Hunter , Philip Toleikis , David Gravett , Daniel Grau , Alexis Borisy , Curtis Keith , Benjamin Auspitz , M. Nichols , Edward Jost-Price , George Serbedzija
IPC分类号： A61K47/48
CPC分类号： A61F2/0077 , A61F2250/0067 , A61F2250/0068 , A61K47/6957
摘要： The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic drug combinations, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.

59. 发明申请

US20070130963A1 APPARATUS AND PROCESS FOR VAPORIZING LIQUEFIED NATURAL GAS 审中-公开
标题翻译：用于气化液化天然气的装置和方法
公开(公告)号：US20070130963A1
公开(公告)日：2007-06-14
申请号：US11466207
申请日：2006-08-22
申请人： Denby Morrison , William Hunter , Allen Brooks , Kris Digre , Gregory Koehler
发明人： Denby Morrison , William Hunter , Allen Brooks , Kris Digre , Gregory Koehler
IPC分类号： F17C9/02 , F25D23/12
CPC分类号： F17C9/02 , F17C5/06 , F17C2221/033 , F17C2223/0161 , F17C2223/033 , F17C2223/047 , F17C2225/0123 , F17C2225/035 , F17C2227/0135 , F17C2227/0178 , F17C2227/0185 , F17C2227/032 , F17C2227/0393 , F17C2270/0136
摘要： The invention provides for an apparatus and process for vaporizing liquefied natural gas using groundwater. The invention provides for an apparatus including: a groundwater well; a vaporizer for vaporizing LNG; and an LNG tank. The invention also provides for a process including vaporizing LNG in a vaporizer using groundwater.
摘要翻译：本发明提供了一种使用地下水蒸发液化天然气的装置和方法。本发明提供一种装置，包括：地下水井; 用于蒸发LNG的蒸发器; 和LNG罐。本发明还提供了一种包括使用地下水在蒸发器中蒸发LNG的方法。

60. 发明申请

US20070080238A1 Free flowing water fountain system 审中-公开
标题翻译：自由流水喷泉系统
公开(公告)号：US20070080238A1
公开(公告)日：2007-04-12
申请号：US11243747
申请日：2005-10-06
申请人： William Hunter
发明人： William Hunter
IPC分类号： B05B17/08
CPC分类号： B05B17/08
摘要： My system is designed to provide a continuous flow of water in a vertical motion, without the use of pumps, or electric components. My system uses water volume, mass, weight, and pressure, to create a continuous, vertical flow of water. The pressure is formed, as the water in the hopper, or bowl, flows down through pipes, or hoses, that reduce in diameter, from the starting point. The weight, volume, mass, and gravity of the water being forced down into a reduced hose, or pipe, will create a continuous, vertical flow of water. My invention is not a water fountain, it is a system to provide a fountain with an electrical free, flow of water, in a water fountain. My invention is maintenance free, only have to add water due to evaporation, or chemicals to keep the water clear.
摘要翻译：我的系统设计为在垂直运动中提供连续的水流，不使用泵或电气部件。我的系统使用水量，质量，重量和压力，产生连续，垂直的水流。形成压力，因为料斗或碗中的水通过从起点直径减小的管道或软管向下流动。被迫下降到减少的软管或管道中的水的重量，体积，质量和重力将产生连续的垂直的水流。我的发明不是一个喷泉，它是一个在喷泉中为喷泉提供电动自由，水流的系统。我的发明是免维护的，只能由于蒸发而添加水，或者化学物质保持清水。

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