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51. 发明申请

US20080114408A1 METHOD AND DEVICE FOR SIMULATED EXERCISE 审中-公开
标题翻译：用于模拟运动的方法和装置
公开(公告)号：US20080114408A1
公开(公告)日：2008-05-15
申请号：US11559131
申请日：2006-11-13
申请人： Allan C. Shuros , Joseph M. Pastore , Jeffrey A. Von Arx , Julio C. Spinelli , William J. Linder
发明人： Allan C. Shuros , Joseph M. Pastore , Jeffrey A. Von Arx , Julio C. Spinelli , William J. Linder
IPC分类号： A61N1/37
CPC分类号： A61N1/3627 , A61N1/36542 , A61N1/3682 , A61N1/3684 , A61N1/3688 , A61N1/37205
摘要： A device and method for delivering pacing therapy to the heart in order to improve cardiac function in heart failure and post-MI patients. The pacing therapy is delivered in a manner that mimics the effects of exercise and improves symptoms even in patients who are exercise intolerant. The simulated exercise pacing may be delivered on an intermittent basis in accordance with a defined schedule and/or in response to detected conditions or events.
摘要翻译：用于向心脏输送起搏治疗以改善心力衰竭和MI后患者的心脏功能的装置和方法。起搏疗法以模仿运动效果的方式进行，甚至在运动不耐受的患者中也能改善症状。可以根据定义的时间表和/或响应于检测到的条件或事件以间歇的方式递送模拟锻炼起搏。

52. 发明授权

US07373200B2 System and method for providing tachyarrhythmia therapy by implantable device in presence of system faults 有权
标题翻译：在存在系统故障的情况下通过可植入装置提供快速性心律失常治疗的系统和方法
公开(公告)号：US07373200B2
公开(公告)日：2008-05-13
申请号：US11122970
申请日：2005-05-05
申请人： Scott Stubbs , Conrad L. Sowder , William J. Linder , Lynn S. Elliott , Kenneth P. Hoyme , Hiten J. Doshi
发明人： Scott Stubbs , Conrad L. Sowder , William J. Linder , Lynn S. Elliott , Kenneth P. Hoyme , Hiten J. Doshi
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/3706
摘要： A system and method is disclosed by which an implantable cardiac device may deliver tachyarrhythmia therapy in the event of a system fault. A hardware-based safety core provides the logic circuitry for detecting tachyarrhythmias and delivering shock therapy in the event of a fault which disables operation of the device's primary control circuitry. The safety core defibrillator eliminates common mode failure of the primary control circuits used in the primary defibrillator system. Failures in the primary controller memory or execution will activate the safety core defibrillator.
摘要翻译：公开了一种系统和方法，通过该系统和方法，可植入的心脏装置可在系统故障的情况下递送快速性心律失常治疗。基于硬件的安全核心提供逻辑电路，用于在发生故障的情况下检测快速性心律失常并提供休克治疗，从而禁用设备主要控制电路的操作。安全核心除颤器消除了在主除颤器系统中使用的主要控制电路的共模故障。主控制器存储器或执行中的故障将激活安全核心除颤器。

53. 发明申请

US20080097544A1 DYNAMIC BATTERY MANAGEMENT IN AN IMPLANTABLE DEVICE 有权
标题翻译：可移植设备中的动态电池管理
公开(公告)号：US20080097544A1
公开(公告)日：2008-04-24
申请号：US11551269
申请日：2006-10-20
申请人： Rajesh Krishan Gandhi , William J. Linder , Michael J. Lyden , Nicholas J. Stessman , Jonathan H. Kelly , James Kalgren
发明人： Rajesh Krishan Gandhi , William J. Linder , Michael J. Lyden , Nicholas J. Stessman , Jonathan H. Kelly , James Kalgren
IPC分类号： A61N1/00
CPC分类号： A61N1/378 , A61N1/3627 , A61N1/3708 , A61N1/3975
摘要： One aspect of this disclosure relates to a system for dynamic battery management in implantable medical devices. An embodiment of the system includes two or more devices for measuring battery capacity for an implantable medical device battery. The embodiment also includes a controller connected to the measuring devices. The controller is adapted to combine the measurements from the measuring devices using a weighted average to determine battery capacity consumed. According to various embodiments, at least one of the measuring devices includes a coulometer. At least one of the measuring devices includes a capacity-by-voltage device, according to an embodiment. The system further includes a display in communication with the controller in various embodiments. The display is adapted to provide a depiction of battery longevity in units of time remaining in the life of the implantable medical device battery, according to various embodiments. Other aspects and embodiments are provided herein.
摘要翻译：本公开的一个方面涉及用于可植入医疗装置中的动态电池管理的系统。该系统的实施例包括用于测量可植入医疗装置电池的电池容量的两个或更多个装置。该实施例还包括连接到测量装置的控制器。控制器适于使用加权平均值来组合来自测量装置的测量值，以确定消耗的电池容量。根据各种实施例，至少一个测量装置包括电量计。根据实施例，至少一个测量装置包括逐个电容装置。该系统还包括在各种实施例中与控制器通信的显示器。根据各种实施例，该显示器适于以可植入医疗装置电池的寿命中剩余的时间单位提供电池寿命的描绘。本文提供了其它方面和实施例。

54. 发明授权

US06766201B2 Telemetry apparatus and method for an implantable medical device 有权
标题翻译：用于可植入医疗装置的遥测装置和方法
公开(公告)号：US06766201B2
公开(公告)日：2004-07-20
申请号：US10454013
申请日：2003-06-03
申请人： Jeffrey A. Von Arx , Mark D. Amundson , William R. Mass , Ron Balczewski , William J. Linder
发明人： Jeffrey A. Von Arx , Mark D. Amundson , William R. Mass , Ron Balczewski , William J. Linder
IPC分类号： A61N1372
CPC分类号： A61N1/37223 , A61N1/37229 , A61N1/3727 , Y10S128/901 , Y10S128/903
摘要： An apparatus and method for enabling radio-frequency communications with an implantable medical device utilizing far-field electromagnetic radiation. Such radio-frequency communications can take place over much greater distances than with inductively coupled antennas.
摘要翻译：一种能够利用远场电磁辐射与可植入医疗装置进行射频通信的装置和方法。这种射频通信可以在比电感耦合天线更大的距离上发生。

55. 发明授权

US06505072B1 Implantable electronic stimulator having isolation transformer input to telemetry circuits 有权
标题翻译：具有隔离变压器输入到遥测电路的可植入电子刺激器
公开(公告)号：US06505072B1
公开(公告)日：2003-01-07
申请号：US09714337
申请日：2000-11-16
申请人： William J. Linder , Mark D. Amundson
发明人： William J. Linder , Mark D. Amundson
IPC分类号： A61N108
CPC分类号： A61N1/37211 , A61N1/3752 , Y10S128/903
摘要： An implantable medical device for applying electrical stimulating pulses to body tissue in which the device includes a hermetically sealed metal housing that contains the stimulating pulse delivery circuitry as well as a telemetry transmitter and telemetry receiver and where the metal housing serves as a return electrode. An isolation transformer is operatively coupled between an antenna/coil used to receive and transmit information from and to an external programmer device and the telemetry receiver and telemetry transmitter within the implanted device. The isolation transformer effectively precludes high voltage stimulating pulses from causing damage to the telemetry circuit components.
摘要翻译：一种用于向身体组织施加电刺激脉冲的可植入医疗装置，其中所述装置包括密封金属壳体，所述金属壳体包含刺激脉冲输送电路以及遥测发射器和遥测接收器，并且金属壳体用作返回电极。隔离变压器可操作地耦合在用于从外部编程器装置接收和发送信息的天线/线圈与植入装置内的遥测接收器和遥测发射器之间。隔离变压器有效地排除了高压刺激脉冲对遥测电路部件的损坏。

56. 发明授权

US06456256B1 Circumferential antenna for an implantable medical device 有权
标题翻译：可植入医疗器械的圆周天线
公开(公告)号：US06456256B1
公开(公告)日：2002-09-24
申请号：US09921653
申请日：2001-08-03
申请人： Mark D. Amundson , Jeffrey A. Von Arx , William J. Linder , Prashant Rawat , William R. Mass
发明人： Mark D. Amundson , Jeffrey A. Von Arx , William J. Linder , Prashant Rawat , William R. Mass
IPC分类号： H01Q140
CPC分类号： H01Q1/22 , A61N1/37229 , Y10S128/903
摘要： An apparatus and method for enabling far-field radio-frequency communications with an implantable medical device in which an antenna is embedded within a dielectric around the periphery of the device. Such a circumferential antenna saves space while still permitting far-field telemetry over a desired range of frequencies.
摘要翻译：一种用于实现与可植入医疗装置的远场射频通信的装置和方法，其中天线嵌入设备外围的电介质周围。这种周向天线节省了空间，同时仍然允许在期望的频率范围上进行远场遥测。

57. 发明授权

US06198123B1 Shielded integrated circuit capacitor connected to a lateral transistor 失效
标题翻译：屏蔽集成电路电容器
公开(公告)号：US06198123B1
公开(公告)日：2001-03-06
申请号：US08924456
申请日：1997-08-29
申请人： William J. Linder , Robert S. Harguth
发明人： William J. Linder , Robert S. Harguth
IPC分类号： H01G428
CPC分类号： H01L28/40
摘要： An integrated circuit (IC) capacitor offers reduced sensitivity to parasitic capacitance, reduced-size, and increased noise immunity, such as for use in digital-to-analog converters (DACs), analog-to-digital converters (ADCs), switched-capacitor filters, and other IC circuits. The capacitor includes a first polysilicon layer, a superjacent second polysilicon layer separated from the first polysilicon layer by an insulator, and an overlying metal layer separated from the second polysilicon layer by an insulator. The metal layer provides a shield that is connected to a known voltage, or to the first polysilicon layer. When connected to the first polysilicon layer, the overlying metal layer also provides additional parallel capacitance, thereby reducing the integrated circuit area of the capacitor. In one example, the overlying metal layer is a second metal layer that is also used, together with a first metal layer, for interconnecting IC components.
摘要翻译：集成电路（IC）电容器对寄生电容的灵敏度降低，尺寸减小，抗噪声能力增强，例如用于数/模转换器（DAC），模/数转换器（ADC）电容滤波器和其他IC电路。电容器包括第一多晶硅层，通过绝缘体与第一多晶硅层分离的相邻的第二多晶硅层，以及通过绝缘体与第二多晶硅层分离的上覆金属层。金属层提供连接到已知电压的屏蔽，或者连接到第一多晶硅层。当连接到第一多晶硅层时，上覆金属层还提供额外的并联电容，从而减小电容器的集成电路面积。在一个示例中，上覆金属层是第二金属层，其也与第一金属层一起用于互连IC部件。

58. 发明授权

US5959371A Power management system for an implantable device 有权
公开(公告)号：US5959371A
公开(公告)日：1999-09-28
申请号：US190971
申请日：1998-11-12
申请人： Michael W. Dooley , Keith R. Maile , William J. Linder
发明人： Michael W. Dooley , Keith R. Maile , William J. Linder
IPC分类号： A61N1/37 , A61N1/378 , A61N1/39 , H01H35/00
CPC分类号： A61N1/378 , A61N1/3708 , A61N1/3937 , A61N1/3975 , A61N1/3981 , Y10T307/826 , Y10T307/839 , Y10T307/858
摘要： A power management system for an implantable device is disclosed. One application is an implantable cardioverter/defibrillator. Charging circuits for implantable cardioverter/defibrillators require relatively large currents from the power supply. The present power management system provides extended device operation and reduced charge cycle time. The present system monitors both current and voltage drawn from the power supply to prevent a loss of system voltage. Elective replacement indication is performed using charging information provided by the present power management system.

59. 发明授权

US5699014A Linear amplifier 失效
标题翻译：线性放大器
公开(公告)号：US5699014A
公开(公告)日：1997-12-16
申请号：US627403
申请日：1996-04-04
申请人： Paul A. Haefner , William J. Linder
发明人： Paul A. Haefner , William J. Linder
IPC分类号： H03F1/32 , H03F3/45
CPC分类号： H03F1/3211 , H03F1/3205 , H03F2200/162 , H03F2200/372
摘要： A low-noise, low-power complementary metal-oxide-semiconductor (CMOS) integrated circuit common source differential amplifier is disclosed which is capable of amplifying low amplitude cardiac signals such as those produced by atrial depolarization of the heart. The amplifier has a pair of large area p-channel input field-effect transistors (FETs) biased in weak inversion. The amplifier also has active load FETs biased in the nonsaturation (linear) region by means of a varying gate terminal voltage applied by a dynamic bias circuit. The gate terminal voltage is varied to match the temperature dependence of the output conductance of the load FETs to the temperature dependence of the transconductance of the input FETs. The gate terminal voltage also sets a dc bias point which uses the nonlinearity in the load FET output conductance to cancel nonlinearity in the input FET transconductance.
摘要翻译：公开了一种低噪声，低功率互补金属氧化物半导体（CMOS）集成电路公共源差分放大器，其能够放大低振幅心脏信号，例如通过心脏去极化产生的心脏信号。放大器具有一对在弱反相中偏置的大面积p沟道输入场效应晶体管（FET）。放大器还通过由动态偏置电路施加的变化的栅极端子电压而在非饱和（线性）区域中偏置有有源负载FET。栅极端子电压变化以匹配负载FET的输出电导的温度依赖性与输入FET的跨导的温度依赖性。栅极端子电压还设置直流偏置点，其使用负载FET输出电导中的非线性来消除输入FET跨导中的非线性。

60. 发明授权

US4768019A Analog-to-digital converter 失效
标题翻译：模数转换器
公开(公告)号：US4768019A
公开(公告)日：1988-08-30
申请号：US101109
申请日：1987-09-25
申请人： William J. Linder
发明人： William J. Linder
IPC分类号： H03M1/08 , H03M1/00 , H03M1/50
CPC分类号： H03M1/52 , H03M1/123
摘要： An integrating analog-to-digital converter having an operational amplifier serving as an integrator and as a comparator.

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