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51. 发明授权

US07616995B2 Variable recharge determination for an implantable medical device and method therefore 有权
标题翻译：因此，可植入式医疗装置的可变补充确定和方法
公开(公告)号：US07616995B2
公开(公告)日：2009-11-10
申请号：US11414156
申请日：2006-04-28
申请人： Carl D. Wahlstrand , Robert M. Skime , Erik R. Scott , Craig L. Schmidt
发明人： Carl D. Wahlstrand , Robert M. Skime , Erik R. Scott , Craig L. Schmidt
IPC分类号： A61N1/378
CPC分类号： A61N1/3787
摘要： Implantable medical device adapted to provide a therapeutic output to a patient. A therapy module, operatively coupled to a battery, is adapted to provide the therapeutic output. A control circuit provides an action indicative of recharging the battery when the voltage of the battery reaches a recharge voltage wherein the recharge voltage is varied as the battery ages. Also a method of providing a therapeutic output to a patient using an implantable medical device having a battery having a voltage. An action indicative of recharging the battery is provided when the voltage of the battery reaches a recharge voltage. The recharge voltage is varied as the battery ages.
摘要翻译：适于向患者提供治疗输出的可植入医疗装置。可操作地耦合到电池的治疗模块适于提供治疗输出。当电池的电压达到再充电电压时，控制电路提供指示对电池再充电的动作，其中充电电压随电池老化而变化。还有一种使用具有电压的电池的可植入医疗装置向患者提供治疗输出的方法。当电池的电压达到充电电压时，提供指示对电池再充电的动作。充电电压随电池老化而变化。

52. 发明申请

US20090234420A1 IMPLANTABLE NEUROSTIMULATOR DEVICE 失效
标题翻译：可植入神经细胞装置
公开(公告)号：US20090234420A1
公开(公告)日：2009-09-17
申请号：US12476023
申请日：2009-06-01
申请人： Carl D. Wahlstrand , Robert M. Skime
发明人： Carl D. Wahlstrand , Robert M. Skime
IPC分类号： A61N1/34
CPC分类号： A61N1/0504 , A61N1/0456 , A61N1/0476 , A61N1/0492 , A61N1/0502 , A61N1/36071 , A61N1/3756
摘要： The disclosure describes an implantable neurostimulator device for delivery of neurostimulation to treat head, neck, or facial pain or tension, including pain or tension caused by occipital neuralgia. The device may be a neurostimulation device having a miniaturized housing with a low profile that permits subcutaneous implantation at a stimulation site directly adjacent a neuralgic region at the back of the neck of a patient. For example, the device may be subcutaneously implanted at the back of the neck of a patient to relieve symptoms of occipital neuralgia.
摘要翻译：本公开描述了用于递送神经刺激以治疗头部，颈部或面部疼痛或张力的可植入神经刺激器装置，包括由枕骨神经痛引起的疼痛或张力。该装置可以是具有小型化的壳体的神经刺激装置，其具有允许在紧邻患者颈部后方的神经痛区域的刺激部位皮下植入。例如，该装置可以皮下植入患者颈部的后部以减轻枕骨神经痛的症状。

53. 发明授权

US07529586B2 Concavity of an implantable medical device 有权
标题翻译：可植入医疗器械的凹陷
公开(公告)号：US07529586B2
公开(公告)日：2009-05-05
申请号：US10731867
申请日：2003-12-09
申请人： Carl D. Wahlstrand , Darren A. Janzig , Ruchika Singhal , Robert M. Skime , Erik R. Scott , James E. Randall
发明人： Carl D. Wahlstrand , Darren A. Janzig , Ruchika Singhal , Robert M. Skime , Erik R. Scott , James E. Randall
IPC分类号： A61N1/36
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： At least one surface of an implantable medical device is concave along at least one axis such that it substantially conforms to a surface within a patient, such as the cranium, when it is implanted on that surface. In some embodiments, the surface of the implantable medical device substantially conforms to an arc with a radius that is between 4.5 and 9.5 centimeters, and is preferably approximately equal to 7 centimeters. In some embodiments, the implantable medical device comprises a plurality of interconnected modules, and an overmold that at least partially encapsulates each of the modules. In such embodiments, at least one surface of the overmold is concave along at least one axis. Further, each of the modules of such an implantable medical device may comprise a housing, and at least one surface of at least one of the housings may be concave along at least one axis.
摘要翻译：可植入医疗装置的至少一个表面沿着至少一个轴线是凹形的，使得当植入在该表面上时，其基本上符合患者（例如颅骨）内的表面。在一些实施例中，可植入医疗装置的表面基本上符合半径在4.5和9.5厘米之间的弧度，并且优选地大约等于7厘米。在一些实施例中，可植入医疗装置包括多个互连的模块，以及至少部分地封装每个模块的包覆模制。在这样的实施例中，包覆模制体的至少一个表面沿着至少一个轴线是凹形的。此外，这种可植入医疗装置的每个模块可以包括壳体，并且至少一个壳体的至少一个表面沿着至少一个轴线可以是凹形的。

54. 发明授权

US09084901B2 Cranial implant 有权
标题翻译：颅内植入
公开(公告)号：US09084901B2
公开(公告)日：2015-07-21
申请号：US11413618
申请日：2006-04-28
申请人： Carl D. Wahlstrand
发明人： Carl D. Wahlstrand
IPC分类号： A61N1/375 , A61N1/05 , A61B5/0478 , A61B5/00 , A61N1/36
CPC分类号： A61B5/0478 , A61B5/6868 , A61N1/0529 , A61N1/0534 , A61N1/0539 , A61N1/3605 , A61N1/3606 , A61N1/36082 , A61N1/36135 , A61N1/375
摘要： Implantable medical devices (IMD) configured for implantation within a recess formed in a cranium of a patient, as well as associated methods, are described. In some embodiments, the IMD includes a top external surface and another adjacent external surface, e.g., a side surface, which are oriented with respect to each other to define an acute angle. A connection module for an electrical lead or catheter may be included on the top external surface. Embodiments of the invention may facilitate implantation of an IMD within a recess formed in the cranium of a patient at a location remote to an incision made in the scalp of the patient.
摘要翻译：描述了被配置用于植入在形成在患者的颅骨中的凹部内的植入式医疗装置（IMD）以及相关联的方法。在一些实施例中，IMD包括顶部外表面和相对于彼此定向以限定锐角的另一相邻外表面，例如侧表面。用于电引线或导管的连接模块可以包括在顶部外表面上。本发明的实施例可以有助于将IMD植入位于患者头颅内的凹陷部位于远离患者头皮的切口的位置。

55. 发明授权

US08934973B2 Hub for implantable medical leads 有权
标题翻译：用于可植入医疗线的集线器
公开(公告)号：US08934973B2
公开(公告)日：2015-01-13
申请号：US13376141
申请日：2010-06-21
申请人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar , Lisa M. Johanek
发明人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar , Lisa M. Johanek
IPC分类号： A61N1/05 , H04L12/18 , H04L12/58 , H04W72/00 , H04W72/12
CPC分类号： H04L12/189 , A61N1/3752 , H01R13/5224 , H01R24/58 , H01R31/02 , H01R2107/00 , H01R2201/12 , H04L51/38 , H04W72/005 , H04W72/1273 , H04W72/1289
摘要： A hub (200) includes a first lead receptacle having a plurality of contacts (280) for electrically coupling a lead to an implantable electrical device. The hub further contains a second lead receptacle having a plurality of contacts for electrically coupling a lead to the implantable electrical device. At least one of the plurality of contacts of the first receptacle is a contact of the second receptacle. Such a configuration may allow for the overall size of the hub to be reduced relative to a hub where each discrete contact of the hub corresponds to a discrete contact or electrical channel of the implantable electrical device.
摘要翻译：轮毂（200）包括具有用于将引线电耦合到可植入电气装置的多个触点（280）的第一引线插座。轮毂还包括具有用于将引线电耦合到可植入电气装置的多个触点的第二引线插座。第一容器的多个触点中的至少一个是第二插座的触点。这种构造可以允许毂的总体尺寸相对于轮毂减小，其中毂的每个离散接触对应于可植入电气设备的离散接触或电通道。

56. 发明授权

US08929993B2 Electrode arrangements for suborbital foramen medical lead 有权
标题翻译：用于亚轨道孔的医疗铅的电极安排
公开(公告)号：US08929993B2
公开(公告)日：2015-01-06
申请号：US13376152
申请日：2010-06-21
申请人： Carl D. Wahlstrand , Dale F. Seeley , Lisa M. Johanek , John E. Kast , Phillip C. Falkner , Louis P. Vera-Portocarrero
发明人： Carl D. Wahlstrand , Dale F. Seeley , Lisa M. Johanek , John E. Kast , Phillip C. Falkner , Louis P. Vera-Portocarrero
IPC分类号： A61N1/05
CPC分类号： A61N1/0551
摘要： A medical lead includes a plurality of electrodes on an annular distal end portion of the lead. The electrodes may be arranged along a circle concentric with the center of a void defined by the annular portion. The annular medical lead design is well suited for application of electrical signal therapy to the suborbital nerve at its point of exit from the inferior orbital foramen in the skull.
摘要翻译：医疗引线包括在引线的环形远端部分上的多个电极。电极可以沿与由环形部分限定的空隙的中心同心的圆排布置。环形医疗引线设计非常适合于在颅骨下游轨道孔出口点处向眶下神经施加电信号治疗。

57. 发明授权

US08538549B2 Programming interface for stimulation therapy 有权
标题翻译：刺激治疗的编程界面
公开(公告)号：US08538549B2
公开(公告)日：2013-09-17
申请号：US13592918
申请日：2012-08-23
申请人： Steven M. Goetz , Richard T. Stone , Warren W. Ball , Carl D. Wahlstrand
发明人： Steven M. Goetz , Richard T. Stone , Warren W. Ball , Carl D. Wahlstrand
IPC分类号： A61N1/08
CPC分类号： A61N1/0534 , A61N1/36071 , A61N1/36157 , A61N1/36185 , A61N1/37247
摘要： The disclosure is directed to programming implantable stimulators to deliver stimulation energy via one or more implantable leads having complex electrode array geometries. The disclosure also contemplates guided programming to select electrode combinations and parameter values to support efficacy. The techniques may be applied to a programming interface associated with a clinician programmer, a patient programmer, or both. A user interface permits a user to view electrodes from different perspectives relative to the lead. For example, the user interface provides a side view of a lead and a cross-sectional view of the lead. The user interface may include an axial control medium to select and/or view electrodes at different axial positions along the length of a lead, and a rotational control medium to select and/or view electrodes at different angular positions around a circumference of the lead.
摘要翻译：本公开涉及编程可植入刺激器以通过具有复杂电极阵列几何形状的一个或多个可植入引线输送刺激能量。本公开还考虑了引导编程以选择电极组合和参数值以支持功效。这些技术可以应用于与临床医生程序员，患者程序员或两者相关联的编程接口。用户界面允许用户从相对于铅的不同角度来观察电极。例如，用户界面提供引线的侧视图和引线的横截面图。用户界面可以包括轴向控制介质，用于选择和/或查看沿引线长度的不同轴向位置处的电极;以及旋转控制介质，用于选择和/或查看围绕引线圆周的不同角位置处的电极。

58. 发明授权

US08509920B2 Electrode arrangements for medical lead 有权
标题翻译：医用铅电极装置
公开(公告)号：US08509920B2
公开(公告)日：2013-08-13
申请号：US13376133
申请日：2010-06-21
申请人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar
发明人： Carl D. Wahlstrand , Dale F. Seeley , Gabriela C. Molnar
IPC分类号： A61N1/04
CPC分类号： A61N1/0551 , A61N1/0556
摘要： An implantable medical lead includes a lead body having a proximal portion having a longitudinal axis and an arcuate distal body portion extending in the direction of the longitudinal axis. The arcuate distal body portion has a concave surface. The lead includes a plurality of elongate electrodes disposed at the arcuate distal end portion of the lead body along the concave surface. The electrodes extend substantially parallel to the longitudinal axis of the lead body.
摘要翻译：可植入医疗引线包括具有纵向轴线的近端部分和沿着纵向轴线方向延伸的弓形远侧主体部分的引线主体。弓形的远侧主体部分具有凹面。引线包括沿着凹面设置在引线主体的弓形远端部分处的多个细长电极。电极基本上平行于引线主体的纵向轴线延伸。

59. 发明授权

US08204607B2 Implantable medical lead 有权
标题翻译：可植入医用铅
公开(公告)号：US08204607B2
公开(公告)日：2012-06-19
申请号：US11450148
申请日：2006-06-09
申请人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Richard T. Stone
发明人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Richard T. Stone
IPC分类号： A61N1/36
CPC分类号： A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/37211
摘要： The disclosure describes an implantable medical lead for delivering stimulation to a patient. Electrodes may be located on two or more surfaces of the lead to, for example, selectively deliver stimulation to one or more tissue layers within the patient. The lead may be implanted within or between intra-dermal, deep dermal, or subcutaneous tissue layers, and may be used to, for example, deliver peripheral nerve field stimulation to treat pain experienced by the patient at the site at which the lead is implanted. The lead may comprise a paddle lead or a multiple level lead, e.g., a lead having a plurality of flat or paddle shaped lead bodies arranged in substantially parallel planes. Further, the lead may include fixation structures on the distal end, proximal end, or both ends to prevent migration.
摘要翻译：本公开描述了用于将刺激递送给患者的可植入医疗引线。电极可以位于引线的两个或更多个表面上，以例如选择性地将刺激递送到患者体内的一个或多个组织层。铅可以植入在真皮内，深层皮肤或皮下组织层之内或之间，并且可以用于例如递送周围神经域刺激，以治疗患者在植入铅的部位所经历的疼痛。引线可以包括桨引线或多级引线，例如具有布置在基本上平行的平面中的多个扁平或桨状引线的引线。此外，引线可以包括远端，近端或两端的固定结构，以防止迁移。

60. 发明授权

US08121694B2 Therapy control based on a patient movement state 有权
标题翻译：基于患者运动状态的治疗控制
公开(公告)号：US08121694B2
公开(公告)日：2012-02-21
申请号：US12237799
申请日：2008-09-25
申请人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
发明人： Gregory F. Molnar , Steven S. Gill , Keith A. Miesel , Mark S. Lent , Timothy J. Denison , Eric J. Panken , Carl D. Wahlstrand , Jonathan C. Werder
IPC分类号： A61N1/18
CPC分类号： A61B5/04014 , A61B5/0006 , A61B5/4082 , A61B5/6814 , A61N1/36003 , A61N1/36014 , A61N1/36025 , A61N1/36067 , A61N1/36082
摘要： A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.
摘要翻译：基于诸如脑电图（EEG）信号的脑信号检测患者的运动状态。在一些示例中，可以检测指示患者的预期运动的患者的脑的背侧前额叶皮层内的脑信号，以便检测运动状态。运动状态可以包括指示患者打算启动运动，启动运动，尝试启动运动或实际运动的脑状态。在一些示例中，在检测到运动状态时，将运动障碍治疗递送给患者。在一些示例中，在检测到患者不再处于运动状态或患者已成功启动运动时，治疗递送被停用。此外，在一些示例中，可以基于来自运动传感器的信号来确认基于脑信号检测到的运动状态。

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