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51. 发明授权

US07810677B2 One-way valve and apparatus and method of using the valve 有权
标题翻译：单向阀及其使用方法及阀门
公开(公告)号：US07810677B2
公开(公告)日：2010-10-12
申请号：US11650102
申请日：2007-01-05
申请人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B65D37/00
CPC分类号： B67D1/108 , B05B11/00444 , B65B39/004 , B65D51/002 , B65D51/1616 , B67D1/0004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/0801 , B67D1/10 , B67D1/1279 , B67D3/0067 , B67D3/04 , B67D2001/0827 , F04B53/1037
摘要： A flexible pouch defining a variable volume storage chamber and one-way valve assembly for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom in cooperation with a pump, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The one-way valve includes a valve seat and elastic valve cover portion overlying the valve seat forming an interference fit therewith defining a normally-closed seam therebetween. The valve portion is movable radially between (i) a normally closed position with the valve portion engaging the valve seat, and (ii) an open position with at least a segment of the valve portion spaced radially away from the valve seat to allow substance from the storage chamber through the valve opening. The one-way valve maintains substance remaining in the variable-volume storage chamber in an aseptic condition sealed with respect to the ambient atmosphere.
摘要翻译：柔性袋，其限定可变体积存储室和用于无菌存储物质的单向阀组件，与泵协作地分配多个储存物质的部分，并将残留在袋中的物质保持在相对于环境气氛。单向阀包括阀座和覆盖阀座的弹性阀盖部分，形成过盈配合，从而限定了它们之间的常闭接缝。阀部分可以在（i）常闭位置之间径向移动，阀部分接合阀座，和（ii）打开位置，其中阀部分的至少一段与阀座径向间隔开，从而允许物质从储存室通过阀门开口。单向阀在相对于环境大气密封的无菌状态下保持残留在可变容积储存室中的物质。

52. 发明授权

US07322491B2 Method of using one-way valve and related apparatus 有权
标题翻译：使用单向阀及相关设备的方法
公开(公告)号：US07322491B2
公开(公告)日：2008-01-29
申请号：US11295251
申请日：2005-12-05
申请人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B67B7/00
CPC分类号： B67D1/0004 , B65B39/004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/10 , B67D1/108 , B67D1/1279 , B67D3/04 , B67D2001/0827 , F04B43/1238 , F04B53/1037 , Y10T137/7761
摘要： An apparatus has a valve body defining a first passageway, a valve seat, and a flow aperture extending through the valve body and coupled in fluid communication with the first passageway. A valve cover of the apparatus is formed of an elastic material and includes a cover base mounted on the valve body and fixedly secured against movement relative thereto, and a valve portion overlying the valve seat. The valve portion defines a predetermined radial thickness and forms an interference fit with the valve seat. The valve portion and the valve seat define a normally closed, axially-extending valve opening therebetween. The valve portion is movable between a normally closed position with the valve portion engaging the valve seat, and an open position with at least a segment of the valve portion spaced away from the valve seat to connect the valve opening in fluid communication with the flow aperture to thereby allow the passage of fluid from the flow aperture through the valve opening. A hermetically sealed variable-volume storage chamber stores therein multiple portions of the fluid and is connectible in fluid communication with the one-way valve assembly. A pump is coupled between the variable-volume storage chamber and the one-way valve assembly, and is configured to pump discrete portions of fluid from the variable-volume storage chamber, through the flow aperture, and through the valve opening to dispense the portions of fluid through the valve assembly.
摘要翻译：一种装置具有限定第一通道，阀座和延伸穿过阀体并与第一通道流体连通地联接的流动孔的阀体。该装置的阀盖由弹性材料形成，并且包括安装在阀体上的盖基座，并且固定地抵靠其相对移动，以及覆盖在阀座上的阀部分。阀部分限定预定的径向厚度并与阀座形成过盈配合。阀部分和阀座限定了其间的常闭的，轴向延伸的阀开口。阀部分可以在与阀座接合的阀部分的常闭位置和打开位置之间移动，打开位置具有与阀座间隔开的阀部分的至少一段，以连接与开口流体连通的阀开口从而允许流体从流动孔通过阀开口。气密密封的可变容积储存室在其中存储有多个流体部分，并可与单向阀组件流体连通。泵连接在可变容积存储室和单向阀组件之间，并且构造成从可变容积储存室通过流动孔泵送离散的流体部分，并且通过阀开口分配部分的流体通过阀组件。

53. 发明申请

US20070283666A1 Ready to drink container with nipple and needle penetrable and laser resealable portion, and related method 有权
标题翻译：准备饮用容器，乳头和针头可穿透，激光可再密封部分，以及相关方法
公开(公告)号：US20070283666A1
公开(公告)日：2007-12-13
申请号：US11786206
申请日：2007-04-10
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willley
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willley
IPC分类号： B65B55/02
CPC分类号： A61J11/0005 , A61J1/1406 , A61J9/003 , A61J11/04 , B65D51/002
摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.
摘要翻译：提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

54. 发明授权

US08739838B2 Adjustable filling and sealing method and apparatus therefor 有权
标题翻译：可调填充和密封方法及其设备
公开(公告)号：US08739838B2
公开(公告)日：2014-06-03
申请号：US13352235
申请日：2012-01-17
申请人： Daniel Py , Benoit Adamo , John Guthy
发明人： Daniel Py , Benoit Adamo , John Guthy
IPC分类号： B65B1/04 , G01N23/00 , B65B51/10 , A61M5/178 , B29C65/00 , A61L2/10
CPC分类号： B65B3/006 , A61L2/10 , A61M5/1782 , B29C66/80 , B65B3/003 , B65B43/00 , B65B51/00 , Y10T29/49716
摘要： An assembly includes a support and drive assembly, a first structure and a second structure. The first structure is in operable communication with and supported by the support and drive assembly. The first structure includes at least one filling or needle assembly and is adjustable to receive a plurality of filling or needle assemblies. The second structure is supported by the support and drive assembly. The second structure includes at least one seal assembly and is adjustable to receive a plurality of seal assemblies. A method includes determining a number of containers or vials that are to be filled concurrently and adjusting an assembly to include at least one filling or needle assembly and at least one seal assembly. A number of the filling or needle assemblies and the seal assemblies equals the number of containers or vials.
摘要翻译：组件包括支撑和驱动组件，第一结构和第二结构。第一结构与支撑和驱动组件可操作地连通并由其支撑。第一结构包括至少一个填充物或针头组件，并且可调节以容纳多个填充物或针头组件。第二个结构由支撑和驱动组件支撑。第二结构包括至少一个密封组件，并且可调节以接收多个密封组件。一种方法包括确定要同时填充的多个容器或小瓶，并且调整组件以包括至少一个填充物或针组件和至少一个密封组件。许多填充物或针组件和密封组件等于容器或小瓶的数量。

55. 发明申请

US20120076883A1 Sterile De-Molding Apparatus and Method 有权
标题翻译：无菌脱模装置及方法
公开(公告)号：US20120076883A1
公开(公告)日：2012-03-29
申请号：US13311616
申请日：2011-12-06
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Giovanni Rodriguez
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Giovanni Rodriguez
IPC分类号： B29C45/18
CPC分类号： B29C45/1701 , B29C37/0007 , B29C45/006 , B29C45/1753 , B29C45/40 , B29C45/42 , B29C2045/1797 , B29C2791/005
摘要： At least one of first and second mold portions defines a mold cavity to receive molten plastic and form therefrom at least one molded part, and is movable relative to the other between (i) a closed position for sealing the mold cavity or cavities and molding at least one part therein, and (ii) an open position defining a fluid passageway between the mold portions and permitting the passage of a fluid sterilant therein. A fluid sterilant source is connectable in fluid communication with the fluid passageway for introducing the sterilant therein in the open position, contacting with the sterilant the surfaces of the first and second mold portions forming the fluid passageway and located adjacent to the at least one mold cavity, but not contacting an interior surface of a molded part within the mold cavity, to sterilize the exposed mold surfaces and thereby prevent contamination of the molded part.
摘要翻译：第一和第二模具部分中的至少一个限定了模腔以接收熔融塑料并从其形成至少一个模制部件，并且可以在（i）用于密封模腔或空腔的闭合位置和相对于另一模制部件其中至少一部分，以及（ii）在模具部分之间限定流体通道并允许其中的流体灭菌剂通过的打开位置。流体灭菌剂源可连接到流体通道，用于将灭菌剂在其中引入打开位置，与杀菌剂接触，形成第一和第二模具部分的形成流体通道的表面并且邻近于至少一个模腔但是不与模腔内的模制部件的内表面接触，对暴露的模具表面进行消毒，从而防止模制部件的污染。

56. 发明申请

US20100316774A1 READY TO DRINK CONTAINER WITH NIPPLE AND NEEDLE PENETRABLE AND LASER RESEALABLE PORTION, AND RELATED METHOD 失效
标题翻译：准备饮用容器和针头和可激光部分及相关方法
公开(公告)号：US20100316774A1
公开(公告)日：2010-12-16
申请号：US12861354
申请日：2010-08-23
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willey
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willey
IPC分类号： A61J9/00 , B65B55/08
CPC分类号： A61J11/0005 , A61J1/1406 , A61J9/003 , A61J11/04 , B65D51/002
摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.
摘要翻译：提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

57. 发明授权

US07850051B2 Apparatus having one-way valve 有权
标题翻译：具有单向阀的装置
公开(公告)号：US07850051B2
公开(公告)日：2010-12-14
申请号：US12021115
申请日：2008-01-28
申请人： Daniel Py , Julian V. Chan , Benoit Adamo
发明人： Daniel Py , Julian V. Chan , Benoit Adamo
IPC分类号： B65D37/00
CPC分类号： B67D1/0004 , B65B39/004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/10 , B67D1/108 , B67D1/1279 , B67D3/04 , B67D2001/0827 , F04B43/1238 , F04B53/1037 , Y10T137/7761
摘要： A device including a valve body defining a first passageway, a valve seat, and a flow aperture extending through the valve body and coupled in fluid communication with the first passageway. A valve member formed of an elastic material overlies the valve seat, defining a normally closed, axially-extending valve opening therebetween. The valve member is movable between a normally closed position engaging the valve seat, and an open position with at least a segment of the valve member spaced away from the valve seat to connect the valve opening in fluid communication with the flow aperture. A hermetically sealed variable-volume storage chamber stores therein multiple portions of the fluid and is connectible in fluid communication with the one-way valve assembly. A pump pumps discrete portions of fluid from the chamber, through the flow aperture and through the valve opening to dispense the portions of fluid therethrough.
摘要翻译：一种装置，包括限定第一通道的阀体，阀座和延伸穿过阀体并与第一通道流体连通地联接的流动孔。由弹性材料形成的阀构件覆盖在阀座上，在其间限定一个常闭的，轴向延伸的阀开口。阀构件可以在接合阀座的常闭位置和打开位置之间移动，其中阀构件的至少一段与阀座间隔开，以连接与开口流体连通的阀开口。气密密封的可变容积储存室在其中存储有多个流体部分，并可与单向阀组件流体连通。泵将来自腔室的分离的部分流体泵送通过流动孔并通过阀门开口以分配流体的部分。

58. 发明授权

US07780023B2 Ready to drink container with nipple and needle penetrable and laser resealable portion, and related method 有权
标题翻译：准备饮用容器，乳头和针头可穿透，激光可再密封部分，以及相关方法
公开(公告)号：US07780023B2
公开(公告)日：2010-08-24
申请号：US11786206
申请日：2007-04-10
申请人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willey
发明人： Daniel Py , Benoit Adamo , John Guthy , Nathaniel Houle , Brian Tulley , Jeffrey Willey
IPC分类号： A61J9/00 , A61J11/04
CPC分类号： A61J11/0005 , A61J1/1406 , A61J9/003 , A61J11/04 , B65D51/002
摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.
摘要翻译：提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

59. 发明授权

US07628184B2 Adjustable needle filling and laser sealing apparatus and method 有权
标题翻译：可调式针头灌装和激光密封装置及方法
公开(公告)号：US07628184B2
公开(公告)日：2009-12-08
申请号：US10983178
申请日：2004-11-05
申请人： Daniel Py , Benoit Adamo , John Guthy
发明人： Daniel Py , Benoit Adamo , John Guthy
IPC分类号： B65B1/04 , B65B51/10 , A61M5/32
CPC分类号： B65B3/006 , A61L2/10 , A61M5/1782 , B29C66/80 , B65B3/003 , B65B43/00 , B65B51/00 , Y10T29/49716
摘要： An assembly includes a support and drive assembly, a first structure and a second structure. The first structure is in operable communication with and supported by the support and drive assembly. The first structure includes at least one needle assembly and is adjustable to receive a plurality of needle assemblies. The second structure is supported by the support and drive assembly. The second structure includes at least one seal assembly and is adjustable to receive a plurality of seal assemblies. A method includes determining a number of vials that are to be filled concurrently and adjusting an assembly to include at least one needle assembly and at least one seal assembly. A number of the needle assemblies and the seal assemblies equals the number of vials.
摘要翻译：组件包括支撑和驱动组件，第一结构和第二结构。第一结构与支撑和驱动组件可操作地连通并由其支撑。第一结构包括至少一个针组件，并且可调节以接收多个针组件。第二个结构由支撑和驱动组件支撑。第二结构包括至少一个密封组件，并且可调节以接收多个密封组件。一种方法包括确定要同时填充的小瓶的数量并且调整组件以包括至少一个针组件和至少一个密封组件。许多针组件和密封组件等于小瓶的数量。

60. 发明申请

US20070194045A1 One-way valve and apparatus and method of using the valve 有权
公开(公告)号：US20070194045A1
公开(公告)日：2007-08-23
申请号：US11650102
申请日：2007-01-05
申请人： Daniel Py , Julian Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B65D35/56 , B65D37/00
CPC分类号： B67D1/108 , B05B11/00444 , B65B39/004 , B65D51/002 , B65D51/1616 , B67D1/0004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/0801 , B67D1/10 , B67D1/1279 , B67D3/0067 , B67D3/04 , B67D2001/0827 , F04B53/1037
摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat. A valve cover is mounted on the valve body, and includes an axially-extending portion formed of an elastic material overlying the valve seat and covering a substantial axially-extending portion thereof. The valve portion defines a predetermined radial thickness and forms an interference fit with the valve seat. The valve portion and the valve seat define an axially-extending seam therebetween forming a normally closed, axially-extending valve opening, and the valve portion is movable radially between (i) a normally closed position with the valve portion engaging the valve seat, and (ii) an open position with at least a segment of the valve portion spaced radially away from the valve seat to connect the valve opening in fluid communication with the at least one flow aperture and thereby allow the passage of substance from the variable-volume storage chamber through the valve opening. In the normally closed and open positions, the one-way valve maintains substance remaining in the variable-volume storage chamber in an aseptic condition and sealed with respect to the ambient atmosphere.

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