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51. 发明申请

US20110305889A1 Item with at least one thermoprogrammable switching section for applications in contact with materials having high heat transfer coefficients 有权
标题翻译：具有至少一个可编程热切换部件的物品，用于与具有高传热系数的材料接触
公开(公告)号：US20110305889A1
公开(公告)日：2011-12-15
申请号：US13126822
申请日：2009-10-30
申请人： Thomas Weigel , Andreas Lendlein , Karola Lutzow , Frank Klein , Samy Madbouly
发明人： Thomas Weigel , Andreas Lendlein , Karola Lutzow , Frank Klein , Samy Madbouly
IPC分类号： B32B3/26 , C08J9/00 , B05D1/02 , B32B7/02 , B82Y30/00
CPC分类号： B29C61/0625 , A61B17/06166 , A61B2017/00871 , A61B2017/0619 , Y10T428/24942 , Y10T428/249953
摘要： The present invention provides an article with at least one switching segment. The switching segment comprises a shape-memory compound and an isolating region surrounding the shape memory compound. The present invention also provides a method of producing such an article.
摘要翻译：本发明提供一种具有至少一个切换段的物品。切换部分包括形状记忆化合物和围绕形状记忆化合物的隔离区域。本发明还提供了制造这种制品的方法。

52. 发明申请

US20110092609A1 PHOTOSENSITIVE POLYMERIC NETWORKS 有权
标题翻译：光敏聚合物网络
公开(公告)号：US20110092609A1
公开(公告)日：2011-04-21
申请号：US12878559
申请日：2010-09-09
申请人： Andreas Lendlein , Hong-Yan Jiang , Oliver Jünger
发明人： Andreas Lendlein , Hong-Yan Jiang , Oliver Jünger
IPC分类号： C08L33/08 , C08L33/10 , C07C69/73
CPC分类号： C08F283/00 , A61L27/50 , A61L2400/16 , C08F265/04
摘要： The present invention related to amorphous photosensitive networks. The networks are characterized by good shape memory properties.
摘要翻译：本发明涉及非晶感光网络。网络的特点是良好的形状记忆特性。

53. 发明申请

US20090036627A1 AMORPHOUS POLYMERIC NETWORKS 审中-公开
标题翻译：非晶聚合物网络
公开(公告)号：US20090036627A1
公开(公告)日：2009-02-05
申请号：US12246262
申请日：2008-10-06
申请人： Andreas Lendlein , Nokyoung Choi
发明人： Andreas Lendlein , Nokyoung Choi
IPC分类号： C08F220/26
CPC分类号： C08G63/912 , C08G63/664
摘要： The present invention relates to amorphous phase segregated networks of ABA triblock copolymers. The networks do possess good shape memory properties. The materials of the present invention are in particular suitable as materials in the medicinal field, as implants, for the target designed stimuli sensitive drug release, for ligament augmentation or as disc replacement.
摘要翻译：本发明涉及ABA三嵌段共聚物的非晶相分离网络。网络确实具有良好的形状记忆特性。本发明的材料特别适合作为药物领域中的材料，作为植入物，用于靶设计的刺激敏感药物释放，用于韧带增大或椎间盘置换。

54. 发明申请

US20090023827A1 METHOD OF PREPARING SHAPE MEMORY MATERIALS STARTING FROM STANDARD THERMOPLASTIC POLYMERS 审中-公开
标题翻译：从标准热塑性聚合物制备形状记忆材料的方法
公开(公告)号：US20090023827A1
公开(公告)日：2009-01-22
申请号：US12095259
申请日：2006-11-28
申请人： Andreas Lendlein
发明人： Andreas Lendlein
IPC分类号： C08F110/00 , C08G63/44 , C08F12/08 , C08G63/00 , C08G18/44
CPC分类号： C08J3/24 , C08J3/28
摘要： The present invention concerns method of preparing shape memory materials starting from standard thermoplastic polymers. The present invention further is concerned with products obtained by the methods in accordance with the present invention and the use of these products over a wide variety of applications.
摘要翻译：本发明涉及从标准热塑性聚合物开始制备形状记忆材料的方法。本发明还涉及通过根据本发明的方法获得的产品以及这些产品在各种应用中的使用。

55. 发明申请

US20080319132A1 Amorphous Polyester Urethane Networks Having Shape Memory Properties 审中-公开
标题翻译：具有形状记忆特性的无定形聚酯聚氨酯网络
公开(公告)号：US20080319132A1
公开(公告)日：2008-12-25
申请号：US10570073
申请日：2004-08-16
申请人： Andreas Lendlein , Armin Alteheld
发明人： Andreas Lendlein , Armin Alteheld
IPC分类号： C08L75/00 , C08G18/48 , C08G18/42
CPC分类号： C08G18/4283 , C08G18/4018 , C08G18/428 , C08G18/4887 , C08G18/73 , C08G18/755 , C08G18/758 , C08G2220/00 , C08G2230/00 , C08G2270/00 , C08G2280/00
摘要： In order to avoid structural heterogeneities in the networks, in accordance with the invention under consideration, a novel system of amorphous polymer networks comprising one or several segments with shape memory properties is provided. The networks are preferably composed of biodegradable and biocompatible components and open up the possibility for use in the medical domain. The systemic character of the materials allows the thermal and mechanical properties as well as the decomposition behavior to be adjusted in a specific manner. The invention under consideration particularly makes it possible to produce polyphase amorphous networks.
摘要翻译：为了避免网络中的结构异质性，根据所考虑的本发明，提供了一种包含具有形状记忆特性的一个或多个片段的无定形聚合物网络的新系统。网络优选由可生物降解和生物相容的组分组成，并且开放了在医学领域中使用的可能性。材料的系统性质允许以特定方式调节热和机械性能以及分解行为。正在考虑的发明特别地使得可以生产多相非晶网络。

56. 发明授权

US07217744B2 Polymeric networks 有权
标题翻译：聚合网络
公开(公告)号：US07217744B2
公开(公告)日：2007-05-15
申请号：US10375210
申请日：2003-02-26
申请人： Andreas Lendlein , Annette Schmidt , Nok Young Choi
发明人： Andreas Lendlein , Annette Schmidt , Nok Young Choi
IPC分类号： C08G63/08 , C08L67/07 , C08L33/08 , C08F2/46
CPC分类号： C08L67/07 , C08F283/00 , C08F290/06 , C08F290/061 , C08G63/08 , Y10S525/903
摘要： The present invention relates to polymeric networks, which are characterised by particular mechanical properties and which, furthermore, allow the control of thermal and mechanical properties by simple variation of the components.
摘要翻译：本发明涉及聚合物网络，其特征在于具有特定的机械性能，并且还可以通过组件的简单变化来控制热和机械性能。

57. 发明申请

US20070088135A1 Blends with shape memory characteristics 审中-公开
标题翻译：混合形状记忆特性
公开(公告)号：US20070088135A1
公开(公告)日：2007-04-19
申请号：US10552654
申请日：2004-03-23
申请人： Andreas Lendlein , Ute Ridder
发明人： Andreas Lendlein , Ute Ridder
IPC分类号： C08L67/00 , C08G63/02 , C08G63/08
CPC分类号： C08L87/005 , C08G18/4202 , C08G18/425 , C08G18/4277 , C08G18/4283 , C08G18/73 , C08G63/912 , C08G63/914 , C08G2230/00 , C08G2280/00 , C08L53/00 , C08L67/025 , C08L67/04 , C08L2666/02 , C08L2666/18
摘要： The invention relates to a polymer blend with shape-memory characteristic comprising two different block copolymers each containing at least one hard segment and at least one soft segment, whereby the two different block copolymers comprise the same soft segment and only differ with regard to the hard segment.
摘要翻译：本发明涉及具有形状记忆特征的聚合物共混物，其包含两种不同的嵌段共聚物，每种嵌段共聚物含有至少一个硬链段和至少一个软链段，由此两种不同的嵌段共聚物包含相同的软链段，并且仅在硬分割。

58. 发明申请

US20060142794A1 Self-expanding device for the gastrointestinal or urogenital area 审中-公开
标题翻译：用于胃肠道或泌尿生殖区域的自扩张装置
公开(公告)号：US20060142794A1
公开(公告)日：2006-06-29
申请号：US10546092
申请日：2004-02-18
申请人： Andreas Lendlein , Robert Langer
发明人： Andreas Lendlein , Robert Langer
IPC分类号： A61M29/00
CPC分类号： A61K9/0065 , A61F2/04 , A61F6/00 , A61F2210/0004 , A61K9/0034 , A61K9/0036
摘要： Devices for treatments of diseases and disorders associated with the gastrointestinal tract, especially the stomach, or urinogenital tract are described herein. Initially, the device is in a temporary form which is suitable for oral or rectal administration. After exposure to a stimulus, such as a temperature or pH change, the device changes shape to a permanent form, which allows it to become mechanically fixed in the stomach, esophagus or intestine. In one embodiment, the device is used to reduce the volume of the stomach, esophagus or intestine without interfering with the flow of the food through the gastrointestinal tract. The device may be used to help overweight patients lose weight and to deliver drugs to treat disorders and diseases in the in the stomach or intestine. The devices are manufactured from a stimuli-sensitive polymeric material, which is biocompatible and primarily adapted to the mechanical properties and geometry in the area to which it is applied. In the preferred embodiment, the material is a shape memory polymer. Depending on the desired application, the polymer may be either biodegradable or non-degradable.
摘要翻译：用于治疗与胃肠道，特别是胃或泌尿生殖道相关的疾病和病症的装置在本文中描述。最初，该装置是适合口服或直肠给药的临时形式。在暴露于诸如温度或pH变化的刺激之后，该装置将形状改变为永久形式，这使其能够机械地固定在胃，食道或肠中。在一个实施方案中，该装置用于减少胃，食道或肠的体积，而不干扰食物通过胃肠道的流动。该装置可以用于帮助超重患者减肥并且递送药物以治疗胃或肠内的疾病和疾病。这些装置由刺激敏感的聚合物材料制成，其是生物相容的并且主要适应于其所应用的区域的机械性质和几何形状。在优选实施例中，该材料是形状记忆聚合物。取决于所需的应用，聚合物可以是可生物降解的或不可降解的。

59. 发明申请

US20050202067A1 Matrix structure and hybrid matrix system for inducing a neofacia, their use and method for generating a neofacia 审中-公开
标题翻译：用于诱导新角质的基质结构和杂合基质体系，其用于产生新角质的方法
公开(公告)号：US20050202067A1
公开(公告)日：2005-09-15
申请号：US10974541
申请日：2004-10-27
申请人： Andreas Lendlein , Karola Lutzow , Steffen Kelch , Thomas Groth , Heinz Buhr , Christoph Isbert , Christoph-Thomas Germer , Christoph Reissfelder , Jorg-P. Ritz
发明人： Andreas Lendlein , Karola Lutzow , Steffen Kelch , Thomas Groth , Heinz Buhr , Christoph Isbert , Christoph-Thomas Germer , Christoph Reissfelder , Jorg-P. Ritz
IPC分类号： A61F2/00 , A61F2/08 , A61K9/70 , A61L27/04 , A61L27/38 , A61L27/50 , A61L27/58
CPC分类号： A61F2/0063 , A61L27/3804 , A61L27/3843 , A61L27/58
摘要： The invention is directed to a matrix structure for inducing a neofascia with at least one two-dimensional matrix of at least one biocompatible and resorbable polymer, wherein the surface of the matrix is designed to immobilize tissue cells, in particular autologous fibrocytes of the fascia transversalis, and to reduce a preferably three-dimensional tissue growth in vitro or in vivo. The invention is also directed to a hybrid matrix system, which includes the matrix structure and tissue cells immobilized thereon. The novel matrix as well as the fascia hybrid are characterized by a high biocompatibility and overcome the disadvantages of non-degradable implants, thereby promoting formation of a neofascia with native biomechanical properties.
摘要翻译：本发明涉及用于诱导具有至少一种生物相容性和可再吸收的聚合物的至少一种二维基质的新筋膜的基质结构，其中所述基质的表面被设计成固定组织细胞，特别是固定在横筋膜的自体纤维细胞并且在体外或体内减少优选的三维组织生长。本发明还涉及一种混合基质系统，其包括固定在其上的基质结构和组织细胞。新型基质以及筋膜混合物的特征在于生物相容性高，克服了不可降解植入物的缺点，从而促进了具有天然生物力学性质的新筋膜的形成。

60. 发明授权

US6160084A Biodegradable shape memory polymers 有权
标题翻译：可生物降解形状记忆聚合物
公开(公告)号：US6160084A
公开(公告)日：2000-12-12
申请号：US256620
申请日：1999-02-23
申请人： Robert S. Langer , Andreas Lendlein , Annette Schmidt , Hans Grablowitz
发明人： Robert S. Langer , Andreas Lendlein , Annette Schmidt , Hans Grablowitz
IPC分类号： A61C7/00 , A61B17/58 , A61F5/01 , A61K47/30 , A61L27/00 , A61L27/14 , A61L27/18 , A61L27/50 , A61L27/58 , A61L29/00 , A61L29/04 , A61L29/14 , A61L31/00 , A61L31/04 , A61L31/14 , C08G18/48 , C08L101/00 , C08L101/16 , C08G63/02
CPC分类号： A61L31/148 , A61B2017/00871 , A61L27/18 , A61L27/50 , A61L27/58 , A61L29/148 , A61L2400/16
摘要： Biodegradable shape memory polymer compositions, articles of manufacture thereof, and methods of preparation and use thereof are described. In one embodiment the compositions include at least one hard segment and at least one soft segment. The T.sub.trans of the hard segment is preferably between -30 and 270.degree. C. At least one of the hard or soft segments can contain a crosslinkable group, and the segments can be linked by formation of an interpenetrating network or a semi-interpenetrating network, or by physical interactions of the segments. Objects can be formed into a given shape at a temperature above the T.sub.trans of the hard segment, and cooled to a temperature below the T.sub.trans of the soft segment. If the object is subsequently formed into a second shape, the object can return to its original shape by heating the object above the T.sub.trans of the soft segment and below the T.sub.trans of the hard segment.
摘要翻译：描述了可生物降解形状记忆聚合物组合物，其制备方法及其制备和使用方法。在一个实施方案中，组合物包括至少一个硬链段和至少一个软链段。硬链段的Ttrans优选在-30至270℃之间。至少一个硬链段或软链段可含有可交联基团，并且链段可通过形成互穿网络或半互穿网络而连接，或通过细分的物理相互作用。物体可以在高于硬链段的Ttrans的温度下形成给定的形状，并且被冷却到低于软链段的Ttrans的温度。如果对象随后形成第二形状，则可以通过将软部分的Ttrans上方的物体加热到硬片段的Ttrans下面，物体可以返回到其原始形状。

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