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51. 发明申请

US20110166354A1 METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO ACID DERIVATIVE 有权
标题翻译：生产光学活性氨基酸衍生物的方法
公开(公告)号：US20110166354A1
公开(公告)日：2011-07-07
申请号：US12993661
申请日：2009-06-02
申请人： Shohei Yamamoto , Akio Fujii , Masaru Mitsuda
发明人： Shohei Yamamoto , Akio Fujii , Masaru Mitsuda
IPC分类号： C07C227/08 , C07D207/06 , C07D495/04 , C07D401/12 , C07D211/60
CPC分类号： C07B51/00 , C07B53/00 , C07C227/18 , C07C229/08 , C07C229/28 , C07C2601/02 , C07D207/12 , C07D211/60 , C07D295/18 , C07D403/12 , C07D495/04
摘要： The present application relates to a method for producing an optically active α-amino acid derivative, comprising steps of reacting an α-haloester derivative represented by the general formula (1): of which alcohol part of the ester group is an optically active alcohol derivative, with an amine compound; then deprotecting the obtained compound; further carrying out an ester exchange reaction. According to the present invention method, it is possible to easily produce an optically active α-amino acid ester derivative which is useful as an intermediate for drugs with high selectivity.
摘要翻译：本申请涉及一种光学活性α-氨基酸衍生物的制造方法，包括使由通式（1）表示的α-卤代酯衍生物：酯基的醇部分为光学活性醇衍生物，与胺化合物; 然后使所得化合物脱保护; 进一步进行酯交换反应。根据本发明的方法，可以容易地制备可用作高选择性药物的中间体的光学活性α-氨基酸酯衍生物。

52. 发明申请

US20110058973A1 MOTOR-DRIVEN COMPRESSOR 有权
标题翻译：电机驱动压缩机
公开(公告)号：US20110058973A1
公开(公告)日：2011-03-10
申请号：US12877249
申请日：2010-09-08
申请人： Tetsuya YAMADA , Shingo Enami , Akio Fujii , Junya Yano , Ken Suitou
发明人： Tetsuya YAMADA , Shingo Enami , Akio Fujii , Junya Yano , Ken Suitou
IPC分类号： F04C15/00 , F04C2/02
CPC分类号： F04C23/008 , F04C18/0215 , F04C2240/30 , F04C2240/803 , H01R13/405 , H01R13/533 , H02G3/22 , H02K5/12 , H02K5/225
摘要： A motor-driven compressor includes a compression mechanism, an electric motor, a compressor housing, a conductive member, a terminal base, an insulating member, a connection terminal, a wire assembly, a terminal housing, first and second holes formed through the terminal housing and first and second seal members. The conductive member extends from the inside to the outside of the compressor housing and connected electrically to the connection terminal at a terminal connection. The wire assembly has a core wire connecting electrically between the connecting terminal and the electric motor, and an insulator covering the core wire. The terminal housing disposed in the compressor housing covers the terminal connection. The wire assembly has an insulating tube covering the insulator, wherein both ends of the insulating tube are opened for communicating with the inside and the outside of the terminal housing through a clearance formed between the insulating tube and the insulator.
摘要翻译：电动压缩机包括压缩机构，电动机，压缩机壳体，导电构件，端子座，绝缘构件，连接端子，线组件，端子壳体，通过端子形成的第一和第二孔外壳和第一和第二密封件。导电构件从压缩机壳体的内部延伸到外部并且在端子连接处电连接到连接端子。线组件具有在连接端子和电动机之间电连接的芯线，以及覆盖芯线的绝缘体。设置在压缩机壳体中的端子壳体覆盖端子连接。电线组件具有覆盖绝缘体的绝缘管，其中绝缘管的两端被打开以通过形成在绝缘管和绝缘体之间的间隙与端子壳体的内部和外部连通。

53. 发明申请

US20110009609A1 2'-HYDROXY-PROTECTED RIBONUCLEOSIDE DERIVATIVE AND PRODUCTION METHOD THEREOF 失效
标题翻译： 2'-羟基保护的核糖核苷衍生物及其生产方法
公开(公告)号：US20110009609A1
公开(公告)日：2011-01-13
申请号：US12919295
申请日：2009-02-26
申请人： Hirofumi Maeda , Akio Fujii , Masaru Mitsuda
发明人： Hirofumi Maeda , Akio Fujii , Masaru Mitsuda
IPC分类号： C07H19/22 , C07H19/00
CPC分类号： C07H19/067 , C07H19/167
摘要： The present invention relates to a method for producing a 2′-hydroxy-protected nucleoside derivative by reacting a ribonucleoside with an acylating reagent in the presence of a metal complex consisting of a copper compound and an optically active ligand. By the method according to the present invention, a 2′-hydroxy-protected ribonucleoside derivative, which is an important intermediate for producing an oligonucleoside, can be easily produced with good regioselectivity from a nucleoside derivative of which 2′,3′-hydroxy groups are not protected.
摘要翻译：本发明涉及通过在由铜化合物和光学活性配体组成的金属络合物的存在下使核糖核苷与酰化剂反应来制备2'-羟基保护的核苷衍生物的方法。通过本发明的方法，可以容易地制备作为制备寡核苷酸的重要中间体的2'-羟基保护的核糖核苷衍生物，其从2'，3'-羟基的核苷衍生物具有良好的区域选择性没有保护。

54. 发明申请

US20100191011A1 METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF 失效
标题翻译：生产光学活性羟基羧酸衍生物或其盐的方法
公开(公告)号：US20100191011A1
公开(公告)日：2010-07-29
申请号：US12376803
申请日：2007-08-08
申请人： Susumu Amano , Akio Fujii , Shohei Yamamoto , Masaru Mitsuda
发明人： Susumu Amano , Akio Fujii , Shohei Yamamoto , Masaru Mitsuda
IPC分类号： C07C51/347
CPC分类号： C07B53/00 , C07B2200/07 , C07C51/00 , C07C51/367 , C07C201/12 , C07C59/48 , C07C205/56
摘要： The present invention has its object to provide a method for producing an optically active hydroxycarboxylic acid derivative which is an intermediate important for production of medicines, agrochemicals, chemical products, and so on. The production method of the present invention comprises: carrying out a hydrogen-transfer reduction of a ketocarboxylic acid or a salt thereof by the reaction of an optically active diamine complex to produce an optically active hydroxycarboxylic acid derivative. According to the present invention, it is possible to safely and efficiently produce an industrially-useful optically active hydroxycarboxylic acid derivative.
摘要翻译：本发明的目的在于提供一种光学活性羟基羧酸衍生物的制造方法，该方法是制备药物，农药，化学品等的重要中间体。本发明的制造方法包括：通过光学活性二胺配合物的反应进行酮羧酸或其盐的氢转移还原反应，生成光学活性羟基羧酸衍生物。根据本发明，可以安全有效地制备工业上有用的光学活性羟基羧酸衍生物。