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    • 56. 发明授权
    • Method and system for determining settings for deep brain stimulation
    • 用于确定深部脑刺激设置的方法和系统
    • US09265932B2
    • 2016-02-23
    • US13575965
    • 2011-02-02
    • Hubert Cécile François MartensMichel Marcel Jose DecréKevin Thomas Dolan
    • Hubert Cécile François MartensMichel Marcel Jose DecréKevin Thomas Dolan
    • A61N1/36A61N1/05
    • A61N1/0534A61N1/36082A61N1/36185
    • A method and control system for determining and applying stimulation settings for a brain stimulation probe (10, 12) is provided. The brain stimulation probe (10, 12) comprises a plurality of stimulation electrodes (11). The method comprises for multiple stimulation electrodes (11) of the plurality of stimulation electrodes (11): applying a test current and determining a corresponding patient response, determining a volume of influence based (32, 52, 71, 91) on the test current and a position of the stimulation electrode (11), combining the volume of influence (32, 52, 71, 91) and the corresponding patient response with generalized anatomic knowledge of stimulation induced behavior for associating the volume of influence (32, 52, 71, 91) to an anatomic structure (33, 43, 53), and determining an intersection (41, 51) of the volume of influence (32, 52, 71, 91) and the associated anatomic structure (33, 43, 53). Then, based on the determined intersections (41, 51) an optimal stimulation volume and corresponding stimulation settings for the brain stimulation probe (10, 12) are determined.
    • 提供了一种用于确定和应用脑刺激探针(10,12)的刺激设置的方法和控制系统。 脑刺激探针(10,12)包括多个刺激电极(11)。 该方法包括多个刺激电极(11)的多个刺激电极(11):施加测试电流并确定相应的患者反应,确定基于(32,52,71,91)的测试电流的影响体积 以及刺激电极(11)的位置,将影响体积(32,52,71,91)和相应的患者反应与刺激诱发行为的广义解剖学知识相结合以影响体积(32,52,71) ,91)到解剖结构(33,43,53),并且确定影响体积(32,52,71,91)和相关联的解剖结构(33,43,53)的交叉点(41,51) 。 然后,基于确定的交叉点(41,51),确定用于脑刺激探针(10,12)的最佳刺激体积和相应的刺激设置。