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51. 发明申请

US20180235635A1 SURGICAL STAPLER, ANVIL FOR A SURGICAL STAPLER, AND A METHOD OF STAPLING TISSUE 审中-公开
公开(公告)号：US20180235635A1
公开(公告)日：2018-08-23
申请号：US15551385
申请日：2017-06-28
申请人： Norwegian University of Science and Technology (NTNU)
发明人： Lars Cato REKSTAD , Brynjulf YSTGAARD
IPC分类号： A61B17/115 , A61B17/072
CPC分类号： A61B17/1155 , A61B17/072 , A61B2017/07257 , A61B2017/1157
摘要： A surgical stapler 101 comprises a proximal end and a distal end, wherein the proximal end is proximate to the user in use and the distal end is distal from the user in use and an anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 at the distal end for providing resistance to staples during the stapling operation of the surgical stapler. The anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 is configured to be actuated between a deployed state and a collapsed state. The anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 comprises a plurality of segments 130, 230, 330, 430, 530, 630, 730, 830, 930 arranged end-to-end. The anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 is elongated in the collapsed state, the anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 being elongated generally in a first direction D1. When viewed along the first direction D1 the area covered by the anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 is greater in the deployed state than the collapsed state. The anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 is configured such that the segments 130, 230, 330, 430, 530, 630, 730, 830, 930 rotate about a rotation axis along a second direction D2 perpendicular to the first direction D1 when the anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 is actuated between the deployed and the collapsed states. The anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 is configured such that adjacent segments 130, 230, 330, 430, 530, 630, 730, 830, 930 pivot relative to each other about a pivot axis along a third direction D3 perpendicular to the second direction D2 when the anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 is actuated between the deployed and collapsed states. The stapler 101 also comprises an actuator mechanism 470, 770, 1070, configured to actuate the anvil 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320 between the deployed and collapsed states, wherein the actuator mechanism 470, 770, 1070 is configured to be controlled from a location on the surgical stapler towards the proximal end.

52. 发明申请

US20180204977A1 NANOWIRES/NANOPYRAMIDS SHAPED LIGHT EMITTING DIODES AND PHOTODETECTORS 审中-公开
公开(公告)号：US20180204977A1
公开(公告)日：2018-07-19
申请号：US15744467
申请日：2016-07-13
申请人： CRAYONANO AS , NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
发明人： Dasa L. DHEERAJ , Dong Chul KIM , Bjørn Ove M. FIMLAND , Helge WEMAN
IPC分类号： H01L33/08 , H01L33/18 , H01L33/24 , H01L31/0352 , H01L33/06 , H01L33/32
CPC分类号： H01L33/08 , H01L31/035227 , H01L31/1035 , H01L31/105 , H01L31/184 , H01L31/1852 , H01L33/06 , H01L33/18 , H01L33/24 , H01L33/325
摘要： A light emitting diode device comprising: a plurality of nanowires or nanopyramids grown on a graphitic substrate, said nanowires or nanopyramids having a p-n or p-i-n junction, a first electrode in electrical contact with said graphitic substrate; a light reflective layer in contact with the top of at least a portion of said nanowires or nanopyramids, said light reflective layer optionally acting as a second electrode; optionally a second electrode in electrical contact with the top of at least a portion of said nanowires or nanopyramids, said second electrode being essential where said light reflective layer does not act as an electrode; wherein said nanowires or nanopyramids comprise at least one group III-V compound semiconductor; and wherein in use light is emitted from said device in a direction substantially opposite to said light reflective layer.

53. 发明授权

US09946234B2 Control of flow networks 有权
公开(公告)号：US09946234B2
公开(公告)日：2018-04-17
申请号：US14780882
申请日：2014-04-17
申请人： NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
发明人： Bjarne Foss , Vidar Gunnerud
IPC分类号： G05B13/04 , E21B41/00 , E21B43/34 , E21B43/00
CPC分类号： G05B13/041 , E21B41/00 , E21B43/00 , E21B43/34
摘要： A method for control of a flow network in order to improve the performance of the flow network comprises: (a) applying predetermined excitations at multiple control points within the flow network, wherein the multiple control points are at different branches of the flow network; (b) receiving measurements of changes in one or more flow parameter(s) in one or more flow path(s) in which flows of more than one of the different branches have been combined; (c) carrying out an analysis of the flow parameter measurements to identify variations induced by the applied excitations; (d) determining an adjustment to be made at one or more of the control point(s) in order to improve the performance of the flow network, for example by building and solving an optimization model; (e) making the determined adjustment to the control point(s) of the flow network or making an alternative adjustment decided upon by the flow network operator; and (f) repeating steps (a) to (e) one or more times to thereby iteratively improve the performance of the flow network.

54. 发明申请

US20160138390A1 Drilling Method and Apparatus 审中-公开
标题翻译：钻孔方法和装置
公开(公告)号：US20160138390A1
公开(公告)日：2016-05-19
申请号：US14893537
申请日：2014-06-06
申请人： Norwegian University of Science and Technology (NTNU)
发明人： Børge ARNTSEN , Sigbjørn SANGESLAND , Ståle Emil JOHANSEN
IPC分类号： E21B47/14 , E21B47/024 , E21B7/06
CPC分类号： E21B47/14 , E21B7/04 , E21B7/043 , E21B7/06 , E21B47/02208 , E21B47/024 , E21B47/09 , E21B47/091 , G01V1/42
摘要： A method of locating a drilling apparatus and/or a borehole in a subterranean region. The method may include the steps of transmitting seismic waves into the subterranean region during a subterranean drilling operation, the seismic waves being transmitted from a location remote from the drilling apparatus, detecting a seismic response from the drilling apparatus or borehole, and comparing the detected response with predetermined seismic survey data of the subterranean region to determine the location of the apparatus or borehole.
摘要翻译：一种在地下区域中定位钻井设备和/或钻孔的方法。该方法可以包括以下步骤：在地下钻井操作期间将地震波发射到地下区域，地震波从远离钻井设备的位置传输，检测来自钻井设备或井眼的地震响应，并比较检测到的响应利用地下区域的预定地震勘测数据来确定装置或钻孔的位置。

55. 发明申请

US20150306188A1 TREATMENT OF HEADACHE BY INJECTION OF NEUROINHIBITORY SUBSTANCE TO SPHENOPALATINE GANGLION OR OTIC GANGLION 有权
标题翻译：通过注射神经元药物治疗脊髓灰质炎或油性炎症治疗头颅
公开(公告)号：US20150306188A1
公开(公告)日：2015-10-29
申请号：US14426303
申请日：2013-09-06
申请人： NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
发明人： Daniel Fossum Bratbak , Ståle Nordgård
IPC分类号： A61K38/48 , A61M5/32 , A61M5/28 , A61K9/00
CPC分类号： A61K38/4893 , A61B10/0233 , A61B17/3403 , A61B2010/0208 , A61B2017/00199 , A61B2034/2051 , A61B2034/2055 , A61B2034/2068 , A61B2090/372 , A61B2090/3937 , A61B2090/397 , A61B2090/3983 , A61K9/0019 , A61M5/20 , A61M5/24 , A61M5/28 , A61M5/3286 , A61M2005/206 , A61M2209/01 , A61M2210/0687 , A61N1/372 , A61P25/06 , A61P27/02
摘要： A neuroinhibitory substance for use in a method for treating or preventing headache comprising injecting a neuroinhibitory substance such as botulinium toxin in close proximity to the sphenopalatine ganglion or otic ganglion wherein an injection device comprising said neuroinhibitory substance is brought into close proximity to the sphenopalatine ganglion or otic ganglion by inserting said injection device into the patient transnasally or infrazygomatically and the neuroinhibitory substance injected in close proximity to the SPG or OG.
摘要翻译：用于治疗或预防头痛的方法中的神经抑制物质，其包括将神经抑制物质如肉毒毒素神经节或神经节神经节附近注射，其中将包含所述神经抑制物质的注射装置置于邻近的蝶腭神经节或通过将所述注射装置经鼻或非激素地插入到患者中，并且紧密地注入SPG或OG注射的神经抑制物质来治疗耳神经节。

56. 发明申请

US20150265769A1 INTERVENTION DEVICE 审中-公开
标题翻译：干预设备
公开(公告)号：US20150265769A1
公开(公告)日：2015-09-24
申请号：US14426283
申请日：2013-09-06
申请人： NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
发明人： Daniel Fossum Bratbak , Ståle Nordgård
IPC分类号： A61M5/20 , A61M5/24 , A61B10/02
摘要： A device for interventions within the body, the device comprising: an end piece 6 for insertion into the body at a distal end thereof, the end piece 6 including a rigid lumen for holding an instrument 10 and guiding the instrument 10 to the distal end of the end piece; and a body section 4 supporting the lumen and being rigidly connected thereto, the body section including a navigation array 14 for guidance of the device using a surgical navigation system and/or including an anchor point 20 for a standard navigation array.
摘要翻译：一种用于身体内的干预的装置，该装置包括：用于在其远端插入身体的端片6，端片6包括用于保持器械10的刚性内腔，并将器械10引导到端片; 以及支撑内腔并刚性地连接到其上的主体部分4，主体部分包括用于使用外科导航系统引导装置的导航阵列14和/或包括用于标准导航阵列的锚点20。

57. 发明公开

US20240132673A1 POLYMER WITH IMPROVED FRACTURE TOUGHNESS 审中-公开
公开(公告)号：US20240132673A1
公开(公告)日：2024-04-25
申请号：US18283693
申请日：2022-03-22
申请人： NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
发明人： Yizhi ZHUO , Jianying HE , Zhiliang ZHANG
IPC分类号： C08G77/458 , C08L83/10
CPC分类号： C08G77/458 , C08L83/10 , C08L2207/04
摘要： A polymer comprising a structural unit of formula (I). wherein each X is independently a C1-10 hydrocarbylene group optionally comprising 1 to 6 heteroatoms: Y is a C2-20 hydrocarbylene group: Z is a C1-20 hydrocarbylene group optionally comprising 1 to 6 heteroatoms or a linking group comprising one or more alkylene glycol or ethylene diamine groups: n is 12 to 100; and m is 2 to 1000.

58. 发明授权

US11712464B2 Intervention device 有权
公开(公告)号：US11712464B2
公开(公告)日：2023-08-01
申请号：US16933481
申请日：2020-07-20
申请人： Norwegian University of Science and Technology (NTNU)
发明人： Daniel Fossum Bratbak , Ståle Nordgård
IPC分类号： A61B5/00 , A61K38/48 , A61B10/02 , A61B17/34 , A61P27/02 , A61N1/372 , A61P25/06 , A61M5/20 , A61M5/24 , A61K9/00 , A61M5/28 , A61M5/32 , A61B17/00 , A61B90/00 , A61B34/20
CPC分类号： A61K38/4893 , A61B10/0233 , A61B17/3403 , A61K9/0019 , A61M5/20 , A61M5/24 , A61M5/28 , A61M5/3286 , A61N1/372 , A61P25/06 , A61P27/02 , A61B2010/0208 , A61B2017/00199 , A61B2034/2051 , A61B2034/2055 , A61B2034/2068 , A61B2090/372 , A61B2090/397 , A61B2090/3937 , A61B2090/3983 , A61M2005/206 , A61M2209/01 , A61M2210/0687
摘要： A device for interventions within the body, the device comprising: an end piece 6 for insertion into the body at a distal end thereof, the end piece 6 including a rigid lumen for holding an instrument 10 and guiding the instrument 10 to the distal end of the end piece; and a body section 4 supporting the lumen and being rigidly connected thereto, the body section including a navigation array 14 for guidance of the device using a surgical navigation system and/or including an anchor point 20 for a standard navigation array.

59. 发明公开

US20230220047A1 PEPTIDES FOR TREATMENT OF SEPSIS AND CANCER 审中-公开
公开(公告)号：US20230220047A1
公开(公告)日：2023-07-13
申请号：US18008856
申请日：2021-06-10
申请人： NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
发明人： Maria YURCHENKO , Terje ESPEVIK , Harald HUSEBYE
IPC分类号： C07K14/705 , A61P35/00
CPC分类号： C07K14/70596 , A61P35/00 , C07K2319/10
摘要： The present invention provides oligopeptidic compounds comprising a first oligopeptidic component derived from SLAMF1 and a second oligopeptidic component which is a cell-penetrating peptide. The oligopeptidic compounds provided have been found unexpectedly to block signalling from TLR4, TLR7, TLR8 and TLR9 in response to stimulus by their ligands, and also to display an anti-proliferative effect on cancer cells. The oligopeptidic compounds provided may be used in therapy for conditions associated with overactive immune responses, such as sepsis, and for treatment of cancer.

60. 发明授权

US11497473B2 Ultrasound cardiac processing 有权
公开(公告)号：US11497473B2
公开(公告)日：2022-11-15
申请号：US16585034
申请日：2019-09-27
申请人： Norwegian University of Science and Technology (NTNU)
发明人： Sebastien Salles , Lasse Lovstakken , Hans Torp
IPC分类号： A61B8/08 , G06T15/08 , A61B8/00 , A61B5/318
摘要： A method of processing cardiac ultrasound data for determining information about a mechanical wave in the heart. The method comprises receiving data representative of a time series of three-dimensional data frames, generated from ultrasound signals from a human or animal heart, each frame comprising a set of voxels, each voxel value representing an acceleration component of a respective location in the heart at a common time. The method also comprises identifying, for each voxel, a frame of the series in which the voxel value is at a maximum. A three-dimensional time-propagation data set is generated by assigning each voxel a value representative of the time of the respective frame in the time series for which the corresponding voxel is at a maximum. The method then comprises generating data representative of a three-dimensional velocity vector field by calculating time derivatives from the three-dimensional time-propagation data set.

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