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51. 发明专利

GB2116859B BOARD GAME APPARATUS 未知
公开(公告)号：GB2116859B
公开(公告)日：1986-02-12
申请号：GB8218910
申请日：1982-06-30
申请人： ELLIOTT MICHAEL PAUL
发明人： ELLIOTT MICHAEL PAUL
IPC分类号： A63F3/02

52. 发明专利

GB2131362A Vehicle with pivotless wheels 未知
公开(公告)号：GB2131362A
公开(公告)日：1984-06-20
申请号：GB8329529
申请日：1983-11-04
申请人： LANE MICHAEL PAUL D ALCORN
发明人： LANE MICHAEL PAUL D ALCORN
IPC分类号： B62K1/00
摘要： The vehicle, which may be used as an all-weather sledge, has a platform 10 supported relatively rotatably one or more pivotless wheels 11. Each wheel 11 may engage an arcuate channel in guide means 14 fixed to the platform 10 (as shown) or, in a modification the guide means may engage a channel in the periphery of the wheel. The guide surface may extend throughout the inner periphery of the wheel. Contact between each wheel 11 and the guide means is preferably purely frictional, the wheels being held upright by the weight of the platforms 10 and a load thereon, such as a rider lying face down and gripping the bar 17 on top of the platform. Ground engaging ribs 18 for braking (or, in a modification, wheels) may be provided under the platform. The wheels 11 are demountable simply by lifting the platform 10. A motorised mountain rescue vehicle is disclosed with pivotless wheels capable of oscillating about eccentric axes.

53. 发明专利

GB954296A Improvements in or relating to diaphragms 未知
公开(公告)号：GB954296A
公开(公告)日：1964-04-02
申请号：GB3309659
申请日：1959-09-29
申请人： BRITISH FIBRAK SEPARATOR COMPA , MICHAEL PAUL LATHAM , ALBERT HARDY
IPC分类号： B05D1/38 , B32B27/00 , C08J9/24 , H01M2/14 , H01M2/16
摘要： 954,296. Coated fabrics. BRITISH FIBRAK SEPARATOR CO. Ltd., M. P. LATHAM, and A. HARDY. Sept. 1, 1960 [Sept. 29, 1959], No. 33096/59. Heading B2E. A permeable diaphragm material comprises a first layer 27 of a porous base material and a second layer 25 of porous sintered thermoplastic powder having a first average particle diameter, there being provided between the first and second layers a sintered thermoplastic powder 26 comprising particles having a second average particle diameter which is smaller than the first average particle diameter, and maintaining the first and second layers in intimate contact across substantially their whole surface to form a porous but effectively continuous bond between the layers. The diaphragm material may be an electric battery separator in which the first layer consists of a fibrous sheet which may comprise cellulose or glass, or a mixture thereof, e.g. about 10% glass fibre and 90% cellulose pulp, impregnated with cured acid-resisting resin, e.g. a water-soluble phenolic resin or polyvinyl chloride latex, which may contain a wetting agent. The second layer may be a layer of sintered powder having an average particle diameter of about 10 microns, and the sintered thermoplastic powder which provides the effectively continuous bond between the first and second layers may be a sintered mixture of a powder having an average particle diameter of from 0À5-1 micron and a powder having an average particle diameter of about 10 microns. A wetting agent may be incorporated in the sintered thermoplastic powder. Layer 25 may have ribs 28 in its surface. The face of the sintered layer and/or the non-coated face of the base material may have pores of predetermined size constituted by the interstices of a continuous lace-like network of thermoplastic extending over the face, the network comprising abutting finely divided particles of the thermoplastic sintered together at their points of contact and adhering to the face. The thermoplastic may be polyvinyl chloride, polyvinyl acetate, polyethylene or polymethyl methacrylate, which may be sintered at 220-230 C. The diaphragm material may be produced by coating a face of a porous base material with a mixture of finely divided particles of a thermoplastic containing at least two constituents of different average particle size such that the particles penetrate into the base material, covering the coating with a layer of finely divided particles of thermoplastic having an average particle size substantially the same as the larger of the constituents, and then sintering the thermoplastic to form a porous membrane which is continuously bonded to the base material by the sintered coating. In the production of an electric battery separator, the base material is a fibrous sheet impregnated with an acid-resisting resin which is partially or wholly cured, e.g. if a water soluble phenolic resin at 230-260 C., prior to the application of the particulate coating; the completion of the curing being effected after sintering. The coating may be effected by brushing the mixture of finely divided particles over the face to be coated or, as shown, the base material in the form of a continuous web may be advanced through a falling curtain of the mixture 9 from vibrating hopper 8, prior to brushing with brush 10, advanced through a falling curtain of particles 12 from vibrating hopper 11, and under a forming roller 13 which may be ribbed or flat. The coated material is then passed through oven 14 to "case harden" the particulate layer, under finishing roller 15, which may be ribbed or flat, and through oven 16 to sinter the particles. Finely divided particles 19 from vibrating hopper 18 may be applied to the face of the sintered layer or to the non-coated face of the base material and after passing under brush 20, sintered, e.g. at 150-250 C., in oven 21, to form an adherent continuous lace-like network of abutting particles having interstices which constitute pores of regulated size. The diaphragm or separator may be impregnated with a wetting agent from spray 22 and dried in oven 23 prior to being cut by guillotine 24. Specification 843,452 is referred to.

54. 发明专利

AT71493B 未知
公开(公告)号：AT71493B
公开(公告)日：1916-04-10
申请号：AT71493D
申请日：1914-06-15
申请人： MICHAEL PAUL , LEIBIUS THEODOR
发明人： MICHAEL PAUL , LEIBIUS THEODOR

55. 发明专利

ES40566A1 Un procedimiento para la reparación y conservación de los tubos neumáticos. 未知
公开(公告)号：ES40566A1
公开(公告)日：1907-05-16
申请号：ES40566
申请日：1907-04-22
申请人： MAC NAMARA MICHAEL PAUL

56. 发明专利

GB190625975A An Improvement in Repair Devices for Pneumatic Tires. 未知
公开(公告)号：GB190625975A
公开(公告)日：1907-03-21
申请号：GB190625975D
申请日：1906-11-16
申请人： TRAVER PHILIP COOKINGHAM , MCNAMARA MICHAEL PAUL
发明人： TRAVER PHILIP COOKINGHAM , MCNAMARA MICHAEL PAUL
摘要： 25,975. Traver, P. C., and McNamara, M. P. Nov. 16. Tyres, pneumatic. - A repair band, which is inserted between the inner tube and cover, consists of a plate 5, of sheet metal or other rigid material, having a flange 10 for engagement with the heel 14 of the cover, and outwardly - turned edges 50 for taking into the c o v e r. Gripping- teeth 7 for preventing creeping are formed integrally with the band by punching and bending, or consist of through-pius secured by washers. The plate, which is shaped to the approximate contour of the inner tube and extends over the tread portion, may be provided with an inner lining of yielding sheet material arranged to overhang the edges 50; the liner is secured by the pins and washers, or otherwise.

57. 发明专利

FR371600A 未知
公开(公告)号：FR371600A
公开(公告)日：1907-03-11
申请号：FR371600D
申请日：1906-11-19
申请人： PHILIP COOKINGHAM TRAVER , MICHAEL PAUL MACNAMARA
发明人： TRAVER PHILIP COOKINGHAM , MACNAMARA MICHAEL PAUL
IPC分类号： B29C73/04

58. 发明专利

IL289523D0 Antibodies for binding psma with reduced affinity for the neonatal fc receptor 未知
公开(公告)号：IL289523D0
公开(公告)日：2022-03-01
申请号：IL28952321
申请日：2021-12-30
申请人： TELIX INT PTY LTD , MICHAEL PAUL WHEATCROFT , CHRISTIAN PETER BEHRENBRUCH
发明人： MICHAEL PAUL WHEATCROFT , CHRISTIAN PETER BEHRENBRUCH
IPC分类号： A61K39/00 , A61K51/10 , A61P35/00 , C07K16/30 , G01N33/534 , G01N33/60
摘要： The invention relates to anti-PSMA antibodies comprising a heavy chain constant region comprising one or more amino acid substitutions compared to a wild-type IgG, wherein the one or more amino acid substitutions reduce the affinity of the antibody for the neonatal Fc receptor (FcRn), thereby reducing the serum half-life of the modified antibody compared to a wild-type antibody of class IgG. The one or more amino acid modification having the effect of reducing FcRn binding is selected from positions His310, His433, His435, His436, Ile253. Antibodies of the present invention are particularly suited for use in radioimmunotherapy.

59. 发明专利

PL2981741T3 NAPĘDOWA PRZEKŁADNIA ZĘBATA 未知
公开(公告)号：PL2981741T3
公开(公告)日：2019-06-28
申请号：PL14733284
申请日：2014-04-01
申请人： GEISSLER MICHAEL PAUL ALEXANDER
发明人： GEISSLER MICHAEL PAUL ALEXANDER
IPC分类号： F16H57/12

60. 发明专利

PL2812509T3 PŁYTKA PODŁOGOWA 未知
公开(公告)号：PL2812509T3
公开(公告)日：2019-05-31
申请号：PL13707566
申请日：2013-02-07
申请人： HURSON RYAN PATRICK , VAN LEUSDEN EVERARDUS JOHANNES MARIA , ATKINS MICHAEL PAUL NICHOLAS
发明人： HURSON RYAN PATRICK
IPC分类号： E04F15/02 , E04F15/10

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