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51. 发明授权

US09554847B2 Real time assessment of ablation from electrocardiogram signals 有权
标题翻译：从心电图信号消融的实时评估
公开(公告)号：US09554847B2
公开(公告)日：2017-01-31
申请号：US13539628
申请日：2012-07-02
申请人： Assaf Govari , Athanassios Papaioannou
发明人： Assaf Govari , Athanassios Papaioannou
IPC分类号： A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/00357 , A61B2018/00577 , A61B2018/00708 , A61B2018/00839
摘要： An apparatus includes an intra-body probe and a processor. The intra-body probe includes an electrode, which is configured to contact tissue in a heart. The processor is configured to receive an electrical signal from the electrode, to distinguish a local component, due to the tissue with which the electrode is in contact, in the electrical signal from a remote-field contribution to the signal, and to control a therapeutic procedure applied to the tissue responsively to the distinguished local component.
摘要翻译：一种装置包括体内探针和处理器。体内探针包括被配置为接触心脏中的组织的电极。处理器被配置为从电极接收电信号，以区分由电极与电极接触的组织在局部组件的电信号中对来自对信号的远场贡献，并且控制治疗响应于识别的局部组分应用于组织的程序。

52. 发明授权

US09326700B2 Catheter display showing tip angle and pressure 有权
标题翻译：导管显示显示尖端角度和压力
公开(公告)号：US09326700B2
公开(公告)日：2016-05-03
申请号：US12342747
申请日：2008-12-23
申请人： Assaf Govari , Yaron Ephrath , Andres Claudio Altmann , Nahum Kilim
发明人： Assaf Govari , Yaron Ephrath , Andres Claudio Altmann , Nahum Kilim
IPC分类号： A61B18/14 , A61B5/05 , A61B5/06 , A61B5/00 , A61B19/00
CPC分类号： A61B5/06 , A61B5/062 , A61B5/6885 , A61B5/743 , A61B2034/2051
摘要： A method for displaying information includes receiving a measurement with respect to an invasive probe inside a body of a subject of at least one probe parameter, selected from a group of parameters consisting of a bend angle of the probe and a pressure on the probe. Responsively to the measurement, an icon is displayed on a display screen representing the at least one probe parameter for viewing by an operator of the probe.
摘要翻译：用于显示信息的方法包括接收关于选自由探头的弯曲角度和探针上的压力组成的参数组中的至少一个探针参数的受试者身体内的侵入探针的测量。响应于测量，在显示屏幕上显示表示用于由探头的操作者观看的至少一个探测参数的图标。

53. 发明授权

US09308041B2 Lasso catheter with rotating ultrasound transducer 有权
标题翻译： Lasso导管与旋转超声换能器
公开(公告)号：US09308041B2
公开(公告)日：2016-04-12
申请号：US12975787
申请日：2010-12-22
申请人： Andres Claudio Altmann , Assaf Govari
发明人： Andres Claudio Altmann , Assaf Govari
IPC分类号： A61B18/14 , A61B8/08 , A61B8/12 , A61B8/00 , A61B5/042 , A61B5/06 , A61B18/00 , A61B19/00 , A61M25/01
CPC分类号： A61B18/1492 , A61B5/0422 , A61B5/061 , A61B8/0883 , A61B8/12 , A61B8/445 , A61B2018/00375 , A61B2018/00577 , A61B2018/00839 , A61B2018/1435 , A61B2018/1467 , A61B2034/2051 , A61B2090/3784 , A61M2025/0163
摘要： A medical device includes an insertion shaft, having a longitudinal axis and having a distal end adapted for insertion into a body of a patient. A resilient end section is fixed to the distal end of the insertion shaft and is formed so as to define an arc oriented obliquely relative to the axis and having a center of curvature on the axis. One or more electrodes are disposed along the end section. An ultrasound transducer is fixed to the distal end and is configured to image a vicinity of the arc using ultrasound waves.
摘要翻译：医疗装置包括插入轴，其具有纵向轴线并且具有适于插入患者体内的远端。弹性端部固定到插入轴的远端，并且形成为限定相对于轴线倾斜定向并且在轴线上具有曲率中心的圆弧。沿着端部设置一个或多个电极。超声换能器被固定到远端，并被配置成使用超声波对弧的附近成像。

54. 发明授权

US09241632B2 Synchronization of wireless catheters 有权
公开(公告)号：US09241632B2
公开(公告)日：2016-01-26
申请号：US13186626
申请日：2011-07-20
申请人： Nahum Kilim , Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
发明人： Nahum Kilim , Assaf Govari , Andres Claudio Altmann , Yaron Ephrath
IPC分类号： A61B5/0402 , H04J3/06 , A61B5/00 , A61B5/042
CPC分类号： A61B5/0006 , A61B5/0015 , A61B5/0031 , A61B5/042 , A61B5/0422 , A61B5/6852 , H04J3/06 , H04J3/0635 , H04J3/0647 , H04J3/0658 , H04J3/0661 , H04J3/0667 , H04J3/0682 , H04L1/00 , H04L1/1671 , H04Q9/04 , H04Q2209/845
摘要： A method includes disposing multiple medical probes to acquire physiological data concurrently from a living body. The data is sent from the multiple medical probes by transmitting over wireless channels respective sequences of data packets that are marked with respective packet numbers. A synchronization signal that is broadcast to the multiple probes is received in the probes. In response to receiving the synchronization signal, the packet numbers that are to be assigned in the probes to subsequent data packets in the respective sequences are reset.

55. 发明授权

US08668686B2 Sensing contact of ablation catheter using differential temperature measurements 有权
标题翻译：使用差分温度测量的消融导管的感应接触
公开(公告)号：US08668686B2
公开(公告)日：2014-03-11
申请号：US12646165
申请日：2009-12-23
申请人： Assaf Govari , Christopher Thomas Beeckler , Athanassios Papaioannou
发明人： Assaf Govari , Christopher Thomas Beeckler , Athanassios Papaioannou
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B17/320068 , A61B18/20 , A61B2018/00011 , A61B2018/00797 , A61B2018/00821
摘要： Tissue ablation is carried out using insertion tube having at least one ablation electrode, a first temperature sensor disposed on the distal portion sufficiently proximate the ablation electrode to detect heat generated during the ablation procedure, a second temperature sensor disposed on the distal portion sufficiently distant from the ablation electrode to be unable to detect the heat, and electronic logic circuitry linked to the first temperature sensor and the second temperature sensor and programmed to compute a temperature differential between respective temperatures sensed by the first temperature sensor and the second temperature sensor when conveying the electromagnetic energy. Satisfactory contact status between the ablation electrode and the target tissue is indicated when the temperature differential exceeds a predetermined threshold.
摘要翻译：使用具有至少一个消融电极的插入管进行组织消融，第一温度传感器设置在足够接近消融电极的远侧部分上，以检测在消融过程期间产生的热量;第二温度传感器，设置在远端部分上所述消融电极不能检测到热量，以及连接到所述第一温度传感器和所述第二温度传感器的电子逻辑电路，并被编程为计算当传送所述第一温度传感器和所述第二温度传感器时检测到的各温度之间的温度差电磁能量。当温度差超过预定阈值时，指示消融电极与目标组织之间的良好的接触状态。

56. 发明申请

US20140051959A1 MACHINE LEARNING IN DETERMINING CATHETER ELECTRODE CONTACT 有权
标题翻译：机器学习确定导管电极接触
公开(公告)号：US20140051959A1
公开(公告)日：2014-02-20
申请号：US13589347
申请日：2012-08-20
申请人： Vadim Gliner , Assaf Govari
发明人： Vadim Gliner , Assaf Govari
IPC分类号： A61B18/14 , A61B5/053
CPC分类号： A61B18/1492 , A61B5/0422 , A61B5/0538 , A61B5/6852 , A61B5/6869 , A61B5/6885 , A61B5/7267 , A61B2017/00026 , A61B2017/00044 , A61B2017/00243 , A61B2018/00357 , A61B2018/00577 , A61B2018/00666 , A61B2018/0069 , A61B2018/00869 , A61B2018/00875 , A61B2018/00904 , A61B2018/00988 , A61B2034/2051 , A61B2090/065
摘要： Cardiac catheterization is carried out by memorizing a designation of a contact state between an electrode of the probe and the heart wall as one of an in-contact state and an out-of-contact state, and making a series of determinations of an impedance phase angle of an electrical current passing through the electrode and another electrode, identifying maximum and minimum phase angles in the series, and defining a binary classifier adaptively as midway between the extremes. A test value is compared to the classifier as adjusted by a hysteresis factor, and a change in the contact state is reported when the test value exceeds or falls below the adjusted classifier.
摘要翻译：通过将探针的电极和心壁之间的接触状态的指定记为接触状态和非接触状态之一进行心脏导管插入，并进行一系列阻抗相位的确定通过电极和另一个电极的电流的角度，识别该系列中的最大和最小相位角，并自适应地定义二极分类器作为极端之间的中间点。将测试值与由滞后因子调整的分类器进行比较，并且当测试值超过或低于调整分类器时报告接触状态的变化。

57. 发明授权

US08641708B2 Measuring weak signals over ablation lines 有权
标题翻译：测量消融线上的弱信号
公开(公告)号：US08641708B2
公开(公告)日：2014-02-04
申请号：US12648327
申请日：2009-12-29
申请人： Assaf Govari , Yaron Ephrath
发明人： Assaf Govari , Yaron Ephrath
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2017/00084 , A61B2018/00357 , A61B2018/00821
摘要： A medical probe, including an ablation electrode and a first conductor connected to the ablation electrode. The first conductor is configured to convey ablation energy to the ablation electrode. The probe also includes a second conductor which is connected at a junction to the first conductor so as to form a thermocouple at the junction.
摘要翻译：医疗探针，包括消融电极和连接到消融电极的第一导体。第一导体被配置为将消融能量传送到消融电极。该探头还包括一个第二导体，该第二导体在一个结处连接到该第一导体，以便在该结处形成热电偶。

58. 发明申请

US20140005526A1 CATHETER WITH SYNTHETIC APERTURE MRI SENSOR 审中-公开
标题翻译：具有合成孔径MRI传感器的导管
公开(公告)号：US20140005526A1
公开(公告)日：2014-01-02
申请号：US13539524
申请日：2012-07-02
申请人： Assaf Govari , Andres Claudio Altmann , Yitzhack Schwartz , Yaron Ephrath , Christopher Thomas Beeckler
发明人： Assaf Govari , Andres Claudio Altmann , Yitzhack Schwartz , Yaron Ephrath , Christopher Thomas Beeckler
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/0044 , A61B5/6852 , G01R33/3415 , G01R33/3621
摘要： A medical probe, including a flexible insertion tube having a distal end for insertion into a body cavity. An array of spatially separated coils is positioned within the distal end. A processor is configured to process respective signals generated by the coils in response to magnetic resonance of tissue in the body cavity, and to process the signals while applying a phase delay responsive to a separation between the coils so as to image the tissue.
摘要翻译：一种医疗探针，包括具有用于插入体腔的远端的柔性插入管。空间分离线圈的阵列位于远端内。处理器被配置为响应于体腔中的组织的磁共振来处理由线圈产生的相应信号，并且响应于线圈之间的间隔而施加相位延迟来处理信号，以便对组织进行成像。

59. 发明申请

US20130131489A1 CATHETER WITH BENDABLE TIP 有权
公开(公告)号：US20130131489A1
公开(公告)日：2013-05-23
申请号：US13470842
申请日：2012-05-14
申请人： Assaf Govari , Andres Claudio Altmann , Ariel Garcia
发明人： Assaf Govari , Andres Claudio Altmann , Ariel Garcia
IPC分类号： A61B18/14 , A61B5/05
CPC分类号： A61B18/1492 , A61B5/05 , A61B5/062 , A61B5/6851 , A61B5/6852 , A61B17/00234 , A61B18/14 , A61B34/20 , A61B2017/00243 , A61B2017/00309 , A61B2017/00526 , A61B2017/00862 , A61B2018/00357 , A61B2034/2051 , A61B2090/0811 , A61M25/0082 , A61M2025/0081 , Y10T29/49826
摘要： A medical probe includes a flexible insertion tube, having a distal end for insertion into a body cavity of a patient, and a distal tip, which is disposed at the distal end of the insertion tube and is configured to be brought into contact with tissue in the body cavity. A coupling member couples the distal tip to the distal end of the insertion tube and includes a tubular piece of an elastic material having a helical cut therethrough along a portion of a length of the piece.

60. 发明授权

US08401624B2 ECG signal analysis tool 有权
标题翻译：心电信号分析工具
公开(公告)号：US08401624B2
公开(公告)日：2013-03-19
申请号：US12327267
申请日：2008-12-03
申请人： Assaf Govari
发明人： Assaf Govari
IPC分类号： A61B5/04 , A61B5/02
CPC分类号： A61B5/04525 , G06K9/00523
摘要： A computer-implemented method for analyzing a physiological signal includes selecting a first time interval containing a pattern of interest in a recording of the physiological signal. Respective values of a characteristic of the physiological signal are computed in a plurality of time segments within the first time interval. The computed values are concatenated to form a signature of the pattern of interest. A further occurrence of the pattern of interest is identified in the physiological signal during a second time interval by matching the signal in the second time interval to the signature.
摘要翻译：用于分析生理信号的计算机实现的方法包括在生理信号的记录中选择包含感兴趣的模式的第一时间间隔。在第一时间间隔内的多个时间段中计算生理信号的特征的相应值。计算的值被连接以形成感兴趣的模式的签名。通过将第二时间间隔中的信号与签名相匹配，在第二时间间隔期间在生理信号中识别感兴趣的模式的进一步出现。

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