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51. 发明申请

WO2016157184A1 ALL-OPTICAL SINGLE-ATOM PHOTON ROUTER CONTROLLED BY A SINGLE PHOTON 审中-公开
标题翻译：全光子单光子路由器由单光子控制
公开(公告)号：WO2016157184A1
公开(公告)日：2016-10-06
申请号：PCT/IL2016/050339
申请日：2016-03-30
申请人： YEDA RESEARCH AND DEVELOPMENT CO. LTD.
发明人： DAYAN, Barak , SHOMRONI, Itay , ROSENBLUM, Serge
IPC分类号： B82Y20/00 , G02B6/35 , G02F1/01
CPC分类号： G11C13/04 , B82Y20/00 , G02B6/2746 , G02B6/35 , G02F1/01 , G02F1/0126 , G02F1/3521 , G02F2203/15 , G11C7/005
摘要： A switch activated by a single control photon for routing a single target photon from either of two switch inputs to either of two switch outputs. The device is based on a single quantum emitter, such as an atom, coupled to a fiber-coupled, chip-based optical micro-resonator. A single reflected control photon toggles the switch from high reflection to high transmission mode, with no additional control fields required. The control and target photons are both in-fiber and practically identical, for compatibility with scalable architectures for quantum information processing.
摘要翻译：由单个控制光子激活的开关，用于将单个目标光子从两个开关输入中的任一个路由到两个开关输出中的任一个。该器件基于耦合到光纤耦合的基于芯片的光学微谐振器的单个量子发射器，例如原子。单反射控制光子将开关从高反射切换到高透射模式，无需额外的控制场。控制和目标光子都是光纤内和实际上相同的，以便与用于量子信息处理的可扩展架构兼容。

52. 发明申请

WO2015128868A1 BIOCIDAL COMPOSITION, PREPARATION AND METHODS OF USE THEREOF 审中-公开
标题翻译：生物组合物，其制备方法及其使用方法
公开(公告)号：WO2015128868A1
公开(公告)日：2015-09-03
申请号：PCT/IL2015/050218
申请日：2015-02-26
申请人： BROMINE COMPOUNDS LTD.
发明人： ANTEBI, Shlomo , FELDMAN, David
IPC分类号： A61L2/16 , A01N43/64 , A01N33/14
CPC分类号： A01N43/64 , A01N59/00 , A61L2/18 , A61L2/23 , A01N25/22
摘要： This invention is directed to a biocidal, antifouling or disinfection composition and methods of use thereof for inhibiting growth of microorganism and biofilms, reducing the microbial activity and killing microorganism in an aqueous system or on solid surfaces, wherein the biocidal composition includes stabilized chlorine compound such as dichloroisocyanurate salt, ammonium salt and a base.
摘要翻译：本发明涉及杀生物，防污或消毒组合物及其用于抑制微生物和生物膜生长的方法，降低微生物活性并杀死水系统或固体表面上的微生物，其中杀生物组合物包括稳定的氯化合物作为二氯异氰尿酸盐，铵盐和碱。

53. 发明申请

WO2022149126A2 PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL 审中-公开
公开(公告)号：WO2022149126A2
公开(公告)日：2022-07-14
申请号：PCT/IL2022/050009
申请日：2022-01-03
申请人： O.Y.M. INNOVATION LTD. , BAR ILAN UNIVERSITY
发明人： MARGEL, Shlomo , STEINMETZ, Hanna , GELBER, Chen , GOLDSTEIN, Yarden
IPC分类号： A61K8/25 , A61K8/41 , A61K8/55 , A61Q11/00 , A61K2800/412 , A61K2800/413 , A61K2800/622 , A61K2800/651 , A61K31/198 , A61K31/66 , A61K31/663 , A61P1/02 , A61P31/04 , A61Q11/02 , C07F9/3839 , C07F9/3869
摘要： Provided herein are compositions and methods comprising phosphonates, N-halamines or combination thereof for dental care. Specifically, for removing tartar (calculus), including mature tartar.

54. 发明申请

WO2020174480A1 COATING COMPRISING ANTI-MICROBIAL PARTICLES, METHODS OF PREPARATION AND USES THEREOF 审中-公开
公开(公告)号：WO2020174480A1
公开(公告)日：2020-09-03
申请号：PCT/IL2020/050231
申请日：2020-02-27
申请人： NOBIO LTD.
发明人： ZALTSMAN, Nathan , WEISS, Ervin Itzhak , DAVID, Dganit
IPC分类号： A61K31/14 , A61K31/205 , A61K31/4425 , A61P31/04 , A61F2/00 , C09D183/00
摘要： This invention relates to coatings comprising anti-microbial particles, methods of preparation and uses thereof.

55. 发明申请

WO2019220430A2 LASER BEAMS METHODS AND SYSTEMS 审中-公开
公开(公告)号：WO2019220430A2
公开(公告)日：2019-11-21
申请号：PCT/IL2019/050536
申请日：2019-05-13
申请人： CIVAN ADVANCED TECHNOLOGIES, LTD
发明人： VIDNE, Yaniv , URBACH, Benayahu , VERED, Ran , JACKEL, Steven Michael , ALBECK, Yishai , GROSS, Ziv , BOUBLI, Avraham , TELLER, Gabriel , SHEKEL, Eyal
IPC分类号： H01S3/091
摘要： Methods and apparatuses for manipulating and modulating of laser beams. The methods and apparatuses enable activating and deactivating of laser beams, while the laser systems maintain their operating power. Further, a hybrid pump module configured to be coupled to an optical fiber having a core and at least one clad, comprising: at least one focusing lens in optical with the optical fiber; plurality of diode modules, each configured to output a multi-mode beam in optical path with the clad; and at least one core associated module, in optical path with the core, configured to provide selected functions. Further, apparatus and methods configured for frequency doubling of optical radiation.

56. 发明申请

WO2019038758A1 COMBINATION IMMUNE THERAPY AND CYTOKINE CONTROL THERAPY FOR CANCER TREATMENT 审中-公开
公开(公告)号：WO2019038758A1
公开(公告)日：2019-02-28
申请号：PCT/IL2018/050916
申请日：2018-08-20
申请人： ENLIVEX THERAPEUTICS LTD
发明人： NOVIK, Shai , MEVORACH, Dror
IPC分类号： A61K35/15 , A61K35/17 , A61P37/06
摘要： Compositions disclosed herein, and methods of use thereof included those for inhibiting or reducing the incidence of cytokine release syndrome or cytokine storm in a subject undergoing CAR T-cell therapy, methods of treating a cancer or tumor, methods of reducing tumor load, methods of reducing the size or growth rate of a cancer or a tumor, and methods of extending of the survival of a subject suffering from a cancer or tumor, wherein the subjects are administered compositions comprising apoptotic cells or apoptotic cell supernatants. Compositions and methods of use thereof may increase the efficacy of a CAR T-cell cancer therapy. Disclosed herein are also compositions and methods of use thereof for decreasing or inhibiting cytokine production in a subject experiencing cytokine release syndrome or cytokine storm. In certain instances compositions may include additional chemotherapeutic or immunomodulatory agents.

57. 发明申请

WO2018207179A1 TRANSDIFFERENTIATED CELL POPULATIONS AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：WO2018207179A1
公开(公告)日：2018-11-15
申请号：PCT/IL2018/050496
申请日：2018-05-08
申请人： ORGENESIS LTD. , TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
发明人： FERBER, Sarah
IPC分类号： C12N15/09 , C12N15/861 , C12N5/10 , A61K35/39
摘要： Disclosed herein are methods for manufacturing transdifferentiated populations of non-pancreatic human insulin producing cells, and methods for enriching populations of non-pancreatic β- cells for cells comprising an enriched capacity for transcription factor- induced transdifferentiation into a pancreatic β-cell phenotype and function.

58. 发明申请

WO2018061001A3 THERMOELECTRIC DEVICE BASED ON DIODES 审中-公开
标题翻译：基于二极管的热电器件
公开(公告)号：WO2018061001A3
公开(公告)日：2018-04-05
申请号：PCT/IL2017/051091
申请日：2017-09-28
申请人： YEDA RESEARCH AND DEVELOPMENT CO. LTD.
发明人： IMRY, Yoseph , SHAHAR, Dan
IPC分类号： H01L35/34 , G01R31/26
摘要： Thermoelectric devices based on diodes. Devices and systems can be used as cooling devices or cooling systems or as energy harvesting devices or energy harvesting systems. System comprising: a diode (3.1) comprising a first end and a second end; at least one thermometer (3.2) attached to said first end of said diode; and a power supply/current generator (3.6). Method of changing the temperature of an element, said method comprising: providing a system comprising:a diode comprising a first end and a second end; a thermometer attached to at least said first end or said second end of said diode; and a power supply/current generator; contacting said first end or said second end of said diode to said element; driving current through or applying voltage to said diode, thereby cooling the first end of said diode and heating the second end of said diode, thereby transferring heat between said diode and said element, thus changing the temperature of said element.
摘要翻译：
基于二极管的热电器件。设备和系统可以用作冷却设备或冷却系统，或用作能量收集设备或能量收集系统。系统包括：二极管（3.1），其包括第一端和第二端; 至少一个温度计（3.2），连接到所述二极管的所述第一端; 和电源/电流发生器（3.6）。改变元件的温度的方法，所述方法包括：提供一种系统，所述系统包括：包括第一端和第二端的二极管; 连接到所述二极管的至少所述第一端或所述第二端的温度计; 和电源/电流发生器; 使所述二极管的所述第一端或所述第二端接触所述元件; 通过驱动电流或向所述二极管施加电压，从而冷却所述二极管的第一端并加热所述二极管的第二端，从而在所述二极管和所述元件之间传递热量，从而改变所述元件的温度。

59. 发明申请

WO2018047183A1 COMPOSITIONS AND METHODS FOR REGULATING GENE EXPRESSION FOR TARGETED MUTAGENESIS 审中-公开
标题翻译：调节靶向致突变基因表达的组合物和方法
公开(公告)号：WO2018047183A1
公开(公告)日：2018-03-15
申请号：PCT/IL2017/051020
申请日：2017-09-11
申请人： YEDA RESEARCH AND DEVELOPMENT CO. LTD.
发明人： AHARONI, Asaph , BOCOBZA, Samuel , DAHAN, Tal
IPC分类号： C12N15/82 , C07K14/415
摘要： Methods of increasing targeted mutagenesis in a plant and recombinant nucleic acid molecules used in these methods are described herein. Recombinant nucleic acid molecules have nucleic acid sequences selected from those 5' and 3' of regions adjacent to nucleic acid sequence encoding a POLYUBIQUITIN10 gene, wherein the recombinant nucleic acid molecule further includes a multiple cloning site or a target gene.
摘要翻译：本文描述了增加植物中靶向诱变的方法和这些方法中使用的重组核酸分子。重组核酸分子具有选自与编码POLYUBIQUITIN10基因的核酸序列相邻的区域的5'和3'的核酸序列，其中重组核酸分子还包含多克隆位点或靶基因。

60. 发明申请

WO2017145142A1 MICRO AND NANOPARTICULATE COMPOSITIONS COMPRISING ANTI-MICROBIALLY ACTIVE GROUPS 审中-公开
标题翻译：包含抗微生物活性基团的微粒和纳米微粒组合物
公开(公告)号：WO2017145142A1
公开(公告)日：2017-08-31
申请号：PCT/IL2016/050219
申请日：2016-02-25
申请人： NOBIO LTD. , HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
发明人： ZALTSMAN, Nathan , WEISS, Ervin, Itzhak , BEYTH, Nurit
IPC分类号： C11D1/62 , A61P31/04 , C11D1/40 , A01N25/12 , B82B1/00
CPC分类号： A01N33/12 , A61K47/6923 , A61K47/6929 , A61L17/00 , A01N25/12
摘要： The present invention relates to anti-microbially active micro and nanoparticles, compositions comprising same, and use thereof for inhibiting bacterial growth on surfaces or devices, e.g., dental surfaces or devices. The present invention further discloses methods of making such anti-microbially active micro or nanoparticles.
摘要翻译：本发明涉及抗微生物活性微米颗粒和纳米颗粒，包含其的组合物，以及其用于抑制表面或装置（例如牙齿表面或装置）上的细菌生长的用途。本发明进一步公开了制造这种抗微生物活性微米或纳米颗粒的方法。

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