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    • 51. 发明申请
    • A PHOTONIC RESONANT MOTOR
    • WO2018087789A8
    • 2018-05-17
    • PCT/IT2017/000111
    • 2017-06-01
    • QOPSYS S.r.l.
    • CAMPANELLA, Carlo Edoardo
    • G02B6/12G02B6/293
    • A photonic motor is disclosed that comprises: at least one optical radiation input; a first optical waveguides arrangement, including at least one first optical resonator lying in a first plane to form a static part of the motor in a predetermined coordinate reference system; an excitation optical waveguides arrangement coupled to the first optical waveguides arrangement at a predetermined optical mode coupling distance to the at least one first optical resonator and configured to receive at least one optical radiation of predetermined wavelength from the at least one optical radiation input and to optically couple the optical radiation to the at least one first optical resonator; at least a second optical waveguides arrangement, including at least one second optical resonator lying in a second plane parallel to the first plane at a predetermined stacking distance perpendicular to the planes, the second optical waveguides arrangement being configured to move in the second plane with respect to the first optical waveguides arrangement according to at least a predefined direction of movement, so as to form a moving part of the motor in the predetermined coordinate reference system, wherein the stacking distance is adapted to establish an evanescent-wave coupling of optical modes between at least one first optical resonator of the first optical waveguides arrangement and at least one second optical resonator of the second optical waveguides arrangement, in a proximity condition of the first and second optical resonator in a plane transversal to the first and second plane where local motion of the second arrangement occurs, the first and second optical resonator being adapted to guide at least one resonant symmetric mode at a predetermined first wavelength or at least one resonant anti-symmetric mode at a predetermined second wavelength or at least a combination or superposition of at least one resonant symmetric mode at a predetermined first wavelength and at least one resonant anti-symmetric mode at a predetermined second wavelength, as a function of the stacking distance as well as of the distance between the first and second optical resonator on the transversal plane, and wherein, when a resonant symmetric mode is selectively established, an attractive condition of the second optical resonator towards the first optical resonator is established that generates, on the second plane, a motion of approach of the second optical resonator towards the first optical resonator according to the predefined local direction of movement, or, when a resonant anti-symmetric mode is selectively established, a repulsive condition of the second optical resonator from the first optical resonator is established, that generates on the second plane a motion of departure of the second optical resonator from the first optical resonator according to the predefined local direction of movement.
    • 53. 发明申请
    • METHOD OF PRENATAL DIAGNOSIS
    • 临床诊断方法
    • WO2015181718A1
    • 2015-12-03
    • PCT/IB2015/053926
    • 2015-05-26
    • EBIOS FUTURA S.R.L.
    • BENELLI, MatteoGERUNDINO, FrancescaGIACHINI, ClaudiaPESCUCCI, Chiara
    • C12Q1/68G06F19/18G06F19/22G06F19/24
    • C12Q1/6869C12Q2537/159C12Q2537/16C12Q2537/165G06F19/18G06F19/22G06F19/24
    • Method of prenatal diagnosis comprising the steps of: acquiring (1) reads of fragments of genomic libraries obtained from circulating free total DNA in a sample of maternal plasma, the DNA representing a plurality of chromosomes; aligning (2) the reads with respect to a predetermined reference genome obtaining a first dataset (SAM); converting (4) the first dataset (SAM) into a second dataset (BAM) so as to allow sorting thereof according to chromosomal coordinates and successive duplicate removal, obtaining a third dataset containing all the reads aligned and devoid of duplicates; subdividing (6) at least one chromosome into windows of predetermined dimensions, so as to count the reads which have a "mapping validity" greater than or equal to a threshold value in each reading window, obtaining a total number of above-threshold reads (N W ); normalizing, for each reading window, the total number of above-threshold reads (N W ) with respect to the total number (N tot ) of reads of the fragment of genomic library obtaining a first normalized datum (N W,lib ); normalizing (8), for each reading window, the first normalized datum (N W,lib ) with respect to a systematic error due to the content of G and C bases, obtaining a second normalized datum (N W,lib,GC ); calculating (10), for each chromosome, a median of all the second normalized data (N W,lib,GC ) obtaining a final value (N ji ); calculating (12) an aneuploidy parameter (Z) for at least one chromosome; determining the aneuploidy parameter (Z) of at least one chromosome so as to evaluate whether the sample of maternal plasma is aneuploid.
    • 产前诊断方法,包括以下步骤:(1)读取母体血浆样本中循环游离总DNA获得的基因组文库片段,DNA代表多条染色体; 对准(2)相对于获得第一数据集(SAM)的预定参考基因组的读取; 将所述第一数据集(SAM)转换(4)到第二数据集(BAM)中,以便根据染色体坐标和连续的重复删除来对其进行排序,获得包含所有对齐和没有重复的读出的第三数据集; 将至少一个染色体(6)细分为预定尺寸的窗口,以便对每个阅读窗口中具有大于或等于阈值的“映射有效性”的读数进行计数,获得高于阈值读数的总数( NW); 归一化,对于每个阅读窗口,相对于获得第一标准化数据(NW,lib)的基因组文库的片段的读数的总数(Ntot)的阈值读数(NW)的总数; 对于每个阅读窗口,归一化(8)关于由于G和C基数的内容导致的系统误差的第一归一化数据(NW,lib),获得第二归一化数据(NW,lib,GC); 对于每个染色体,计算(10)所有第二归一化数据(NW,lib,GC)的中值,获得最终值(Nji); 计算(12)至少一个染色体的非整倍体参数(Z); 确定至少一条染色体的非整倍性参数(Z),以评估母体血浆样品是否为非整倍体。
    • 54. 发明申请
    • AN AUTOMATED ADAPTIVE MAINTENANCE METHOD AND SYSTEM FOR WELDING GUN ELECTRODES
    • 一种用于焊接电极的自动自适应维护方法和系统
    • WO2015036038A1
    • 2015-03-19
    • PCT/EP2013/069034
    • 2013-09-13
    • SINTERLEGHE S.R.L.
    • BARTLETT, VincentSMITH, SullivanWOLOSZYN, Andrew
    • B23K11/30B23K11/25B23K11/11
    • B23K11/3063B23K11/11B23K11/25
    • An automated adaptive maintenance method and system for welding gun electrodes An automated welding electrode adaptive maintenance method and system are disclosed, including: - acquiring a predetermined electrode maintenance schedule, including electrode maintenance parameters; - acquiring welding electrode parameters representative of a wear condition of at least one electrode at a predetermined maintenance frequency; - selecting a maintenance operation for at least one electrode based on the comparison of the electrode parameters representative of the wear condition of at least one electrode with predetermined reference parameters; - issuing a signal to a selected maintenance station for performing the selected maintenance operation; and - controlling adjusting the electrode maintenance frequency based on the electrode parameters representative of the wear condition of at least one electrode.
    • 一种用于焊接枪电极的自动适应性维护方法和系统公开了一种自动焊接电极自适应维护方法和系统,包括: - 获取包括电极维护参数的预定电极维护计划; - 获取代表在预定维护频率下的至少一个电极的磨损状况的焊接电极参数; - 基于代表至少一个电极的磨损状况的电极参数与预定参考参数的比较来选择至少一个电极的维护操作; - 向所选择的维护站发出信号以执行所选择的维护操作; 以及 - 基于代表至少一个电极的磨损状况的电极参数来控制电极维持频率的调节。
    • 56. 发明申请
    • MODULAR ROOF SYSTEM FOR A BUILDING
    • 用于建筑的模块化屋顶系统
    • WO2012101486A1
    • 2012-08-02
    • PCT/IB2011/055646
    • 2011-12-13
    • VASS TECHNOLOGIES S.R.L.GIANOLIO, Giuseppe
    • GIANOLIO, Giuseppe
    • E04D3/35F24J2/04H01L31/048E04B7/22
    • E04B7/22E04D3/351E04D3/357E04D3/358H02S20/23Y02A30/62Y02B10/12Y02B10/20Y02E10/50Y10T29/49623
    • A modular roof system for a building is described, said system comprising a plurality of roofing modules (M) which are designed to be arranged alongside each other substantially with continuity on a supporting structure (C, T), wherein each roofing module (M) comprises a supporting base (20; 120) which is designed to receive at least one functional element of the roofing and rests on the support structure (C, T) in an installation condition, and a top covering part (22; 122) supported on the base (20; 120). The base (20; 120) is shaped so as to define at least one free channel (26'; 126') extending substantially along a first direction of juxtaposition of the modules (M) and each roofing module (M) has interlocking joining means for joining together with adjacent modules (M) along at least one direction of juxtaposition of the modules (M). A method for installing a modular roof system comprises: - executing a method for configuring the building roof, including determining the number of roofing modules (M) depending on the surface dimensions of the roof pitches and selecting a plurality of roofing modules (M) equipped with functional devices; - laying the selected roofing modules (M) according to the configuration method; - laying a network for connecting together the functional devices of the roofing modules along the service channels (40) in a predetermined covering direction of the roof; and - carrying out at least one procedure for testing the set of functional devices present.
    • 描述了一种用于建筑物的模块化屋顶系统,所述系统包括多个屋顶模块(M),其被设计成彼此大致连续布置在支撑结构(C,T)上,其中每个屋顶模块(M) 包括支撑基座(20; 120),所述支撑基座被设计成在安装状态下容纳至少一个所述屋顶的功能元件并且支撑在所述支撑结构(C,T)上;以及顶部覆盖部分(22; 122) 基座(20; 120)。 底座(20; 120)成形为限定至少一个沿着模块(M)的并置的第一方向延伸的至少一个自由通道(26'; 126'),并且每个屋顶模块(M)具有互锁联接装置 用于沿着模块(M)并置的至少一个方向与相邻模块(M)连接在一起。 一种用于安装模块化屋顶系统的方法包括: - 执行一种用于配置建筑物屋顶的方法,包括根据屋顶间距的表面尺寸确定屋顶模块(M)的数量,并选择装备的多个屋顶模块(M) 与功能设备; - 根据配置方法铺设选定的屋顶模块(M); - 铺设网络,用于沿屋顶的预定覆盖方向沿着服务通道(40)将屋顶模块的功能装置连接在一起; 以及 - 执行至少一个程序来测试存在的功能设备。