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41. 发明申请

US20090292157A1 Radiation Shielded Syringe Assembly and Uses Thereof 审中-公开
标题翻译：辐射屏蔽注射器组件及其用途
公开(公告)号：US20090292157A1
公开(公告)日：2009-11-26
申请号：US12374051
申请日：2007-07-12
申请人： John K. Bruce , Frank M Fago
发明人： John K. Bruce , Frank M Fago
IPC分类号： A61M36/08
CPC分类号： A61M5/1785 , A61M2005/312 , A61M2005/3128 , G21F5/018
摘要： The application relates to radiation shielding (12) for use with radiopharmaceutical syringes (14). For example, in at least some regards, the invention relates to a syringe radiation shield that includes a sleeve (18) having a syringe receptacle defined therein to accommodate a barrel (26) of the syringe. In addition, this syringe radiation shield may also include a cover (20) having a plunger receptacle defined therein to accommodate a plunger of the syringe. The sleeve and the cover may be removably coupled with one another so that the syringe can be housed within the syringe radiation shield, for example, during administration of a radiopharmaceutical from the syringe.
摘要翻译：本申请涉及用于放射性药物注射器（14）的辐射屏蔽（12）。例如，至少在某些方面，本发明涉及一种注射器辐射屏蔽，其包括具有限定在其中的注射器容器的套筒（18），以容纳注射器的筒体（26）。此外，该注射器辐射屏蔽还可以包括具有限定在其中的柱塞接收器以容纳注射器的柱塞的盖（20）。套筒和盖可以彼此可拆卸地联接，使得注射器可以容纳在注射器辐射屏蔽内，例如在从注射器施用放射性药物期间。

42. 发明授权

US07498595B2 Positron radioactive drug radiation shielding device 有权
标题翻译：正电子放射性药物辐射屏蔽装置
公开(公告)号：US07498595B2
公开(公告)日：2009-03-03
申请号：US11258015
申请日：2005-10-26
申请人： Chi-Kuang Chen
发明人： Chi-Kuang Chen
IPC分类号： G21F5/018 , A61M36/08
CPC分类号： G21F5/018 , G21Y2002/201 , G21Y2002/301 , G21Y2004/30
摘要： The present invention provides an improved positron radioactive drug radiation shielding device, which achieves savings in space required to store a canister after dismantling the device. Furthermore, a tungsten sleeve is disposed within the canister, and functions in coordination with a syringe. The tungsten sleeve is able to block radioactive radiation released by radioactive drugs contained in the syringe. Moreover, a front cover and a rear cover joined to two sides of the canister enable a hermetically-sealed space to be formed within the canister, which increases the effectiveness of blocking the amount of radiation from the canister, thereby reducing danger to the human body from the radiation.
摘要翻译：本发明提供一种改进的正电子放射性药物辐射屏蔽装置，其在拆卸装置之后实现储存罐所需的空间。此外，钨套筒设置在罐内，并且与注射器配合起作用。钨套筒能够阻挡注射器中放射性药物释放的放射性辐射。此外，连接到罐的两侧的前盖和后盖能够在罐内形成气密密封的空间，这增加了阻挡来自罐的辐射量的有效性，从而减少对人体的危害从辐射。

43. 发明申请

US20050224728A1 Packaging system for radioactive materials 有权
标题翻译：放射性物质包装系统
公开(公告)号：US20050224728A1
公开(公告)日：2005-10-13
申请号：US10966490
申请日：2004-10-15
申请人： Uwe Schwarz , Joachim Kahl
发明人： Uwe Schwarz , Joachim Kahl
IPC分类号： A61M36/08 , G21F5/018 , A61L15/00 , G21F5/00
CPC分类号： G21F5/018 , G21Y2002/304 , G21Y2002/501 , G21Y2004/303 , G21Y2004/304
摘要： Packaging system for radioactive materials having: a vial with closure for accommodating the radioactive material; a first casing to be opened, enclosing the vial, and essentially made from a transparent material, which has a capture cross-section selected for shielding at least a part of the emitted radiation; and a second casing to be opened, made from a material with a high capture cross-section (Z) for essentially shielding the remaining radiation, the second casing enclosing the first casing.
摘要翻译：用于放射性物质的包装系统，具有：具有用于容纳放射性物质的封闭物的小瓶; 要打开的第一套管，包围小瓶，并且基本由透明材料制成，其具有被选择用于屏蔽所发射的辐射的至少一部分的捕获截面; 以及由具有高捕获截面（Z）的材料制成的用于基本上屏蔽剩余辐射的待打开的第二壳体，所述第二壳体包围所述第一壳体。

44. 发明授权

US10016618B2 Methods and systems for integrated radiopharmaceutical generation, preparation, transportation and administration 有权
公开(公告)号：US10016618B2
公开(公告)日：2018-07-10
申请号：US15142000
申请日：2016-04-29
申请人： BAYER HEALTHCARE LLC
发明人： Alan D. Hirschman , Arthur E. Uber, III , David M. Reilly , John F. Kalafut , Frederick W. Trombley, III , Steven J. Remis , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths , Marc A. Mabie , Mark Trocki
IPC分类号： A61B6/00 , A61M36/06 , A61M36/08 , A61N5/10 , A61B6/03 , A61B6/04 , A61M5/172 , G06F19/00 , G21G4/08 , A61B6/10 , A61B5/055 , G21F5/015 , A61B5/0205 , A61B5/00 , A61M5/00 , A61M5/145 , A61M5/168 , A61M5/178
CPC分类号： A61N5/1001 , A61B5/0205 , A61B5/055 , A61B5/7289 , A61B6/032 , A61B6/037 , A61B6/0478 , A61B6/107 , A61B6/4057 , A61B6/4258 , A61B6/4423 , A61B6/507 , A61B6/508 , A61B6/5288 , A61B6/548 , A61M5/007 , A61M5/14546 , A61M5/1456 , A61M5/16827 , A61M5/16881 , A61M5/1723 , A61M5/1785 , A61M2205/3576 , A61N5/1071 , A61N2005/1021 , A61N2005/1094 , G06F19/3468 , G16H20/17 , G21F5/015 , G21G4/08
摘要： An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

45. 发明申请

US20110028775A1 THERAPEUTIC INFUSION AND TRANSFER SYSTEM FOR USE WITH RADIOACTIVE AGENTS 审中-公开
标题翻译：用于放射性药物的治疗输入和转移系统
公开(公告)号：US20110028775A1
公开(公告)日：2011-02-03
申请号：US12678670
申请日：2008-09-15
申请人： Norman Lafrance , Miguel De La Guardia
发明人： Norman Lafrance , Miguel De La Guardia
IPC分类号： A61M36/08
CPC分类号： A61M5/142 , A61M2205/75
摘要： Described herein are infusion systems and methods for delivering a radiopharmaceutical agent to a subject without exposing an administering health care professional to a potentially deleterious amount of radiation.
摘要翻译：本文描述的输注系统和方法用于将放射性药剂递送到受试者，而不会使管理卫生保健专业人员暴露于潜在有害量的辐射。

46. 发明申请

US20080177126A1 Radiopharmaceutical administration methods, fluid delivery systems and components thereof 有权
标题翻译：放射性药物给药方法，流体输送系统及其组分
公开(公告)号：US20080177126A1
公开(公告)日：2008-07-24
申请号：US11981429
申请日：2007-10-31
申请人： Leon J. Tate , James H. Shigeno , Steven C. Rygg , Jared E. Neff , Scott R. Griffith , Joseph E. Bisegna , Edward Ilgenfritz , Paul J. Miller , Scott Yanke
发明人： Leon J. Tate , James H. Shigeno , Steven C. Rygg , Jared E. Neff , Scott R. Griffith , Joseph E. Bisegna , Edward Ilgenfritz , Paul J. Miller , Scott Yanke
IPC分类号： A61M36/08
CPC分类号： A61M5/172 , A61K51/00 , A61M5/007 , A61M5/14 , A61M5/16822 , A61M5/3146 , A61M2005/1402 , G06F19/3468 , G16H20/17
摘要： A fluid path set for a fluid delivery system includes a tube coil that is designed to optimally position one or more volumes of a pharmaceutical within an ionization chamber to optimally measure and prepare a pharmaceutical dose for administration to a patient. The tube coil may be maintained in a desired dimensional geometry by means of a core structure around which the tube coil is positioned. Novel developments in radiopharmaceutical administration methods and systems include, but are not limited to, the configuration and layout of a fluid path set for use in a fluid delivery system, arrangements for piercing and drawing fluid from a pharmaceutical container (such as a vial), arrangements for optimizing the positioning of a tube coil within an ionization chamber, a handling system for transporting vial shields that maintain an operator's hand and fingers at a safe distance from a pharmaceutical vial, a method for calibrating a radiopharmaceutical delivery system in which the difference between the expected and measured activities of two radioisotopes are used to calculate an estimated error in the measured activity of a third radioisotope and a vial access system that ensures an optimal draw of fluid from a radiopharmaceutical container.
摘要翻译：设置用于流体输送系统的流体路径包括管线圈，其设计成在电离室内优化地定位药物的一个或多个体积，以最佳地测量并制备用于给予患者的药物剂量。管线圈可以通过围绕管线圈定位的芯结构保持在期望的尺寸几何形状。放射性药物管理方法和系统的新发展包括但不限于用于流体输送系统的流体路径组的配置和布局，用于从药物容器（例如小瓶）刺穿和抽取流体的布置，用于优化电离室内的管线圈的定位的布置，用于运输维护操作者的手和手指与药物瓶的安全距离的小瓶护罩的处理系统，用于校准放射性药物递送系统的方法，其中，使用两个放射性同位素的预期和测量的活动来计算第三放射性同位素和小瓶进入系统的测量活动的估计误差，其确保从放射性药物容器中最佳地吸取流体。

47. 发明申请

US20050253085A1 Radiosotope generator and method of construction thereof 有权
标题翻译：放射辐射发生器及其构造方法
公开(公告)号：US20050253085A1
公开(公告)日：2005-11-17
申请号：US10511405
申请日：2002-12-11
申请人： Peter Weisner , Terence Robert Forrest
发明人： Peter Weisner , Terence Robert Forrest
IPC分类号： G21G1/00 , A61M36/08 , G21G4/08 , G01N21/01
CPC分类号： G21G4/08
摘要： A device for producing a fluid containing a radioactive constituent, comprising a shielded chamber (5) with an opening for receiving an isotope container (6) housing a radioactive isotope (7); a chamber closure (18) adapted for cooperating with and closing the chamber opening; a first fluid port comprising a first hollow needle projecting into the shielded chamber from the chamber closure for fluid communication with the isotope container; a second fluid port comprising a second hollow needle projecting into the shielded chamber from the closed end of the chamber opposite the chamber closure for fluid communication with the isotope container; first and second compressible buffers (28, 29) mounted so as to surround at least partially the respective first and second hollow needles (12, 13), each buffer providing an outer surface for contact with opposed ends of the isotope container; and a spacer of a predetermined thickness associated with one or each of the first and second compressible buffers for determining the positioning of the isotope container within the shielded chamber.
摘要翻译：一种用于生产含有放射性成分的流体的装置，包括具有用于容纳放射性同位素（7）的同位素容器（6）的开口的屏蔽室（5）; 适于与腔室开口配合和关闭的腔室封闭件（18）; 第一流体端口，包括从腔室盖突出到屏蔽室中的第一中空针头，用于与同位素容器流体连通; 第二流体端口，其包括从室的封闭端突出到屏蔽室中的第二中空针，所述封闭端与腔室相对，用于与同位素容器流体连通; 第一和第二可压缩缓冲器（28,29）安装成至少部分地围绕相应的第一和第二中空针（12,13），每个缓冲器提供用于与同位素容器的相对端接触的外表面; 以及与第一和第二可压缩缓冲器中的一个或第二可压缩缓冲器相关联的预定厚度的间隔件，用于确定同位素容器在屏蔽室内的定位。

48. 发明授权

US5552612A Transport container for transporting radiation shield member 失效
标题翻译：用于运输辐射屏蔽构件的运输集装箱
公开(公告)号：US5552612A
公开(公告)日：1996-09-03
申请号：US362161
申请日：1994-12-22
申请人： Hitoshi Katayama , Noboru Minamiguchi , Yoshimasa Tanaka
发明人： Hitoshi Katayama , Noboru Minamiguchi , Yoshimasa Tanaka
IPC分类号： A61M5/178 , A61M36/08 , G21F5/00
CPC分类号： A61M5/1785
摘要： A transport container for transporting a radiation shield member which is light and capable of preventing a radiation shield member from popping out from the transport container by accident. The container has a favorable operability, and is capable of easily separating a reusable portion and a portion other than the reusable portion. The transport container includes a cup-shaped sheath container, a radiation shield container accommodated in the sheath container and having concaves recesses, formed thereon, engaging wing-shaped holding members of the radiation shield member, a holding frame, mounted on the sheath container, for preventing the radiation shield container and the radiation shield member from being removed from the transport container, and a cover for closing the opening end of the sheath container.
摘要翻译：一种运输容器，用于运输轻便且能够防止辐射屏蔽构件意外从运输容器中弹出的辐射屏蔽构件。容器具有良好的可操作性，并且能够容易地分离可重复使用部分和除可重复使用部分之外的部分。运输容器包括杯形护套容器，容纳在护套容器中的辐射屏蔽容器，在其上形成有凹陷部，辐射屏蔽构件的接合翼形保持构件，安装在护套容器上的保持框架，用于防止辐射屏蔽容器和辐射屏蔽构件从运输容器中移出;以及盖，用于封闭护套容器的开口端。

49. 发明授权

EP3571701B1 BIOHAZARDOUS MATERIAL TRANSPORTING PIG 有权
公开(公告)号：EP3571701B1
公开(公告)日：2022-09-14
申请号：EP17893438.6
申请日：2017-06-06
发明人： Kamen, Robert
IPC分类号： G21F5/12 , A61J1/20 , A61M36/08 , G21F5/14

50. 发明公开

EP0661074A3 Transport container for transporting radiation shield member 失效
标题翻译：用于输送辐射保护处理部的运输容器。
公开(公告)号：EP0661074A3
公开(公告)日：1997-02-26
申请号：EP94120816.7
申请日：1994-12-28
申请人： NIHON MEDI-PHYSICS Co., Ltd.
发明人： Katayama, Hitoshi, c/o Nihon Medi-Physics Co.Ltd. , Minamiguchi, Noboru, c/o Nihon Medi-Physics Co.Ltd , Tanaka, Yoshimasa, c/o Nihon Medi-Physics Co.Ltd
IPC分类号： A61M36/08
CPC分类号： A61M5/1785
摘要： A transport container transports a radiation shield member and is light and capable of preventing a radiation shield member from popping out from the transport container by accident, and has a favorable operability, and is capable of easily separating a reusable portion and a portion other than the reusable portion. The transport container (1) includes a cup-shaped sheath container (2); a radiation shield container (9) accommodated in the sheath container and having concaves (11), formed thereon, engaging wing-shaped holding members (102) of the radiation shield member (100); a holding frame (12), mounted on the sheath container, for preventing the radiation shield container and the radiation shield member from being removed from the transport container; and a cover (3) for closing the opening end of the sheath container.

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