专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明公开

EP1948314A2 TISSUE IRRADIATION WITH SHIELDING 审中-公开
标题翻译：带有辐射屏蔽面料
公开(公告)号：EP1948314A2
公开(公告)日：2008-07-30
申请号：EP06837384.4
申请日：2006-11-13
申请人： Senorx, Inc.
发明人： LUBOCK, Paul , JONES, Michael
IPC分类号： A61N5/10 , A61M36/04
CPC分类号： A61N5/1015 , A61B2017/3419 , A61N2005/1005
摘要： Devices and methods are disclosed for treatment to tissue surrounding a body cavity or other intracorporeal site, such as after removal of tissue, e.g. cancer. Such a device includes a treatment location on a distal portion of the device with one or more radiation shielding components that partially encircle a radiation source at the treatment location to control emitted radiation from the radiation source. The device minimizes radiation damage to healthy tissue surrounding the body cavity or other site while irradiating tissue not shielded by the radiation shielding components. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location to seal the passageway leading to the body cavity.

42. 发明授权

EP1239920B8 ASYMMETRIC RADIATION DOSING APPARATUS AND METHOD 有权
标题翻译：非对称辐射计量装置和方法
公开(公告)号：EP1239920B8
公开(公告)日：2006-07-19
申请号：EP00993383.9
申请日：2000-12-11
申请人： CYTYC CORPORATION
发明人： WINKLER, Rance A. , PATRICK, Timothy, J.
IPC分类号： A61N5/10
CPC分类号： A61N5/1015 , A61N2005/1005
摘要： An interstitial brachytherapy apparatus of the invention delivers radioactive emissions in an asymmetric fashion to target tissue surrounding a surgical extraction site. The apparatus includes an expandable outer surface element defining an apparatus spatial volume, a radiation source disposed within the apparatus volume, and a means for providing predetermined asymmetric isodose curves within the target tissue. In one configuration, asymmetric isodose curves are created in the target tissue by shaping or locating the radiation source so as to be asymmetrically placed with respect to a longitudinal axis of the apparatus. In other configurations, asymmetric radiopaque shielding is provided between the radiation source and the target tissue. A surgical procedure using the apparatus is also described.
摘要翻译：本发明的间质近距离放射治疗设备以不对称方式递送放射性发射以靶向手术提取部位周围的组织。该设备包括限定设备空间体积的可扩张外表面元件，设置在设备体积内的辐射源以及用于在目标组织内提供预定不对称等剂量曲线的装置。在一种配置中，通过使辐射源成形或定位以相对于装置的纵向轴线不对称地放置，在目标组织中产生不对称的等剂量曲线。在其他配置中，在辐射源和目标组织之间提供不对称的不透射线屏蔽。还描述了使用该设备的外科手术。

43. 发明授权

EP0740847B1 X-RAY SOURCE WITH FLEXIBLE PROBE 失效
标题翻译：具有柔性探头X射线源
公开(公告)号：EP0740847B1
公开(公告)日：2003-10-01
申请号：EP95908611.7
申请日：1995-01-19
申请人： PHOTOELECTRON CORPORATION
发明人： HARTE, Kenneth, J. , OETTINGER, Peter, E.
IPC分类号： H01J35/08 , H01J35/32 , A61N5/10
CPC分类号： A61N5/1001 , A61B90/11 , A61B2090/101 , A61N2005/1005 , H01J35/065 , H01J35/08 , H01J35/30 , H01J35/32 , H01J2201/342 , H05G1/06 , H05G1/10 , H05G1/32 , H05G1/34
摘要： This invention is directed to an x-ray source comprising a housing (12), a power supply (12A), an elongated tubular probe (14), a target assembly (26), and a beam steering assembly (29). The housing encloses an electron beam source (22), and has elements for generating an electron beam along a beam path. The power supply (12A) is programmable to control the voltage, current and timing of an electron beam. The elongated tubular probe (14) extends along a central axis from the housing (12) about the beam path. The target assembly (26) extends along the central axis and is adapted for coupling to end of the probe (14) distal from the housing (12). The target assembly (26) includes target element (26A) positioned along the beam path, wherein the target element (26A) is adapted to emit x-rays in a predetermined spectral range in response to incident electrons. The beam steering assembly (29) includes a deflection element (30), a feedback network (31) and a deflection controller (144). The deflection element (30) deflects the beam from a nominal axis to a selected surface region on the target element (26) in response to a deflection control signal. The feedback network (31) includes deflection sensing elements for sensing the deflection of the beam and elements for generating a feedback signal representative thereof.

44. 发明授权

EP0770258B1 X-RAY APPARATUS FOR APPLYING A PREDETERMINED FLUX TO AN INTERIOR SURFACE OF A BODY CAVITY 失效
标题翻译： X射线装置用于填充预定辐射河内表面BODY洞穴的
公开(公告)号：EP0770258B1
公开(公告)日：2001-10-24
申请号：EP95925598.5
申请日：1995-07-11
申请人： PHOTOELECTRON CORPORATION
发明人： SMITH, Donald, O. , SLISKI, Alan, P. , HARTE, Kenneth, J.
IPC分类号： G21K5/00 , G21K5/10
CPC分类号： A61N5/1001 , A61N2005/1005 , G21K5/04 , H01J35/08 , H01J35/30 , H01J35/32 , H01J2201/342 , H05G1/06 , H05G1/10 , H05G1/32 , H05G1/34
摘要： The present invention is directed to an x-ray source (10) for irradiating a surface defining a body cavity. The source comprises a housing (12), an elongated tubular probe (14), a target assembly (26), and an inflatable balloon (410). The housing (12) encloses an electron beam source (22) and includes elements (23) for generating an electron beam along a beam path. The tubular probe (14) extends along a central axis from the housing (12) about the beam path. The target assembly (26) extends along the central axis and is coupled to the probe distal end. The target assembly (26) includes a target element (26A, 26B) adapted to emit x-rays in response to electrons incident thereon. The probe tip assembly and associated control electronics include elements for positioning the target element in the beam path, and is substantially x-ray transparent. The balloon (410) affixed to the distal end is inflatable so as to be inflated to stretch the cavity to a shape, thus allowing a uniform delivery of dose of radiation to the surface defining a body cavity.

45. 发明公开

EP0836502A4 RADIATION TREATMENT OF THE VASCULAR SYSTEM 失效
标题翻译：血液血管系统相关的放射治疗
公开(公告)号：EP0836502A4
公开(公告)日：2001-04-18
申请号：EP97922288
申请日：1997-04-04
申请人： NOVOSTE CORP , UNIV EMORY
发明人： WAKSMAN RON , WELDON THOMAS D , MELOUL RAPHAEL F , HILLSTEAD RICHARD A , ROSEN JONATHAN J , BONNOITT GEORGE K , HALPERN DAVID S , LARSEN CHARLES E , CROCKER IAN R
IPC分类号： A61N5/00 , A61F2/958 , A61M25/00 , A61M29/02 , A61M36/04 , A61N5/10 , A61M29/00
CPC分类号： A61M37/0069 , A61M25/0029 , A61M25/1002 , A61M25/1006 , A61M2025/0037 , A61M2025/0039 , A61M2025/004 , A61N5/1002 , A61N5/1007 , A61N2005/1003 , A61N2005/1005 , A61N2005/1008 , A61N2005/1023
摘要： Apparatus for delivery of a treatment element (22) such as a radiation source, through a catheter (92) to a desired site in the interluminal passageways of a patient, such as the coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. One or more treatment elements (22), such as a capsule or pellet containing radioactive material, is positionable within the lumen (144) and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. Balloon membrane (256) can be used for angioplasty.

46. 发明公开

EP0972541A3 Intravascular radiation delivery device 审中-公开
标题翻译：血管内照射装置
公开(公告)号：EP0972541A3
公开(公告)日：2000-10-04
申请号：EP99202338.2
申请日：1999-07-15
申请人： EndoSonics Corporation , THE CLEVELAND CLINIC FOUNDATION
发明人： Ciezki, Jay P. , Jung, Eugene J. , Lee, Eric J. , Tuzcu, Emin M. , Savage, James D. , Weinhous, Martin S.
IPC分类号： A61N5/10
CPC分类号： A61N5/1002 , A61N2005/1005
摘要： A device and method for precisely delivering dosage of radiation from a radiation source to a treatment site of a vessel is provided herein. In one embodiment, the device includes a catheter which inserts into a vessel lumen of the body. The catheter includes an adjuster section for altering a portion of the radiation emitting radially from the radiation source so that the radiation source delivers an asymmetrical radiation profile to the vessel. The device can also include a catheter supporter which inhibits rotational deformation in the catheter between a catheter distal end and a catheter proximal end. This allows the delivery section to be precisely rotated to properly position the adjuster section within the vessel lumen.

47. 发明公开

EP0547139A4 EP0547139A4 - 失效
标题翻译： EP0547139A4 - Google专利
公开(公告)号：EP0547139A4
公开(公告)日：1994-01-26
申请号：EP91916517
申请日：1991-08-30
申请人： PHOTOELECTRON CORPORATION
发明人： NOMIKOS, PETER, M. , DINSMORE, MARK, T. , SLISKI, ALAN, P.
IPC分类号： A61N5/10 , H01J35/22 , H01J35/32 , H05G1/00 , H05G1/06 , H05G1/10 , H05G1/20 , H05G1/32 , H05G1/34
CPC分类号： A61N5/1001 , A61N2005/1005 , H01J35/32 , H05G1/06 , H05G1/10 , H05G1/32 , H05G1/34
摘要： A low-level, electron beam (16) activated source (10) of preselected or programmable duration and intensity x-rays. The source may be fully or partially implanted into, or surface-mounted onto a desired area to effect a preselected irradiated region. In medical applications, a method of treating malignant cells, such as tumors, in vivo, utilizing the apparatus described above.
摘要翻译：一个低电平的电子束（16）激活源（10）的预选或可编程持续时间和强度X射线。源可以完全或部分地植入或表面安装到期望的区域上以实现预选的照射区域。在医学应用中，利用上述装置在体内治疗恶性细胞如肿瘤的方法。

48. 发明申请

WO2014031950A1 DEVICE AND METHOD FOR IMPROVING BRACHYTHERAPY 审中-公开
标题翻译：改进BRACHYTHERAPY的装置和方法
公开(公告)号：WO2014031950A1
公开(公告)日：2014-02-27
申请号：PCT/US2013/056373
申请日：2013-08-23
申请人： HERSKOVIC, Arnold M.
发明人： HERSKOVIC, Arnold M.
IPC分类号： A61M36/06 , A61M25/01
CPC分类号： A61N5/1007 , A61N5/1001 , A61N5/1002 , A61N5/1014 , A61N5/1027 , A61N2005/1004 , A61N2005/1005 , A61N2005/1008 , A61N2005/101 , A61N2005/1018 , A61N2005/1023
摘要： This invention is a medicament delivery vehicle, the vehicle comprising tubular members adapted to removably receive the medicament and an expandable stent adapted to receive the tubular members. Also provided is a medicament delivery vehicle, the vehicle comprised of tubular members which receive the medicament wherein the medicament comprises discrete entities and each of said entities are removably positioned at predetermined regions within the members.
摘要翻译：本发明是一种药物输送载体，该载体包括适于可拆卸地容纳药物的管状构件和适于容纳管状构件的可扩张支架。还提供了一种药物输送载体，该载体包括接收该药物的管状构件，其中药物包括离散的实体，并且每个所述实体可移除地定位在构件内的预定区域处。

49. 发明申请

WO2008077073A2 ASYMMETRIC RADIATION DOSING DEVICES AND METHODS FOR BRACHYTHERAPY 审中-公开
标题翻译：非对称辐射剂量装置和用于短程治疗的方法
公开(公告)号：WO2008077073A2
公开(公告)日：2008-06-26
申请号：PCT/US2007/087993
申请日：2007-12-18
申请人： CYTYC CORPORATION , ALLAN, Donna , AMANTE, Greg , ANAV, Risa , BENSON, Maria , CROCKER, Michael , EDMUNDSON, Gregory, K. , HO, Friedrick , KOTMEL, Robert , MAGNUSON, Glenn , MARTIN, Gregory, T. , OCAMPO, Walter , PATEL, Mukund , PAYNE, Mark , SAMPSON, Russel, M. , SCHENCK, Jessica , STUBBS, James , ZILVERSMIT, Moshe
发明人： ALLAN, Donna , AMANTE, Greg , ANAV, Risa , BENSON, Maria , CROCKER, Michael , EDMUNDSON, Gregory, K. , HO, Friedrick , KOTMEL, Robert , MAGNUSON, Glenn , MARTIN, Gregory, T. , OCAMPO, Walter , PATEL, Mukund , PAYNE, Mark , SAMPSON, Russel, M. , SCHENCK, Jessica , STUBBS, James , ZILVERSMIT, Moshe
IPC分类号： A61N5/10
CPC分类号： A61N5/1015 , A61M25/1002 , A61M25/1011 , A61M2025/1013 , A61N2005/1005
摘要： A brachytherapy treatment device includes at least one tubular insertion member, an expandable member, and means for deflecting the at least one tubular insertion member. The tubular insertion member has a longitudinal axis and proximal and distal ends. The expandable member is disposed on and surrounding the distal end of the tubular insertion member. The distal end of the at least one deflected tubular insertion member within the first expandable member is offset from the longitudinal axis when deflected. The at least one deflected tubular insertion member is configured to receive a radiation source to position a radiation source offset with regard to the longitudinal axis to form an asymmetric radiation dosing profile. Additional brachytherapy treatment devices and methods for forming an asymmetric radiation dosing profile are disclosed.
摘要翻译：近距离放射治疗装置包括至少一个管状插入构件，可膨胀构件以及用于偏转所述至少一个管状插入构件的装置。管状插入构件具有纵向轴线以及近端和远端。可膨胀构件设置在并围绕管状插入构件的远端。第一可扩张构件内的至少一个偏转的管状插入构件的远端在偏转时偏离纵向轴线。所述至少一个偏转的管状插入构件被配置成接收辐射源以将辐射源相对于纵向轴线偏移定位以形成不对称的辐射剂量轮廓。公开了额外的近距离放射治疗装置和用于形成不对称放射剂量配置文件的方法。

50. 发明申请

WO2007053823A3 BRACHYTHERAPY APPARATUS AND METHODS OF USING SAME 审中-公开
标题翻译： BRACHYTHERAPY APPARATUS及其使用方法
公开(公告)号：WO2007053823A3
公开(公告)日：2007-08-09
申请号：PCT/US2006060368
申请日：2006-10-30
申请人： BIOLUCENT INC , HERMANN GEORGE D , SUTTON DOUG S , LEBOVIC GAIL S , CHI SING EDUARDO , BOWES ROBERT R
发明人： HERMANN GEORGE D , SUTTON DOUG S , LEBOVIC GAIL S , CHI SING EDUARDO , BOWES ROBERT R
IPC分类号： A61M36/04 , A61N5/10
CPC分类号： A61N5/1007 , A61N5/1014 , A61N5/1027 , A61N2005/1005 , A61N2005/1011 , A61N2005/1012 , A61N2005/1023 , A61N2005/1094
摘要： Apparatus, systems and methods for delivering brachytherapy to a target tissue region of a human or other mammalian body. In some embodiments, a flexible brachytherapy device is implanted that includes a therapy delivery portion having one or more radioactive sources securely retained thereto, and a tail portion extending from the therapy delivery portion. Once implanted, the tail portion may extend outside the body, where it may be folded and secured flat against the skin. The device may be removed at therapy completion. Other embodiments of the invention are directed to systems and methods for delivering brachytherapy devices to the body.
摘要翻译：用于将近距离放射治疗递送至人体或其他哺乳动物体的目标组织区域的装置，系统和方法。在一些实施例中，植入柔性近距离放射治疗装置，其包括具有安全地保持在其上的一个或多个放射源的治疗传递部分和从治疗传递部分延伸的尾部。一旦植入，尾部可以延伸到身体外部，在那里它可以被折叠并紧贴皮肤平坦地固定。治疗完成后可能会取出设备。本发明的其他实施例涉及用于将近距离放射治疗装置输送到身体的系统和方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式