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    • 44. 发明授权
    • Method for automatic dosing of drugs
    • 药物自动给药方法
    • US6056734A
    • 2000-05-02
    • US97950
    • 1998-06-16
    • Stephen C. JacobsenGaylen M. Zentner
    • Stephen C. JacobsenGaylen M. Zentner
    • A61D7/00A61M31/00A61K9/22
    • A61D7/00A61M31/002
    • The method for automatic dosing of drugs utilizes a microdelivery device which may be implanted in or otherwise administered to an animal or human. A microdelivery device is configured to have at least one compartment containing at least one drug so that a plurality of doses of the drug(s) are held within the device. In accordance with the present invention, the microdelivery device selectively actuates a compartment to selectively release doses of the drug(s) to provide an efficacious dosing pattern. One primary function of the present invention is to release two or more pesticides in such a pattern that parasites are effectively controlled while preventing the development of tolerance to the drugs within the parasites. Preferably, the microdelivery device is programmable to effectuate the release of the drug(s) at a desired time to maintain efficacious levels of the drug while minimizing the amount of drug which must be used.
    • 用于药物自动给药的方法使用可以植入或以其它方式施用于动物或人的微量输送装置。 微量输送装置被配置为具有至少一个包含至少一种药物的隔室,使得多个剂量的药物保持在该装置内。 根据本发明,微量输送装置选择性地致动隔室以选择性释放药物的剂量以提供有效的给药模式。 本发明的一个主要功能是以这样的模式释放两种或更多种杀虫剂,即在有效地控制寄生虫的同时防止对寄生虫内的药物的耐受性的发展。 优选地,微量输送装置是可编程的,以在期望的时间实现药物的释放,以保持药物的有效水平,同时最小化必须使用的药物的量。