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41. 发明申请

US20100217180A1 SIMULATION OF PATIENT DRAIN PHASE IN PERITONEAL DIALYSIS 有权
标题翻译：腹膜透析患者浸液相的模拟
公开(公告)号：US20100217180A1
公开(公告)日：2010-08-26
申请号：US12389886
申请日：2009-02-20
申请人： Alp Akonur , Ying-Cheng Lo
发明人： Alp Akonur , Ying-Cheng Lo
IPC分类号： A61M1/28 , G06F17/10 , G06G7/57 , G06G7/60
CPC分类号： G16H50/50 , A61M1/28 , A61M1/282
摘要： A method of modeling a patient's peritoneal dialysis drain phase includes (i) modeling a first segment of a drain phase curve as having a constant flowrate; (ii) modeling a second segment of a drain phase curve as having a decaying exponential flowrate; and (iii) incorporating a switching component into the first and second components so that (a) at a first time the first segment is active and while the second segment is inactive and (b) at a second time the first segment is inactive and while the second segment is active.
摘要翻译：建模患者腹膜透析排泄阶段的方法包括（i）将排水相曲线的第一段建模为具有恒定的流速; （ii）将排水相曲线的第二段建模为具有衰减指数流速; 以及（iii）将切换组件并入到所述第一和第二组件中，使得（a）在第一时间第一段处于活动状态，而第二段处于非活动状态，并且（b）在第二时间段，第一段无效，而第二段是活跃的。

42. 发明申请

US20100217179A1 BULK DELIVERY PERITONEAL DIALYSIS SYSTEM AND METHOD 审中-公开
标题翻译：大容量输送透析系统和方法
公开(公告)号：US20100217179A1
公开(公告)日：2010-08-26
申请号：US12390002
申请日：2009-02-20
申请人： Ying-Cheng Lo , Rohit Vishnoi
发明人： Ying-Cheng Lo , Rohit Vishnoi
IPC分类号： A61M1/28
CPC分类号： A61M1/28 , A61M1/285 , A61M1/288
摘要： A peritoneal dialysis method includes (i) connecting smaller and larger supply containers to a junction, the smaller and larger supply bags both full of dialysate; (ii) allowing the junction to be connected to a patient's transfer set; allowing the patient to drain through the junction; (iii) allowing the patient to fill from the smaller supply container; and (iv) allowing the patient to refill the smaller supply container from the larger supply container.
摘要翻译：腹膜透析方法包括（i）将较小和较大的供应容器连接到交界处，较小和较大的充满透析液的供应袋; （ii）允许接头连接到患者的转移组件; 允许患者通过交界处排出; （iii）允许患者从较小的供应容器中填充; 和（iv）允许患者将更小的供应容器从较大的供应容器中重新填充。

43. 发明申请

US20100198138A1 TRANSFER SETS FOR THERAPY OPTIMIZATION 有权
标题翻译：转移治疗方案优化
公开(公告)号：US20100198138A1
公开(公告)日：2010-08-05
申请号：US12696889
申请日：2010-01-29
申请人： Paul R. Chapman , Brian J. Connell , Ying-Cheng Lo
发明人： Paul R. Chapman , Brian J. Connell , Ying-Cheng Lo
IPC分类号： A61M39/28 , A61M1/28
CPC分类号： A61M1/285 , A61M39/12 , A61M39/28 , A61M39/286
摘要： Transfer sets are disclosed in the present patent. The transfer set provides a connection between a source of peritoneal dialysis fluid and a patient for whom peritoneal dialysis has been prescribed. The transfer sets disclosed herein are smaller and provide a more compact and convenient device by which a dialysis patient controls the flow of dialysis fluid to and from the peritoneum of the patient. The devices are more compact and convenient because they include more convenient mechanisms for starting and stopping flow of the dialysis fluid. It is also easy to determine whether the mechanism is in a closed or open configuration by simply looking at the mechanism.
摘要翻译：转让集合在本专利中公开。转移组提供腹膜透析液源和已经规定了腹膜透析的患者之间的连接。本文公开的转移组较小，并且提供更紧凑和方便的装置，通过该装置透析患者控制透过液流入和离开患者腹膜的流动。这些装置更紧凑和便利，因为它们包括更方便的起始和停止透析液流动的机构。通过简单地查看机制，也很容易确定机制是否处于关闭或打开配置。

44. 发明申请

US20100191181A1 DRAIN AND FILL LOGIC FOR AUTOMATED PERITONEAL DIALYSIS 有权
标题翻译：用于自动化透析的排水和填充逻辑
公开(公告)号：US20100191181A1
公开(公告)日：2010-07-29
申请号：US12362259
申请日：2009-01-29
申请人： Robert W. Childers , Peter A. Hopping , Ying-Cheng Lo
发明人： Robert W. Childers , Peter A. Hopping , Ying-Cheng Lo
IPC分类号： A61M1/28
CPC分类号： A61M1/284 , A61M1/28 , A61M1/281 , A61M1/282 , A61M2205/3379 , B01D61/30 , B01D61/32
摘要： A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments short the next fill, if necessary, to limit the intra-peritoneal volume, add a cycle, if necessary, to use all of the available dialysis solution and will average the remaining dwell time to maximize the therapeutic benefit of the therapy in the allotted time. In another embodiment, a tidal therapy using trended patient UF data is provided.
摘要翻译：一种用于自动调节连续循环腹膜透析（“CCPD”）治疗的系统和方法，以最大限度地减少腹膜内多余的体积。调整是在排水结束时进行的，就在下一次填充之前。如果需要，调整缩短下一次填充，以限制腹膜内体积，如果需要，添加一个循环，以使用所有可用的透析溶液，并将平均剩余停留时间，以最大化治疗的治疗效果分配时间在另一个实施例中，提供使用趋势化患者UF数据的潮汐治疗。

45. 发明申请

US20100130920A1 DIALYSIS MACHINE HAVING AUTO-CONNECTION SYSTEM WITH ROLLER OCCLUDER 有权
标题翻译：具有滚筒式自动连接系统的DIALYSIS MACHINE
公开(公告)号：US20100130920A1
公开(公告)日：2010-05-27
申请号：US12275982
申请日：2008-11-21
申请人： Ying-Cheng Lo , Yuanpang Samuel Ding
发明人： Ying-Cheng Lo , Yuanpang Samuel Ding
IPC分类号： A61M1/28 , B01D61/32
CPC分类号： A61M1/28 , A61M39/20 , A61M2205/10 , A61M2205/12 , A61M2205/121 , A61M2205/505 , A61M2205/7536
摘要： A medical fluid or dialysis system includes an auto-connection mechanism that connects connectors from the supply bags to dialysis cassette ports or cassette supply lines. The system provides for multiple, e.g., four, supply bags, which can be connected to a manifold of the auto-connection mechanism. Tip protecting caps that protect the supply line ends and cassette ports or cassette supply line ends are made to be compatible with the auto-connection mechanism. The auto-connection mechanism removes all the caps and connects the supply lines to the cassette. At least one roller occluder is provided that occludes the supply tubing prior to the tip protecting caps being removed. The roller occludes prevent medical dialysis fluid from spilling out of the supply lines between the time that the caps are removed and connection to the cassette is made.
摘要翻译：医疗液体或透析系统包括将供应袋的连接器连接到透析盒端口或盒式电源线的自动连接机构。该系统提供多个例如四个供应袋，其可以连接到自动连接机构的歧管。保护电源线端头和磁带盒端口或磁带盒供电线端头的保护帽与自动连接机构兼容。自动连接机构移除所有盖子并将供应线连接到盒式磁带。提供至少一个辊封闭器，其在尖端保护盖被移除之前封闭供应管。滚筒阻塞防止医用透析液从盖子被移除的时间和连接到盒子之间溢出供应管线。

46. 发明申请

US20090275883A1 SMART PATIENT TRANSFER SET FOR PERITONEAL DIALYSIS 有权
标题翻译：智能患者转移器用于腹膜透析
公开(公告)号：US20090275883A1
公开(公告)日：2009-11-05
申请号：US12431479
申请日：2009-04-28
申请人： Paul Chapman , Brian Connell , Ying-Cheng Lo
发明人： Paul Chapman , Brian Connell , Ying-Cheng Lo
IPC分类号： A61M1/28 , G08B1/08
CPC分类号： G06F19/3406 , A61M1/28 , A61M1/282 , A61M2205/3569 , A61M2205/6054 , A61M2205/6072 , G06F19/00 , G06F19/3481 , G16H40/63
摘要： A peritoneal dialysis system includes: a dialysis fluid container associated with an identifier; a reader for reading the identifier; a signal transmitter for communicating data based on the identifier; and a patient transfer set for semi-permanent connection to a patient, the patient transfer set including: (i) a signal receiver for receiving the data sent by the signal transmitter, (ii) an output device for communicating with the patient, and (iii) electronics configured to received the data and command the output device to communicate with the patient accordingly.
摘要翻译：腹膜透析系统包括：与标识符相关联的透析液容器; 用于读取标识符的读取器; 信号发送器，用于基于所述标识符传送数据; 以及用于与患者半永久连接的患者转移组，所述患者转移组包括：（i）用于接收由所述信号发送器发送的数据的信号接收器，（ii）用于与患者通信的输出装置，和 iii）被配置为接收数据并命令输出设备相应地与患者通信的电子设备。

47. 发明申请

US20090275881A1 OPTIMIZING THERAPY OUTCOMES FOR PERITONEAL DIALYSIS 有权
标题翻译：优化治疗结果进行透析
公开(公告)号：US20090275881A1
公开(公告)日：2009-11-05
申请号：US12431458
申请日：2009-04-28
申请人： Ying-Cheng Lo , Alp Akonur , Isaac Martis
发明人： Ying-Cheng Lo , Alp Akonur , Isaac Martis
IPC分类号： A61M1/28 , A61B5/00 , A61B5/107 , G06F17/10 , G06F17/30
CPC分类号： G06F19/3481 , A61M1/28 , A61M1/281 , A61M1/282 , A61M2205/3569 , A61M2205/52 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , G06F19/00
摘要： Peritoneal dialysis therapy outcomes have been calculated for a variety of dwell times of peritoneal dialysis fluids in the peritoneal cavities of dialysis patients using kinetic modeling. The length of dwell time should not be the same for every patient, but should vary according to the patient condition and needs. Some patients have a potential for expressing greater ultrafiltrate into the dialysis fluid, and these patients can benefit from a longer dwell time, whereas other patients with less potential will not benefit from a longer dwell time. An optimal or peak time is observed for each peritoneal dialysis therapy outcome, such as ultrafiltrate volume rate, urea clearance (Kt/V), and creatinine clearance, while minimizing hydrocarbon absorption. These values and input parameters can be used to tailor the peritoneal dialysis dwell time for each patient, estimating the peak dwell time that will yield the best therapy outcome for each patient.
摘要翻译：已经使用动力学模型计算了透析患者腹膜腔腹膜透析液的各种停留时间的腹膜透析治疗结果。每个患者的停留时间长度不应相同，但应根据患者情况和需要而变化。一些患者有可能在透析液中表达更多的超滤液，这些患者可以从更长的停留时间中受益，而潜在的潜力较小的患者不会受益于更长的停留时间。对于每个腹膜透析治疗结果观察到最佳或高峰时间，例如超滤液体积率，尿素清除率（Kt / V）和肌酐清除率，同时使烃吸收最小化。这些值和输入参数可用于定制每个患者的腹膜透析停留时间，估计将为每位患者产生最佳治疗结果的峰值停留时间。

48. 发明申请

US20070278155A1 Medical fluid system with flexible sheeting disposable unit 有权
标题翻译：医用液体系统，柔性片材一次性装置
公开(公告)号：US20070278155A1
公开(公告)日：2007-12-06
申请号：US11530842
申请日：2006-09-11
申请人： Ying-Cheng Lo , Robert W. Childers , Thomas D. Kelly , Justin Rohde
发明人： Ying-Cheng Lo , Robert W. Childers , Thomas D. Kelly , Justin Rohde
IPC分类号： A61M37/00
CPC分类号： A61M1/1639 , A61M1/16 , A61M1/1603 , A61M1/1605 , A61M1/1635 , A61M1/166 , A61M1/28 , A61M1/284 , A61M1/34 , A61M1/3627 , A61M2205/127 , A61M2205/3331 , A61M2205/3368 , A61M2205/502 , Y10T29/49826
摘要： A kidney failure therapy system includes: (a) a dilaysate supply; (b) at least one valve actuator; (c) at least one pump actuator; and (d) a disposable unit including first and second flexible sheets sealed together for form: (i) at least one flow path configured to be placed in fluid communication with the dilaysate supply; and operable with the at least one valve actuator; and (ii) at least one pumping portion configured to operate with the at least one pump actuator.
摘要翻译：肾衰竭治疗系统包括：（a）稀释供应; （b）至少一个阀致动器; （c）至少一个泵致动器; 和（d）包括密封在一起的第一和第二柔性片的一次性单元，用于形成：（i）至少一个流路，被配置为与所述稀释片供应流体连通; 并且可与所述至少一个阀致动器一起操作; 和（ii）配置成与所述至少一个泵致动器一起操作的至少一个泵送部分。

49. 发明授权

US06344020B1 Bearing and umbilicus gimbal with bearing retainer in blood processing system 失效
标题翻译：轴承和脐带万向架与血液处理系统中的轴承保持架
公开(公告)号：US06344020B1
公开(公告)日：2002-02-05
申请号：US09455203
申请日：1999-12-06
申请人： Douglas Reitz , Ying-Cheng Lo , John Joseph Belle , Richard West , Timothy Patno
发明人： Douglas Reitz , Ying-Cheng Lo , John Joseph Belle , Richard West , Timothy Patno
IPC分类号： B04B700
CPC分类号： F16C33/44 , B04B5/0442 , B04B2005/045 , B04B2005/0492 , F16C23/084 , F16C33/41
摘要： A bearing supports a rotating element. The bearing comprises an inner annular body and an outer annular body about the inner annular body. A bearing surface, which is located between the inner annular body and the outer annular body, supports the outer annular body for rotation about the inner annular body. A cage supports the bearing surface during rotation of the outer annular body about the inner annular body. The cage includes a material that imparts increased flexural modulus that resists deformation during rotation.
摘要翻译：轴承支撑旋转元件。轴承包括内环形体和围绕内环形体的外环形体。位于内部环形体和外部环形体之间的支承表面支撑外部环形体以围绕内部环形体旋转。在外环形体围绕内环形体旋转期间，保持架支撑轴承表面。笼子包括赋予旋转时抵抗变形的增加的弯曲模量的材料。

50. 发明授权

US5948385A Antimicrobial materials 失效
标题翻译：抗菌材料
公开(公告)号：US5948385A
公开(公告)日：1999-09-07
申请号：US940579
申请日：1997-09-30
申请人： John R. Chapman , Ying-Cheng Lo , Winnie Kubey , Clifford J. Holmes , David Bell
发明人： John R. Chapman , Ying-Cheng Lo , Winnie Kubey , Clifford J. Holmes , David Bell
IPC分类号： A01N59/12 , A61K47/48 , A61L15/46 , A61L17/00 , A61L31/16 , A61K51/00
CPC分类号： A61L31/16 , A01N59/12 , A61K47/48176 , A61K47/48192 , A61K47/482 , A61L15/46 , A61L17/005 , A61L2300/202 , A61L2300/404 , A61L2300/602
摘要： An antimicrobial material incorporated with a molecular halogen is provided. The antimicrobial material includes a plastic material and a molecular halogen entrapped within the plastic material. A directional release material is also provided in the present application. The directional release material allows for the control of the rate and site of halogen release. Still further, method of impregnating a plastic material are also provided.
摘要翻译：提供了掺有分子卤素的抗微生物材料。抗微生物材料包括塑料材料和被包埋在塑料材料内的分子卤素。在本申请中还提供定向释放材料。定向释放材料允许控制卤素释放的速率和位置。此外，还提供了浸渍塑料材料的方法。

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