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41. 发明授权

US4939462A Method and apparatus for MRI 失效
标题翻译： MRI的方法和装置
公开(公告)号：US4939462A
公开(公告)日：1990-07-03
申请号：US376216
申请日：1989-07-03
申请人： Akira Maeda , Koichi Sano , Tetsuo Yokoyama , Hideaki Koizumi
发明人： Akira Maeda , Koichi Sano , Tetsuo Yokoyama , Hideaki Koizumi
IPC分类号： A61B5/055 , G01R33/48 , G01R33/54
CPC分类号： G01R33/4833
摘要： In order to narrow the dynamic range of an NMR signal and to provide MRI of low cost and high image quality without inducing the distortions of an image other than distortion of phase which can be corrected or the degradations of the measurement accuracies of various parameters, a coil for generating an inhomogeneous magnetic field which varies slowly within region to-be-imaged is added to a coil for generating a static magnetic field of high homogeneity, and current to flow through the former coil is changed so as to control the inhomogeneous magnetic field.

42. 发明授权

US4724388A Magnetic resonance imaging method 失效
标题翻译：磁共振成像方法
公开(公告)号：US4724388A
公开(公告)日：1988-02-09
申请号：US869976
申请日：1986-06-02
申请人： Koichi Sano , Tetsuo Yokoyama , Hideaki Koizumi
发明人： Koichi Sano , Tetsuo Yokoyama , Hideaki Koizumi
IPC分类号： G01R33/565 , G01R33/20
CPC分类号： G01R33/56518 , G01R33/56563
摘要： In order to measure a static field distribution with one scanning operation and to make image distortion corrections with the static field distribution and a gradient field distribution simultaneously considered, an image is reconstructed using a spin echo signal produced under the condition that a time interval between a 90.degree. pulse and a 180.degree. pulse differs from an interval between the 180.degree. pulse and the time origin of the spin echo signal, the static field distribution is evaluated from the relation of distortions to phase errors free from a phase distortion attributed to the characteristic of a detecting part and a phase distortion attributed to the dynamic characteristic of the gradient field, a relations existing between the spatial distortion and phase distortion of the reconstructed image and a magnetic field distribution including the gradient field is obtained, and the distortion magnitude of the reconstructed image is evaluated from the measured magnetic field distribution.
摘要翻译：为了通过一次扫描操作测量静态场分布，并且同时考虑静态场分布和梯度场分布进行图像失真校正，使用自旋回波信号来重构图像，该自旋回波信号是在 90°脉冲和180°脉冲与180°脉冲与自旋回波信号的时间原点之间的间隔不同，静态场分布从失真和相位误差的关系来评估，该相位误差不包括归因于特性的相位失真得到归因于梯度场的动态特性的检测部分和相位失真，获得重建图像的空间失真和相位失真之间存在的关系以及包括梯度场的磁场分布，并且，从测量的磁场分布评估重建图像。

43. 发明授权

US4504145A Apparatus capable of measurement of profile of emission line spectrum 失效
标题翻译：能够测量发射线光谱曲线的装置
公开(公告)号：US4504145A
公开(公告)日：1985-03-12
申请号：US411370
申请日：1982-08-25
申请人： Hideaki Koizumi
发明人： Hideaki Koizumi
IPC分类号： G01N21/31 , G01J3/00 , G01J3/443
CPC分类号： G01J3/443
摘要： Light from a light source emitting a line spectrum is passed through an absorbing cell. A metal element is enclosed in the absorbing cell, and the temperature of the absorbing cell is controlled to maintain a predetermined atomic vapor pressure of the metal element. This absorbing cell is disposed in the gap between the poles of an electromagnet. A linear polarizer is disposed between the light source and the absorbing cell. Light passed through the absorbing cell is led via a spectroscope toward a light sensor. While the light is being directed from the light source toward the absorbing cell, the value of current supplied to the electromagnet is changed to vary the intensity of the magnetic field. With the field intensity variation, the wavelength of a component split from the absorption line of the atomic vapor in the absorbing cell is shifted. This wavelength-shifted component is scanned along the wavelength of the line spectrum emitted from the light source, whereby the profile of the emission line spectrum can be measured.
摘要翻译：来自发射线谱的光源的光通过吸收单元。将金属元件封装在吸收单元中，并且控制吸收单元的温度以保持金属元件的预定的原子蒸气压。该吸收单元设置在电磁体的极之间的间隙中。线性偏振器设置在光源和吸收单元之间。通过吸收单元的光通过分光镜被引导到光传感器。当光从光源引向吸收单元时，改变提供给电磁体的电流值以改变磁场的强度。随着场强变化，从吸收单元中的原子蒸气的吸收线分离的分量的波长发生偏移。沿着从光源发射的线谱的波长扫描该波长偏移分量，由此可以测量发射谱谱的轮廓。

44. 发明申请

US20150192604A1 HOLDER FOR PROBE MICROSCOPE, PROBE MICROSCOPE AND SPECIMEN MEASUREMENT METHOD 审中-公开
标题翻译：探针显微镜，探针显微镜和样本测量方法
公开(公告)号：US20150192604A1
公开(公告)日：2015-07-09
申请号：US14417407
申请日：2012-07-27
申请人： Tsuyoshi Yamamoto , Seiji Heike , Akira Nambu , Tomihiro Hashizume , Hideaki Koizumi
发明人： Tsuyoshi Yamamoto , Seiji Heike , Akira Nambu , Tomihiro Hashizume , Hideaki Koizumi
IPC分类号： G01Q30/20 , G01Q60/24
CPC分类号： G01Q30/20 , G01Q30/02 , G01Q30/10 , G01Q30/14 , G01Q60/24
摘要： At the time of carrying out measurement of a biological tissue with a probe microscope, measurement is to be realized while maintain survival conditions for a cell.As a holder for the probe microscope, a measurement holder including: a container in which a measurement object is housed; a first cover section which covers at least a part of the measurement object and has an aperture for inserting a measurement probe; and a second cover section which is connected to the first cover section, covers the container, and has an aperture for inserting the measurement probe, is used.
摘要翻译：在用探针显微镜进行生物体组织的测定时，要保持细胞的生存条件，进行测定。作为探针显微镜的保持器，测量保持器包括：容纳测量对象的容器; 第一覆盖部分，其覆盖所述测量对象的至少一部分并且具有用于插入测量探针的孔; 并且连接到第一盖部分的第二盖部分覆盖容器，并且具有用于插入测量探针的孔。

45. 发明授权

US06478738B1 Method of mass-analyzing body fluid and apparatus therefor 有权
标题翻译：体液质量分析方法及其设备
公开(公告)号：US06478738B1
公开(公告)日：2002-11-12
申请号：US09695019
申请日：2000-10-25
申请人： Yukiko Hirabayashi , Atsumu Hirabayashi , Hideaki Koizumi
发明人： Yukiko Hirabayashi , Atsumu Hirabayashi , Hideaki Koizumi
IPC分类号： A61B500
CPC分类号： H01J49/0431 , A61B5/145 , A61B5/14528 , A61B5/14557 , A61B5/1459 , A61B5/4064 , A61B2010/0077
摘要： A living body fluid mass-analyzing method introducing a first solution whose osmotic pressure is close to that of a living body fluid into a microdialysis, extracting the living body fluid from the microdialysis, mixing the living body fluid from the microdialysis and an organic solution, and applying a gas around a capillary through which the mixed living fluid flows thereby spraying and ionizing the living body fluid by the gas. Further, the ionized ions are introduced into three dimensional mass-analyzer through an orifice, accumulating the ions in said three dimensional mass-analyzer and sending out the accumulated ions in order of mass to measure mass numbers of the ions.
摘要翻译：一种生物体液分析方法，其将渗透压接近生物体液的第一溶液引入微透析，从微透析提取生物体液，混合来自微透析的活体液和有机溶液，并且在毛细管周围施加气体，混合的生物流体通过该毛细管喷射并通过气体电离生物体液。此外，通过孔口将离子化离子引入三维质量分析器中，将离子积聚在所述三维质量分析器中，并以质量的顺序排出积聚的离子以测量离子的质量数。

46. 发明授权

US06437327B2 Mass spectrometry of solution and apparatus therefor 有权
标题翻译：溶液质谱仪及其设备
公开(公告)号：US06437327B2
公开(公告)日：2002-08-20
申请号：US09859508
申请日：2001-05-18
申请人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
发明人： Yasuaki Takada , Minoru Sakairi , Atsumu Hirabayashi , Takayuki Nabeshima , Hideaki Koizumi
IPC分类号： H01J4910
CPC分类号： H01J49/165 , G01N30/7266 , H01J49/168
摘要： A mass spectrometer including a sprayer for spraying a sample solution, a needle electrode for ionizing the sample contained in the sample solution, an aperture for introducing the ions of the sample into a lower pressure region having a pressure lower than the pressure of a region in which the needle electrode is disposed, and a mass spectrometric apparatus for analyzing the ions introduced from the aperture. A direction of a spray caused by the sprayer is almost perpendicular to or at an angle with respect to a center axis of the aperture, and a tip of the needle is disposed facing to an electrode having the aperture.
摘要翻译：一种质谱仪，包括用于喷射样品溶液的喷雾器，用于使包含在样品溶液中的样品电离的针状电极，用于将样品的离子引入低于区域压力的低压区域的孔设置针状电极的质谱仪和用于分析从孔径引入的离子的质谱仪。由喷雾器引起的喷雾方向几乎与孔的中心轴垂直或成一定角度，并且针的尖端面向具有孔的电极。

47. 发明授权

US6114693A Mass spectrometer and mass spectrometry method for analyzing compounds contained in a solution 有权
标题翻译：用于分析溶液中所含化合物的质谱仪和质谱法
公开(公告)号：US6114693A
公开(公告)日：2000-09-05
申请号：US299638
申请日：1999-04-27
申请人： Atsumu Hirabayashi , Yukiko Hirabayashi , Minoru Sakairi , Yasuaki Takada , Takayuki Nabeshima , Hideaki Koizumi
发明人： Atsumu Hirabayashi , Yukiko Hirabayashi , Minoru Sakairi , Yasuaki Takada , Takayuki Nabeshima , Hideaki Koizumi
IPC分类号： G01N27/62 , G01N27/447 , G01N30/72 , H01J49/04 , H01J49/10
CPC分类号： G01N30/7266 , H01J49/0468 , H01J49/167
摘要： A mass spectrometer comprising a passage through which a sample solution flows, the passage including a capillary having an open tip, the sample solution flowing through the capillary out of the open tip of the capillary, a gas passage which forms a gas flow around the open tip of the capillary, the gas flow spraying the sample solution flowing out of the open tip of the capillary, a first electrode which contacts the sample solution flowing in the passage and applies an electric potential to the sample solution flowing in the passage, a second electrode disposed around the capillary near the open tip of the capillary, the second electrode being downstream from the first electrode with respect to a direction in which the sample solution flows in the passage, there being no gap extending downstream from the open tip of the capillary to the second electrode in a direction in which the sample solution flows out of the open tip of the capillary, the second electrode being electrically isolated from the sample solution flowing in the capillary and applying an electric field to the sample solution flowing in the capillary, and an analyzer which analyzes a mass of gaseous ions formed from the sample solution sprayed by the gas flow.
摘要翻译：一种质谱仪，包括样品溶液流过的通道，所述通道包括具有开口尖端的毛细管，所述样品溶液从毛细管的开口尖端流过毛细管，气体通道围绕开口形成气流毛细管的尖端，气流喷射从毛细管的开口尖端流出的样品溶液，第一电极，其接触在通道中流动的样品溶液，并向在通道中流动的样品溶液施加电位，第二电极设置在毛细管附近的毛细管周围的电极，第二电极相对于样品溶液在通道中流动的方向从第一电极下游，在毛细管的开口尖端的下游没有间隙在样品溶液从毛细管的开口尖端流出的方向到第二电极，第二电极是电隔离的从在毛细管中流动的样品溶液流出并向在毛细管中流动的样品溶液施加电场，以及分析器，其分析由气流喷射的样品溶液形成的气态离子的质量。

48. 发明授权

US6075243A Mass spectrometer 失效
标题翻译：质谱仪
公开(公告)号：US6075243A
公开(公告)日：2000-06-13
申请号：US827184
申请日：1997-03-27
申请人： Takayuki Nabeshima , Minoru Sakairi , Yasuaki Takada , Yukiko Hirabayashi , Hideaki Koizumi
发明人： Takayuki Nabeshima , Minoru Sakairi , Yasuaki Takada , Yukiko Hirabayashi , Hideaki Koizumi
IPC分类号： G01N27/62 , G01N30/72 , H01J49/02 , H01J49/26 , H01J49/42 , B01D59/44 , H01J49/00
CPC分类号： H01J49/424 , H01J49/044 , H01J49/4255
摘要： A mass spectrometer in which, in order to reduce noise due to other particles (large charge droplets, neutral particles, photons, or the like), the orbit of ions and the orbit of other particles are separated from each other in the inside of a mass analysis region so as to make it possible to prevent the other particles from reaching an ion detection region without using any deflector.
摘要翻译：一种质谱仪，其中为了减少由于其它颗粒（大电荷液滴，中性粒子，光子等）引起的噪声，离子的轨道和其它颗粒的轨道在一个质量分析区域，使得可以防止其他颗粒在不使用任何偏转器的情况下到达离子检测区域。

49. 发明授权

US5839953A Air-direction adjusting apparatus for air-conditioning equipment 失效
公开(公告)号：US5839953A
公开(公告)日：1998-11-24
申请号：US853181
申请日：1997-05-07
申请人： Satoru Kotoh , Kiyoshi Sakuma , Takayuki Yoshida , Hiromi Sano , Katuyuki Aoki , Shin'ichi Suzuki , Hideaki Koizumi , Kaoru Yamamoto , Kunio Matsushita , Kenichi Unno , Tomoko Oguma
发明人： Satoru Kotoh , Kiyoshi Sakuma , Takayuki Yoshida , Hiromi Sano , Katuyuki Aoki , Shin'ichi Suzuki , Hideaki Koizumi , Kaoru Yamamoto , Kunio Matsushita , Kenichi Unno , Tomoko Oguma
IPC分类号： F16K1/16 , F24F1/00 , F24F13/075 , F24F13/15
CPC分类号： F24F13/075 , F16K1/165 , F24F1/00
摘要： A mechanism for controlling the flow of air from an air-conditioning unit includes a row of guide vanes which are pivotally held by an outlet nozzle. The guide vanes are located at the lower end of an air course which has been formed within a body of the air-conditioning unit. The guide vanes control the flow of air in both left and right directions. This new design is characterized in that the angle of inclination of each guide vane progressively changes toward the end of the row. The air flow is controlled accurately in both the left and right directions so that the air flow reaches the desired location.

50. 发明授权

US5251629A Inspection method and apparatus utilizing nuclear magnetic resonance 失效
标题翻译：利用核磁共振的检测方法和装置
公开(公告)号：US5251629A
公开(公告)日：1993-10-12
申请号：US915400
申请日：1992-07-20
申请人： Hideaki Koizumi , Kazuya Sukegawa
发明人： Hideaki Koizumi , Kazuya Sukegawa
IPC分类号： A61B5/055 , G01R33/567
CPC分类号： G01R33/56509 , A61B5/0555
摘要： A method of and an apparatus for inspecting a physical portion having physiological movement, for example, the abdominal region moving with breathing, by utilizing nuclear magnetic resonance. The circumstances of that area of the surface of the abdominal region which exists on a plane indicative of a slice to be imaged, is made different from the circumstances of the surface of the remaining physical portion. In this case, a person to be inspected feels a foreign matter at the abdominal region, and suppresses the movement of the abdominal region due to breathing, consciously and unconsciously, thereby moving the breast with breathing. Thus, the to-be-inspected abdominal region is kept quiet, and an accurate inspection can be made in a short period of time.
摘要翻译：通过利用核磁共振来检查具有生理运动的物理部分的方法和装置，例如通过呼吸移动的腹部区域。存在于指示要成像的切片的平面上的腹部区域的表面的区域的情况与剩余物理部分的表面的情况不同。在这种情况下，被检查者在腹部感觉到异物，有意识地和无意识地抑制由呼吸引起的腹部运动，从而使呼吸的乳房移动。因此，被检查的腹部区域保持安静，并且可以在短时间内进行准确的检查。

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