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41. 发明授权

US06234290B1 Actuating installation for pneumatic clutch actuation with overload protection and/or incorrect-operation protection 失效
标题翻译：具有过载保护和/或不正确操作保护的气动离合器驱动的执行安装
公开(公告)号：US06234290B1
公开(公告)日：2001-05-22
申请号：US09369825
申请日：1999-08-06
申请人： Hans-Jürgen Drexl , Barbara Ester , Frank Hirschmann , Jürgen Liebler , Joachim Lindner , Thomas Otto , Jörg Pankoke , Winfried Stürmer
发明人： Hans-Jürgen Drexl , Barbara Ester , Frank Hirschmann , Jürgen Liebler , Joachim Lindner , Thomas Otto , Jörg Pankoke , Winfried Stürmer
IPC分类号： F16D2508
CPC分类号： F16D25/083 , B60K23/02 , B60T7/06 , F16D25/14 , F16D48/02 , F16D2048/0203 , F16D2048/0212 , F16D2048/0215 , F16D2048/0221
摘要： An actuating installation for a friction clutch arranged in the drive line between a drive unit and a transmission. The installation having an actuating arrangement for the actuation of the friction clutch and a clutch-pedal arrangement, which is connected to the actuating arrangement and has a clutch pedal, which, in a first operating state, is actuable according to a force-travel characteristic of a first type. The actuating installation has a signaling and/or protection device, which is in operative connection with or is operatively integrated in the clutch-pedal arrangement, so that, after the response of the signaling and/or protection device to a second operating state, the clutch pedal can be actuated only according to a force/travel characteristic of a second type, which differs significantly from the force/travel characteristic of the first type in order thus to indicate the second operating state.
摘要翻译：布置在驱动单元和变速器之间的驱动线路中的用于摩擦离合器的致动装置。具有用于致动摩擦离合器的致动装置和离合器踏板装置的安装件，其连接到致动装置并且具有离合器踏板，该离合器踏板在第一操作状态下可根据力 - 行程特性致动的第一种类型。致动装置具有信号和/或保护装置，其与离合器踏板装置操作连接或可操作地集成在离合器踏板装置中，使得在信令和/或保护装置响应到第二操作状态之后，离合器踏板只能根据第二类型的力/行驶特性而起动，这与第一类型的力/行驶特性有很大的不同，从而指示第二操作状态。

42. 发明授权

US6029789A Actuating device for actuation, especially pneumatic actuation, of a friction clutch 失效
标题翻译：用于致动，特别是气动致动的用于摩擦离合器的致动装置
公开(公告)号：US6029789A
公开(公告)日：2000-02-29
申请号：US4439
申请日：1998-01-08
申请人： Joachim Lindner , Jorg Willert , Thomas Otto
发明人： Joachim Lindner , Jorg Willert , Thomas Otto
IPC分类号： B60J7/06 , B60K23/02 , F15B13/04 , F16D25/08 , F16D48/02 , B62K23/02
CPC分类号： F16D25/083 , B60K23/02 , F15B13/0406
摘要： A actuating device for a friction clutch which is arranged in the drivetrain of a motor vehicle in a housing cover between an internal combustion engine and a transmission. The actuating device includes a release bearing arrangement and a positioning servo arrangement for the release bearing arrangement. The positioning servo arrangement has a pressure medium power cylinder arrangement and a control valve connected with a pressure medium source. The control valve includes a valve arrangement which is switchable between at least two control states depending on an actual quantity representing the axial position of the release bearing arrangement and on a control quantity representing a reference position of the release bearing arrangement. In a first control state, there is a pressure medium connection between the pressure medium power cylinder arrangement and the pressure medium source, and in a second control state there is a pressure medium connection between the pressure medium power cylinder arrangement and a pressure compensation port. The valve arrangement includes two valve elements which are movable relative to one another and relative to a valve housing. The control quantity is represented by the position of a first valve element of the two valve elements and the actual quantity is represented by the position of a second valve element of the two valve elements relative to the valve housing. A differential quantity associated with the actual quantity and control quantity is represented by the position of the two valve elements relative to one another.
摘要翻译：一种用于摩擦离合器的致动装置，其布置在内燃机和变速器之间的壳体盖中的机动车辆的传动系中。致动装置包括释放轴承装置和用于释放轴承装置的定位伺服装置。定位伺服装置具有压力介质动力缸装置和与压力介质源连接的控制阀。控制阀包括阀装置，其可以根据表示释放轴承装置的轴向位置的实际数量和表示释放轴承装置的基准位置的控制量在至少两个控制状态之间切换。在第一控制状态下，在压力介质动力缸装置和压力介质源之间存在压力介质连接，并且在第二控制状态下，在压力介质动力缸装置和压力补偿端口之间存在压力介质连接。阀装置包括两个可相对于阀壳体移动的阀元件。控制量由两个阀元件的第一阀元件的位置表示，实际量由两个阀元件相对于阀壳体的第二阀元件的位置表示。与实际量和控制量相关联的差分量由两个阀元件相对于彼此的位置表示。

43. 发明授权

US5785691A Syringe cap assembly 失效
标题翻译：注射器帽组件
公开(公告)号：US5785691A
公开(公告)日：1998-07-28
申请号：US724075
申请日：1996-09-30
申请人： Helmut Vetter , Thomas Otto
发明人： Helmut Vetter , Thomas Otto
IPC分类号： A61M5/32 , A61M5/31 , A61M5/34 , A61M5/50
CPC分类号： A61M5/34 , A61M2005/3104 , A61M2005/3106 , A61M2005/312 , A61M5/3134 , A61M5/5086 , Y10S215/03 , Y10S604/905
摘要： A syringe assembly has a syringe body adapted to be filled with an injectable liquid and having an annular neck defining an axis forming an axially outwardly open outlet and a needle insert fitting in and blocking the outlet and formed with an axially throughgoing passage so that a needle can be inserted axially through the passage of the insert into the body. A retaining collar engaged around the neck holds the insert in the outlet and a plug engaged in the passage fits over the retaining collar. A retaining ring fixed around the collar at the neck holds the collar on the neck and has an annular and axially outwardly directed end edge. A cup-shaped safety cap bearing axially inward on the plug has an annular and axially inwardly directed end edge confronting the retaining-ring edge and spaced axially therefrom by a gap which is bridged by a plurality of angularly spaced frangible webs unitarily formed with the ring and with the cap and extending from the cap edge to the ring edge. A plurality of angularly spaced spacer blocks formed on one of the edges and alternating with the webs project at least partially across the gap toward the other edge.
摘要翻译：注射器组件具有适于填充注射液体的注射器主体，并且具有限定形成轴向向外开口的轴线的轴颈的环形颈部和插入并阻塞出口并且形成有轴向穿过通道的针插入件，使得针可以插入轴向通过插入物的通道进入体内。围绕颈部接合的保持环将插入物保持在出口中，并且接合在通道中的插头配合在保持环上。固定在颈部的颈环处的保持环将颈圈保持在颈部上并且具有环形和轴向向外指向的端边缘。在塞子上轴向向内轴承的杯形安全帽具有面向保持环边缘的环形和轴向向内的端部边缘并且与其轴向间隔开间隙，间隙由多个与环形成一体形成的有角度间隔开的易碎卷筒桥接并且具有帽并且从帽边缘延伸到环形边缘。形成在一个边缘上并与腹板交替的多个有角度间隔的间隔块至少部分地跨越间隙突出到另一边缘。

44. 发明授权

US5541298A Method of determining metastatic potential of tumor cells 失效
标题翻译：确定肿瘤细胞转移潜能的方法
公开(公告)号：US5541298A
公开(公告)日：1996-07-30
申请号：US459201
申请日：1995-06-02
申请人： Avraham Raz , Ivan R. Nabi , Hideomi Watanabe , Thomas Otto
发明人： Avraham Raz , Ivan R. Nabi , Hideomi Watanabe , Thomas Otto
IPC分类号： C07H21/04 , C07K14/705 , C07K16/30 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , C12R1/91 , G01N33/574 , C07K14/00
CPC分类号： C07K14/705 , G01N33/57438 , G01N33/57492 , G01N2333/705 , Y10S436/813 , Y10S530/828
摘要： Methods and compositions useful in the detection of human cancer cells and malignant tumors are provided. Certain human autocrine motility factor receptors or proteins (gp78-hAMFR) have been identified which are useful in the detection of human cancer cells and malignant tumors. Methods and assay kits for the detection of human cancer, human cancer cells, and tumors, are provided wherein antibodies or other probes are used which recognize gp78-hAMFR expression. These methods and assay readily distinguish between non-malignant and malignant cancer cells and tumors and can be used to gauge metastatic potential.
摘要翻译：提供了可用于检测人类癌细胞和恶性肿瘤的方法和组合物。已经鉴定了某些人自分泌运动因子受体或蛋白质（gp78-hAMFR），其可用于检测人类癌细胞和恶性肿瘤。提供用于检测人癌，人癌细胞和肿瘤的方法和测定试剂盒，其中使用识别gp78-hAMFR表达的抗体或其它探针。这些方法和测定方法很容易区分非恶性和恶性癌细胞和肿瘤，并可用于测量转移潜能。

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