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41. 发明授权

US08694071B2 Image stabilization techniques and methods 有权
标题翻译：图像稳定技术和方法
公开(公告)号：US08694071B2
公开(公告)日：2014-04-08
申请号：US13025981
申请日：2011-02-11
申请人： Vahid Saadat , Michael J. Drews
发明人： Vahid Saadat , Michael J. Drews
IPC分类号： A61B5/05
CPC分类号： A61B1/00089 , A61B1/00009 , A61B1/0607 , A61B1/0623 , A61B1/126 , A61B5/1114 , A61B5/1128 , A61B2505/05 , A61B2560/0204 , A61B2562/0219 , A61B2562/0233 , A61B2562/245
摘要： Direct optical imaging of anatomical features and structures from within a biological organ in a dynamic environment (where the tissue being imaged is in motion due to cardiac rhythms, respiration, etc) presents certain image stability issues due (and/or related) to the motion of the target structure and may limit the ability of the user to visually interpret the image for the purposes of diagnostics and therapeutics. Systems and mechanisms for the purpose of actively stabilizing the image or for compiling and re-displaying the image information in a manner that is more suitable to interpretation by the user are disclosed.
摘要翻译：在动态环境（其中成像的组织由于心律，呼吸等引起的运动）中的生物器官内的解剖特征和结构的直接光学成像给出了与运动有关（和/或相关）的某些图像稳定性问题的目标结构，并且可能限制用户视觉地解释图像以用于诊断和治疗的能力。公开了用于以更适合于用户解释的方式主动地稳定图像或用于编译和重新显示图像信息的系统和机构。

42. 发明申请

US20130237929A1 SELF-CLOSING DEVICES AND METHODS FOR MAKING AND USING THEM 有权
公开(公告)号：US20130237929A1
公开(公告)日：2013-09-12
申请号：US13607783
申请日：2012-09-09
申请人： James HONG , Michael J. Drews
发明人： James HONG , Michael J. Drews
IPC分类号： A61M25/00
CPC分类号： A61B17/0057 , A61B17/11 , A61B17/3403 , A61B90/39 , A61B2017/00592 , A61B2017/00597 , A61B2017/00676 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/1107 , A61B2017/1135 , A61B2017/12004 , A61B2090/3962 , A61B2090/3966 , A61F2/064 , A61F2210/009 , A61M1/3655 , A61M39/0247 , A61M2039/0258 , A61M2039/0261 , A61M2039/0291
摘要： A self-closing device for implantation within a patient's body includes base material including an inner surface area for securing the base material to a tissue structure, and a plurality of support elements surrounding or embedded in the base material. The support elements are separable laterally within a plane of the base material to accommodate creating an opening through the base material for receiving one or more instruments through the base material, and biased to return laterally towards a relaxed state for self-closing the opening after removing the one or more instruments. The device may be provided as a patch or integrally attached to a tubular graft or in various shapes.

43. 发明授权

US08226664B2 Biological unit removal tools with movable retention member 有权
标题翻译：具有可动保持构件的生物单位拆除工具
公开(公告)号：US08226664B2
公开(公告)日：2012-07-24
申请号：US12403605
申请日：2009-03-13
申请人： Michael J. Drews , Dennis Westerling , Timothy J. Kirkley
发明人： Michael J. Drews , Dennis Westerling , Timothy J. Kirkley
IPC分类号： A61B17/50
CPC分类号： A61B19/50 , A61B10/0266 , A61B17/00 , A61B17/32053 , A61B17/322 , A61B34/10 , A61B34/30 , A61B2017/00752 , A61B2017/32004 , A61B2017/320064
摘要： Tools and methods of use for removing biological units from a body surface utilizing a removal tool are disclosed. The tool incorporates a retention member configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. The retention member is radially movable within the lumen of the biological unit removal tool. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit.
摘要翻译：公开了使用去除工具从身体表面去除生物单元的工具和使用方法。该工具包括保持构件，该保持构件构造成阻止生物单元沿着工具的远端方向的移动，并且改善生物单元在工具中的保留。保持构件可在生物单元去除工具的内腔内径向移动。工具的远侧末端期望配置为减少生物单元横切的机会。

44. 发明授权

US08083793B2 Two piece heart valves including multiple lobe valves and methods for implanting them 有权
标题翻译：两片心脏瓣膜包括多瓣瓣和植入它们的方法
公开(公告)号：US08083793B2
公开(公告)日：2011-12-27
申请号：US11069457
申请日：2005-02-28
申请人： Ernest Lane , Michael J. Drews , Donnell W. Gurskis , Oleg Svanidze
发明人： Ernest Lane , Michael J. Drews , Donnell W. Gurskis , Oleg Svanidze
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2250/006 , A61F2250/0097
摘要： A heart valve assembly including an annular prosthesis implantable within a biological annulus, a prosthetic valve including a multiple lobular shape for implantation above the biological annulus, and one or more connectors for securing the prosthetic valve to the annular prosthesis. A flexible sewing cuff extends radially from the annular prosthesis that is resiliently flexible for conforming to the multiple lobular shape of the prosthetic valve to enhance a seal between the prosthetic valve and the annular prosthesis. The sewing cuff may include a core resiliently conformable with anatomy surrounding the biological annulus and fabric covering at least a portion of the core.
摘要翻译：一种心脏瓣膜组件，包括可植入生物环境内的环形假体，包括用于植入生物环空以上的多个小叶形状的假体瓣和用于将假体瓣固定到环形假体的一个或多个连接器。弹性缝合针从弹性柔性的环形假体径向延伸，以符合人工瓣膜的多个小叶形状，以增强人造瓣膜和环形假体之间的密封。缝合箍可以包括弹性地与包围生物环的解剖结构的芯和覆盖芯的至少一部分的织物。

45. 发明申请

US20100010616A1 ATTACHMENT DEVICE AND METHODS OF USING THE SAME 有权
标题翻译：附件装置及其使用方法
公开(公告)号：US20100010616A1
公开(公告)日：2010-01-14
申请号：US12498195
申请日：2009-07-06
申请人： Michael J. Drews , Donnell W. Gurskis , Steven R. Bacich
发明人： Michael J. Drews , Donnell W. Gurskis , Steven R. Bacich
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61B17/064 , A61B17/0682 , A61B17/083 , A61B17/1227 , A61B2017/0641 , A61F2/2427 , Y10S623/904
摘要： Devices for attaching a first mass and a second mass and methods of making and using the same are disclosed. The devices can be made from an resilient, elastic or deformable materials. The devices can be used to attach a heart valve ring to a biological annulus. The devices can also be used for wound closure or a variety of other procedures such as anchoring a prosthesis to surrounding tissue or another prosthesis, tissue repair, such as in the closure of congenital defects such as septal heart defects, tissue or vessel anastomosis, fixation of tissue with or without a reinforcing mesh for hernia repair, orthopedic anchoring such as in bone fusing or tendon or muscle repair, ophthalmic indications, laparoscopic or endoscopic tissue repair or placement of prostheses, or use by robotic devices for procedures such as those above performed remotely.
摘要翻译：公开了用于附接第一质量块和第二质量块的装置及其制造和使用方法。设备可以由弹性，弹性或可变形材料制成。该装置可用于将心脏瓣膜环附接到生物环。该装置还可以用于伤口闭合或各种其他程序，例如将假体锚定到周围组织或另一假体，组织修复，例如闭合先天性缺陷，例如中隔心脏缺陷，组织或血管吻合，固定具有或不具有用于疝修补的加强网的组织，矫形锚固例如骨融合或肌腱或肌肉修复，眼科适应症，腹腔镜或内窥镜组织修复或假体放置，或由机器人装置用于上述方法远程

46. 发明授权

US07556647B2 Attachment device and methods of using the same 有权
标题翻译：附件装置及其使用方法
公开(公告)号：US07556647B2
公开(公告)日：2009-07-07
申请号：US10681700
申请日：2003-10-08
申请人： Michael J. Drews , Donnell W. Gurskis , Steven R. Bacich
发明人： Michael J. Drews , Donnell W. Gurskis , Steven R. Bacich
IPC分类号： A61F2/24 , A61B17/10 , A61B17/08
CPC分类号： A61B17/064 , A61B17/0682 , A61B17/083 , A61B17/1227 , A61B2017/0641 , A61F2/2427 , Y10S623/904
摘要： Devices for attaching a first mass and a second mass and methods of making and using the same are disclosed. The devices can be made from an resilient, elastic or deformable materials. The devices can be used to attach a heart valve ring to a biological annulus. The devices can also be used for wound closure or a variety of other procedures such as anchoring a prosthesis to surrounding tissue or another prosthesis, tissue repair, such as in the closure of congenital defects such as septal heart defects, tissue or vessel anastomosis, fixation of tissue with or without a reinforcing mesh for hernia repair, orthopedic anchoring such as in bone fusing or tendon or muscle repair, ophthalmic indications, laparoscopic or endoscopic tissue repair or placement of prostheses, or use by robotic devices for procedures such as those above performed remotely.
摘要翻译：公开了用于附接第一质量块和第二质量块的装置及其制造和使用方法。设备可以由弹性，弹性或可变形材料制成。该装置可用于将心脏瓣膜环附接到生物环。该装置还可以用于伤口闭合或各种其他程序，例如将假体锚定到周围组织或另一假体，组织修复，例如闭合先天性缺陷，例如中隔心脏缺陷，组织或血管吻合，固定具有或不具有用于疝修补的加强网的组织，矫形锚固例如骨融合或肌腱或肌肉修复，眼科适应症，腹腔镜或内窥镜组织修复或假体放置，或由机器人装置用于上述方法远程

47. 发明授权

US09750504B2 Embolization device and a method of using the same 有权
公开(公告)号：US09750504B2
公开(公告)日：2017-09-05
申请号：US15372171
申请日：2016-12-07
申请人： Thomas J. Fogarty
发明人： Thomas J. Fogarty , Michael J. Drews , D. Bruce Modesitt , Neil D. Holmgren , David B. Willis
IPC分类号： A61M29/00 , A61B17/12 , A61F2/07 , A61F2/88
CPC分类号： A61B17/12118 , A61B17/12022 , A61B17/12163 , A61F2/07 , A61F2/88 , A61F2002/075 , A61F2220/0091 , A61F2230/001 , A61F2230/0019 , A61F2230/0021 , A61L31/044
摘要： A method of filling an aneurysm space within the abdominal aorta is disclosed. The method involves placing a prosthesis in the abdominal aorta; delivering a fillable bladder in a deflated state into the aneurysm space using a catheter; placing a filler tube in fluid communication with an inflow port of the fillable bladder. The fillable bladder comprises a bladder seal surrounding the fillable bladder and the bladder seal has a first side, a second side, a third side, and a fourth side. The first side is symmetric with the second side with respect to a first axis of the fillable bladder and the third side is symmetric with the fourth side with respect to a second axis of the fillable bladder. The first axis is perpendicular to the second axis. The method further involves filling the fillable bladder with a filling agent and removing the filler tube.

48. 发明授权

US08500755B2 Apparatus and method for delivering fasteners during valve replacement 有权
标题翻译：在更换阀门时提供紧固件的装置和方法
公开(公告)号：US08500755B2
公开(公告)日：2013-08-06
申请号：US12022898
申请日：2008-01-30
申请人： Takashi Harry Ino , Michael J. Drews , Donnell W. Gurskis
发明人： Takashi Harry Ino , Michael J. Drews , Donnell W. Gurskis
IPC分类号： A61B17/10
CPC分类号： A61B17/0644 , A61B17/068 , A61B2017/00862
摘要： A fastener delivery tool includes a loading chamber for receiving a fastener having a pair of tines overlapping one another to define a loop in a parent or relaxed state. A retaining member retains the fastener in the loading chamber. The fastener delivery tool also includes a tongue, pusher member, and an ejection track communicating with the loading chamber. An actuator causes the tongue to move to engage the tines of the fastener to transform the fastener from the relaxed state to a constrained state defining a U-shape. The actuator also causes the pusher member to release the retaining member and advance the fastener down the ejection track in the constrained state. The tool also includes a trigger for ejecting the fastener completely from the ejection track. The fastener may be used to secure a prosthetic heart valve or components thereof into surrounding tissue, e.g., within a tissue annulus.
摘要翻译：紧固件输送工具包括用于接纳紧固件的装载室，所述紧固件具有一对彼此重叠的齿，以限定处于母体或松弛状态的环。保持构件将紧固件保持在装载室中。紧固件输送工具还包括舌头，推动器构件和与装载室连通的排出轨道。致动器使舌头移动以接合紧固件的尖齿，以将紧固件从松弛状态转变为限定U形的约束状态。致动器还使得推动器构件释放保持构件并且在紧固状态下将紧固件向下推出排出轨道。该工具还包括用于从弹出轨道完全弹出紧固件的触发器。紧固件可以用于将假体心脏瓣膜或其部件固定到周围组织中，例如在组织环空中。

49. 发明授权

US08377119B2 Heart valve assemblies 有权
标题翻译：心脏瓣膜组件
公开(公告)号：US08377119B2
公开(公告)日：2013-02-19
申请号：US12574611
申请日：2009-10-06
申请人： Michael J. Drews , Donnell W. Gurskis , Steven R. Bacich
发明人： Michael J. Drews , Donnell W. Gurskis , Steven R. Bacich
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2412 , A61F2250/006 , A61F2250/0097 , A61F2250/0098
摘要： A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
摘要翻译：心脏瓣膜组件包括在平面内包括多小叶状环状的基部，阀构件或包括与基部的形状互补的多小叶形状的其它环形体，以及基部和环形体上的配合连接器，将环形体连接到基座。底座包括一个固定环，和一个用于将基座连接到生物环的柔性箍。基部和环形体包括用于对准其多小叶形状的引导件，例如从底部延伸的视觉，触觉或其它标记或系绳，其可滑动通过环形体。在使用过程中，基座附接到生物环形区域，环形体被定向成邻近环形区域，定向成使得环形体阀构件的多小叶形状与基部对准，并且环形体附接到基部。

50. 发明申请

US20120265217A1 BIOLOGICAL UNIT REMOVAL TOOLS WITH MOVABLE RETENTION MEMBER 有权
标题翻译：具有可移动保持构件的生物单元拆卸工具
公开(公告)号：US20120265217A1
公开(公告)日：2012-10-18
申请号：US13533614
申请日：2012-06-26
申请人： Michael J. Drews , Dennis Westerling
发明人： Michael J. Drews , Dennis Westerling
IPC分类号： A61B17/50
CPC分类号： A61B19/50 , A61B10/0266 , A61B17/00 , A61B17/32053 , A61B17/322 , A61B34/10 , A61B34/30 , A61B2017/00752 , A61B2017/32004 , A61B2017/320064
摘要： Tools and methods of use for removing biological units from a body surface utilizing a removal tool are disclosed. The tool incorporates a retention member configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. The retention member is radially movable within the lumen of the biological unit removal tool. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit.
摘要翻译：公开了使用去除工具从身体表面去除生物单元的工具和使用方法。该工具包括保持构件，该保持构件构造成阻止生物单元沿着工具的远端方向的移动，并且改善生物单元在工具中的保留。保持构件可在生物单元去除工具的内腔内径向移动。工具的远侧末端期望配置为减少生物单元横切的机会。

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