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    • 44. 发明申请
    • PROSTACYCLINES AND PROCESS FOR THEIR PREPARATION
    • 前体制剂及其制备方法
    • WO1984002902A1
    • 1984-08-02
    • PCT/JP1984000018
    • 1984-01-26
    • TEIJIN LIMITEDIKEGAMI, ShiroKUROZUMI, Seizi
    • TEIJIN LIMITED
    • C07C59/46
    • C07C405/0083Y02P20/55
    • Novel prostacyclines represented by the formula (I), wherein ---- between 2- and 3-positions represents that the bond between these positions is a single or double bond, G represents -CO2R5 or -CONR6R7, wherein R5 represents H, C1-C10 alkyl, substituted or unsubstituted alicyclic group, substituted or unsubstituted phenyl-(C1-C2) alkyl group, tri(C1-C10)hydrocarbyl-silyl group or an equivalent cation, R6 and R7 are the same or different and each represents H, C1-C10 alkyl or, when combined together, they represent a 5- or 6-membered, substituted or unsubstituted ring together with the adjacent nitrogen atom optionally containing further hetero atom(s), R1 represents H or methyl, R2 represents unsubstituted C3-C8 alkyl, substituted or unsubstituted alicylic group, or substituted C1-C5 alkyl group substituted by optionally substituted phenyl, phenoxy, C1-C6 alkoxy or C5-C6 cycloalkyl, R3 and R4 are the same or different and each represents H, C2-C7 acyl, tri(C1-C7)hydrocarbyl-silyl, or a group forming an acetal bond together with the oxygen atom of OH. The compounds exhibit excellent pharmacological effects such as blood platelet enticoagulating effect, thus being useful as thrombosis-treating agents, arteriosclerosis-treating agents, etc.
    • 47. 发明申请
    • POWDERY MEDICINE DOSING DEVICE
    • 粉末药物剂量设备
    • WO1997004826A1
    • 1997-02-13
    • PCT/JP1996002097
    • 1996-07-25
    • TEIJIN LIMITEDMATSUGI, HideoKAWABE, HiroyukiMAKINO, YujiSUZUKI, YoshikiFUJII, Takao
    • TEIJIN LIMITED
    • A61M13/00
    • A61M15/0028A61M11/00A61M2202/06A61M2202/064
    • A powdery medicine dosing device which achieves portability, simplicity and rapidity of operation, simplicity of a manufacturing process, rigidity of construction, and economy such as minimization of the number of parts and low costing. The device comprises a medicine holding section, which defines therein a powder medicine storing space doubling as an air reservoir and of which at least a portion of a wall is flexible, and a medicine leading-out section which allows an inner space of the medicine holding section to communicate with the outside. The inner space of the medicine holding section communicates with the outside only through the medicine leading-out section, and the medicine leading-out section is of a tubular construction which includes at one end thereof a medicine spraying port disposed outside of the medicine holding section and at the other end thereof a medicine suction port disposed in the inner space of the medicine holding section. Disposed substantially immediately below the medicine suction port of the medicine leading-out section is a bottom of the inner space of the medicine holding section, and disposed close to the bottom is the medicine suction port, so that a powder medicine is jetted outside through the medicine leading-out section by pressing and loosening the flexible wall portion of the medicine holding section.
    • 实现便携性,操作简单性和快速性,制造过程简单,结构刚性和经济性的粉末药物计量装置,例如零件数量的最小化和低成本。 该装置包括:药剂保持部,其在其中限定作为空气储存器加倍的粉末药物储存空间,壁的至少一部分是柔性的;以及药物引出部,其允许药剂保持的内部空间 部分与外界沟通。 药剂保持部的内部空间仅通过药物引出部与外部连通,药物导出部为管状结构,其一端包括设置在药剂保持部的外侧的药剂喷出口 另一端设置在药剂保持部的内部空间中的吸药口。 在药物引出部的药液吸入口的下方大致立即设置在药剂保持部的内部空间的底部,并且靠近底部设置有药物吸入口,从而将粉末药物通过 通过按压和松开药物保持部的柔性壁部来进行药物导出部。
    • 48. 发明申请
    • CELLULOSE ACETATE FIBER HAVING NONCIRCULAR SECTION, ASSEMBLY THEREOF, AND PROCESS FOR PREPARING THE SAME
    • 具有非磁性部分的纤维素乙酸酯纤维,其组装及其制备方法
    • WO1996035010A1
    • 1996-11-07
    • PCT/JP1996001187
    • 1996-04-30
    • TEIJIN LIMITEDMORI, HiroyukiNOSE, Kenkichi
    • TEIJIN LIMITED
    • D01F02/30
    • D01D5/253D01F2/30Y10T428/2973Y10T428/2975Y10T428/2978
    • A cellulose acetate fiber having excellent gloss and hand and comprising a mixture consisting essentially of (a): 100 parts by weight of cellulose acetate with (b) 5 to 40 parts by weight of a polymer material capable of plasticizing the cellulose acetate, wherein the section perpendicular to the longitudinal direction (i) is noncircular, (ii) has one to four symmetrical axes, and (iii) has a peripheral section defined by a gentle curve or a combination of a gentle curve with a straight line. The fiber can be prepared by dry-spinning a spinning solution consisting essentially of: (a) 100 parts by weight of cellulose acetate, (b) 5 to 40 parts by weight of a polymer material which is soluble in solvents and can plasticize the cellulose acetate, and (c) a solvent capable of dissolving the components (a) and (b).
    • 具有优异光泽度和手感的乙酸纤维素纤维,其包含基本上由(a)组成的混合物:100重量份的乙酸纤维素与(b)5至40重量份的能够使乙酸纤维素增塑的聚合物材料,其中 垂直于纵向方向(i)的截面是非圆形的,(ii)具有一至四个对称轴,(iii)具有由平缓曲线限定的外围部分或平缓曲线与直线的组合。 纤维可以通过干纺纺丝溶液来制备,纺丝溶液基本上由以下组成:(a)100重量份的乙酸纤维素,(b)5至40重量份可溶于溶剂的聚合物材料,并且可以增塑纤维素 乙酸酯,(c)能溶解成分(a)和(b)的溶剂。