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41. 发明申请

US20070110962A1 Three-dimensional gels that have microscale features 审中-公开
标题翻译：具有微尺度特征的三维凝胶
公开(公告)号：US20070110962A1
公开(公告)日：2007-05-17
申请号：US10572987
申请日：2004-09-23
申请人： Joe Tien , Min Tang , Andrew Golden
发明人： Joe Tien , Min Tang , Andrew Golden
IPC分类号： B32B3/00
CPC分类号： B81C1/0046 , A61K9/0097 , B81B2201/0214 , B81B2201/06 , B81C99/0085 , B81C2201/0153 , B82Y30/00 , Y10T428/24479 , Y10T428/24612
摘要： The present invention provides three-dimensional hydrogel structures patterned by a treated micropattern mold. The treated mold is capable of transferring the inverse of its micropattern to a hydrogel by contact during formation or polymerization of the structure from a precursor. The treated micropattern mold surface allows the mold to be separated from the hydrogel without collapsing the structure or irreparably damaging its micropattern. The transferred micropattern may yield individual features and/or interconnected channels in the hydrogel. The invention also provides a hydrogel network fabricated by interfacing at least two hydrogels in which one or more of the hydrogels may be a micropatterned structure. Micropatterned hydrogel structures can also be specifically aligned to interconnect their patterns. Structures or networks of the invention comprise hydrogels that can adhere together by chemically bonding and/or mechanically entangling.
摘要翻译：本发明提供了通过处理的微图案模具图案化的三维水凝胶结构。经处理的模具能够在从前体形成或聚合结构期间通过接触将其微图案的倒数转移到水凝胶。经处理的微图案模具表面允许模具与水凝胶分离，而不会破坏结构或不可修复地损坏其微图案。转移的微图案可以在水凝胶中产生单个特征和/或互连通道。本发明还提供了一种水凝胶网络，其通过与至少两个水凝胶接合而制造，其中一个或多个水凝胶可以是微图案结构。微图案化的水凝胶结构也可以特别对准以互连其图案。本发明的结构或网络包括可通过化学键合和/或机械缠结而粘合在一起的水凝胶。

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