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41. 发明申请

US20100016689A1 METHOD FOR NONINVASIVE MEASUREMENT OF GLUCOSE AND APPARATUS FOR NONINVASIVE MEASUREMENT OF GLUCOSE 有权
标题翻译：葡萄糖非葡萄糖测定方法及非葡萄糖测定方法
公开(公告)号：US20100016689A1
公开(公告)日：2010-01-21
申请号：US12418899
申请日：2009-04-06
申请人： Shoichi Kanayama , Omar S. KHALIL , Tzyy-Wen JENG , Shu-Jen YEH
发明人： Shoichi Kanayama , Omar S. KHALIL , Tzyy-Wen JENG , Shu-Jen YEH
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/0053 , A61B5/14532 , A61B5/1491 , A61B5/1495 , A61B5/6824 , A61B5/6843
摘要： A method for noninvasive measurement of glucose in a tissue of a subject, including the steps of bringing an adaptation device, which has a shape similar to a measurement probe, into contact with a skin part of a subject for stretching the skin part of the subject under a pressure that is higher than a pressure per unit area applied by the measurement probe during the noninvasive measurement, maintaining the contact for a predetermined period of time followed by relieving the contact, bringing the measurement probe into contact with the stretched skin part of the subject for the noninvasive measurement, collecting signals emitted from the subject, and estimating a glucose concentration based on the collected signals.
摘要翻译：一种用于对受试者的组织中的葡萄糖进行非侵入性测量的方法，包括以下步骤：将具有与测量探针类似的形状的适应装置与受试者的皮肤部分接触以拉伸受试者的皮肤部分在非侵入性测量期间高于测量探针施加的每单位面积的压力的压力下，将接触保持预定的时间段，然后释放接触，使测量探针与被拉伸的皮肤部分接触主观无创测量，收集从受试者发射的信号，并根据收集的信号估计葡萄糖浓度。

42. 发明申请

US20090009760A1 AUTOMATIC ANALYSIS APPARATUS AND AUTOMATIC ANALYSIS METHOD 有权
标题翻译：自动分析装置及自动分析方法
公开(公告)号：US20090009760A1
公开(公告)日：2009-01-08
申请号：US12168763
申请日：2008-07-07
申请人： Shoichi Kanayama , Naoko Omuro
发明人： Shoichi Kanayama , Naoko Omuro
IPC分类号： G01J3/443
CPC分类号： G01N21/253 , G01N21/534
摘要： An automatic analysis apparatus and an automatic analysis method that can perform both spectrophometric measurements for biochemical tests and the turbidimetric immunoassay with high precision by selectively exchanging a white light or at least one monochromatic light based on analysis conditions determined by a measure condition setting unit for respective measuring object. The automatic analysis apparatus includes an irradiating direction setting unit configured to irradiate the selected white light or at least one monochromatic light based on the analysis conditions onto a reaction cuvette along the same light axis and a light detection unit having a plurality of light receiving elements in order to detect the white light of particular determined wavelength lights and the selected monochromatic light.
摘要翻译：一种自动分析装置和自动分析方法，其可以基于由各自的测量条件设定单元确定的分析条件，通过选择性地交换白光或至少一个单色光，以高精度执行生化测试和比浊免疫测定两种分光测量测量对象。自动分析装置包括：照射方向设定单元，被配置为基于分析条件将所选择的白光或至少一个单色光沿着相同的光轴照射到反应容器上;以及光检测单元，其具有多个光接收元件以检测特定确定的波长光和所选择的单色光的白光。

43. 发明申请

US20090004060A1 MICRO-CHEMICAL ANALYSIS DEVICE, MICROCHEMICAL MEASURING METHOD, AND SAMPLE COLLECTING TOOL 有权
标题翻译：微量化学分析装置，微观测量方法和样品收集工具
公开(公告)号：US20090004060A1
公开(公告)日：2009-01-01
申请号：US12164371
申请日：2008-06-30
申请人： Naoko Omuro , Shoichi Kanayama
发明人： Naoko Omuro , Shoichi Kanayama
IPC分类号： G01N33/49 , G01N1/14
CPC分类号： G01N35/00029 , A61B5/150022 , A61B5/15003 , A61B5/150221 , A61B5/150236 , A61B5/150244 , A61B5/150343 , A61B5/150389 , A61B5/150503 , A61B5/150587 , A61B5/150717 , A61B5/150755 , A61B5/15087 , A61B5/153 , A61B5/157 , B01L3/502715 , B01L2200/027 , B01L2200/10 , B01L2300/0654 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2400/0409 , B01L2400/0478 , G01N33/49 , Y10T436/11 , Y10T436/2575
摘要： A micro-cassette 1 stores a sample, a reagent, and an additive, and comprises a sensor measures the component of measurement item. Analysis device 2 comprises liquid control unit controls each liquid in micro-cassette 1. Mixing controller 33 mixes the sample and the additive sent to sample processing unit 13, and generates the first sample includes a formed element. Isolation unit 14 generates the second sample from the first sample sent from sample processing unit 13. Sensor 18 measures the compound liquid of the second sample and reagent, and generates the analysis signal.
摘要翻译：微型盒1存储样品，试剂和添加剂，并且包括传感器测量测量项目的组分。分析装置2包括液体控制单元控制微盒1中的每个液体。混合控制器33将样品和送到样品处理单元13的添加剂混合，并且生成第一样品包括成形元件。隔离单元14从从样品处理单元13发送的第一样品产生第二样品。传感器18测量第二样品和试剂的复合液体，并产生分析信号。

44. 发明申请

US20060079741A1 Living body information measuring apparatus 有权
公开(公告)号：US20060079741A1
公开(公告)日：2006-04-13
申请号：US11287250
申请日：2005-11-28
申请人： Shoichi Kanayama
发明人： Shoichi Kanayama
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/14532
摘要： A living body information measuring apparatus includes an optical system for irradiating light to a subject and detecting light from the subject, a signal processing portion for acquiring information with regard to a tissue condition of the subject based on a detecting signal of light, and a position determining portion for determining an acceptability of an irradiating position of light based on the detecting signal of light.

45. 发明授权

US6076004A Magnetic resonance image correction method and magnetic resonance imaging apparatus using the same 失效
标题翻译：磁共振图像校正方法和使用其的磁共振成像装置
公开(公告)号：US6076004A
公开(公告)日：2000-06-13
申请号：US708667
申请日：1996-09-05
申请人： Shoichi Kanayama , Arturo Calderon
发明人： Shoichi Kanayama , Arturo Calderon
IPC分类号： A61B5/055 , G01R33/56 , G06T1/00
CPC分类号： A61B5/7257 , A61B5/055 , G01R33/56 , G01R33/5608 , Y10S128/92 , Y10S128/922
摘要： Cross-correlation between a first magnetic resonance image as a reference image and a second magnetic resonance image to be adjusted relative to the first magnetic resonance image is taken, deviation of the second magnetic resonance image to the first magnetic resonance image as correction values is calculated, and the second magnetic resonance image based on the correction values is corrected.
摘要翻译：将作为参考图像的第一磁共振图像与要相对于第一磁共振图像进行调整的第二磁共振图像之间的相互关系作为校正值计算第二磁共振图像与第一磁共振图像的偏差并且校正基于校正值的第二磁共振图像。

46. 发明授权

US06002254A Method and apparatus for nuclear magnetic resonance imaging of physiological function information 失效
标题翻译：生理功能信息核磁共振成像的方法和装置
公开(公告)号：US06002254A
公开(公告)日：1999-12-14
申请号：US16267
申请日：1998-01-30
申请人： Yoshimori Kassai , Shoichi Kanayama , Shigehide Kuhara , Arturo Calderon
发明人： Yoshimori Kassai , Shoichi Kanayama , Shigehide Kuhara , Arturo Calderon
IPC分类号： G01R33/48 , A61B5/055 , G01R33/56 , G01R33/563 , G01V3/00
CPC分类号： G01R33/4806 , G01R33/5616 , G01R33/563
摘要： A nuclear magnetic resonance imaging scheme suitable for an imaging of a physiological function information on a living body. The scheme uses a pulse sequence for realizing a first imaging scheme for obtaining the blood vessel image and a second imaging scheme for obtaining the physiological function image such as a brain function image by a single execution of the pulse sequence, where the first imaging scheme is executed before the second imaging scheme by controlling resolutions and imaging regions for the respective imaging schemes appropriately. The pulse sequence can also realize a third imaging scheme for obtaining the physical shape image, which is to be executed between the first imaging scheme and the second imaging scheme. The physiological function image can be obtained by selecting valid data from the image data acquired with/without stimulation or load by using the t-test, and determining active portions from the selected valid data by using the paired t-test. The physiological function image can then be displayed in superposition with the blood vessel image and/or the physical shape image.
摘要翻译：一种核磁共振成像方案，适用于对生物体的生理功能信息的成像。该方案使用脉冲序列来实现用于获得血管图像的第一成像方案和用于通过单次执行脉搏序列来获得诸如脑功能图像的生理功能图像的第二成像方案，其中第一成像方案是通过适当地控制各个成像方案的分辨率和成像区域，在第二成像方案之前执行。脉冲序列还可以实现用于获得在第一成像方案和第二成像方案之间执行的物理形状图像的第三成像方案。可以通过使用t检验从通过或不使用刺激或负载获取的图像数据中选择有效数据，并且通过使用配对t检验从选择的有效数据中确定活动部分来获得生理功能图像。然后可以与血管图像和/或物理形状图像重叠显示生理功能图像。

47. 发明授权

US5869964A Magnetic resonance imaging apparatus in which gradient echo signals are acquired at a time distant from the center of a gradient echo 失效
标题翻译：在远离梯度回波中心的时间获取梯度回波信号的磁共振成像装置
公开(公告)号：US5869964A
公开(公告)日：1999-02-09
申请号：US780898
申请日：1997-01-09
申请人： Shigehide Kuhara , Shoichi Kanayama
发明人： Shigehide Kuhara , Shoichi Kanayama
IPC分类号： G01R33/48 , G01R33/561 , G01R33/563 , G01V3/00
CPC分类号： G01R33/5615 , G01R33/563 , G01R33/4806 , G01R33/5618
摘要： A magnetic resonance imaging apparatus capable of obtaining a brain functional image without spending much time and of facillitating to distinguish a vein portion from a cortex portion. The magnetic resonance imaging apparatus includes: a first unit which acquires at least one of data emphasizing a signal from a blood portion in a region of interest in a biological body to be examined and data least affected by inhomogeneity of a static magnetic field; a second unit which acquires data in which a change of magnetic field inhomogeneity (T.sub.2 *) in the region of interest is emphasized; and a control unit which executes simultaneously the first acquiring unit and the second acquiring unit during a predetermined pulse sequence after a radio-frequency magnetic field is applied to the biological body.
摘要翻译：一种磁共振成像装置，其能够获得大脑功能图像，而不花费大量的时间并且能够将静脉部分与皮质部分区分开。磁共振成像装置包括：第一单元，其获取强调来自所检查的生物体中的感兴趣区域中的血液部分的信号的数据和受到静态磁场的不均匀性影响的数据中的至少一个; 获取其中强调感兴趣区域中的磁场不均匀性（T2 *）的变化的数据的第二单元; 以及控制单元，其在对生物体施加射频磁场之后的预定脉冲序列期间同时执行第一获取单元和第二获取单元。

48. 发明授权

US5565777A Method/apparatus for NMR imaging using an imaging scheme sensitive to inhomogeneity and a scheme insensitive to inhomogeneity in a single imaging step 失效
标题翻译：使用对不均匀性敏感的成像方案的NMR成像的方法/装置和在单个成像步骤中对不均匀性不敏感的方案
公开(公告)号：US5565777A
公开(公告)日：1996-10-15
申请号：US305453
申请日：1994-09-13
申请人： Shoichi Kanayama , Shigehide Kuhara
发明人： Shoichi Kanayama , Shigehide Kuhara
IPC分类号： A61B5/055 , G01R33/465 , G01R33/48 , G01R33/563 , G01V3/02 , A61B5/0265
CPC分类号： G01R33/563 , G01R33/465 , G01R33/4806
摘要： A nuclear magnetic resonance imaging scheme for imaging living body information related to the physiological function change in the living body. In this scheme, the pulse sequence realizes a first imaging scheme sensitive to functional information of the body to be examined and a second imaging scheme insensitive to the functional information of the body to be examined so as to obtain first and second types of the nuclear magnetic resonance images corresponding to the first and second imaging schemes, respectively, by a single execution of this pulse sequence. The functional information of the body to be examined is then obtained by processing the first and second types of the nuclear magnetic resonance images.
摘要翻译：一种用于对与身体的生理功能变化相关的生物体信息进行成像的核磁共振成像方案。在该方案中，脉冲序列实现对要检查的身体的功能信息敏感的第一成像方案和对被检体的功能信息不敏感的第二成像方案，以获得第一和第二类型的核磁通过单次执行该脉冲序列，分别对应于第一和第二成像方案的共振图像。然后通过处理第一和第二类型的核磁共振图像来获得被检体的功能信息。

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