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41. 发明申请

WO2018060024A1 A MEDICAMENT DELIVERY DEVICE 审中-公开
标题翻译：药物输送装置
公开(公告)号：WO2018060024A1
公开(公告)日：2018-04-05
申请号：PCT/EP2017/073722
申请日：2017-09-20
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , FRANKE, Beate , PRADEL, Giuliano , MELZI, Ilario , VERLAAK, Stefan , NELSON, Andrew
IPC分类号： A61M5/148 , A61M5/20 , A61M5/142 , A61M5/145
摘要： The present invention relates to a medicament delivery device comprising a housing, a reservoir for medicament disposed in the housing and a dispensing member. The dispensing member is moveable relative to the housing from a first position to a second position to dispense medicament from the reservoir when the reservoir contains medicament. The medicament delivery device further comprises first and second biasing members. The first biasing member is configured to urge the dispensing member from the first position to an intermediate position. The second biasing member is configured to urge the dispensing member from the intermediate position to the second position.
摘要翻译：药物输送装置技术领域本发明涉及一种药物输送装置，该药物输送装置包括壳体，布置在壳体中的用于药物的储存器和分配构件。分配构件可相对于壳体从第一位置移动到第二位置，以在储存器容纳药物时从储存器分配药物。药物输送装置还包括第一和第二偏置构件。第一偏压构件构造成将分配构件从第一位置推压到中间位置。第二偏压构件构造成将分配构件从中间位置推压到第二位置。

42. 发明申请

WO2018028915A1 MEDICAMENT DELIVERY DEVICE 审中-公开
标题翻译：药物输送装置
公开(公告)号：WO2018028915A1
公开(公告)日：2018-02-15
申请号：PCT/EP2017/067512
申请日：2017-07-12
申请人： SANOFI
发明人： SCHABBACH, Michael , FRANKE, Beate , PRADEL, Giuliano , NELSON, Andrew
IPC分类号： A61M5/20 , A61M5/32 , A61M5/24
摘要： A medicament delivery device comprises a device housing for placing on the skin of a patient, the housing comprising a needle aperture; a needle for injecting a medicament, the needle arranged to pass through the needle aperture; and a plurality of sensors configured to provide a signal when the housing is placed on the skin of the patient, wherein the sensors are arranged around the needle aperture.
摘要翻译：药物输送装置包括用于放置在患者皮肤上的装置壳体，所述壳体包括针孔; 用于注射药剂的针，所述针布置成穿过针孔; 以及多个传感器，所述多个传感器被配置成当外壳放置在患者的皮肤上时提供信号，其中传感器围绕针孔布置。

43. 发明申请

WO2017021229A1 SENSOR, CARTRIDGE AND DRUG DELIVERY DEVICE 审中-公开
标题翻译：传感器，药盒和药物递送装置
公开(公告)号：WO2017021229A1
公开(公告)日：2017-02-09
申请号：PCT/EP2016/067815
申请日：2016-07-26
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , NESSEL, Christian , AUERNHAMMER, Daniel , FRANKE, Beate , SOARES, Francisco
IPC分类号： A61M5/24 , G01F23/26 , A61M5/145 , A61M5/168 , A61M5/20 , G01F23/00
CPC分类号： A61M5/24 , A61M5/1452 , A61M5/1684 , A61M5/20 , A61M2205/3317 , A61M2205/3368 , A61M2205/3389 , A61M2205/52 , A61M2205/8212 , A61M2205/8243 , A61M2205/8293 , G01F23/00 , G01F23/268
摘要： In one aspect the present invention relates to a sensor for measuring at least one physical or chemical parameter of a cartridge (10) or syringe filled with a liquid substance. In further aspects the invention relates to a cartridge (10) equipped with such a sensor as well as to a drug delivery device (1, 2, 3) equipped with such a cartridge (10), wherein the sensor comprises: a planar flexible foil (101) arrangeable to an outer circumference of a barrel (11) of the cartridge (10) or syringe, at least a first and a second measuring electrode (102, 104) arranged on said foil (101), and at least a first and a second contact electrode (106; 108) arranged on said foil (101), wherein the first contact electrode (106) is connected to the first measuring electrode (102) and wherein the second contact electrode (108) is connected to the second measuring electrode (104).
摘要翻译：一方面，本发明涉及用于测量填充有液体物质的盒（10）或注射器的至少一个物理或化学参数的传感器。在另外的方面，本发明涉及配备有这种传感器的盒（10）以及配备有这种盒（10）的药物输送装置（1,2,3），其中传感器包括：平面柔性箔（101），布置在所述盒（10）或注射器的筒体（11）的外圆周上，至少布置在所述箔片（101）上的第一和第二测量电极（102,104），以及至少第一以及布置在所述箔（101）上的第二接触电极（106; 108），其中所述第一接触电极（106）连接到所述第一测量电极（102），并且其中所述第二接触电极（108）连接到所述第二接触电极测量电极（104）。

44. 发明申请

WO2015181187A1 DOSE INDICATING MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置和药物递送装置的剂量指示机构
公开(公告)号：WO2015181187A1
公开(公告)日：2015-12-03
申请号：PCT/EP2015/061619
申请日：2015-05-27
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael
IPC分类号： A61M5/19 , A61M5/24 , A61M5/31
CPC分类号： A61M5/31551 , A61M5/2448 , A61M5/31585 , A61M15/0068 , A61M15/0073 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126
摘要： The invention is directed to a dose indicating mechanism for drug delivery device (1) configured for the delivery of a medicament contained in single medicament cartridge (2), the medicament comprising at least one first drug and one second drug, wherein the dose indicating mechanism comprises a body (3), a dose dial component (7) configured to move relative to the body (3) during dose setting and first dose indicator means (10) configured to display a set dose of the medicament and/or of first drug in dependence of the displacement of dose dial component (7) during dose setting, In order to provide the user with further information, a second dose indicator means (15) is provided that is configured to display a set dose of the second drug during dose setting. The invention is also directed to a respective drug delivery device.
摘要翻译：本发明涉及用于药物输送装置（1）的剂量指示机构，其被配置用于递送包含在单个药剂盒（2）中的药物，所述药物包含至少一种第一药物和一种第二药物，其中所述剂量指示机制包括身体（3），配置成在剂量设定期间相对于身体（3）移动的剂量拨号组件（7）和构造成显示药物和/或第一药物的设定剂量的第一剂量指示器装置（10）根据剂量设定期间剂量拨打组件（7）的位移，为了向用户提供进一步的信息，提供第二剂量指示装置（15），其被配置为在剂量期间显示第二药物的设定剂量设置。本发明还涉及各自的药物递送装置。

45. 发明申请

WO2015121276A1 RESERVOIR FOR LIQUID MEDICAMENT 审中-公开
标题翻译：液体药物储备
公开(公告)号：WO2015121276A1
公开(公告)日：2015-08-20
申请号：PCT/EP2015/052822
申请日：2015-02-11
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , AUERNHAMMER, Daniel , WAGNER, Daniel , KÜHN, Bernd , KLEIN, Isabel , WEISS, Pierre , SCHEPERS, Klaus , MISCHO, Horst
IPC分类号： A61J1/06 , A61M5/28 , A61M5/00 , B65D81/30 , A61M5/31 , A61J1/14
CPC分类号： A61J1/1468 , A61J1/035 , A61J1/05 , A61J1/067 , A61J1/18 , A61M5/002 , A61M5/14
摘要： The present invention relates a reservoir for a liquid medicament, comprising: - a first boundary portion (14; 24; 34; 44; 54) and a second boundary portion (16; 26; 36; 46; 56) forming at least one cavity (12; 22; 32; 42; 52) to receive the medicament (11), - wherein the first boundary portion (14; 24; 34; 44; 54) is flexible, wherein the second boundary portion (16; 26; 36; 46; 56) is rigid, and - wherein at least one of the first and second boundary portions (14, 16; 24, 26; 34, 36; 44, 46; 54, 56) is a transparent boundary portion covered by an opaque cover (18; 28; 38; 48; 58) which is at least partially detachable from the transparent boundary portion.
摘要翻译：本发明涉及一种用于液体药物的储存器，包括： - 第一边界部分（14; 24; 34; 44; 54）和形成至少一个空腔的第二边界部分（16; 26; 36; 46; 56）（12; 22; 32; 42; 52）以接纳药物（11），其中第一边界部分（14; 24; 34; 44; 54）是柔性的，其中第二边界部分 ; 46; 56）是刚性的，并且其中所述第一和第二边界部分（14,16; 24,26; 34,36; 44,46; 54,56）中的至少一个是透明的边界部分，不透明盖（18; 28; 38; 48; 58），其至少部分地可从透明边界部分拆卸。

46. 发明申请

WO2015032740A1 DRIVE MECHANISM FOR A NEEDLE INSERTION ARRANGEMENT 审中-公开
标题翻译：针刺装置的驱动机构
公开(公告)号：WO2015032740A1
公开(公告)日：2015-03-12
申请号：PCT/EP2014/068594
申请日：2014-09-02
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , WERNER, Meinolf , ZECKAI, Olaf
IPC分类号： A61M5/142 , A61M5/32 , A61M5/20 , A61M5/158
CPC分类号： A61M5/3287 , A61M5/158 , A61M5/34 , A61M2005/1585
摘要： The invention relates to a drive mechanism (9) for a needle insertion arrangement (1), the drive mechanism (9) being arranged as a bistable mechanism with at least one pivoted link (10, 11) having two stable end positions (LEP, UEP) and an instable transitional central position (CP), the drive mechanism (9) further comprising a spring (12) biasing the link (10, 11) out of the transitional central position (CP), wherein at least one trigger unit (17, 21) is arranged for moving the link (10, 11) out of at least one of the stable end positions (LEP, UEP) towards and beyond the transitional central position (CP) against the bias of the spring (12).
摘要翻译：本发明涉及一种用于针插入装置（1）的驱动机构（9），驱动机构（9）被布置为具有至少一个具有两个稳定端部位置（LEP， UEP）和不稳定的过渡中心位置（CP），所述驱动机构（9）还包括将所述连杆（10,11）偏离过渡中心位置（CP）的弹簧（12），其中至少一个触发器单元 17,21）被布置成克服弹簧（12）的偏压，将连杆（10,11）从稳定的端部位置（LEP，UEP）中的至少一个朝向和超过过渡中心位置（CP）移动。

47. 发明申请

WO2014023763A1 PEN-TYPE DRUG INJECTION DEVICE AND ELECTRONIC ADD-ON MONITORING MODULE FOR|MONITORING AND LOGGING DOSE SETTING AND ADMINISTRATION 审中-公开
标题翻译：笔式药物注射装置和电子附加监测模块|监测和记录剂量设定和管理
公开(公告)号：WO2014023763A1
公开(公告)日：2014-02-13
申请号：PCT/EP2013/066543
申请日：2013-08-07
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： SCHABBACH, Michael , KÜHN, Bernd
IPC分类号： A61M5/24 , A61M5/315 , A61M5/31 , A61B5/145 , G06F19/00
CPC分类号： A61M5/31525 , A61B5/14532 , A61B5/4836 , A61B5/4839 , A61M5/24 , A61M5/31535 , A61M5/31551 , A61M5/3157 , A61M2005/3125 , A61M2005/3126 , A61M2005/3142 , A61M2205/3306 , A61M2205/3317 , A61M2205/3375 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2205/583 , A61M2209/04 , G06F19/00 , G06F19/3468
摘要： Pen-type drug injection device and electronic add-on monitoring module for monitoring and logging dose setting and administration is described. The module comprises a processor and a sensor (e.g. optical or electromagnetic) for determining the quantity of medicament that has been delivered, wherein the sensor (201, 204) is arranged to detect movement of a drive screw (205) of the injection device during medicament delivery.
摘要翻译：描述了用于监测和记录剂量设定和管理的笔式药物注射装置和电子附加监测模块。该模块包括处理器和用于确定已经被输送的药物的量的传感器（例如光学或电磁），其中传感器（201,204）被布置成检测注射装置的驱动螺杆（205）的运动，药物输送。

48. 发明申请

WO2012055771A1 MEDICINE DELIVERY DEVICE 审中-公开
标题翻译：医药交付设备
公开(公告)号：WO2012055771A1
公开(公告)日：2012-05-03
申请号：PCT/EP2011/068388
申请日：2011-10-21
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , NZIKE, Philippe , SCHABBACH, Michael
发明人： NZIKE, Philippe , SCHABBACH, Michael
IPC分类号： A61M5/142 , A61M5/145
CPC分类号： A61M5/1452 , A61M5/14216
摘要： The invention relates to an apparatus (2) comprising a first piezoelectric actuator (4) comprising a shaft (8), the first piezoelectric actuator (4) being configured to generate a reciprocating movement of the shaft (8) for rotating a piston (10) at least unidirectionally; the piston (10) comprising a stopper (12) being configured to deliver a medicine from a medicine container (14); and a clutch (18) in contact with the piston (10); the clutch (18) being configured to translate the rotational movement of the piston (10) into a translational movement of the piston (10) in a forward direction for delivering the medicine from the medicine container (14); and the clutch (18) being configured to enable a backward movement of the piston (10) in case a force applied to the piston (10) in a backward direction exceeds a predefined value. The invention further relates to a method for delivering medicine and enabling refilling of a medicine container of the apparatus.
摘要翻译：本发明涉及一种包括第一压电致动器（4）的装置（2），所述第一压电致动器（4）包括轴（8），所述第一压电致动器（4）构造成产生所述轴（8）的往复运动，）至少单向; 所述活塞（10）包括用于从药剂容器（14）输送药物的止动件（12）。和与活塞（10）接触的离合器（18）; 离合器（18）构造成将活塞（10）的旋转运动转换成活塞（10）沿向前方向的平移运动，用于从药物容器（14）输送药物; 并且所述离合器（18）构造成在向后方向施加到所述活塞（10）的力超过预定值的情况下能够使所述活塞（10）向后移动。本发明还涉及一种用于输送药物并使得能够对该装置的药物容器进行再充填的方法。

49. 发明申请

WO2010149736A1 PREFILLED CANNULA ASSEMBLY 审中-公开
标题翻译：预制肛门组件
公开(公告)号：WO2010149736A1
公开(公告)日：2010-12-29
申请号：PCT/EP2010/058988
申请日：2010-06-24
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , SCHABBACH, Michael , WAGNER, Daniel , HAUCK, Gerrit
发明人： SCHABBACH, Michael , WAGNER, Daniel , HAUCK, Gerrit
IPC分类号： A61M5/24
CPC分类号： A61M5/2448 , A61M5/282 , A61M2005/1787
摘要： A method and system for proving a cannula arrangement (4) for an injection device. The cannula arrangement comprises a limiting element (16) and a housing configured to attach to the injection device. The housing and the limiting element define a compressible reservoir (40). A second medication (26) is provided in the reservoir. A first cannula (12) comprises a piercing end (20) configured for fluid engagement with a medication provided in the injection device and a distal end (22) configured for fluid engagement with the reservoir. A second cannula (14) comprises a proximal end (48) for fluid engagement with the second medication and a piercing distal end (50) for the injection to a patient.
摘要翻译：一种用于证明注射装置的插管装置（4）的方法和系统。插管装置包括限制元件（16）和构造成附接到注射装置的壳体。壳体和限制元件限定可压缩储存器（40）。第二药物（26）设置在储存器中。第一插管（12）包括构造成与设置在注射装置中的药物流体接合的穿刺端（20）和构造成与储存器流体接合的远端（22）。第二套管（14）包括用于与第二药物流体接合的近端（48）和用于向患者注射的穿刺远端（50）。

50. 发明申请

WO2023078861A1 SUPPLEMENTARY DEVICE WITH INTEGRATED LOCKING MECHANISM 审中-公开
公开(公告)号：WO2023078861A1
公开(公告)日：2023-05-11
申请号：PCT/EP2022/080417
申请日：2022-11-01
申请人： SANOFI
发明人： ALT, Stefan , GLÄSSER, Tim , HELMER, Michael , MÜCKE, Stephan , NOBER, Peter , SCHABBACH, Michael , VITT, Martin
IPC分类号： A61M5/315
摘要： The present disclosure relates to a supplementary device (100) for attaching to a drug delivery device (1), wherein the drug delivery device is operable to set and to dispense a dose of a medicament, the supplementary device (100) comprising: a fastener (103) configured to fasten to a first component (12) of the drug delivery device (1), a control element (104) configured to engage with a second component (13) of the drug delivery device (1), the control element (104) being movable relative to the fastener (103) for inducing a movement of the second component (13) relative to the first component (12) when the fastener (103) is attached to the first component (12), an electronic unit (70) comprising a processor (72), a locking mechanism (150; 250) comprising an electromechanical actuator (151; 251) controllable by the processor (72) and operable to block or to impede a movement of the control element (104) relative to the fastener (103).

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