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41. 发明申请

US20110225475A1 LOW OVERHEAD AND TIMING IMPROVED ARCHITECTURE FOR PERFORMING ERROR CHECKING AND CORRECTION FOR MEMORIES AND BUSES IN SYSTEM-ON-CHIPS, AND OTHER CIRCUITS, SYSTEMS AND PROCESSES 有权
标题翻译：低成本和时序改进的架构，用于执行错误检查和校正系统中的记忆和业务，以及其他电路，系统和过程
公开(公告)号：US20110225475A1
公开(公告)日：2011-09-15
申请号：US12774861
申请日：2010-05-06
申请人： Sanjay Kumar , Amit Kumar Dutta , Rubin A. Parekhji , Srivaths Ravi
发明人： Sanjay Kumar , Amit Kumar Dutta , Rubin A. Parekhji , Srivaths Ravi
IPC分类号： G11C8/06 , H03M13/05 , G06F11/10
CPC分类号： G06F11/1008 , G06F11/1052 , G11C8/06 , G11C8/16 , G11C29/42 , G11C2029/0411 , H03M13/19
摘要： An electronic circuit (200) for use with an accessing circuit (110) that supplies a given address and a partial write data portion and also has dummy cycles. The electronic circuit (200) includes a memory circuit (230) accessible at addresses, an address buffer (410), a data buffer (440) coupled to the memory circuit (230), and a control circuit (246) operable in the dummy cycles to read data from the memory circuit (230) to the data buffer (440) from a next address location in the memory circuit (230) and to store that next address in the address buffer (410). The electronic circuit further includes a multiplexer (430), a comparing circuit (420) responsive to the given address and a stored address in the address buffer (410), to operate the multiplexer (430) to pass data from the data buffer (440) or to pass data from the memory circuit (230) instead; and a mixer circuit (450) operable to put the partial write data portion into the data taken from the selected one of the data buffer (440) or memory circuit (230). Other circuits, devices, systems, processes of operation and processes of manufacture are also disclosed.
摘要翻译：一种与提供给定地址和部分写入数据部分并且还具有虚拟周期的访问电路（110）一起使用的电子电路（200）。电子电路（200）包括可在地址处访问的存储器电路（230），地址缓冲器（410），耦合到存储器电路（230）的数据缓冲器（440）和可在虚拟器件中操作的控制电路循环，从存储器电路（230）中的下一个地址位置将数据从存储器电路（230）读取到数据缓冲器（440），并将该下一个地址存储在地址缓冲器（410）中。电子电路还包括多路复用器（430），响应给定地址的比较电路（420）和地址缓冲器（410）中存储的地址，以操作多路复用器（430）以从数据缓冲器（440）传送数据）或者从存储器电路（230）传递数据; 以及混合器电路（450），其可操作以将所述部分写入数据部分放入从所述数据缓冲器（440）或存储器电路（230）中选择的数据采集的数据中。还公开了其它电路，设备，系统，操作过程和制造过程。

42. 发明申请

US20110077252A1 PYRIDYL DERIVATIVES, THEIR PREPARATION AND USE 失效
标题翻译：吡啶衍生物，其制备和使用
公开(公告)号：US20110077252A1
公开(公告)日：2011-03-31
申请号：US12672485
申请日：2008-08-06
申请人： Sanjay Kumar , Kalpana Sanjay Joshi , Vijaykumar Deore , Mandar Ramesh Bhonde , Nilambari Nilkanth Yewalkar , Amol Arun Padgaonkar , Asha Adrian Kulkarni-Almeida , Maggie Joyce Rathos , Sapna Parikh , Nilesh Madhukar Dagia
发明人： Sanjay Kumar , Kalpana Sanjay Joshi , Vijaykumar Deore , Mandar Ramesh Bhonde , Nilambari Nilkanth Yewalkar , Amol Arun Padgaonkar , Asha Adrian Kulkarni-Almeida , Maggie Joyce Rathos , Sapna Parikh , Nilesh Madhukar Dagia
IPC分类号： A61K31/501 , C07D403/04 , C07D239/34 , A61K31/505 , A61P35/00 , A61P31/14 , A61P31/18 , A61P3/10 , A61P25/28 , A61P37/00 , A61P19/02 , A61P19/10
CPC分类号： C07D213/73 , C07D213/75 , C07D213/78 , C07D401/04 , C07D407/04 , C07D413/04
摘要： The present invention relates to pyridyl derivatives capable of inhibiting phosphatidylinositol-3-kinase (PI3k), mammalian target of rapamycin (mTOR) and/or hypoxia inducible factor 1α (HIF-1α) mediated signaling. Also disclosed are processes for preparation of the pyridyl derivatives, and their use in the manufacture of pharmaceutical compositions for the treatment of clinical conditions caused by deregulation of signaling pathways selected from one or more of PI3K, mTOR and HIF-1α pathways. The pyridyl derivatives are also useful for the treatment of conditions or disorders mediated by TNF-α.
摘要翻译：本发明涉及能够抑制磷脂酰肌醇-3-激酶（PI3k），雷帕霉素哺乳动物靶（mTOR）和/或缺氧诱导因子1α（HIF-1α）介导信号传导的吡啶衍生物。还公开了制备吡啶基衍生物的方法及其在制备用于治疗由选自PI3K，mTOR和HIF-1α途径中的一种或多种的信号传导途径失调引起的临床病症的药物组合物中的用途。吡啶基衍生物也可用于治疗由TNF-α介导的病症或病症。

43. 发明申请

US20100254251A1 ARTICLES INVOLVING ENCAPSULATION OF HYGROSCOPIC MATERIALS 审中-公开
标题翻译：涉及胶体材料包埋的文章
公开(公告)号：US20100254251A1
公开(公告)日：2010-10-07
申请号：US12557720
申请日：2009-09-11
申请人： Sanjay Kumar , Giriraj Nyati , Subrata Dutta , Rajeev Jindal
发明人： Sanjay Kumar , Giriraj Nyati , Subrata Dutta , Rajeev Jindal
IPC分类号： G11B7/26
CPC分类号： G03H1/02 , B65B7/2835 , B65B25/00 , G03H2250/37 , G03H2270/22 , G03H2270/54 , G11B7/24044 , G11B7/26 , Y10T29/49826
摘要： An article involving encapsulation of one or more hygroscopic materials and manufacturing method and system thereof are provided. The article includes a first substrate, a second substrate, one or more first structures formed at a first periphery associated with the first substrate, and one or more second structures formed at a second periphery associated with the second substrate. The first structures and the second structures are engaged together mechanically to form an enclosure between the first substrate and the second substrate. The enclosure is capable of preventing exposure of a hygroscopic material encapsulated between the first substrate and the second substrate to the surrounding environment.
摘要翻译：提供一种涉及一种或多种吸湿材料的封装的制品及其制造方法和系统。所述制品包括第一衬底，第二衬底，在与所述第一衬底相关联的第一周边处形成的一个或多个第一结构以及形成在与所述第二衬底相关联的第二周边处的一个或多个第二结构。第一结构和第二结构机械地接合在一起，以在第一基板和第二基板之间形成外壳。外壳能够防止将包封在第一基板和第二基板之间的吸湿材料暴露于周围环境。

44. 发明申请

US20100203143A1 SYSTEMS AND METHODS FOR NANOMAGNETIC ACTUATION OF MOLECULAR CELL SIGNALING 有权
标题翻译：用于分子细胞信号的纳米分解的系统和方法
公开(公告)号：US20100203143A1
公开(公告)日：2010-08-12
申请号：US12595306
申请日：2008-04-09
申请人： Donald E. Ingber , Robert J. Mannix , Sanjay Kumar
发明人： Donald E. Ingber , Robert J. Mannix , Sanjay Kumar
IPC分类号： A61K9/14 , A61K39/395 , A61P35/00 , A61P9/06 , A61P5/00 , C12N13/00
CPC分类号： A61K41/0052 , A61K47/48507 , A61K47/6835 , A61N2/00 , Y10S977/904
摘要： The present invention relates to signaling mechanisms that transduce magnetic inputs into physiological cellular outputs. More particularly, the present invention relates to systems and methods for non-invasively controlling cellular signaling functions and behaviors by harnessing receptor-mediated and intracellular molecular-mediated signal transduction using nanomagnetic cellular switches.
摘要翻译：本发明涉及将磁输入转换成生理细胞输出的信号传导机制。更具体地，本发明涉及通过利用纳米磁性细胞开关利用受体介导和细胞内分子介导的信号转导来非侵入性地控制细胞信号传导功能和行为的系统和方法。

45. 发明授权

US07749369B2 Gel processing and transfer device 有权
标题翻译：凝胶加工和转移装置
公开(公告)号：US07749369B2
公开(公告)日：2010-07-06
申请号：US11265883
申请日：2006-02-17
申请人： Sanjay Kumar , Dhiraj Vyas
发明人： Sanjay Kumar , Dhiraj Vyas
IPC分类号： G01N27/447 , G01N33/559
CPC分类号： G01N27/44717 , G01N27/44704
摘要： The present invention relates to a gel processing and transfer device, useful for the processing and transferring un-damaged and intact gel with minimal handling, said device comprising at least 4 separable components namely: a base plate for holding the gels with facility to drain out solution; a retaining rim with attached side-walls, said side walls are fastened to the base plate by a fastening means; at least one “O” ring fixed to the retaining rim to give leakproof arrangement with the base plate; and a lid to cover the assembly.
摘要翻译：凝胶加工和转移装置技术领域本发明涉及一种凝胶加工和转移装置，其用于处理和转移未损坏和完整的凝胶，具有最少的处理，所述装置包括至少4个可分离的部件，即：用于保持凝胶的基板，以排出解; 具有附接侧壁的保持边缘，所述侧壁通过紧固装置固定到基板; 至少一个“O”环固定在保持边缘上，以便与基板进行防漏布置; 和盖子以覆盖组件。

46. 发明授权

US07695964B2 Compositions and methods for generating short double-stranded RNA using mutated RNAse III 失效
标题翻译：使用突变型RNA酶III产生短双链RNA的组合物和方法
公开(公告)号：US07695964B2
公开(公告)日：2010-04-13
申请号：US10586720
申请日：2005-01-21
申请人： Claude V. Maina , George Tzertzinis , Sanjay Kumar
发明人： Claude V. Maina , George Tzertzinis , Sanjay Kumar
IPC分类号： C12N5/00 , C12N5/02 , G01N33/53
CPC分类号： C12N9/22 , C12N15/111 , C12N2330/30 , C12Q1/6813 , G01N33/5023
摘要： Compositions and methods are provided for preparing an hsiRNA mixture and for silencing of gene expression in vivo. The composition relates to a mutant RnaseIII. The methods are directed to reacting a preparation of dsRNA with an effective amount of a mutant RNAse III to produce the hsiRNA mixture.
摘要翻译：提供了制备hsiRNA混合物和体内沉默基因表达的组合物和方法。该组合物涉及突变体RnaseIII。该方法旨在使dsRNA的制备物与有效量的突变型RNA酶III反应以产生hsiRNA混合物。

47. 发明授权

US07444366B2 Faster shift value calculation using modified carry-lookahead adder 失效
标题翻译：使用改进的进位前瞻加法器更快地移位值计算
公开(公告)号：US07444366B2
公开(公告)日：2008-10-28
申请号：US10853518
申请日：2004-05-26
申请人： Paul R. Thayer , Sanjay Kumar
发明人： Paul R. Thayer , Sanjay Kumar
IPC分类号： G06F7/38 , G06F7/50
CPC分类号： G06F7/5055 , G06F7/508 , H03K19/0963
摘要： Circuitry for reducing propagation delays in calculation of a value for use in a floating point multiply-accumulate operation. In the circuitry, a carry-save adder receives values of three input operands from three latches. A carry-lookahead adder receives the outputs from the carry-save adder and implements an XOR operation on a most-significant bit along with its own logic operation to produce the value for the floating point multiply-accumulate operation. Modification of the carry-lookahead adder to perform the XOR operation results in elimination of an entire stage of logic.
摘要翻译：用于减少在浮点乘法运算中使用的值的计算中的传播延迟的电路。在电路中，进位保存加法器从三个锁存器接收三个输入操作数的值。进位 - 前瞻加法器接收来自进位保存加法器的输出，并在最高有效位上执行XOR运算以及其自身的逻辑运算，以产生浮点乘法运算的值。进位前瞻加法器的修改以执行异或运算导致消除整个逻辑级。

48. 发明申请

US20080022903A1 PROCESS FOR THE PRODUCTION OF PORTLAND SLAG CEMENT USING GRANULATED BLAST FURNACE SLAG 失效
标题翻译：使用颗粒状火山灰浆生产波特兰泥浆水泥的方法
公开(公告)号：US20080022903A1
公开(公告)日：2008-01-31
申请号：US11491916
申请日：2006-07-25
申请人： Rakesh Kumar , Sanjay Kumar , Amitava Bandopadhaya , Surya Pratap Mehrotra
发明人： Rakesh Kumar , Sanjay Kumar , Amitava Bandopadhaya , Surya Pratap Mehrotra
IPC分类号： C04B7/19 , C04B7/14 , C04B2/10
CPC分类号： C04B28/04 , C04B18/141 , Y02W30/94 , C04B20/008 , C04B20/026
摘要： Accordingly, the present invention provides an improved process for the production of Portland slag cement using granulated blast furnace slag, which comprises: (viii) forming of cement clinker by known process, (ix) ball-milling of cement clinker for a period ranging between 30-60 minutes in dry condition, (x) reducing size of granulated blast furnace slag by any process to obtain the size in the range between 210 to 100 μm for using as feed for attrition mill, (xi) wet milling of granulated blast furnace slag for a period ranging between 5-15 minutes in an attrition mill using granulated blast furnace slag to water ratio in the range of 1:1 to 1:2 and granulated blast furnace slag to grinding bail ratio in the range of 1:5 to 1:15, (xii) removing water from the slurry obtained after attrition milling by known process, (xiii) drying of the obtained slurry by known process, (xiv) mixing intimately of: attrition milled slag obtain in step (vi) in the range of: 50 to 95% by weight ball-milled clinker obtain in step (ii) in the range of: 05 to 45% by weight gypsum in the range of: 01 to 05% by weight for a period in the range of 15 to 30 minutes.
摘要翻译：因此，本发明提供了一种使用造粒高炉矿渣生产波特兰矿渣水泥的改进方法，其包括：（viii）通过已知方法形成水泥熟料，（ix）水泥熟料的球磨，时间范围在干燥条件下30-60分钟，（x）通过任何工艺减少造粒高炉矿渣的尺寸，以获得用于磨粉机进料的210至100um之间的尺寸，（xi）造粒高炉的湿磨在磨粉机中使用造粒高炉矿渣与水的比例在1：1至1：2范围内的炉渣在5-15分钟之间，并将造粒高炉矿渣与1：5至（xii）通过已知方法磨碎后得到的浆料中的水，（xiii）通过已知方法干燥所获得的浆料，（xiv）密切混合：步骤（vi）中获得的磨碎的炉渣范围：50〜95重量％研磨熟料在步骤（ii）中获得的范围为：05至45重量％的石膏，其范围为：01至05重量％，范围为15至30分钟。

49. 发明申请

US20060135757A1 DNA sequence in plant Caragana jubata with freeze tolerance 审中-公开
标题翻译：植物Caragana jubata中具有耐冻性的DNA序列
公开(公告)号：US20060135757A1
公开(公告)日：2006-06-22
申请号：US11304613
申请日：2005-12-16
申请人： Sanjay Kumar , Rajesh Gupta , Paramvir Ahuja
发明人： Sanjay Kumar , Rajesh Gupta , Paramvir Ahuja
IPC分类号： C07H21/04
CPC分类号： C07K14/415 , C12Q1/6895 , C12Q2600/158
摘要： An isolated DNA sequence set forth in SEQ ID NO: 32, which is differentially expressed in apical buds of plant Caragana jubata (Pall.) under freezing conditions, is disclosed.
摘要翻译：公开了在冷冻条件下在植物Caragana jubata（Pall。）的顶芽中差异表达的SEQ ID NO：32所示的分离的DNA序列。

50. 发明申请

US20060111848A1 Identification and use of cofactor independent phosphoglycerate mutase as a drug target for pathogenic organisms and treatment of the same 审中-公开
标题翻译：鉴定和使用辅因子独立磷酸甘油酸变位酶作为致病生物体的药物靶点及其治疗
公开(公告)号：US20060111848A1
公开(公告)日：2006-05-25
申请号：US11316521
申请日：2005-12-22
申请人： Clotilde Carlow , Yinhua Zhang , Jeremy Foster , Sanjay Kumar
发明人： Clotilde Carlow , Yinhua Zhang , Jeremy Foster , Sanjay Kumar
IPC分类号： G06F19/00
CPC分类号： C12N9/90 , C12Q1/18 , G16B10/00 , G16B20/00 , G16B30/00
摘要： Present embodiments of the invention describe computational methods for performing a systematic, genome-wide search for novel drug targets in pathogenic organisms for example, the human filarial parasites. Cofactor independent phosphoglycerate mutase (iPGM) was identified by this search as a candidate target for identifying therapeutic agents for use in treating animal or plant subjects infected with parasitic nematodes, microbial pathogens including microsporidia, fungi etc. A consensus amino acid or nucleotide sequence that characterizes iPGM is further provided.
摘要翻译：本发明的现有实施方案描述了用于在致病生物体（例如人类丝虫）中进行系统的全基因组搜索新型药物靶标的计算方法。通过该搜索将辅因子独立的磷酸甘油酸变位酶（iPGM）鉴定为用于鉴定用于治疗感染寄生线虫，包括微孢子虫，真菌等的微生物病原体的动物或植物受试者的治疗剂的候选靶标。表征的共有氨基酸或核苷酸序列还提供iPGM。

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