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    • 42. 发明申请
    • MICROBIOCIDAL HETEROCYCLES
    • 微生物杂交
    • US20120142698A1
    • 2012-06-07
    • US13390023
    • 2010-08-06
    • Sarah Sulzer-MosseClemens LamberthLaura QuarantaMathias Stephan Respondek
    • Sarah Sulzer-MosseClemens LamberthLaura QuarantaMathias Stephan Respondek
    • A01N43/60C07D207/09C07D207/48C07D401/14C07D401/04A01P3/00C07D403/04A01N43/56A01N43/36A01N43/40A01N43/54C07D403/06C07D403/14
    • C07D401/14C07D231/12C07D401/04C07D401/06C07D401/12
    • The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R10R11)—C(═O)—, x-C(R12R13)—C(═S)—, x-O—C(═O)—, x-O—C(═S)—, x-N(R14)—C(═O)—, x-N(R15)—C(═S)—, x-C(R16R17)—SO2— or X—N═C(R30)—, in each case x indicates the bond that is connected to R1; T is CR18 or N; Y1, Y2, Y3, and Y4 are independently CR19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R1 is phenyl, pyridyl, imidazolyl, or pyrazolyl; wherein the phenyl, pyridyl, imidazolyl and pyrazolyl are each optionally substituted by 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18, R19 and R30 each independently are hydrogen, halogen, cyano, C1-C4alkyl, or C1-C4haloalkyl; R8, R14 and R15 each independently are hydrogen or C1-C4alkyl; and R9 is phenyl, benzyl or group (a): wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
    • 本发明涉及具有杀微生物活性,特别是杀真菌活性的式I的杂环化合物以及使用式(I)化合物来控制微生物的方法:其中A是xC(R10R11)-C(= O) - ,xC(R12R13)-C(= S) - ,xO-C(= O) - ,xO-C(= S) - ,xN(R14)-C(= O) - ,xN(R15)-C (X)(R 16 R 17)-SO 2 - 或X-N = C(R 30) - ,在各种情况下,x表示与R1连接的键; T为CR18或N; Y1,Y2,Y3和Y4独立地为CR19或N; Q是O或S; n为1或2; p为1或2,条件是当n为2时,p为1. R1为苯基,吡啶基,咪唑基或吡唑基; 其中苯基,吡啶基,咪唑基和吡唑基各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和氨基的取代基取代; R2,R3,R4,R5,R6,R7,R10,R11,R12,R13,R16,R17,R18,R19和R30各自独立地为氢,卤素,氰基,C1-C4烷基或C1-C4卤代烷基; R8,R14和R15各自独立地为氢或C1-C4烷基; 并且R 9为苯基,苄基或基团(a):其中苯基,苄基和基团(a)各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和 氨基; 或其盐或N-氧化物。