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41. 发明授权

US08262695B2 Structures for permanent occlusion of a hollow anatomical structure 有权
标题翻译：中空解剖结构永久闭塞的结构
公开(公告)号：US08262695B2
公开(公告)日：2012-09-11
申请号：US11339978
申请日：2006-01-25
申请人： Halil I. Karabey , Anna G. Prestezog , Michael S. Mirizzi , Brian Farley , John W. Rodriguez , Russell B. Thompson
发明人： Halil I. Karabey , Anna G. Prestezog , Michael S. Mirizzi , Brian Farley , John W. Rodriguez , Russell B. Thompson
IPC分类号： A61B17/08
CPC分类号： A61B17/12186 , A61B17/06 , A61B17/12022 , A61B17/12031 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12181 , A61B17/1219 , A61B17/122 , A61B2017/00898 , A61B2017/0474 , A61B2017/06176 , A61B2017/1205
摘要： An apparatus for treating a hollow anatomical structure comprises an implant sized for insertion into a hollow anatomical structure. The implant comprises a plurality of loose, bulked fibers. The fibers are formed from one or more bioabsorbable materials.
摘要翻译：用于治疗中空解剖结构的装置包括尺寸适于插入中空解剖结构中的植入物。植入物包括多个松散的膨松纤维。纤维由一种或多种生物可吸收材料形成。

42. 发明申请

US20110144642A1 METHOD AND APPARATUS FOR COAGULATING AND/OR CONSTRICTING HOLLOW ANATOMICAL STRUCTURES 有权
标题翻译：用于凝结和/或约束中空解剖结构的方法和装置
公开(公告)号：US20110144642A1
公开(公告)日：2011-06-16
申请号：US12917329
申请日：2010-11-01
申请人： Michael S. Mirizzi , Christopher Scott Jones , Arthur W. Zikorus
发明人： Michael S. Mirizzi , Christopher Scott Jones , Arthur W. Zikorus
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B18/00 , A61B2017/00084 , A61B2017/22051 , A61B2018/00095 , A61F7/123 , A61F2007/126 , A61M25/00 , A61M25/1011 , A61M2025/1072 , A61M2025/1086
摘要： An energy delivering probe is used for thermally coagulating and/or constricting hollow anatomical structures (HAS) including, but not limited to, blood vessels such as perforator veins. The probe includes a shaft and at least two electrodes where at least one of the electrodes has a generally spherical or toroidal geometry.
摘要翻译：能量输送探针用于热凝固和/或收缩中空解剖结构（HAS），包括但不限于血管如穿孔静脉。探针包括轴和至少两个电极，其中至少一个电极具有大致球形或环形几何形状。

43. 发明申请

US20090159088A1 METHOD FOR PERMANENT OCCLUSION OF FALLOPIAN TUBE 有权
标题翻译：方法对永久性管腔的破坏
公开(公告)号：US20090159088A1
公开(公告)日：2009-06-25
申请号：US12340265
申请日：2008-12-19
申请人： Halil I. Karabey , Anna G. Prestezog , Michael S. Mirizzi , John W. Rodriguez
发明人： Halil I. Karabey , Anna G. Prestezog , Michael S. Mirizzi , John W. Rodriguez
IPC分类号： A61F6/22
CPC分类号： A61B17/12186 , A61B17/06 , A61B17/12022 , A61B17/12031 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/12159 , A61B17/12172 , A61B17/12181 , A61B17/1219 , A61B17/122 , A61B2017/00898 , A61B2017/0474 , A61B2017/06176 , A61B2017/1205
摘要： Disclosed is a method and apparatus of contraception. The apparatus can include an implant sized for insertion into a fallopian tube. The implant can comprise a plurality of loose, bulked fibers. The fibers can be formed from one or more bioabsorbable materials, for example, the method can include inserting the implant into a fallopian tube and occluding the fallopian tube with the implant.
摘要翻译：公开了一种避孕方法和装置。该装置可以包括尺寸适于插入输卵管的植入物。植入物可以包括多个松散的，膨胀的纤维。纤维可以由一种或多种生物可吸收材料形成，例如，该方法可以包括将植入物插入输卵管并用植入物闭塞输卵管。

44. 发明申请

US20080292255A1 SYSTEMS AND METHODS FOR TREATING HOLLOW ANATOMICAL STRUCTURES 有权
标题翻译：用于治疗中枢解剖结构的系统和方法
公开(公告)号：US20080292255A1
公开(公告)日：2008-11-27
申请号：US12110169
申请日：2008-04-25
申请人： Walter J. Stevens , Stephen W. Lee , Michael S. Mirizzi , Hoa D. Nguyen
发明人： Walter J. Stevens , Stephen W. Lee , Michael S. Mirizzi , Hoa D. Nguyen
IPC分类号： G02B6/06
CPC分类号： G02B6/06 , A61B18/24 , A61B2017/22001 , A61B2018/00029 , A61B2018/2261 , A61M29/02
摘要： An apparatus for treating a hollow anatomical structure can include a light delivery device. The light delivery device comprises an optical fiber that is located in a lumen of a shaft suitable for insertion into the hollow anatomical structure and has a fiber tip located proximal of a distal end of the shaft during treatment of the hollow anatomical structure. The apparatus can further include a liquid source for providing a liquid flow over the optical fiber at a predetermined liquid flow rate.
摘要翻译：用于治疗中空解剖结构的装置可以包括光输送装置。光输送装置包括光纤，其位于适于插入中空解剖结构的轴的内腔中，并且在处理中空解剖结构期间具有位于轴的远端附近的纤维末端。该装置还可以包括用于以预定液体流速在光纤上提供液体流的液体源。

45. 发明授权

US06290710B1 Embolic protection device 有权
标题翻译：栓塞保护装置
公开(公告)号：US06290710B1
公开(公告)日：2001-09-18
申请号：US09474557
申请日：1999-12-29
申请人： Brett W. Cryer , Michael S. Mirizzi
发明人： Brett W. Cryer , Michael S. Mirizzi
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0078
摘要： A self-expanding filtration element is fitted to the distal end of a catheter while a sheath for constraining such element to a reduced diameter is mechanically manipulatable from the proximal end of the device. The entire device is maneuvered into position over a guide wire and deployed prior to treatment of the body lumen at an upstream location. After completion of the treatment procedure, the filtration element is collapsed and constrained within the sheath to retain any embolic material that has been captured and allow it to be safely removed from the vasculature. The device may be combined with a primary treatment modality and its low profile allows the constrained filtration element to be removed through a deployed stent.
摘要翻译：自扩张过滤元件装配到导管的远端，而用于将这种元件限制到直径减小的护套可从装置的近端机械地操纵。整个装置被操纵在导丝上的位置并且在上游位置处理体腔前部署。在完成治疗过程之后，过滤元件被塌缩并且被限制在护套内以保持已经被捕获的任何栓塞材料，并允许其从脉管系统中被安全地移除。该装置可以与主要处理方式组合，并且其低轮廓允许经限制的过滤元件通过展开的支架移除。

46. 发明授权

US06240615B1 Method and apparatus for uniformly crimping a stent onto a catheter 失效
标题翻译：将支架均匀地压接在导管上的方法和装置
公开(公告)号：US06240615B1
公开(公告)日：2001-06-05
申请号：US09409198
申请日：1999-09-30
申请人： Richard M. Kimes , Michael S. Mirizzi
发明人： Richard M. Kimes , Michael S. Mirizzi
IPC分类号： B23P1100
CPC分类号： A61F2/958 , A61F2002/9522 , Y10T29/49927 , Y10T29/53952 , Y10T29/53987 , Y10T29/53996
摘要： A stent crimping tool for firmly and uniformly crimping a stent onto a balloon catheter is constructed from a crimping section holding the stent and the balloon catheter therein, wherein the crimping is actuated by a shaft having an input end and an output end, engaging the crimping section at the output end. The shaft has a detent formed into the input end. A gripping member has an internal cavity to receive the input end, and includes a hole proximate to the shaft, wherein a ball bearing and a compression spring are located within the hole to bias the ball bearing toward the shaft and to engage the detent. When a torque is applied to the gripping member, it is transmitted through the ball bearing to the shaft; if the torque exceeds a predetermined magnitude, it overcomes the force of the spring on the ball bearing causing the bearing to slide out of the detent thereby disconnecting the applied torque from the shaft. The crimping section can be a rubber tube having a lumen holding the stent and catheter. When the shaft compresses the rubber tube as it advances, the lumen collapses and crimps the stent onto the catheter. In another embodiment, the crimping section is a coiled filament suspended at both ends and having an axial space holding the stent and catheter. Rotating the shaft twists the filament which in turn constricts and crimps the stent onto the catheter.
摘要翻译：用于将支架牢固且均匀地压接在球囊导管上的支架压接工具由将支架和气囊导管保持在其中的压接部分构成，其中，压接由具有输入端和输出端的轴致动，在输出端。轴具有形成输入端的制动器。夹持构件具有内部空腔以容纳输入端，并且包括靠近轴的孔，其中球轴承和压缩弹簧位于孔内以将球轴承朝向轴偏压并接合止动件。当扭矩施加到夹持构件时，其通过滚珠轴承传递到轴; 如果扭矩超过预定的大小，则它克服了滚珠轴承上的弹簧的力，导致轴承滑出制动器，从而将施加的扭矩与轴断开。卷曲部可以是具有保持支架和导管的内腔的橡胶管。当轴在橡胶管前进时压缩橡胶管时，管腔将支架折叠并卷曲到导管上。在另一个实施例中，卷曲部分是悬挂在两端并具有保持支架和导管的轴向空间的卷绕细丝。旋转轴扭转细丝，其又将支架收缩并卷曲到导管上。

47. 发明授权

US6108886A Method and apparatus for uniformly crimping a stent onto a catheter 失效
标题翻译：用于将支架均匀地压接到导管上的装置
公开(公告)号：US6108886A
公开(公告)日：2000-08-29
申请号：US340967
申请日：1999-06-28
申请人： Richard M. Kimes , Michael S. Mirizzi
发明人： Richard M. Kimes , Michael S. Mirizzi
IPC分类号： A61F2/06 , A61F2/84 , A61M29/00
CPC分类号： A61F2/958 , A61F2002/9522 , Y10T29/49927 , Y10T29/53952 , Y10T29/53987 , Y10T29/53996
摘要： A stent crimping tool for firmly and uniformly crimping a stent onto a balloon catheter is constructed from a crimping section holding the stent and the balloon catheter therein, wherein the crimping is actuated by a shaft having an input end and an output end, engaging the crimping section at the output end. The shaft has a detent formed into the input end. A gripping member has an internal cavity to receive the input end, and includes a hole proximate to the shaft, wherein a ball bearing and a compression spring are located within the hole to bias the ball bearing toward the shaft and to engage the detent. When a torque is applied to the gripping member, it is transmitted through the ball bearing to the shaft; if the torque exceeds a predetermined magnitude, it overcomes the force of the spring on the ball bearing causing the bearing to slide out of the detent thereby disconnecting the applied torque from the shaft. The crimping section can be a rubber tube having a lumen holding the stent and catheter. When the shaft compresses the rubber tube as it advances, the lumen collapses and crimps the stent onto the catheter. In another embodiment, the crimping section is a coiled filament suspended at both ends and having an axial space holding the stent and catheter. Rotating the shaft twists the filament which in turn constricts and crimps the stent onto the catheter.
摘要翻译：用于将支架牢固且均匀地压接在球囊导管上的支架压接工具由将支架和气囊导管保持在其中的压接部分构成，其中，压接由具有输入端和输出端的轴致动，在输出端。轴具有形成输入端的制动器。夹持构件具有内部空腔以容纳输入端，并且包括靠近轴的孔，其中球轴承和压缩弹簧位于孔内以将球轴承朝向轴偏压并接合止动件。当扭矩施加到夹持构件时，其通过滚珠轴承传递到轴; 如果扭矩超过预定的大小，则它克服了滚珠轴承上的弹簧的力，导致轴承滑出制动器，从而将施加的扭矩与轴断开。卷曲部可以是具有保持支架和导管的内腔的橡胶管。当轴在橡胶管前进时压缩橡胶管时，管腔将支架折叠并卷曲到导管上。在另一个实施例中，卷曲部分是悬挂在两端并具有保持支架和导管的轴向空间的卷绕细丝。旋转轴扭转细丝，其又将支架收缩并卷曲到导管上。

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