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41. 发明申请

US20120059396A1 Device For Deploying A Fastener For Use In A Gastric Volume Reduction Procedure 审中-公开
标题翻译：用于部署紧固件的装置用于胃体积减少程序
公开(公告)号：US20120059396A1
公开(公告)日：2012-03-08
申请号：US13294241
申请日：2011-11-11
申请人： Jason L. Harris , Michael J. Stokes , Mark S. Zeiner
发明人： Jason L. Harris , Michael J. Stokes , Mark S. Zeiner
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0483 , A61B17/0487 , A61B17/06114 , A61B17/06166 , A61B17/3462 , A61B17/3478 , A61B90/90 , A61B2017/00278 , A61B2017/00818 , A61B2017/00867 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0474 , A61B2017/0475 , A61B2017/0496 , A61B2017/06052 , A61B2017/306 , A61F5/0079 , A61F5/0086 , A61M13/003
摘要： A method and device for manipulating gastric tissue about a greater curvature of a stomach. The method includes the steps of creating at least one incision to gain access to the peritoneal cavity, and dissecting at least a portion of the greater omentum. Then the method includes accessing the exterior of the gastric tissue through the incision and folding at least a portion of the greater curvature of the stomach. The fold is constructed having serosa to serosa contact substantially along its entire length. The method further involves securing the fold with a flexible member wherein the flexible member comprises at least one tissue securing feature.
摘要翻译：一种用于围绕较大曲率的胃操作胃组织的方法和装置。该方法包括以下步骤：产生至少一个切口以进入腹膜腔，以及解剖大网膜的至少一部分。然后，该方法包括通过切口进入胃组织的外部并折叠胃的较大曲率的至少一部分。折叠被构造成具有大致沿着其整个长度的浆膜到浆膜的接触。该方法还包括用柔性构件固定折叠物，其中柔性构件包括至少一个组织固定特征。

42. 发明申请

US20110295180A1 INTESTINAL BRAKE INDUCING INTRALUMINAL THERAPEUTIC SUBSTANCE ELUTING DEVICES AND METHODS 有权
标题翻译： INTESTINAL BRAKE INDING IN INTRALUMINAL THERAPEUTIC THEAPEUTIC TYSTURE ELDTING ELTERTING DEVICES AND METHODS
公开(公告)号：US20110295180A1
公开(公告)日：2011-12-01
申请号：US13105029
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F5/0079 , A61F2002/045
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要翻译：方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。在一个实施方案中，可植入系统包括将治疗物质递送到患者胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。

43. 发明申请

US20110060308A1 METHODS AND IMPLANTS FOR INDUCING SATIETY IN THE TREATMENT OF OBESITY 审中-公开
标题翻译：诱导治疗肥胖的方法和植入物
公开(公告)号：US20110060308A1
公开(公告)日：2011-03-10
申请号：US12554005
申请日：2009-09-04
申请人： Michael J. Stokes , Jason L. Harris , Mark S. Zeiner , Elliott J. Fegelman , William B. Weisenburgh, II , Christopher J. Hess
发明人： Michael J. Stokes , Jason L. Harris , Mark S. Zeiner , Elliott J. Fegelman , William B. Weisenburgh, II , Christopher J. Hess
IPC分类号： A61M31/00
CPC分类号： A61F5/0069 , A61B17/3478 , A61B2017/00818 , A61B2017/00867 , A61B2050/3006 , A61B2050/3007 , A61F5/0013
摘要： A method for inducing satiety using the steps of inserting an elongated device into a patient through a natural orifice and into a stomach of the patient, placing a distal end of the elongated device adjacent a treatment site within the stomach, and delivering at least one space occupying member through the elongated device adjacent the treatment site and implanting the at least one space occupying member between the submucosal and muscularis layers at the target site.
摘要翻译：一种诱导饱腹感的方法，其特征在于使用将细长装置通过天然孔口插入患者胃部的步骤，将细长装置的远端邻近治疗部位放置在胃内，并且将至少一个空间通过邻近治疗部位的细长装置占据构件，并且在目标部位在植入粘膜下层和肌层之间的至少一个空间占据构件。

44. 发明申请

US20100187285A1 SURGICAL STAPLER FOR APPLYING A LARGE STAPLE THOUGH A SMALL DELIVERY PORT AND A METHOD OF USING THE STAPLER TO SECURE A TISSUE FOLD 审中-公开
标题翻译：用于通过小型输送口应用大口袋的外科手术台和使用贴标机来保护组织结构的方法
公开(公告)号：US20100187285A1
公开(公告)日：2010-07-29
申请号：US12359354
申请日：2009-01-26
申请人： Jason L. Harris , Lawrence Craininch , Michael J. Stokes
发明人： Jason L. Harris , Lawrence Craininch , Michael J. Stokes
IPC分类号： A61B17/115 , A61B17/064
CPC分类号： A61B17/064 , A61B17/00234 , A61B17/0684 , A61B17/29 , A61B2017/00818 , A61B2017/07264
摘要： A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains a plurality of surgical fasteners. The surgical fasteners have a base, and two legs extending away from the base, wherein the legs have distal end segments. The fastener has a first shape wherein the distal end segments bend towards each other so that they are adjacent and form the fastener into a first loop. The fastener has a second shape wherein the distal end segments are spaced apart from each other along substantially an entire length thereof. The fastener also has a third shape wherein the distal end segments bend towards each other in so that they are adjacent and form the fastener into a second loop wherein the second loop having a width greater than a width of the first loop. The applier includes a means for forming the fastener into the second and third shapes.
摘要翻译：具有手柄和从手柄延伸的紧固件外壳的手术紧固件施加器。外壳包含多个手术紧固件。手术紧固件具有基部和两个远离基部延伸的腿，其中腿具有远端段。紧固件具有第一形状，其中远端段彼此弯曲，使得它们相邻并且将紧固件形成第一回路。紧固件具有第二形状，其中远端段在其大致整个长度上彼此间隔开。紧固件还具有第三形状，其中远端段彼此弯曲成使得它们相邻并且将紧固件形成第二环，其中第二环具有大于第一环的宽度的宽度。施加器包括用于将紧固件形成第二和第三形状的装置。

45. 发明申请

US20090275977A1 TISSUE CONVEYOR FOR USE IN GASTRIC REDUCTION SURGERY AND ASSOCIATED METHOD FOR USE 有权
标题翻译：用于胃肠减容手术的组织输送机及相关使用方法
公开(公告)号：US20090275977A1
公开(公告)日：2009-11-05
申请号：US12113765
申请日：2008-05-01
申请人： Mark S. Zeiner , Michael J. Stokes , Jason L. Harris
发明人： Mark S. Zeiner , Michael J. Stokes , Jason L. Harris
IPC分类号： A61B17/28
CPC分类号： A61F5/0086 , A61B17/00491 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/08 , A61B17/1114 , A61B2017/00818 , A61B2017/0409 , A61B2017/0417 , A61B2017/06052 , A61B2017/081 , A61B2017/2926
摘要： A tissue conveyor includes a conveyor body having a proximal end and a distal end. The proximal end includes a handle allowing for operator control of an end effector located at the distal end. The end effector includes a grasper assembly composed of a first jaw bar and a second jaw bar connected by a support base to define a cavity into which tissue is drawn. A first conveyor member is positioned upon the first jaw bar for movement along an internal surface of the first jaw bar and a second conveyor member is positioned upon the second jaw bar for movement along an internal surface of the second jaw bar. The method for creating a tissue fold includes positioning a tissue conveyor adjacent tissue, pushing the respective first jaw bar and the second jaw bar into the tissue in the area where a fold is desired, and pulling the first conveyor member and the second conveyor member proximally to draw the first and second conveyor members and tissue into a cavity defined by the first jaw bar and the second jaw bar to create a tissue fold.
摘要翻译：纸巾输送机包括具有近端和远端的输送机主体。近端包括允许操作者控制位于远端的末端执行器的手柄。端部执行器包括由第一钳口杆和由支撑基座连接的第二钳口条组成的抓紧器组件，以限定抽出组织的空腔。第一传送器构件定位在第一钳口杆上，用于沿着第一钳口杆的内表面移动，并且第二传送构件定位在第二钳口杆上，用于沿着第二钳口杆的内表面移动。用于产生组织折叠的方法包括将组织输送器定位成邻近组织，将相应的第一钳口条和第二钳口杆推向需要折叠的区域中的组织中，并且将第一传送构件和第二传送构件向近侧拉以将第一和第二传送器构件和组织拉入由第一颚板和第二颚条限定的空腔中以产生组织折叠。

46. 发明申请

US20090275964A1 METHOD OF ROLLING STOMACH TISSUE SO AS TO MAXIMIZE THE CONTACT SURFACE AREA OF A FOLD 审中-公开
标题翻译：滚动组织的方法，以便最大限度地减少接触面的面积
公开(公告)号：US20090275964A1
公开(公告)日：2009-11-05
申请号：US12113773
申请日：2008-05-01
申请人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Daniel E. Alesi , Mark S. Ortiz , Thomas E. Albrecht , James T. Spivey , Lawrence Crainich
发明人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Daniel E. Alesi , Mark S. Ortiz , Thomas E. Albrecht , James T. Spivey , Lawrence Crainich
IPC分类号： A61B17/12 , A61B17/34
CPC分类号： A61B17/00234 , A61B2017/00827 , A61B2017/00867 , A61B2017/0649 , A61B2017/081 , A61B2017/2926 , A61F5/0086
摘要： A rolling instrument for rolling the outside surface of the stomach for reducing stomach volume in bariatric surgery includes an elongated tubular body that is sufficiently flexible to allow for access to the outside surface. The tubular body includes a proximal end and a distal end. The proximal end is shaped and dimensioned for use by the medical practitioner performing the medical procedure and includes a handle for manipulation of the rolling instrument. The distal end of the tubular body includes a mechanism allowing for gripping of the stomach in a manner permitting rolling thereof. A coiled retainer shaped and dimensioned is provided for application to the rolled portion of the stomach in a manner holding the rolled portion of the stomach in its rolled configuration. The coiled retainer includes a helically coiled body having a first end and a second end, the first end is pointed such that it may puncture tissue as the coiled body is rotated during its application to the stomach.
摘要翻译：用于在减肥手术中滚动用于减少胃体积的胃的外表面的滚动仪器包括具有足够柔性以允许进入外表面的细长管状体。管状体包括近端和远端。近端的形状和尺寸被医生执行医疗程序所使用，并且包括用于操纵滚动仪器的手柄。管状体的远端包括允许以允许其滚动的方式夹持胃的机构。提供成形和尺寸的盘形保持器，以使其处于卷成形状的胃的卷绕部分的方式施加到胃的卷绕部分。卷绕的保持器包括具有第一端和第二端的螺旋状卷绕体，第一端是尖的，使得当线圈体在其施加到胃部期间旋转时可能刺穿组织。

47. 发明申请

US20090272783A1 FASTENER AND FASTENER APPLIER HAVING SELECTIVE SUTURE ATTACHMENT 有权
标题翻译：具有选择性附件的紧固件和紧固件应用
公开(公告)号：US20090272783A1
公开(公告)日：2009-11-05
申请号：US12113644
申请日：2008-05-01
申请人： Lawrence Crainich , Mark S. Zeiner , Michael J. Stokes , Jason L. Harris
发明人： Lawrence Crainich , Mark S. Zeiner , Michael J. Stokes , Jason L. Harris
IPC分类号： A61B17/068
CPC分类号： A61B17/0684 , A61B17/0401 , A61B17/0644 , A61B2017/0409 , A61B2017/0488
摘要： A surgical stapling device for deploying staples connected with suture to tissue includes a handle having a staple actuator mechanism, a tubular support shaft having a longitudinal axis and extending from the handle, and a staple cartridge mounted on the support shaft and connected to the staple actuator mechanism for applying one or more staples to the tissue. The cartridge has a cartridge housing adapted to receive a plurality of staples in a row for longitudinal movement therethrough and an anvil mounted on the housing. The cartridge further includes a mechanism for advancing the forwardmost staple in the row into engagement with the anvil, and a suture guide supporting a length of suture that extends in a loop for attachment to the staples as they are secured to the tissue.
摘要翻译：一种用于将与缝合线连接的组织部署到外科缝合装置的手术装置包括具有缝钉致动器机构的手柄，具有纵向轴线并从手柄延伸的管状支撑轴，以及安装在支撑轴上并连接到钉子致动器用于将一个或多个钉钉施加到组织的机构。该盒具有一个盒壳体，其适于容纳一行中的多个钉，用于纵向运动，并且安装在壳体上的砧座。所述筒还包括用于将所述排中的最前面的钉向前推进与所述砧座接合的机构，以及缝合线引导件，所述缝合线引导件支撑一定长度的缝合线，所述缝线引导件在环路中延伸，以便在固定到所述组织上时与所述缝钉连接。

48. 发明申请

US20090118762A1 Disposable cartridge for use in a gastric volume reduction procedure 审中-公开
标题翻译：用于胃体积减少手术的一次性药筒
公开(公告)号：US20090118762A1
公开(公告)日：2009-05-07
申请号：US11930291
申请日：2007-10-31
申请人： Lawrence Crainch , Mark S. Zeiner , Michael J. Stokes , Daniel Alesi , Jason L. Harris
发明人： Lawrence Crainch , Mark S. Zeiner , Michael J. Stokes , Daniel Alesi , Jason L. Harris
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/0467 , A61B2017/00818 , A61B2017/0409 , A61B2017/0416 , A61B2017/0417
摘要： A cartridge containing a fastener, wherein the cartridge releasably connected to a fastener deploying device. The cartridge has a housing which houses at least one tissue penetrating member. The penetrating member at least partially houses a fastener. The fastener has at least two rigid anchors connected together by a flaccid member. The cartridge further includes a means for removably attaching the cartridge to a deployment device.
摘要翻译：一种包含紧固件的盒，其中盒可释放地连接到紧固件展开装置。该盒具有容纳至少一个组织穿透构件的壳体。穿透构件至少部分地容纳紧固件。紧固件具有至少两个由松弛部件连接在一起的刚性锚固件。墨盒还包括用于将墨盒可拆卸地附接到展开装置的装置。

49. 发明授权

US09084599B2 Surgical stapling instrument for applying a large staple through a small delivery port and a method of using the surgical stapler to secure a tissue fold 有权
标题翻译：用于通过小的输送口施加大的钉的外科缝合器械以及使用外科缝合器固定组织折叠的方法
公开(公告)号：US09084599B2
公开(公告)日：2015-07-21
申请号：US12113829
申请日：2008-05-01
申请人： Mark S. Zeiner , Michael J. Stokes , Jason L. Harris , Daniel E. Alesi , Lawrence Crainich
发明人： Mark S. Zeiner , Michael J. Stokes , Jason L. Harris , Daniel E. Alesi , Lawrence Crainich
IPC分类号： A61B17/068 , A61B17/00 , A61B17/64 , A61B17/29
CPC分类号： A61B17/068 , A61B17/00234 , A61B17/0684 , A61B17/6425 , A61B2017/0034 , A61B2017/00818 , A61B2017/2929
摘要： A low-profile surgical stapler enables a large-sized staple to be delivered into a body cavity through a small opening or port. The surgical stapler includes a handle having a trigger movably coupled to the handle. The surgical stapler also includes an elongated, tubular shaft extends distally from the handle. The tubular shaft includes a proximal end secured to the handle and a distal end in which a deployment opening is formed. A staple deploying assembly is disposed within an interior of the shaft for discharging staples from the deployment opening at the distal end of the shaft, the staple deploying assembly supporting a staple such that a longitudinal axis of the staple is aligned with a longitudinal axis of the shaft. The deployment opening is shaped and dimensioned to permit the deployment of the staples from within the shaft, out of the deployment opening and into adjacent tissue.
摘要翻译：低调外科缝合器使得大尺寸的钉可以通过小的开口或端口输送到体腔中。手术吻合器包括具有可移动地联接到手柄的触发器的手柄。手术吻合器还包括从手柄向远侧延伸的细长管状轴。管状轴包括固定到手柄的近端和形成有展开开口的远端。缝钉展开组件设置在轴的内部，用于在轴的远端处从排出口排出订书钉，所述订书钉展开组件支撑订书钉，使得订书钉的纵向轴线与轴。展开口的形状和尺寸被设计成允许订书针从轴内部伸出展开开口并进入邻近的组织。

50. 发明授权

US08636751B2 Methods and devices for the rerouting of chyme to induce intestinal brake 有权
标题翻译：用于重新路由食糜诱导肠内制动的方法和装置
公开(公告)号：US08636751B2
公开(公告)日：2014-01-28
申请号：US13104192
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , Mario Gutierrez , Prasanna Malaviya , Amy L. Marcotte , Jeffrey D. Messerly , Anthony Nguyen , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , Lauren S. Weaner , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , Mark S. Zeiner
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , Mario Gutierrez , Prasanna Malaviya , Amy L. Marcotte , Jeffrey D. Messerly , Anthony Nguyen , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , Lauren S. Weaner , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , Mark S. Zeiner
IPC分类号： A61B17/10
CPC分类号： A61B17/00234 , A61B5/0031 , A61B5/036 , A61B5/073 , A61B5/076 , A61B5/1107 , A61B5/14532 , A61B5/14539 , A61B5/42 , A61B17/0469 , A61B17/1114 , A61B2017/00876 , A61B2017/1117 , A61B2017/1139 , A61B2560/0219 , A61F2/04 , A61F5/0013 , A61F2002/045
摘要： Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may include one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.
摘要翻译：方法和装置重新路由食糜诱导肠道制动，以提高减肥手术的有效性和改善共病分解。肠道被操纵以提供用于食糜行进到回肠的缩短路径。用于诱导肠内制动器的这些重新路由食糜的方法和装置可以包括外科手术，植入装置或具有改进的外科手术的植入物的组合中的一种或多种。

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