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41. 发明申请

WO2020251656A1 PREMATURE VENTRICULAR CONTRACTION (PVC) DETECTION 审中-公开
公开(公告)号：WO2020251656A1
公开(公告)日：2020-12-17
申请号：PCT/US2020/028054
申请日：2020-04-14
申请人： MEDTRONIC, INC.
发明人： RAJAGOPAL, Gautham , HUDZIAK, Michael, L. , SARKAR, Shantanu , TOERING, Gary , REILAND, Jerry, D. , CHAO, Yuying , CHEN, Stephanie
IPC分类号： A61N1/37 , A61N1/362 , A61N1/365 , A61B5/0468 , A61B5/0452 , G16H50/20 , A61B5/04 , A61B5/0456 , A61B5/00
摘要： Techniques for determining whether a ventricular depolarization is a premature ventricular contraction (PVC) depolarization may include processing circuitry of a medical system identifying an interval from a maximum slope point to a minimum slope point for each of a plurality of ventricular depolarizations and, for each of the plurality of ventricular depolarizations as a current ventricular depolarization, determining that the intervals from the maximum slope point to the minimum slope point for the current ventricular depolarization, a preceding adjacent ventricular depolarization of the plurality of ventricular depolarizations, and a subsequent adjacent ventricular depolarization of the plurality of ventricular depolarizations satisfy one or more slope criteria. The processing circuitry determines that the current ventricular depolarization is a PVC depolarization based on the intervals from the maximum slope point to the minimum slope point satisfying the one or more slope criteria.

42. 发明申请

WO2016134095A1 APPARATUS FOR ATRIAL ARRHYTHMIA EPISODE DETECTION 审中-公开
标题翻译： ATRIAL ARRHYTHMIA EPISODE检测装置
公开(公告)号：WO2016134095A1
公开(公告)日：2016-08-25
申请号：PCT/US2016/018383
申请日：2016-02-18
申请人： MEDTRONIC, INC.
发明人： SARKAR, Shantanu , HANSEN, Daniel L. , NEITZELL, Grant A.
IPC分类号： A61N1/365 , A61B5/04
CPC分类号： A61B5/046 , A61B5/04 , A61B5/04012 , A61B5/04014 , A61B5/04017 , A61B5/0452 , A61B5/0456 , A61B5/0464 , A61B5/686 , A61N1/3624 , A61N1/36507 , A61N1/36592 , A61N1/395 , A61N1/3987
摘要： Techniques and devices for implementing the techniques for identifying noise within a sensing window associated with a cardiac event are described. A implantable medical device may include a plurality of electrodes configured to sense the cardiac signal and a processor configured to determine a sensing window associated with at least one cardiac event in the sensed cardiac signal. The sensing window includes a first portion and a second portion. The processor determines a first derivative signal of the cardiac signal within the sensing window, determines a second derivative signal of the cardiac signal within the sensing window, and identifies a noise event within the sensing window based on an analysis of the first and second derivative signals.
摘要翻译：描述了用于实现用于识别与心脏事件相关联的感测窗口内的噪声的技术的技术和装置。可植入医疗装置可以包括被配置为感测心脏信号的多个电极，以及被配置为确定与感测的心脏信号中的至少一个心脏事件相关联的感测窗口的处理器。感测窗包括第一部分和第二部分。处理器确定感测窗口内的心脏信号的一阶导数信号，确定感测窗口内的心脏信号的二阶导数信号，并且基于第一和第二导数信号的分析来识别感测窗口内的噪声事件。

43. 发明申请

WO2016133799A1 APPARATUS FOR ADJUSTING A THRESHOLD DURING ATRIAL ARRHYTHMIA EPISODE DETECTION IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于在可植入的医疗装置中进行急性心律失常检测期间调整阈值的装置
公开(公告)号：WO2016133799A1
公开(公告)日：2016-08-25
申请号：PCT/US2016/017683
申请日：2016-02-12
申请人： MEDTRONIC, INC.
发明人： SARKAR, Shantanu , HANSEN, Daniel L. , NEITZELL, Grant A. , REILAND, Jerry D. , WYSZYNSKI, Ryan
IPC分类号： A61N1/365 , A61B5/04 , A61N1/39
CPC分类号： A61B5/046 , A61B5/04 , A61B5/04012 , A61B5/04014 , A61B5/04017 , A61B5/0452 , A61B5/0456 , A61B5/0464 , A61B5/686 , A61N1/3624 , A61N1/36507 , A61N1/36592 , A61N1/395 , A61N1/3987
摘要： An implantable medical device and method for determining an atrial arrhythmia event that includes a cardiac sensing device comprising a housing having circuitry positioned therein, a plurality of electrodes electrically coupled to the circuitry to sense a cardiac signal, and a processor configured to generate an initial detection of an atrial arrhythmia event in response to an atrial arrhythmia threshold, determine whether a P-wave occurs during the initial detection, determine an adaptive threshold in response to the P-wave being detected, adjust the atrial arrhythmia threshold in response to the adaptive threshold, and generate a subsequent initial detection of an atrial arrhythmia event using the adjusted atrial arrhythmia threshold.
摘要翻译：一种用于确定房性心律失常事件的可植入医疗装置和方法，其包括心脏感测装置，所述心脏感测装置包括具有放置在其中的电路的壳体，电耦合到所述电路以感测心脏信号的多个电极，以及被配置为产生初始检测的处理器响应于房性心律失常阈值的心房心律失常事件，确定在初始检测期间是否发生P波，响应于检测到的P波确定自适应阈值，响应于自适应阈值调整心房心律失常阈值，并使用调整的心房心律失常阈值产生随后的心房心律失常事件的初始检测。

44. 发明申请

WO2004050185A2 DISCRIMINATING POLYMORPHIC FROM MONOMORPHIC TACHYARRHYTHMIAS 审中-公开
标题翻译：从单体TACHYARRHYTHMIAS分辨多态性
公开(公告)号：WO2004050185A2
公开(公告)日：2004-06-17
申请号：PCT/US2003/038353
申请日：2003-12-03
申请人： MEDTRONIC, INC.
发明人： BROWN, Mark, L. , SARKAR, Shantanu
IPC分类号： A61N1/39
CPC分类号： A61B5/726 , A61B5/0031 , A61B5/046 , A61B5/0464 , A61N1/3956
摘要： Methods and apparatus are provided for discriminating high rate polymorphic QRS complexes from high rate monomorphic QRS complexes to increase the specificity of detection of polymorphic VT and VF employing wavelet transform signal processing of the QRS complexes are disclosed. Wavelet transforms are applied to the sampled amplitude values of a sequence of QRS complexes to develop wavelet transform coefficient (WTC) data sets. At least selected ones of the WTC data sets are processed and comparisons are made to determine a wavelet match score. A determination is made as a function of the wavelet match scores of the series of successive QRS complexes that characterizes the most recent QRS complex as more or less likely to signify polymorphic VT or VF.
摘要翻译：提供方法和装置用于区分来自高速单态QRS复合物的高倍数多态性QRS复合物，以增加使用QRS复合物的小波变换信号处理的多态性VT和VF检测的特异性。将小波变换应用于QRS复合序列的采样振幅值，以开发小波变换系数（WTC）数据集。处理至少选定的WTC数据集，并进行比较以确定小波匹配分数。作为一系列连续QRS复合物的小波匹配分数的函数的确定，其表征最近的QRS复合物或多或少可能表示多态性VT或VF。

45. 发明申请

WO2004050184A3 SYSTEMS AND METHODS FOR DISCRIMINATING POLYMORPHIC FROM MONOMORPHIC TACHYARRHYTHMIAS 审中-公开
公开(公告)号：WO2004050184A3
公开(公告)日：2004-06-17
申请号：PCT/US2003/038341
申请日：2003-12-03
申请人： MEDTRONIC, INC.
发明人： BROWN, Mark, L. , SARKAR, Shantanu
IPC分类号： A61N1/39
摘要： Systems and methods that improving the specificity of discriminating between a monomorphic tachyarrhythmia and a polymorphic tachyarrhythmia are provided that examine frequency content and baseline information of the EGM as discriminatory signatures are disclosed. Particular algorithms of the present invention that are employed to determine frequency content of the QRS complexes are titled the Slope Distribution Metric (SDM) algorithm and the Slope Distribution Composite (SDC) algorithm.

46. 发明申请

WO2023007281A1 FILTER-BASED ARRHYTHMIA DETECTION 审中-公开
公开(公告)号：WO2023007281A1
公开(公告)日：2023-02-02
申请号：PCT/IB2022/056285
申请日：2022-07-07
申请人： MEDTRONIC, INC.
发明人： CHENG, Ya_Jian , WARMAN, Eduardo N. , GILLBERG, Jeffrey M. , KADROLKAR, Abhijit , SARKAR, Shantanu , OUSDIGIAN, Kevin T.
IPC分类号： A61B5/346 , G16H50/20 , A61B5/00
摘要： This disclosure is directed to a medical system and technique for a filter-based approach to arrhythmia detection. In one example, the medical system comprises one or more sensors configured to sense physiological parameter(s); sensing circuitry configured to generate patient data based on the sensed physiological parameter(s), the patient data comprising signal data to represent cardiac activity of the patient; and processing circuitry configured to: detect a cardiac arrhythmia for the patient based on a classification of the signal data in accordance with a machine learning model, wherein the machine learning model comprises filter(s) for at least one portion of the signal data, wherein the at least one filter corresponds to a feature set that maps to the cardiac activity represented by the portion(s) of the signal data; and generate for display output data indicative of a positive detection of the cardiac arrhythmia.

47. 发明申请

WO2022265841A1 ADJUDICATION ALGORITHM BYPASS CONDITIONS 审中-公开
公开(公告)号：WO2022265841A1
公开(公告)日：2022-12-22
申请号：PCT/US2022/031234
申请日：2022-05-27
申请人： MEDTRONIC, INC.
发明人： CHENG, Ya-Jian , LANDMAN, Sean R. , GUNDERSON, Bruce D. , ZIEGLER, Paul D. , SARKAR, Shantanu , OUSDIGIAN, Kevin T. , RAJAGOPAL, Gautham , IPPOLITO, Ekaterina M.
IPC分类号： A61N1/372 , A61B5/316
摘要： This disclosure describes techniques for bypassing an algorithm configured to determine a likelihood of episode data being a false indication of a cardiac episode. A medical device system includes processing circuitry configured to receive episode data and determine, based on satisfaction of one or more bypass conditions of a set of bypass conditions, whether to bypass the algorithm. Responsive to bypassing the algorithm, the processing circuitry stores the episode data as a true indication of the cardiac episode.

48. 发明申请

WO2022231678A1 RESPONSE BY ROBOTIC DEVICE TO AN ACUTE HEALTH EVENT REPORTED BY MEDICAL DEVICE 审中-公开
公开(公告)号：WO2022231678A1
公开(公告)日：2022-11-03
申请号：PCT/US2022/016679
申请日：2022-02-17
申请人： MEDTRONIC, INC.
发明人： NEITZELL, Grant A. , SARKAR, Shantanu , KRAUSE, Paul G. , CHO, Yong K. , OUSDIGIAN, Kevin T. , WYSZYNSKI, Ryan D. , KOCH, Christopher D.
IPC分类号： A61B5/0205 , G16H50/20 , G16H50/70 , G16H80/00
摘要： A device comprising a computer-readable medium having executable instructions stored thereon, configured to be executable by processing circuitry for causing the processing circuitry to: determine that a patient is experiencing or has experienced an acute health event; cause a motor to move a robotic device to a location proximate the patient; cause a sensor of the robotic device to gather physiological data from the patient; confirm that the patient is experiencing or has experienced the acute health event based on the physiological data; and generate an output in response to confirming that the patient is experiencing or has experienced the acute health event.

49. 发明申请

WO2022005747A1 DETERMINING AN EFFICACY OF A TREATMENT PROGRAM 审中-公开
公开(公告)号：WO2022005747A1
公开(公告)日：2022-01-06
申请号：PCT/US2021/037558
申请日：2021-06-16
申请人： MEDTRONIC, INC.
发明人： IPPOLITO, Ekaterina M. , SARKAR, Shantanu , WARMAN, Eduardo N. , LAUER, Joel R.
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/024 , A61B5/053 , A61B5/0538 , A61B5/0816 , A61B5/361 , A61B5/4836 , A61B5/4842 , A61B5/4848 , A61B5/686 , A61B5/7275 , G16H40/60
摘要： This disclosure is directed to devices, systems, and techniques for determining an efficacy of a treatment program. For example, a medical device system includes a medical device including one or more sensors configured to generate a signal that indicates a parameter of a patient. Additionally, the medical device system includes processing circuitry configured to receive data indicative of a user selection of a reference time; determine a plurality of parameter values of the parameter based on a portion of the signal corresponding to a period of time including the reference time. Additionally, the processing circuitry is configured to identify, based on a first set of parameter values, a reference parameter value, calculate a parameter change value, and determine, based on the parameter change value, whether an improvement or a worsening of the patient has occurred responsive to a treatment administered beginning at the reference time.

50. 发明申请

WO2020263568A1 SENSING RESPIRATION PARAMETERS BASED ON AN IMPEDANCE SIGNAL 审中-公开
公开(公告)号：WO2020263568A1
公开(公告)日：2020-12-30
申请号：PCT/US2020/036917
申请日：2020-06-10
申请人： MEDTRONIC, INC.
发明人： SARKAR, Shantanu , CHRISTENSEN, Eric M. , JAYE, Deborah Ann , CHAKRAVARTHY, Niranjan , MORREN, Geert , REILAND, Jerry D.
IPC分类号： A61B5/053 , A61B5/08
摘要： This disclosure is directed to devices, systems, and techniques for identifying a respiration rate based on an impedance signal. In some examples, a medical device system includes a medical device including a plurality of electrodes. The medical device is configured to perform, using the plurality of electrodes, an impedance measurement to collect a set of impedance values, where the set of impedance values is indicative of a respiration pattern of a patient. Additionally, the medical device system includes processing circuitry configured to identify a set of positive zero crossings based on the set of impedance values, identify a set of negative zero crossings based on the set of impedance values, and determine, for the impedance measurement, a value of a respiration metric using both the set of negative zero crossings and the set of positive zero crossings.

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