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41. 发明授权

US06226996B1 Device for controlled cooling of a surface 失效
标题翻译：用于控制冷却表面的装置
公开(公告)号：US06226996B1
公开(公告)日：2001-05-08
申请号：US09413377
申请日：1999-10-06
申请人： Paul J. Weber , Robert S. Bader , Luiz B. Da Silva
发明人： Paul J. Weber , Robert S. Bader , Luiz B. Da Silva
IPC分类号： F17C704
CPC分类号： A61B18/0218 , B05B12/12 , F17C9/02 , F17C13/026 , F17C2221/013 , F17C2221/014 , F17C2221/017 , F17C2223/0161 , F17C2250/032 , F17C2250/0439 , F17C2265/04 , F17C2270/02
摘要： A device is described that uniformly cools a surface to a specified temperature using a mist of cryogenic fluid. The device comprises a cryogenic fluid reservoir, a valve for controllably releasing the fluid through an atomizing nozzle, a non-contact temperature sensor, and a control unit to display the measured temperature and optionally pre-set the desired surface temperature and control the valve. The application of mist can be controlled manually or electronically. This invention provides a portable tool for safely cooling skin for dermatological applications.
摘要翻译：描述了使用低温流体雾将表面均匀地冷却到指定温度的装置。该装置包括低温流体储存器，用于通过雾化喷嘴可控地释放流体的阀，非接触式温度传感器和控制单元，以显示所测量的温度并且可选地预设所需的表面温度并控制阀。雾的应用可以手动或电子控制。本发明提供了用于皮肤病学应用的皮肤安全冷却的便携式工具。

42. 发明授权

US06175669B1 Optical coherence domain reflectometry guidewire 失效
标题翻译：光学相干畴反射导丝
公开(公告)号：US06175669B1
公开(公告)日：2001-01-16
申请号：US09050571
申请日：1998-03-30
申请人： Billy W. Colston , Matthew Everett , Luiz B. Da Silva , Dennis Matthews
发明人： Billy W. Colston , Matthew Everett , Luiz B. Da Silva , Dennis Matthews
IPC分类号： G02B600
CPC分类号： A61B5/6852 , A61B1/00177 , A61B1/00181 , A61B5/0066 , A61B5/0084
摘要： A guidewire with optical sensing capabilities is based on a multiplexed optical coherence domain reflectometer (OCDR), which allows it to sense location, thickness, and structure of the arterial walls or other intra-cavity regions as it travels through the body during minimally invasive medical procedures. This information will be used both to direct the guidewire through the body by detecting vascular junctions and to evaluate the nearby tissue. The guidewire contains multiple optical fibers which couple light from the proximal to distal end. Light from the fibers at the distal end of the guidewire is directed onto interior cavity walls via small diameter optics such as gradient index lenses and mirrored corner cubes. Both forward viewing and side viewing fibers can be included. The light reflected or scattered from the cavity walls is then collected by the fibers, which are multiplexed at the proximal end to the sample arm of an optical low coherence reflectometer. The guidewire can also be used in nonmedical applications.
摘要翻译：具有光学感测能力的导丝基于多路复用光学相干域反射计（OCDR），其允许其在微创医疗中穿过身体时感测动脉壁或其他腔内区域的位置，厚度和结构程序。该信息将用于通过检测血管结点引导导线穿过身体并评估附近的组织。导丝包含多个光纤，其将光从近端耦合到远端。来自导线远端的纤维的光通过诸如梯度折射率透镜和镜像角立方体的小直径光学器件引导到内腔壁上。可以包括前视和侧视纤维。然后从空腔壁反射或散射的光被纤维收集，纤维在近端被多路复用到光学低相干反射计的样品臂。导丝也可用于非医疗应用。

43. 发明授权

US6114348A Method of treating warts using tazarotene 失效
标题翻译：使用他扎罗汀处理疣的方法
公开(公告)号：US6114348A
公开(公告)日：2000-09-05
申请号：US265776
申请日：1999-03-10
申请人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
发明人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
IPC分类号： A61K9/00 , A61K31/455 , A61K31/505 , A61K31/57 , A61K47/10 , A61K31/44 , A61K31/56
CPC分类号： A61K9/0014 , A61K31/455 , A61K31/505 , A61K31/57 , A61K47/10
摘要： A method and composition for topically treating non-metastasizing skin eruptions of warts with tazarotene in a suitable pharmaceutical composition. The compositions can include corticosteroids or fluorouracil.
摘要翻译：一种在合适的药物组合物中用匹萨罗汀局部治疗疣的非转移性皮肤疹的方法和组合物。组合物可以包括皮质类固醇或氟尿嘧啶。

44. 发明授权

US6067996A Nail decoration using ink jets 失效
标题翻译：指甲装饰使用喷墨
公开(公告)号：US6067996A
公开(公告)日：2000-05-30
申请号：US366610
申请日：1999-08-03
申请人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
发明人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
IPC分类号： A45D34/04 , B41J3/407 , A45D29/00
CPC分类号： B41J3/407 , A45D34/04 , A45D2029/005
摘要： Inkjet printing technology is used to apply a selected design on a fingernail or toenail. The nail printing device applies highly detailed, customized, multicolored designs that are scaled to the size and shape of the individual nail. The device comprises an ink jet print head; a holder for aligning the digit or nail, and a control system that contains the nail designs in an electronic digital form, scales and corrects the designs to the individual nail size and shape, and directs the ink jet print head to apply the scaled design to the nail.
摘要翻译：喷墨打印技术用于将选定的设计应用于指甲或趾甲。指甲打印设备应用高度详细，定制化，多彩多姿的设计，其尺寸与单个钉子的尺寸和形状相符。该装置包括喷墨打印头; 用于对准数字或钉子的保持器以及包含电子数字形式的指甲设计的控制系统，将设计缩放并校正为各个钉子的尺寸和形状，并引导喷墨打印头将缩放的设计应用于指甲。

45. 发明授权

US5931166A Fingernail decorating 失效
标题翻译：指甲装饰
公开(公告)号：US5931166A
公开(公告)日：1999-08-03
申请号：US218579
申请日：1998-12-22
申请人： Paul J. Weber , Michael R. Weber , Luiz B. Da Silva
发明人： Paul J. Weber , Michael R. Weber , Luiz B. Da Silva
IPC分类号： A45D34/04 , B41J3/407 , A45D29/00
CPC分类号： B41J3/407 , A45D34/04 , A45D2029/005
摘要： The invention provides a method and an apparatus for decorating or coloring fingernails or toenails. According to the method, a subject's fingernail is scanned to obtain an image and the image is transferred to a computer. The computer then maps out the fingernail surface and scales a selected image or design to fit on the fingernail. This information is then used by the computer to activate an inkjet assembly to print out the stored image on the fingernail surface.
摘要翻译：本发明提供了一种用于装饰或着色指甲或脚趾甲的方法和装置。根据该方法，扫描对象的指甲以获得图像，并将图像传送到计算机。计算机然后映射出指甲表面并缩放选定的图像或设计以适应指甲。该信息随后被计算机使用以激活喷墨组件以将存储的图像打印在指甲表面上。

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