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41. 发明授权

US06276758B1 Surface miner with tilting superstructure for depth control 有权
标题翻译：具有倾斜上部结构的表面矿工进行深度控制
公开(公告)号：US06276758B1
公开(公告)日：2001-08-21
申请号：US09385944
申请日：1999-08-30
申请人： Dieter Hoffmann , Volkmar Schrader , Thomas Stenzel , Hans-Joachim Schombel
发明人： Dieter Hoffmann , Volkmar Schrader , Thomas Stenzel , Hans-Joachim Schombel
IPC分类号： E02F508
CPC分类号： E02F5/26 , B65G41/002 , B65G41/008 , E02F3/181 , E02F7/02 , E02F7/026 , E02F9/028 , E21C41/26 , E21C47/00
摘要： A continuously operating surface miner designed basically with a milling roller for the accurate, selective mining of sedimentary beds. The parameters cutting height, cutting width and feed speed are decisive for the performance capacity of surface miners. How the miner begins a block to be mined, how it finishes it and changes over to a new block to be mined is significant as well. The particular technology that can be used depends essentially on the mobility of the miner and the possibility of the engagement of the milling roller with the material to be mined. A three-caterpillar chassis for the miner and for arranging the milling roller (15a) in front of the said chassis in the direction of mining is provided. The milling roller (15a) is mounted on a transverse frame (15b) and is fastened by same to the superstructure (8) of the miner. High mobility of the miner is achieved due to this arrangement of the milling roller and the use of the chassis. The miner always travels on a clean, freshly cut level, so that natural unevennesses or ditches dug to drain surface water do not interfere with the travel. Another advantage of this design is that the miner can move backward without problems, can strip corners with ease and can also open basin-shaped deposits with a circular feed movement.
摘要翻译：一个连续操作的平面采矿机基本上设计有一个铣刀，用于准确，有选择地开采沉积床。参数切割高度，切割宽度和进给速度对于表面矿工的性能是决定性的。矿工如何开始一个开采的区块，如何完成，并将其切换到一个新的开采区块也是很重要的。可以使用的特定技术基本上取决于矿工的移动性和铣削辊与待开采材料接合的可能性。提供了一种用于矿工的三毛虫底盘，并且用于在挖掘方向上将铣削辊（15a）布置在所述底盘前面。研磨辊（15a）安装在横向框架（15b）上并且被相同地固定到矿工的上部结构（8）上。由于铣削辊的这种布置和底盘的使用，实现了矿工的高移动性。矿工始终保持干净，新鲜切割的水平，以免挖出地表水引起的天然不平或沟渠不妨碍旅行。这种设计的另一个优点是矿工可以向后移动而没有问题，可以轻松地脱落角落，还可以用圆形进给运动打开盆形沉积物。

42. 发明授权

US5602108A Semisynthetic diastereomerically pure N-glycidylanthracyclines, a process for the stereoselective preparation thereof as the use thereof as cytostatics 失效
标题翻译：半合成非对映异构体纯的N-缩水甘油环内酯，其作为细胞抑制剂的用途的立体选择性制备方法
公开(公告)号：US5602108A
公开(公告)日：1997-02-11
申请号：US464468
申请日：1995-06-05
申请人： Manfred Gerken , Monika Grimm , Ernst Raab , Dieter Hoffmann , Reiner Straub
发明人： Manfred Gerken , Monika Grimm , Ernst Raab , Dieter Hoffmann , Reiner Straub
IPC分类号： A61K31/65 , A61K31/70 , A61K31/704 , A61P35/00 , C07B53/00 , C07C15/62 , C07C50/36 , C07H15/252 , C07H15/26 , A61K37/00 , C07M15/24
CPC分类号： C07H15/26 , C07H15/252
摘要： Semisynthetic diastereomerically pure N-glycidylanthracyclines, a process for the stereoselective preparation thereof and the use thereof as cytostatics. The invention relates to anthracyclines having cytostatic activity and the formula I, which are, where appropriate, in the form of a salt with an inorganic or organic acid, ##STR1## in which R.sup.1 is hydrogen or a hydroxyl group,R.sup.2 is hydrogen, a hydroxyl group or an alkyloxy group (C.sub.1 -C.sub.4),R.sup.3 is hydrogen, a hydroxyl group or a structure of the formula II ##STR2## R.sup.4 is CH.sub.2 CH.sub.3, COCH.sub.3, COCH.sub.2 OH, CHOHCH.sub.3 or CHOHCH.sub.2 OH,R.sup.5 is hydrogen, a hydroxyl group, a methoxycarbonyl group or a structure of the formula II,R.sup.6 is hydrogen, an alkyl group (C.sub.1 -C.sub.4), an allyl group, a benzyl group or mono- or di-methyloxy-substituted benzyl group, a tetrahydropyranyl group,R.sup.7 is hydrogen, an alkyl group (C.sub.1 -C.sub.4), an allyl group, a benzyl group or mono- or di-methyloxy-substituted benzyl group andR.sup.8 is a structure of the formula III or IV ##STR3## and to a process for the preparation of these compounds, which comprises reacting an anthracycline derivative of the structure I in whichR.sup.1, R.sup.2 and R.sup.4 are as defined above, andR.sup.3 is hydrogen, a hydroxyl group or a structure of the formula V ##STR4## R.sup.5 is hydrogen, a hydroxyl group, a methoxycarbonyl group or a structure of the formula V andR.sup.6 and R.sup.7 are as defined above, with (R)- or (S)-glycidyl sulfonate.
摘要翻译：半合成非对映体纯N-缩水甘油环素，其立体选择性制备方法及其作为细胞抑制剂的用途。本发明涉及具有细胞抑制活性的蒽环类抗生素和式I，它们在适当的情况下为无机或有机酸形式的盐，其中R 1为氢或羟基，R 2为氢，羟基或烷氧基（C 1 -C 4），R 3是氢，羟基或式II的结构。R 4是CH 2 CH 3，COCH 3，COCH 2 OH，CHOHCH 3或CHOHCH 2 OH，R 5是氢，羟基，甲氧基羰基或式II的结构，R6是氢，烷基（C1-C4），烯丙基，苄基或单 - 或二 - 甲氧基取代的苄基，四氢吡喃基，R7是氢，烷基（C1-C4），烯丙基，苄基或单 - 或二 - 甲氧基取代的苄基，R8是式III或IV的结构，IV和一种制备这些化合物的方法，其包括使结构I的蒽环衍生物与其中R 1，R 2和/ R 4如上定义，并且R 3是氢，羟基或式V R 5的结构是氢，羟基，甲氧基羰基或式V和R 6和R 7的结构如上定义（R） - 或（S） - 磺酰基磺酰基。

43. 发明授权

US4957375A Apparatus for guiding a shaft 失效
标题翻译：用于引导轴的装置
公开(公告)号：US4957375A
公开(公告)日：1990-09-18
申请号：US418531
申请日：1989-10-10
申请人： Dieter Hoffmann
发明人： Dieter Hoffmann
IPC分类号： F16C23/02 , F16B21/00 , F16C17/04 , F16C17/10 , F16C35/02
CPC分类号： F16C35/02 , F16B21/00 , F16C17/04 , F16C17/10
摘要： A shaft is guided axially with respect to position and clearance in a bearing flange. The guidance is adjustable by means of guiding pieces engaging a turned groove of the shaft. The groove has oblique conical sidewalls, and each guiding piece by radial adjustment limits the axial position of a respective sidewall.
摘要翻译：轴相对于轴承法兰中的位置和间隙轴向引导。引导通过与轴的转动槽接合的引导件来调节。槽具有倾斜的圆锥形侧壁，并且通过径向调节的每个引导件限制了相应侧壁的轴向位置。

44. 发明授权

US4914191A Anthracycline derivatives having cytostatic activity 失效
标题翻译：具有细胞抑制活性的蒽环类衍生物
公开(公告)号：US4914191A
公开(公告)日：1990-04-03
申请号：US216199
申请日：1988-07-07
申请人： Peter Hermentin , Michael Paal , Cenek Kolar , Hans P. Kraemer , Dieter Hoffmann , Hans G. Berscheid , Dirk Bottger
发明人： Peter Hermentin , Michael Paal , Cenek Kolar , Hans P. Kraemer , Dieter Hoffmann , Hans G. Berscheid , Dirk Bottger
IPC分类号： A61K31/65 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , C07C45/00 , C07C50/36 , C07C67/00 , C07H15/252
CPC分类号： C07H15/252
摘要： The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I ##STR1## in which the radicals R.sup.1 is hydrogen or a hydroxyl group, R.sup.2 is hydrogen or a hydroxyl group or a structure of the formula II, and R.sup.3 is a hydroxyl group or a structure of the formula II ##STR2## in which R.sup.4 is an aliphatic or aromatic acyl group, with the proviso that at least one of the radicals R.sup.2 and R.sup.3 has a structure of the formula II, which are optionally in the form of a salt of an inorganic or organic acid, as well as to the process for the preparation thereof, and to the use thereof in pharmaceuticals.
摘要翻译：本发明涉及具有细胞抑制活性的新型蒽环类衍生物和其中基团R 1为氢或羟基，R 2为氢或羟基或式II结构的通式Ⅰ“ 羟基或式II II的结构，其中R 4是脂族或芳族酰基，条件是基团R 2和R 3中的至少一个具有式II的结构，其任选在形式的无机或有机酸的盐，以及其制备方法及其在药物中的用途。

45. 发明授权

US4776449A Stacker with connecting conveyor 失效
标题翻译：堆垛机连接输送机
公开(公告)号：US4776449A
公开(公告)日：1988-10-11
申请号：US47691
申请日：1987-05-07
申请人： Dieter Hoffmann , Alfred Hausler , Karl-Heinz Bohse , Reinhard Trumper
发明人： Dieter Hoffmann , Alfred Hausler , Karl-Heinz Bohse , Reinhard Trumper
IPC分类号： B65G41/00 , B65G65/28
CPC分类号： B65G41/002
摘要： A stacker with a connecting conveyor for connecting the stacker with a conveying unit includes a roller rocker which is movably attached to the connecting conveyor and can be placed on the conveying unit or on a traveling vehicle. The roller rocker is placed on the conveying unit or the traveling vehicle in such a way that the connection permits three degrees of freedom.
摘要翻译：具有用于将堆垛机与输送单元连接的连接输送机的堆垛机包括可移动地附接到连接输送机并且可以放置在输送单元上或行进车辆上的滚子摇杆。滚子摇杆以这样的方式被放置在输送单元或行驶车辆上，使得连接允许三个自由度。

46. 发明授权

US4571182A Arrangement for carrying dental implements 失效
标题翻译：携带牙科用具的安排
公开(公告)号：US4571182A
公开(公告)日：1986-02-18
申请号：US573827
申请日：1984-01-24
申请人： Stefan Beier , Franz-Xaver Boeckh , Anton Braun , Thomas Brunner , Dieter Hoffmann , Peter Kiess , Bernd Wagner , Heiner Zinser
发明人： Stefan Beier , Franz-Xaver Boeckh , Anton Braun , Thomas Brunner , Dieter Hoffmann , Peter Kiess , Bernd Wagner , Heiner Zinser
IPC分类号： A61C19/02 , A61B19/02 , A61C19/00 , A61G15/14 , A61C1/14
CPC分类号： A61C19/00 , A61G15/14
摘要： An arrangement for the carrying of dental implements, consisting of a carrying plate arranged on a supporting member, and which has one side facing upwardly including positioning elements provided for the implements on the upwardly facing plate side thereof. The dental implements which are located on the support plate can consist of hand instruments, for example, probes, mirror, tamping instruments, pincettes or the like. Furthermore, the implements can also be formed of cotton receptacles, medication flasks, waste receptacles, as well as worktool, handpiece and anglepiece supports. The positioning elements for the implements can be arranged directly on the carrying plate or also in flat trays, or can even be formed by the flat trays themselves. As the result of an inclination or supplying relative to the horizontal of the upper surface of the carrying plate, the implements which are arranged thereon can be readily surveyed by the dentist or the assistant, and without having to reach thereover, can be easily directly passed over with the hand or by means of a pincette or forceps, or the like.
摘要翻译：一种用于携带牙科用具的装置，包括布置在支撑构件上的承载板，并且其一侧面向上包括设置在工具上的定位元件在其面向上的板侧上。位于支撑板上的牙科工具可以由例如探头，镜子，捣固器械，小针头等手动仪器组成。此外，器具还可以由棉花插座，药物瓶，废物容器以及工具，手机和角件支架形成。用于器具的定位元件可以直接布置在承载板上，也可以布置在平板中，或者甚至可以由平板自身形成。作为相对于承载板的上表面的水平面的倾斜或供给的结果，布置在其上的工具可以容易地由牙医或助手进行测量，而不必到达其上，可以容易地直接通过用手或通过钳子或钳子等等。

47. 发明授权

US4139413A Blow-off device for limiting excess pressure in nuclear power plants, especially in boiling water nuclear power plants 失效
标题翻译：用于限制核电厂，特别是沸水核电站过度压力的排放装置
公开(公告)号：US4139413A
公开(公告)日：1979-02-13
申请号：US784265
申请日：1977-04-04
申请人： Ulrich Simon , Klaus-Dieter Werner , Dieter Hoffmann , Bernd Pontani
发明人： Ulrich Simon , Klaus-Dieter Werner , Dieter Hoffmann , Bernd Pontani
IPC分类号： G21C9/00 , G21C9/004 , G21C9/012
CPC分类号： G21C9/012 , Y02E30/40
摘要： In a blow-off device for limiting excess pressure in nuclear power plants, at least one condensation tube disposed so that a lower outflow end thereof is immersed in a volume of water in a condensation chamber having a gas cushion located in a space above the volume of water, and an upper inflow end of the condensation tube extends out of the volume of water and is connectible to a source of steam that is to be condensed or a steam-air mixture, the outflow end of the condensation tube, for stabilizing the condensation being provided with an assembly of wall parts forming passageways extending in axial direction for subdividing the steam flow and bubbles produced in the volume of water, the passageways of the assembly of wall parts being stepped in axial direction at both axial ends of the assembly of wall parts.
摘要翻译：在用于限制核电站中的过压的吹扫装置中，至少一个冷凝管设置成使得其下流出端浸入一定量的水中，该冷凝室具有位于容积上方的空间中的气垫的水，并且冷凝管的上流入端延伸出水的体积，并且可连接到待冷凝的蒸汽源或蒸汽 - 空气混合物，冷凝管的流出端，用于稳定冷凝装置设置有壁部件组合件，该组件形成沿轴向方向延伸的通道，用于细分蒸汽流和在水体积中产生的气泡，壁部件组件的通道在组件的两个轴向端处沿轴向阶梯状墙壁部件。

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