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41. 发明授权

US11737458B2 Fibrous substrate for capture of gram negative bacteria 有权
公开(公告)号：US11737458B2
公开(公告)日：2023-08-29
申请号：US15561311
申请日：2015-04-01
申请人： Kimberly-Clark Worldwide, Inc.
发明人： David W. Koenig , Amy L. Vanden Heuvel , Vinod Chaudhary , Scott W. Wenzel , Divesh Bhatt , Kathleen Engelbrecht
IPC分类号： A01N25/34 , A61K31/717 , A61K31/74 , D21J1/16 , A61K9/70
CPC分类号： A01N25/34 , A61K31/717 , A61K31/74 , D21J1/16 , A61K9/70 , A01N25/34 , A01N25/10 , A01N25/30
摘要： A fibrous substrate for the removal of Gram negative bacteria (Escherichia coli) from a surface is provided. The fibrous substrate includes a capturing agent, and the affinity of capturing for the Gram negative bacteria allows the fibrous substrate to capture the Gram negative bacteria, thereby removing the Gram negative bacteria from the surface and also inhibiting the spread of the Gram negative bacteria to other surfaces that may contact the fibrous substrate. Of particular advantage, the presence of the capturing agent on the fibrous substrate may help protect against the spread or infection of pathogens without the use of chemicals, such as antiseptics or antibiotics.

42. 发明申请

US20220259527A1 ADHERENT COMPOSITION FOR RNA VIRUSES AND METHOD OF REMOVING RNA VIRUSES FROM A SURFACE 有权
公开(公告)号：US20220259527A1
公开(公告)日：2022-08-18
申请号：US17737549
申请日：2022-05-05
申请人： KIMBERLY-CLARK WORLDWIDE, INC.
发明人： Kathleen C. Engelbrecht , Stacy A. Mundschau , David W. Koenig , Scott W. Wenzel
IPC分类号： C11D17/04 , C11D7/26 , C11D7/32
摘要： A composition for increasing the adherence of RNA viruses can include a liquid carrier, an adherent agent, and a humectant. The adherent agent can be water soluble or dispersible polyester, Methylcellulose, Polyvinylpyrrolidone, and combinations thereof. The composition can be non-antimicrobial. A method for removing RNA viruses from a surface can include providing a composition for increasing the adherence of RNA viruses, applying the composition to the surface, and removing at least some of the composition from the surface to remove RNA viruses from the surface.

43. 发明授权

US10874100B2 Residual disinfectant composition 有权
公开(公告)号：US10874100B2
公开(公告)日：2020-12-29
申请号：US15744091
申请日：2015-07-27
申请人： Kimberly-Clark Worldwide, Inc.
发明人： Amy L. Vanden Heuvel , Douglas R. Hoffman , Jeremy D. Paulsen , Rebecca Vongsa , Paige N. Anunson , Lisa M. Kroll , Corey T. Cunnington , David W. Koenig
IPC分类号： A01N25/10 , A01N25/34 , A61L2/18 , C09D7/61 , C09D7/63 , A01N25/04 , A01N33/12 , A01N37/36 , A01N59/26 , C09D5/14 , A01N25/30 , A01N43/36 , C09D139/06
CPC分类号： A01N25/10 , A01N25/04 , A01N25/34 , A01N33/12 , A01N37/36 , A01N59/26 , A61L2/18 , C09D5/14 , C09D7/61 , C09D7/63 , C09D139/06 , A01N25/10 , A01N37/02 , A01N37/06 , A01N37/36 , A01N41/04 , A01N43/36 , A01N47/28 , A01N59/26 , A01N25/34 , A01N37/02 , A01N37/06 , A01N37/36 , A01N41/04 , A01N43/36 , A01N47/28 , A01N59/26 , A01N33/12 , A01N25/10 , A01N25/34 , A01N33/12 , A01N37/02 , A01N37/06 , A01N37/36 , A01N41/04 , A01N43/36 , A01N47/28 , A01N59/26
摘要： A disinfectant composition that is capable of inactivating non-enveloped viruses as well as other microorganisms, such as gram negative and gram positive bacteria, fungi, parasites, enveloped viruses, etc., is provided. Through selective control over the nature of the acid(s) employed and the overall pH level, the present inventors have discovered that the composition can achieve rapid antiviral efficacy, particularly against non-enveloped viruses. Once applied to a surface (e.g., hard surface), the disinfectant composition forms a film that remains capable of providing residual antiviral activity. Notably, the present inventors have discovered that the use of a vinylpyrrolidone copolymer in combination with a polyquaternary ammonium polymer and cationic surfactant can have a synergistic effect on the stability of the film such that it can also achieve long-term, residual antiviral activity.

44. 发明授权

US10209256B2 Devices and methods for detecting norovirus on surfaces 有权
公开(公告)号：US10209256B2
公开(公告)日：2019-02-19
申请号：US15526939
申请日：2014-11-27
申请人： KIMBERLY-CLARK WORLDWIDE, INC.
发明人： Bao Trong Do , Jonathan Hofmekler , Cesar A. Morales , David W. Koenig , Yang Huang , Aimin He
IPC分类号： G01N33/547 , G01N33/569 , G01N33/558
摘要： Lateral-flow assay and time-resolved fluorescence technologies provide a sensitive tool for detecting norovirus particles in a sample. A flow-through assay device employs norovirus and norovirus G2 antibodies. The lateral-flow assay includes a conjugate pad having conjugated probes. The conjugated probes are particles modified with a binding member that is configured to bind with a norovirus. The particles also have a fluorescent label. A general method of detecting the virus includes (i) preparing a sample with contaminants, (ii) processing the sample and depositing it onto the assay device, and (iii) measuring the fluorescence signal.

45. 发明授权

US10028899B2 Anti-adherent alcohol-based composition 有权
公开(公告)号：US10028899B2
公开(公告)日：2018-07-24
申请号：US15500671
申请日：2015-04-01
申请人： KIMBERLY-CLARK WORLDWIDE, INC.
发明人： Vinod Chaudhary , Scott W. Wenzel , Kathleen C. Engelbrecht , David W. Koenig , Amy L. Vanden Heuvel , Divesh Bhatt , Paige N. Anunson , Stacy A. Mundschau
IPC分类号： A61K8/34 , A61K8/73 , A61K8/02 , A61K8/81 , C09D5/14 , C09D101/28 , A61Q17/00
摘要： The present disclosure is directed to alcohol-based anti-adherent compositions that do not adhere to or attract Gram-negative and Gram-positive bacteria once it is applied to a surface and dried. The composition may include as anti-adherent agents, hydrophilic film-formers such as cellulosics, gums, acrylates, nonionic polymers, and anionic polymers. Examples of anti-adherent agents include Hydroxypropyl methylcellulose, Cellulose gum, Acacia Senegal Gum; Polyacrylate Crosspolymer-11, VP/Dimethyl-aminoethylmethacrylate/Polycarbamyl Polyglycol Ester; Acrylates/Vinyl Neodecanoate Crosspolymer, hydroxypropyl methylcellulose, Hydroxypropylcellulose, Methylcellulose, Propylene Glycol Alginate, Polyacrylate Crosspolymer-6, VP/Polycarbamyl Polyglycol Ester, Acrylates/Steareth-20 Methacrylate Copolymer; Acrylates Copolymer, and any combination thereof. The anti-adherent may be applied to surfaces using a vehicle such as a wipe.

46. 发明申请

US20180199567A1 Residual Disinfectant Composition 审中-公开
公开(公告)号：US20180199567A1
公开(公告)日：2018-07-19
申请号：US15744091
申请日：2015-07-27
申请人： Kimberly-Clark Worldwide, Inc.
发明人： Amy L. Vanden Heuvel , Douglas R. Hoffman , Jeremy D. Paulsen , Rebecca Vongsa , Paige N. Anunson , Lisa M. Kroll , Corey T. Cunnington , David W. Koenig
IPC分类号： A01N25/10 , A01N37/36 , A01N33/12 , C09D5/14 , C09D139/06 , C09D7/63 , A01N25/04 , A01N59/26 , C09D7/61
CPC分类号： A01N25/10 , A01N25/04 , A01N25/34 , A01N33/12 , A01N37/36 , A01N59/26 , A61L2/18 , C09D5/14 , C09D7/61 , C09D7/63 , C09D139/06 , A01N37/02 , A01N37/06 , A01N41/04 , A01N43/36 , A01N47/28
摘要： A disinfectant composition that is capable of inactivating non-enveloped viruses as well as other microorganisms, such as gram negative and gram positive bacteria, fungi, parasites, enveloped viruses, etc., is provided. Through selective control over the nature of the acid(s) employed and the overall pH level, the present inventors have discovered that the composition can achieve rapid antiviral efficacy, particularly against non-enveloped viruses. Once applied to a surface (e.g., hard surface), the disinfectant composition forms a film that remains capable of providing residual antiviral activity. Notably, the present inventors have discovered that the use of a vinylpyrrolidone copolymer in combination with a polyquaternary ammonium polymer and cationic surfactant can have a synergistic effect on the stability of the film such that it can also achieve long-term, residual antiviral activity.

47. 发明授权

US09969885B2 Anti-adherent composition 有权
公开(公告)号：US09969885B2
公开(公告)日：2018-05-15
申请号：US15329611
申请日：2015-04-01
申请人： KIMBERLY-CLARK WORLDWIDE, INC.
发明人： Kathleen C. Engelbrecht , Amy L. Vanden Heuvel , David W. Koenig , Divesh Bhatt , Vinod Chaudhary , Scott W. Wenzel , Stacy A. Mundschau
IPC分类号： C08L101/00 , C08L83/04 , C08J3/02 , A61K8/02
CPC分类号： C08L101/00 , A61K8/0208 , A61K8/731 , A61K8/8117 , A61K8/8152 , A61K8/817 , A61K8/8182 , A61K8/84 , A61K8/891 , A61Q17/005 , C08G77/045 , C08G77/16 , C08G77/46 , C08J3/02 , C08L83/04 , C09D183/04
摘要： Compositions for inhibiting the attachment of microbes to a biotic or abiotic surface are disclosed. The compositions include a carrier and an effective amount of an anti-adherent agent. The anti-adherent agents include Cyclopentasiloxane (and) Dimethiconol, sodium polystyrene sulfonate, Acrylates/Vinyl Neodecanoate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polyquaternium-22, Hydroxypropyl methylcellulose, Polyquaternium-7, Acrylates/Aminoacrylates/C10-30 Alkyl PEG-20 Itaconate Copolymer and combinations thereof. Various delivery vehicles, such as wipes, may be used to deliver the composition to surfaces.

48. 发明申请

US20150125342A1 Controlled Retention and Removal of Biomaterials and Microbes 审中-公开
标题翻译：控制保留和去除生物材料和微生物
公开(公告)号：US20150125342A1
公开(公告)日：2015-05-07
申请号：US14072833
申请日：2013-11-06
申请人： Kimberly-Clark Worldwide, Inc.
发明人： Jose K. Abraham , Kaiyuan Yang , David W. Koenig , Joseph R. Feldkamp
IPC分类号： A61L2/03
CPC分类号： A61L2/03
摘要： A system for removing microbes from a surface, where the microbes are retained by a film, or a film that can prevent microbes from attaching on a surface are described, where the film is electrically connected to a voltage source via surface electrodes. The film can include a tunable dielectric material, and the dielectric constant of the dielectric material can be adjusted to alter the attachment of microbes on the surface when the surface is contacted by the dielectric material. The surface to be contacted can include any surface present in households, water treatment facilities, food industry facilities, soil remediation, or medical facilities. Such surfaces can include tables, countertops, walls, cabinets, doors, door handles, door knobs, etc. The system can also be used to treat any devices used in the aforementioned environments, such as food preparation equipment, medical devices, water cooler tower equipment, etc.
摘要翻译：描述了一种用于从表面除去微生物的系统，其中微生物被膜保留，或者可以防止微生物附着在表面上的膜，其中膜通过表面电极电连接到电压源。膜可以包括可调电介质材料，并且当表面与电介质材料接触时，电介质材料的介电常数可被调节以改变表面上微生物的附着。待接触的表面可以包括家庭中存在的任何表面，水处理设施，食品工业设施，土壤修复或医疗设施。这些表面可以包括桌子，台面，墙壁，橱柜，门，门把手，门把手等。该系统还可以用于处理在上述环境中使用的任何设备，例如食物制备设备，医疗设备，水冷却器塔设备等

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