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41. 发明授权

US08443810B2 Methods of reducing mucus in airways 有权
标题翻译：降低气道粘液的方法
公开(公告)号：US08443810B2
公开(公告)日：2013-05-21
申请号：US11425345
申请日：2006-06-20
申请人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly Shriner
发明人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly Shriner
IPC分类号： A61B19/00 , A61B18/18 , A61F7/00 , A61F7/12
CPC分类号： A61B18/12 , A61B17/22004 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/1485 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

42. 发明授权

US07542802B2 Methods of regenerating tissue in airways 有权
标题翻译：气道再生组织的方法
公开(公告)号：US07542802B2
公开(公告)日：2009-06-02
申请号：US11421429
申请日：2006-05-31
申请人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly Shriner
发明人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly Shriner
IPC分类号： A61B18/18
CPC分类号： A61B18/12 , A61B17/22004 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/1485 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

43. 发明授权

US07273055B2 Methods of treating asthma 有权
标题翻译：治疗哮喘的方法
公开(公告)号：US07273055B2
公开(公告)日：2007-09-25
申请号：US10640967
申请日：2003-08-13
申请人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly Shriner
发明人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly Shriner
IPC分类号： A61B19/00
CPC分类号： A61B18/12 , A61B17/22004 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/1485 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

44. 再颁专利

USRE35974E Method for corneal curvature variations 失效
标题翻译：角膜曲率变化的方法
公开(公告)号：USRE35974E
公开(公告)日：1998-12-01
申请号：US632053
申请日：1996-04-10
申请人： James Davenport , Bryan Loomas , Mark Mathis , Thomas Silvestrini
发明人： James Davenport , Bryan Loomas , Mark Mathis , Thomas Silvestrini
IPC分类号： A61F2/16 , A61F2/14 , A61F9/013 , A61F9/00
CPC分类号： A61F9/013 , A61F2/147
摘要： A method for refractive correction of the eye in order to improve the vision of the eye while not adversely affecting its natural asphericity is described. The method involves determining the amount of correction necessary, selecting an intrastromal corneal ring (ICR) of appropriate thickness to obtain the necessary correction from a selection of ICRs of varying thickness, and inserting the ICR into the corneal stroma. The method may be useful for the correction of mypoia and excessive astigmatism.
摘要翻译：描述了为了改善眼睛的视力而不会不利地影响其天然非球面度的眼睛的屈光矫正的方法。该方法包括确定必要的校正量，选择适当厚度的冠状动脉内角膜环（ICR），以从不同厚度的ICR的选择中获得必要的校正，并将ICR插入角膜基质。该方法可能有助于校正乳腺炎和过度散光。

45. 发明授权

US5318047A Method for corneal curvature variation 失效
标题翻译：角膜曲率变化的方法
公开(公告)号：US5318047A
公开(公告)日：1994-06-07
申请号：US59509
申请日：1993-05-10
申请人： James Davenport , Bryan Loomas , Mark Mathis , Thomas Silvestrini
发明人： James Davenport , Bryan Loomas , Mark Mathis , Thomas Silvestrini
IPC分类号： A61F2/16 , A61F2/14 , A61F9/013 , A61F9/00
CPC分类号： A61F9/013 , A61F2/147
摘要： A method for refractive correction of the eye in order to improve the vision of the eye while not adversely affecting its natural asphericity is described. The method involves determining the amount of correction necessary, selecting an intrastromal corneal ring (ICR) of appropriate thickness to obtain the necessary correction from a selection of ICRs of varying thickness, and inserting the ICR into the corneal stroma. The method may be useful for the correction of myopia and excessive astigmatism.
摘要翻译：描述了为了改善眼睛的视力而不会不利地影响其天然非球面度的眼睛的屈光矫正的方法。该方法包括确定必要的校正量，选择适当厚度的冠状动脉内角膜环（ICR），以从不同厚度的ICR的选择中获得必要的校正，并将ICR插入角膜基质。该方法可用于矫正近视和过度散光。

46. 发明授权

US06632232B1 Corneal vacuum centering guide and dissector 失效
标题翻译：角膜真空定心导向器和解剖器
公开(公告)号：US06632232B1
公开(公告)日：2003-10-14
申请号：US08933855
申请日：1997-09-19
申请人： Bryan Loomas , James Davenport , Mark Mathis
发明人： Bryan Loomas , James Davenport , Mark Mathis
IPC分类号： A61B1732
CPC分类号： A61F2/147 , A61B2017/306 , A61B2017/320052 , A61F9/013
摘要： This invention is a surgical device for producing a generally circular, interlamellar pathway within the corneal stroma of the eye. The device is made up of three major components: a vacuum centering guide having an inner bore which fits at one end against the front of the eye, a barrel which fits within the inner bore of the centering guide and to which is attached the third major component, a generally circular dissecting ring. The dissecting ring is shaped in such way that when an eye surgeon twists the barrel to which the ring is attached, the ring moves through the interlamellar space in the stroma producing the desired channel or pathway. The centering guide may optionally include a ring having one or more pins which firmly engage the cornea's epiphilium. The constituent parts of the surgical device, particularly the dissecting ring, also form a part of this invention. A split ring, or intracorneal ring (“ICR”), is inserted into the intrastromal passageway produced by the inventive device. The ICR changes the shape of the cornea and, in doing so, provides a chosen measure of visual correction.
摘要翻译：本发明是用于在眼睛的角膜基质内产生大致圆形的层间途径的手术装置。该装置由三个主要部件组成：具有内孔的真空定心导向件，该内孔适合于一端靠近眼睛的前端，一个装在中心导向件内孔内的筒体，组件，一般为环形解剖环。解剖环的形状使得当眼外科医生扭转环所附着的圆筒时，环移动通过基质中的层间空间，产生所需的通道或通路。定心引导件可以可选地包括具有一个或多个销的环，其牢固地接合角膜的骨架。手术装置的组成部分，特别是解剖环，也构成本发明的一部分。将裂口环或颈内环（“ICR”）插入由本发明装置产生的基质内通道中。 ICR改变了角膜的形状，在这样做时，提供了一种选择的视力矫正措施。

47. 发明授权

US5403335A Corneal vacuum centering guide and dissector 失效
公开(公告)号：US5403335A
公开(公告)日：1995-04-04
申请号：US214654
申请日：1994-03-15
申请人： Bryan Loomas , James Davenport , Mark Mathis
发明人： Bryan Loomas , James Davenport , Mark Mathis
IPC分类号： A61B17/32 , A61B17/30 , A61F2/14 , A61F9/007 , A61F9/013 , A61B17/24
CPC分类号： A61F2/147 , A61F9/013 , A61B2017/306 , A61B2017/320052
摘要： This invention is a surgical device for producing a generally circular, interlamellar pathway within the corneal stroma of the eye. The device is made up of three major components: a vacuum centering guide having an inner bore which fits at one end against the front of the eye, a barrel which fits within the inner bore of the centering guide and to which is attached the third major component, a generally circular dissecting ring. The dissecting ring is shaped in such way that when an eye surgeon twists the barrel to which the ring is attached, the ring moves through the interlamellar space in the stroma producing the desired channel or pathway. The centering guide may optionally include a ring having one or more pins which firmly engage the cornea's epiphilium. The constituent parts of the surgical device, particularly the dissecting ring, also form a part of this invention. A split ring, or intracorneal ring ("ICR"), is inserted into the intrastromal passageway produced by the inventive device. The ICR changes the shape of the cornea and, in doing so, provides a chosen measure of visual correction.

48. 发明授权

US08985116B2 Layered nasal devices 有权
标题翻译：分层鼻装置
公开(公告)号：US08985116B2
公开(公告)日：2015-03-24
申请号：US11759916
申请日：2007-06-07
申请人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Arthur Ferdinand , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack , Daniel Francis Kennedy
发明人： Rajiv Doshi , Bryan Loomas , Ryan Kendall Pierce , Arthur Ferdinand , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack , Daniel Francis Kennedy
IPC分类号： A61M11/00 , A61M16/06 , A62B23/06 , A61M16/08 , A61M16/20 , A61M16/10 , A61F5/08 , A61M15/08 , A61F5/56
CPC分类号： A62B23/06 , A61F5/08 , A61F5/56 , A61M15/08 , A61M15/085 , A61M16/0616 , A61M16/0688 , A61M16/0866 , A61M16/106 , A61M16/208
摘要： Described herein are nasal devices. In particular, layered nasal respiratory devices are described. Layered nasal device may include a layered airflow resistor that is configured to resist airflow in a first direction more than airflow in a second direction and that includes a flap valve adjacent to a flap valve limiting layer and an adhesive holdfast layer that is configured to secure the layered airflow resistor in communication with the subject's nasal cavity. Methods of using and methods of assembling layered nasal device are also described.
摘要翻译：这里描述的是鼻装置。特别地，描述了分层的鼻呼吸装置。层状鼻装置可以包括分层气流阻力器，其被配置成抵抗第一方向上的气流，而不是沿着第二方向的气流，并且包括与瓣阀限制层相邻的瓣阀和被配置成固定分层气流电阻器与受试者的鼻腔连通。还描述了使用方法和组装分层鼻装置的方法。

49. 发明授权

US08944071B2 Method for treating an asthma attack 有权
标题翻译：治疗哮喘发作的方法
公开(公告)号：US08944071B2
公开(公告)日：2015-02-03
申请号：US13590129
申请日：2012-08-20
申请人： Bryan Loomas , Michael D. Laufer , David P. Thompson
发明人： Bryan Loomas , Michael D. Laufer , David P. Thompson
IPC分类号： A61B19/00 , A61F7/12 , A61B18/18 , A61M29/00 , A61B18/08 , A61B18/02 , A61B18/14 , A61M29/02 , A61N1/40 , A61N5/00 , A61N1/06 , A61B18/00 , A61M25/00 , A61B17/00
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： Methods of increasing gas exchange performed by the lung by damaging lung cells, damaging tissue, causing trauma, and/or destroying airway smooth muscle tone with an apparatus inserted into an airway of the lung are disclosed. The damaging of lung cells, damaging tissue, causing trauma, and/or destroying smooth muscle tone with the apparatus may be accomplished via any one of or combinations of the following: heating the airway; cooling the airway; delivering a liquid to the airway; delivering a gas to the airway; puncturing the airway; tearing the airway; cutting the airway; applying ultrasound to the airway; and applying ionizing radiation to the airway.
摘要翻译：公开了通过用插入肺内气道的装置来增加由肺损伤肺细胞，损伤组织，引起创伤和/或破坏气道平滑肌张力的气体交换的方法。可以通过以下任何一种或组合来实现肺细胞损伤，损伤组织，引起创伤和/或破坏平滑肌张力：加热气道; 冷气道向气道输送液体; 向气道输送气体; 刺穿气道; 撕裂气道; 切断气道; 将超声波应用于气道; 并向气道施加电离辐射。

50. 发明授权

US08020700B2 Packaging and dispensing nasal devices 有权
标题翻译：包装和分配鼻装置
公开(公告)号：US08020700B2
公开(公告)日：2011-09-20
申请号：US12329271
申请日：2008-12-05
申请人： Rajiv Doshi , Bryan Loomas , Enrique F. Mendez , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack
发明人： Rajiv Doshi , Bryan Loomas , Enrique F. Mendez , Arthur G. Sandoval , Jeffrey W. Servaites , Matthew Durack
IPC分类号： B65D83/10 , A61M15/08
CPC分类号： B26D3/10 , B26D3/08 , B26F1/02 , B26F1/3846
摘要： Described herein are packaging systems for nasal devices, and methods of packaging and/or dispensing nasal devices. A packaging system may include one or a plurality of nasal devices removably secured to a support backing, and a dispenser. In some variations an applicator may also be included. Methods of using and methods of assembling packaging systems and dispensers are also described.
摘要翻译：这里描述了用于鼻装置的包装系统，以及包装和/或分配鼻装置的方法。包装系统可以包括可拆卸地固定到支撑背衬的一个或多个鼻部装置和分配器。在一些变型中，还可以包括施用器。还描述了使用方法和组装包装系统和分配器的方法。

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