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    • 44. 发明专利
    • Detector with reduced fluorescence range noise
    • NZ759983A
    • 2021-08-27
    • NZ75998318
    • 2018-11-30
    • ILLUMINA INC
    • PINTO JOSEPHSABOUNCHI POORYAHIRSCHBEIN BERNARDSMITH RANDALLFENG WENYIKHURANA TARUNFUNG TRACY H
    • G01N21/64
    • There is set forth herein a device comprising structure defining a detector surface configured for supporting biological or chemical substances, and a sensor array comprising light sensors and circuitry to transmit data signals using photons detected by the light sensors. The device can include one or more features for reducing fluorescence range noise in a detection band of the sensor array. The device comprises: a structure defining a detector surface for supporting biological or chemical samples; a sensor array comprising light sensors, and circuitry to transmit data signals based on photons detected by the light sensors; and a guide array comprising light guides; wherein light guides of the guide array receive excitation light and emissions signal light from the detector surface, wherein the light guides extend toward respective light sensors of the sensor array and comprise filter material that blocks the excitation light and permits the emissions signal light to propagate toward the respective light sensors, wherein the detector surface includes a reaction recess, the reaction recess comprising an index of refraction and a dimension sufficient to cancel background light energy incident on the detector surface in a detection band of the sensor array. The filter material comprises a metal complex dye comprising a photon emission quencher and a transition metal complex dye.