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41. 发明授权

US08334372B2 Modulation of factor 11 expression 有权
标题翻译：调节因子11表达
公开(公告)号：US08334372B2
公开(公告)日：2012-12-18
申请号：US12580241
申请日：2009-10-15
申请人： Susan M. Freier , Brett P. Monia , Hong Zhang , Chenguang Zhao , Jeffrey R. Crosby , Andrew M. Siwkowski
发明人： Susan M. Freier , Brett P. Monia , Hong Zhang , Chenguang Zhao , Jeffrey R. Crosby , Andrew M. Siwkowski
IPC分类号： C07H21/02 , C07H21/04
CPC分类号： A61K31/7125 , A61K31/366 , A61K31/4365 , A61K31/4545 , A61K31/713 , A61K31/727 , A61K31/737 , C07H21/00 , C12N15/1137 , C12N2310/11 , C12N2310/315 , C12N2310/321 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12Y304/21027
摘要： Disclosed herein are antisense compounds and methods for decreasing Factor 11 and treating or preventing thromboembolic complications in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 11 include thrombosis, embolism, and thromboembolism, such as, deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke. Antisense compounds targeting Factor 11 can also be used as a prophylactic treatment to prevent individuals at risk for thrombosis and embolism.
摘要翻译：本文公开了用于减少因子11并在需要其的个体中治疗或预防血栓栓塞并发症的反义化合物和方法。通过施用靶向因子11的反义化合物可以改善的疾病状况的实例包括血栓形成，栓塞和血栓栓塞，例如深静脉血栓形成，肺栓塞，心肌梗塞和中风。靶向因子11的反义化合物也可用作预防性治疗，以预防患有血栓形成和栓塞风险的个体。

42. 发明授权

US08318266B2 Enhanced copper growth with ultrathin barrier layer for high performance interconnects 有权
公开(公告)号：US08318266B2
公开(公告)日：2012-11-27
申请号：US11470922
申请日：2006-09-07
申请人： Ling Chen , Hua Chung , Barry L. Chin , Hong Zhang
发明人： Ling Chen , Hua Chung , Barry L. Chin , Hong Zhang
IPC分类号： C23C16/00 , C23C14/02 , H05H1/00
CPC分类号： H01L21/28562 , C23C16/34 , C23C16/4411 , C23C16/4412 , C23C16/45504 , C23C16/45508 , C23C16/45512 , C23C16/45525 , C23C16/45544 , C23C16/45563 , C23C16/45582 , H01L21/76843 , H01L21/76846 , H01L21/76871
摘要： A method for depositing a refractory metal nitride barrier layer having a thickness of about 20 angstroms or less is provided. In one aspect, the refractory metal nitride layer is formed by introducing a pulse of a metal-containing compound followed by a pulse of a nitrogen-containing compound. The refractory metal nitride barrier layer provides adequate barrier properties and allows the grain growth of the first metal layer to continue across the barrier layer into the second metal layer thereby enhancing the electrical performance of the interconnect.

43. 发明申请

US20120290728A1 Data card and method for quickly establishing dial-up connection thereof 有权
标题翻译：用于快速建立拨号连接的数据卡和方法
公开(公告)号：US20120290728A1
公开(公告)日：2012-11-15
申请号：US13522519
申请日：2010-09-17
申请人： Hong Zhang
发明人： Hong Zhang
IPC分类号： G06F15/16
CPC分类号： H04W76/02 , H04L29/12216 , H04L29/12311 , H04L61/2015 , H04W28/18 , H04W76/10
摘要： The disclosure provides a method for quickly establishing a dial-up connection by using a data card, which comprises: when a mobile terminal initiates the dial-up connection from a computer, performing both a process of initiating a wireless connection establishment through a Unified Messaging (Um) port and a process of initiating a Dynamic Host Configuration Protocol (DHCP) server through a Remote Messaging (Rm) port at the same time. Compared with the prior art, in the technical solution of the disclosure, the time for initiating the DHCP server by the terminal equipment (TE) is advanced and is identical to the time for initiating the wireless transmission connection establishment, thus the Um side and the Rm side can initiate the dial-up flow at the same time, and the time for waiting DHCP discover messages and the time for waiting the wireless connection establishment overlap, in this way, the purpose of shortening dial-up time and realizing quick dial-up is achieved.
摘要翻译：本公开提供了一种通过使用数据卡快速建立拨号连接的方法，其包括：当移动终端从计算机发起拨号连接时，通过统一消息发起无线连接建立的过程（Um）端口和通过远程消息（Rm）端口同时启动动态主机配置协议（DHCP）服务器的过程。与现有技术相比，在本公开的技术方案中，终端设备（TE）启动DHCP服务器的时间先进，与启动无线传输连接建立的时间相同，因此Um侧和 Rm侧可以同时启动拨号流程，等待DHCP发现消息的时间和等待无线连接建立的时间重叠，从而缩短拨号时间，实现快速拨号，实现了。

44. 发明申请

US20120190708A1 TARGETING NAD BIOSYNTHESIS IN BACTERIAL PATHOGENS 有权
标题翻译：在细菌病毒中靶向NAD生物合成
公开(公告)号：US20120190708A1
公开(公告)日：2012-07-26
申请号：US13383340
申请日：2010-07-12
申请人： Alexander Mackerell, JR. , Hong Zhang , Andrei Osterman , Rohit Kolhatkar
发明人： Alexander Mackerell, JR. , Hong Zhang , Andrei Osterman , Rohit Kolhatkar
IPC分类号： A61K31/4365 , A61P31/04 , A61K31/404 , A61K31/165 , A61K31/197
CPC分类号： C07C251/86
摘要： The emergence of multidrug-resistant pathogens necessitates the search for new antibiotics acting on previously unexplored targets. Nicotinate mononucleotide adenylyltransferase of the NadD family, an essential enzyme of NAD biosynthesis in most bacteria, was selected as a target for structure-based inhibitor development. To this end, the inventors have identified small molecule compounds that inhibit bacterial target enzymes by interacting with a novel inhibitory binding site on the enzyme while having no effect on functionally equivalent human enzymes.
摘要翻译：多药耐药病原体的出现需要寻找新的抗生素作用于以前未开发的靶标。 NadD家族的烟酸单核苷酸腺苷酰基转移酶是大多数细菌中NAD生物合成的必需酶，被选为基于结构的抑制剂发育的靶标。为此，本发明人已经鉴定了通过与酶上的新的抑制性结合位点相互作用而抑制细菌靶酶的小分子化合物，而对功能上等同的人酶没有影响。

45. 发明申请

US20120046934A1 E-Services Translation Utilizing Machine Translation and Translation Memory 有权
标题翻译：电子翻译利用机器翻译和翻译记忆
公开(公告)号：US20120046934A1
公开(公告)日：2012-02-23
申请号：US13052041
申请日：2011-03-18
申请人： Shang-Che CHENG , Alexander Pressman , Hong Zhang , Pei Chiang Ma , Shuan Zhang , Jochen Hummel
发明人： Shang-Che CHENG , Alexander Pressman , Hong Zhang , Pei Chiang Ma , Shuan Zhang , Jochen Hummel
IPC分类号： G06F17/28
CPC分类号： G06F17/289 , G06F17/2827 , G06F17/2836 , G06F17/2854
摘要： A system and method for translating data from a source language to a target language is provided wherein machine generated target translation of a source sentence is compared to a database of human generated target sentences. If a matching human generated target sentence is found, the human generated target sentence may be used instead of the machine generated sentence, since the human generated target sentence is more likely to be a well-formed sentence than the machine generated sentence. The system and method does not rely on a translation memory containing pairs of sentences in both source and target languages, and minimizes the reliance on a human translator to correct a translation generated by machine translation.
摘要翻译：提供了一种用于将数据从源语言翻译成目标语言的系统和方法，其中将源语句的机器生成的目标翻译与人生成的目标句子的数据库进行比较。如果找到匹配的人类生成的目标句子，则可以使用人类生成的目标句子来代替机器生成的句子，因为人类生成的目标句子更可能是比机器产生的句子更好的句子。系统和方法不依赖于包含源语言和目标语言中的句子对的翻译记忆库，并且最小化对人类翻译器的依赖，以纠正机器翻译产生的翻译。

46. 发明申请

US20120043850A1 ELECTRICAL ROTARY JOINT 审中-公开
标题翻译：电动旋转接头
公开(公告)号：US20120043850A1
公开(公告)日：2012-02-23
申请号：US13185749
申请日：2011-07-19
申请人： Boying B. ZHANG , Hong Zhang , Louis D. Violante
发明人： Boying B. ZHANG , Hong Zhang , Louis D. Violante
IPC分类号： H01R39/28
CPC分类号： H01R39/28 , F16H1/28 , F16H55/10
摘要： A simple planetary or epicyclic gear mechanism consists of a sun gear in the center, an internal or ring gear with a common axis with sun gear, and at least one planet gear. The planet gear is located between the sun gear and ring gear, and meshes with both the sun gear and the ring gear. If the ring gear is stationary, when sun gear rotates, the planet gear not only rotates about its axis, its axis also rotate around the axis of sun gear. In stead of employing the sliding motion between the ring and the brush in electrical slip ring, the current invention makes use of a plurality of conductive gears, particularly a planetary gear mechanism, to transfer electrical power, and/or signal(s) between relatively rotatable objects.
摘要翻译：一个简单的行星齿轮或行星齿轮机构由中心的太阳齿轮组成，具有与太阳齿轮的公共轴线的内部或齿圈以及至少一个行星齿轮组成。行星齿轮位于太阳齿轮和齿圈之间，并与太阳齿轮和齿圈啮合。如果环形齿轮是静止的，当太阳齿轮旋转时，行星齿轮不仅围绕其轴线旋转，其轴线也围绕太阳齿轮的轴线旋转。本发明不是在电滑环中使用环和电刷之间的滑动运动，而是利用多个导电齿轮，特别是行星齿轮机构来传递电功率和/或相对的信号可旋转物体。

47. 发明申请

US20110308499A1 METHOD AND DEVICE FOR OPERATING AN INTERNAL COMBUSTION ENGINE 有权
标题翻译：用于操作内燃机的方法和装置
公开(公告)号：US20110308499A1
公开(公告)日：2011-12-22
申请号：US13148349
申请日：2010-01-25
申请人： Uwe Jung , Gerd Rösel , Hong Zhang
发明人： Uwe Jung , Gerd Rösel , Hong Zhang
IPC分类号： F02M51/00
CPC分类号： F02D41/26 , F02D41/2425 , F02D41/2496
摘要： Each cylinder bank of the internal combustion engine is assigned in each case one injection event memory (EES), an injection determining process (EEP) and an injection execution process (EAP). In the respective injection determining process (EEP), desired injection events (EE) are determined for the associated cylinder bank. These injection events are stored in succession in the respectively associated injection event memory (EES). In the respective injection execution process (EAP), injection events (EE) are retrieved in succession from the associated injection event memory (EES) and executed in a sequence in which they were stored in the associated injection event memory (EES) by the associated injection determining process (EEP) (FIFO: first in first out). The in each case next injection event (EE) is executed only after the end of an execution of the in each case previously executed injection event (EE).
摘要翻译：在每种情况下，分配一个喷射事件存储器（EES），喷射确定过程（EEP）和喷射执行过程（EAP））内燃机的每个气缸组。在相应的喷射确定过程（EEP）中，为相关的气缸组确定期望的喷射事件（EE）。这些喷射事件被连续存储在分别关联的喷射事件存储器（EES）中。在相应的注射执行过程（EAP）中，从相关联的注入事件存储器（EES）连续地检索注入事件（EE），并以它们被相关联的注入事件存储器（EES）存储在相关联的注入事件存储器（EES）中的顺序执行）注入确定过程（EEP）（FIFO：先进先出）。在每种情况下，仅在每种情况下先前执行的注入事件（EE）的执行结束之后才执行下一个注入事件（EE）。

48. 发明授权

US08081307B2 Systems and methods for the inspection of stents 有权
标题翻译：检查支架的系统和方法
公开(公告)号：US08081307B2
公开(公告)日：2011-12-20
申请号：US12888337
申请日：2010-09-22
申请人： Ian Cameron , Andrew David Coppin Maw , Hong Zhang , Calden Wloka , Sidney Watterodt , Sang joon Park , Anthony S. Andreacchi , Yung-Ming Chen , Arnoldo M. Currlin , Antonio Garcia , Jason Van Sciver , Bryan D. Glenn
发明人： Ian Cameron , Andrew David Coppin Maw , Hong Zhang , Calden Wloka , Sidney Watterodt , Sang joon Park , Anthony S. Andreacchi , Yung-Ming Chen , Arnoldo M. Currlin , Antonio Garcia , Jason Van Sciver , Bryan D. Glenn
IPC分类号： G01N21/00
CPC分类号： G01N21/952 , A61F2/91 , A61F2/915 , A61F2002/91558 , A61F2002/91575 , A61F2230/0054 , A61F2240/008
摘要： A system and method for inspecting stents can involve an inspection camera to take an image of the stent and a computer system for analyzing the image to determine the presence of any coating defects. The determination can be made by masking out a portion of the stent, identifying deviations from a strut edge, and/or highlighting features protruding from a stent external boundary defining an outer diameter. The image can be taken after a focus feedback camera determines the position of the stent.
摘要翻译：用于检查支架的系统和方法可以包括检查相机以拍摄支架的图像和用于分析图像的计算机系统以确定是否存在任何涂层缺陷。可以通过掩盖支架的一部分，识别与支柱边缘的偏差和/或突出从限定外径的支架外部边界突出的特征来进行确定。在聚焦反馈相机确定支架的位置后，可以拍摄图像。

49. 发明申请

US20110105174A1 METHOD AND APPARATUS FOR TRANSMIT POWER CONTROL FOR MULTIPLE ANTENNA TRANSMISSIONS IN THE UPLINK 有权
标题翻译：用于上行链路中多个天线传输的发射功率控制的方法和装置
公开(公告)号：US20110105174A1
公开(公告)日：2011-05-05
申请号：US12896668
申请日：2010-10-01
申请人： Benoit Pelletier , Lujing Cai , Hong Zhang
发明人： Benoit Pelletier , Lujing Cai , Hong Zhang
IPC分类号： H04W52/04
CPC分类号： H04W52/34 , H04B7/0413 , H04B7/0465 , H04B7/0615 , H04J13/00 , H04L1/1812 , H04W52/146 , H04W52/367 , H04W52/42 , H04W72/0473
摘要： Techniques for transmit power control for multiple antenna transmissions in an uplink are disclosed. A wireless transmit/receive unit (WTRU) generates at least one input stream for transmission and applies a gain factor to each channel. The gain factor is determined based on a reference channel power estimate. The WTRU generates at least two data streams from the input stream for transmission via a plurality of antennas and applies weights to the data streams. The gain factor and/or the weights are controlled such that a transmit power on each antenna is within a maximum allowed value. The WTRU may perform power scaling on a condition that a transmit power on any antenna exceeds the maximum allowed value. The WTRU may scale down an enhanced dedicated channel (E-DCH) dedicated physical data channel (E-DPDCH) first before other channels. For multiple E-DCH streams, the WTRU may calculate an E-DPDCH power offset based on an additional power offset factor due to multiple stream transmission.
摘要翻译：公开了用于上行链路中多天线传输的发射功率控制的技术。无线发射/接收单元（WTRU）生成至少一个用于传输的输入流，并将增益因子应用于每个信道。基于参考信道功率估计来确定增益因子。 WTRU从输入流生成至少两个数据流，以经由多个天线传输，并对数据流应用权重。控制增益因子和/或权重，使得每个天线上的发射功率在最大允许值内。 WTRU可以在任何天线上的发射功率超过最大允许值的条件下执行功率缩放。 WTRU可以在其他信道之前首先缩小增强型专用信道（E-DCH）专用物理数据信道（E-DPDCH）。对于多个E-DCH流，WTRU可以基于由于多流传输而引起的附加功率偏移因子来计算E-DPDCH功率偏移。

50. 发明授权

US07930090B2 Method and device for adapting the valve characteristic of a fuel injection valve 有权
标题翻译：用于适应燃料喷射阀的阀特性的方法和装置
公开(公告)号：US07930090B2
公开(公告)日：2011-04-19
申请号：US12304763
申请日：2007-05-25
申请人： Frank Weiss , Hong Zhang
发明人： Frank Weiss , Hong Zhang
IPC分类号： B60T7/12
CPC分类号： F02D41/2096 , F02D41/1497 , F02D41/2438 , F02D41/2467 , F02D2041/2051
摘要： The method and the device serve to adapt the valve characteristic of a fuel injection valve, which has a piezoelectrically driven nozzle needle and by which fuel is injected directly into the combustion chamber of an internal combustion engine, to production-related or age-related variations in the injection behavior. The activation energy and the needle stroke of the fuel injection valve are controlled in such a way that the engine torque in the case of a fuel injection valve with a reference characteristic would not vary. Here, if an actually occurring variation in the engine torque is detected, then by varying the gradient of the activation-energy/valve-stroke characteristic curve of the fuel injection valve, the engine torque is matched to the engine torque generated with an injection valve with a reference characteristic.
摘要翻译：该方法和装置用于使具有压电驱动的喷嘴针并将燃料直接喷射到内燃机的燃烧室中的燃料喷射阀的阀特性适应于与生产相关的或年龄相关的变化在注射行为。控制燃料喷射阀的活化能和针冲程，使得在具有参考特性的燃料喷射阀的情况下的发动机转矩将不变化。这里，如果检测到发动机转矩的实际发生的变化，则通过改变燃料喷射阀的启动能/阀行程特性曲线的梯度，发动机转矩与由喷射阀产生的发动机转矩相匹配具有参考特性。

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