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41. 发明授权

US5166204A Isoindole derivatives and salts thereof and antitumor agent comprising the same 失效
标题翻译：其衍生物及其销售和包含其的抗菌剂
公开(公告)号：US5166204A
公开(公告)日：1992-11-24
申请号：US605430
申请日：1990-10-30
申请人： Takashi Nagai , Isao Myoukan , Keishi Funaki , Kenji Ohta , Nobuhisa Taya , Shinji Miyabara , Masaaki Shibata , Hidetada Mikami , Takako Hori
发明人： Takashi Nagai , Isao Myoukan , Keishi Funaki , Kenji Ohta , Nobuhisa Taya , Shinji Miyabara , Masaaki Shibata , Hidetada Mikami , Takako Hori
IPC分类号： C07D487/04 , C07D487/14 , C07D491/04 , C07D491/048 , C07D495/04
CPC分类号： C07D487/04 , C07D487/14 , C07D491/04 , C07D495/04
摘要： A novel isoindole derivative represented by general formula [1] or a salt thereof: ##STR1## which has an excellent antitumor activity and low toxicity.
摘要翻译：由通式[1]表示的新型异吲哚衍生物或其盐：其具有优异的抗肿瘤活性和低毒性。

42. 发明授权

US4744985A Novel substances having carcinostatic and immunostimulating activity, process for preparing the same and carcinostatic agent containing the same 失效
标题翻译：具有制癌和免疫刺激活性的新物质，其制备方法和含有其的制癌剂
公开(公告)号：US4744985A
公开(公告)日：1988-05-17
申请号：US180040
申请日：1980-08-21
申请人： Kenzo Tamai , Isamu Saikawa , Takashi Yasuda , Shohachi Murakami , Toyoo Maeda , Hisatsugu Tsuda , Hiroshi Sakai , Masatoshi Sugita , Yoshiko Yamamoto , Hisashi Minami , Takako Hori
发明人： Kenzo Tamai , Isamu Saikawa , Takashi Yasuda , Shohachi Murakami , Toyoo Maeda , Hisatsugu Tsuda , Hiroshi Sakai , Masatoshi Sugita , Yoshiko Yamamoto , Hisashi Minami , Takako Hori
IPC分类号： C12P1/04 , A61K35/74
CPC分类号： C12R1/01 , C12P1/04
摘要： Novel substances having carcinostatic and immunostimulating activity, which are obtained from a culture or its supernatant fluid prepared by culturing bacteria belonging to Fusobacterium genus. Said substances are useful for the treatment of cancerous diseases lower warm-blooded animals. This disclosure concerns such substances and a process for preparing the same and a carcinostatic agent containing the same.
摘要翻译：具有制癌和免疫刺激活性的新型物质，其通过培养属于Fusobacterium属的细菌制备的培养物或其上清液获得。所述物质可用于治疗较低温血动物的癌性疾病。本公开涉及这些物质及其制备方法和含有该物质的制癌剂。

43. 发明授权

US4591558A Novel substances having antitumor and immunostimulating activity, process for preparing the same and antitumor agent containing the same 失效
标题翻译：具有抗肿瘤和免疫刺激活性的新物质，其制备方法和含有该物质的抗肿瘤剂
公开(公告)号：US4591558A
公开(公告)日：1986-05-27
申请号：US619895
申请日：1984-08-06
申请人： Kenzo Tamai , Isamu Saikawa , Takashi Yasuda , Shohachi Murakami , Toyoo Maeda , Hisatsugu Tsuda , Hiroshi Sakai , Masatoshi Sugita , Yoshiko Yamamoto , Hisashi Minami , Takako Hori
发明人： Kenzo Tamai , Isamu Saikawa , Takashi Yasuda , Shohachi Murakami , Toyoo Maeda , Hisatsugu Tsuda , Hiroshi Sakai , Masatoshi Sugita , Yoshiko Yamamoto , Hisashi Minami , Takako Hori
IPC分类号： C12P1/04 , C12P19/26 , C12P21/00 , C12N1/20 , A61K37/00
CPC分类号： C12R1/01 , C12P1/04 , Y10S435/822
摘要： Novel TF-2 substances having antitumor and immunostimulating activity, which are obtained from a culture or its supernatant fluid prepared by culturing bacteria belonging to Fusobacterium genus. Said substances are useful for the treatment of cancerous diseases of the mammals including human beings. This disclosure concerns such substances and a process for preparing the same and an antitumor agent containing the same.
摘要翻译：具有抗肿瘤和免疫刺激活性的新型TF-2物质，其通过培养属于Fusobacterium属的细菌制备的培养物或其上清液获得。所述物质可用于治疗包括人在内的哺乳动物的癌性疾病。本公开涉及这些物质及其制备方法和含有该物质的抗肿瘤剂。

44. 发明授权

US4547462A Process for preparing substance having carcinostatic and immunostimulating activity 失效
标题翻译：制备具有制癌和免疫刺激活性的物质的方法
公开(公告)号：US4547462A
公开(公告)日：1985-10-15
申请号：US523438
申请日：1983-08-16
申请人： Kenzo Tamai , Isamu Saikawa , Takashi Yasuda , Shohachi Murakami , Toyoo Maeda , Hisatsugu Tsuda , Hiroshi Sakai , Masatoshi Sugita , Yoshiko Yamamoto , Hisashi Minami , Takako Hori
发明人： Kenzo Tamai , Isamu Saikawa , Takashi Yasuda , Shohachi Murakami , Toyoo Maeda , Hisatsugu Tsuda , Hiroshi Sakai , Masatoshi Sugita , Yoshiko Yamamoto , Hisashi Minami , Takako Hori
IPC分类号： C12P1/02 , A61K35/74 , A61K38/00 , A61P35/00 , A61P37/04 , C07G11/00 , C07K14/005 , C07K14/195 , C07K14/41 , C12P1/04 , C12P21/00 , C12R1/01 , C12P19/00
CPC分类号： A61K35/74 , C12P1/04 , Y10S435/822
摘要： This invention relates to a process for producing a TF-500 substance having carcinostatic and immunostimulating activities, which comprises subjecting organisms belonging to the Fusobacterium genus to extraction treatment with a dialkyl sulfoxide and obtaining said TF-500 substance from the resulting extract.
摘要翻译：本发明涉及制备具有制癌和免疫刺激活性的TF-500物质的方法，该方法包括使属于所述Fusobacterium属的生物体用二烷基亚砜进行提取处理，并从所得提取物中获得所述TF-500物质。

45. 发明授权

US4460774A 1-(4-Aminobenzyl)-2,3-dioxopiperazine derivatives, acid addition salts thereof and process for producing same 失效
标题翻译： 1-（4-氨基苄基）-2,3-二氧代哌嗪衍生物及其酸加成盐及其制备方法
公开(公告)号：US4460774A
公开(公告)日：1984-07-17
申请号：US348271
申请日：1982-02-12
申请人： Takako Hori , Chosaku Yoshida , Yasuo Kiba , Ryuko Takeno , Joji Nakano , Jun Nitta , Sumiko Kishimoto , Shohachi Murakami , Hisatsugu Tsuda , Isamu Saikawa
发明人： Takako Hori , Chosaku Yoshida , Yasuo Kiba , Ryuko Takeno , Joji Nakano , Jun Nitta , Sumiko Kishimoto , Shohachi Murakami , Hisatsugu Tsuda , Isamu Saikawa
IPC分类号： A61K31/495 , A61P35/00 , C07D241/08 , C07D241/20 , C07D401/06 , C07D401/10 , C07D401/14 , C07D403/06 , C07D403/10 , C07D403/14 , C07D405/14 , C07D417/10 , C07D403/12
CPC分类号： C07D241/08
摘要： A 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative represented by the formula: ##STR1## and an acid addition salt thereof have excellent carcinostatic activity but a low toxicity. Therefore, said compounds are useful as medicines and also as intermediates.
摘要翻译：由下式表示的1-（4-氨基苄基）-2,3-二氧代哌嗪衍生物及其酸加成盐具有优异的制癌活性，但毒性低。因此，所述化合物可用作药物，也可用作中间体。

46. 发明授权

US09401975B2 Terminal and codec mode selection method 有权
标题翻译：终端和编解码方式选择方法
公开(公告)号：US09401975B2
公开(公告)日：2016-07-26
申请号：US13880806
申请日：2011-10-26
申请人： Takako Hori , Hiroyuki Ehara
发明人： Takako Hori , Hiroyuki Ehara
IPC分类号： H04W28/18 , H04L29/06 , H04W76/02 , H04W88/18
CPC分类号： H04L69/08 , H04L69/22 , H04L69/24 , H04W28/18 , H04W36/0083 , H04W76/10 , H04W76/12 , H04W84/045 , H04W88/181
摘要： A terminal is provided that determines the status of a communications and selecting an appropriate codec mode without applying a load to either a network or terminals, by using information held by the terminal as negotiation information. User Equipment (UE) sends to a partner the codec mode selected from a plurality of candidate codec modes notified by the partner, when communications commence. The UE includes a wireless receiver that receives a first information relating to the characteristics of a network to which the partner is currently connected; an information comparison unit that compares the first information and a second information relating to the characteristics of the network that the UE is currently connected to, and decides the communications format; and a mode determination unit that selects the codec mode to be used, from among the candidates and based on the decided communications format.
摘要翻译：提供终端，通过使用由终端保持的信息作为协商信息，确定通信的状态并选择适当的编解码器模式，而不向网络或终端施加负载。当通信开始时，用户设备（UE）向对方发送从伙伴通知的多个候选编解码器模式中选择的编解码器模式。 UE包括无线接收机，其接收与伙伴当前连接的网络的特性相关的第一信息; 信息比较单元，其比较所述第一信息和与所述UE当前连接的所述网络的特性相关的第二信息，并且决定所述通信格式; 以及模式确定单元，其从候选中选择要使用的编解码器模式，并且基于所确定的通信格式。

47. 发明授权

US09288792B2 Network node, terminal, bandwidth modification determination method and bandwidth modification method 有权
标题翻译：网络节点，终端，带宽修改确定方法和带宽修改方法
公开(公告)号：US09288792B2
公开(公告)日：2016-03-15
申请号：US14123333
申请日：2012-05-25
申请人： Takako Hori , Hiroyuki Ehara
发明人： Takako Hori , Hiroyuki Ehara
IPC分类号： H04M1/00 , H04W72/04 , H04W76/04 , H04W88/18
CPC分类号： H04W36/0022 , H04W72/04 , H04W76/22 , H04W88/181
摘要： The objective of the present invention is to suppress deterioration of call quality caused by transcoding without interrupting a call even if a codec used by one of the terminals during communication is changed. A modification determination unit, in the case of detecting a modification of a codec used by one terminal of two terminals, determines whether or not to constrain the bandwidth of the first codec using a first codec of the other terminal and a second codec after modification by the first-mentioned one of the terminals. A signaling generation unit transmits, to the other terminal, signaling for limiting the bandwidth if the bandwidth is to be limited.
摘要翻译：本发明的目的在于，即使通信中的终端之一使用的编解码器被改变，也可以抑制代码转换引起的呼叫质量的恶化，而不会中断呼叫。在检测到由两个终端的一个终端使用的编解码器的修改的情况下，修改确定单元确定是否使用另一终端的第一编解码器限制第一编解码器的带宽，并且修改后由第二编解码器首先提到的一个终端。如果要限制带宽，则信令生成单元向另一终端发送用于限制带宽的信令。

48. 发明授权

US07957344B2 Path setting method, mobile terminal, and path managing device 有权
标题翻译：路径设置方法，移动终端和路径管理设备
公开(公告)号：US07957344B2
公开(公告)日：2011-06-07
申请号：US11658498
申请日：2005-07-28
申请人： Jun Hirano , Takako Hori
发明人： Jun Hirano , Takako Hori
IPC分类号： H04B7/212
CPC分类号： H04W36/18 , H04L45/04 , H04L45/302 , H04L47/14 , H04L47/24 , H04L47/70 , H04L47/724 , H04L47/767 , H04L47/824 , H04W36/02 , H04W40/28 , H04W40/36 , H04W76/20
摘要： A technique is disclosed, by which a mobile terminal (mobile node) performing handover can quickly and continuously receive after the handover the additional services as it has been receiving before the handover. According to this technique, MN (mobile node; mobile terminal) 10 transmits a message including a session identifier or the like of a path 24 to QNE (proxy) 68 under the condition connected to AR (access router) 21 before the handover. QNE 62 and QNE 63 on a path 34 where this message is transferred are present on the path 24, and its own interface address is added to the message. On the other hand, QNE 67 is not present on the path 24 and transfers the message as it is. As a result, QNE (proxy) 68 determines QNE 63 as a crossover node and turns the path upstream from QNE 63 to an identical path, while a path 35 as changed from a downstream path can be set as a path to be used by MN after the handover.
摘要翻译：公开了一种技术，通过该技术，执行切换的移动终端（移动节点）可以在切换之后快速且连续地接收在切换之前已经接收的附加服务。根据这种技术，MN（移动节点;移动终端）10在切换之前在连接到AR（接入路由器）21的条件下向QNE（代理）68发送包括路径24的会话标识符等的消息。路径34上的路径34上的QNE 62和QNE 63存在于路径24上，其自身的接口地址被添加到消息中。另一方面，QNE 67不存在于路径24上，并且原样传送消息。结果，QNE（代理）68将QNE 63确定为交叉节点，并将QNE63上游的路径转换到相同的路径，而从下游路径改变的路径35可以被设置为由MN使用的路径交接后。

49. 发明申请

US20070217363A1 COMMUNICATION HANDOVER METHOD, COMMUNICATION MESSAGE PROCESSING METHOD, PROGRAM FOR CAUSING COMPUTER TO EXECUTE THESE METHODS, AND COMMUNICATION SYSTEM 审中-公开
标题翻译：通信切换方法，通信消息处理方法，用于导致计算机执行这些方法的程序和通信系统
公开(公告)号：US20070217363A1
公开(公告)日：2007-09-20
申请号：US10598328
申请日：2005-02-24
申请人： Toyoki Ue , Takako Hori
发明人： Toyoki Ue , Takako Hori
IPC分类号： H04L12/56
CPC分类号： H04L47/2441 , H04L12/66 , H04L47/14 , H04L47/15 , H04L47/70 , H04L47/767 , H04L47/824 , H04L47/825 , H04W4/00 , H04W8/26 , H04W36/0016 , H04W36/02 , H04W36/30 , H04W40/02 , H04W80/04 , H04W84/12 , H04W92/02
摘要： Disclosed is a technique which enables a mobile node to promptly and continuously get an additional service (e.g., QoS guarantee) before and after the handover. According to the technique, a mobile terminal (MN 10) determines execution of a handover between subnets based on a predetermined condition, configures an NCoA, and acquires information on an adjoining mQNE (a node capable of changing a QoS path) 41 on the QoS path of the MN 10. The MN sends an FBU message and adjacent mQNE information to an oAR 21. The oAR forwards the adjacent mQNE information received from the MN, together with an HI message, to an nAR 31, which establishes a (C)QoS path with the mQNE for the MN based on the adjacent mQNE information.
摘要翻译：公开了一种能够使移动节点在切换之前和之后迅速且连续地获得附加服务（例如，QoS保证）的技术。根据该技术，移动终端（MN 10）基于预定条件确定子网之间的切换的执行，配置NCoA，并且获取关于QoS的邻接mQNE（能够改变QoS路径的节点）41的信息 MN向MN发送FBU消息和相邻mQNE信息.OAR将从MN接收的相邻mQNE信息连同HI消息一起转发到nAR 31，该nAR 31建立（C）基于相邻mQNE信息的具有MN的mQNE的QoS路径。

50. 发明申请

US20070133463A1 Communication handover method, communication handover program, and communication system 审中-公开
标题翻译：通信切换方法，通信切换程序和通信系统
公开(公告)号：US20070133463A1
公开(公告)日：2007-06-14
申请号：US10577264
申请日：2004-10-29
申请人： Takako Hori , Keigo Asou
发明人： Takako Hori , Keigo Asou
IPC分类号： H04Q7/00
CPC分类号： H04W8/085 , H04W8/26 , H04W36/0011 , H04W36/0016 , H04W80/00 , H04W80/04
摘要： A technique which realizes an efficient handover by reducing loads on a mobile node and an access router and communication traffics thereof while keeping a packet loss rate in a fast handover technology is disclosed, and according to that technique, a mobile node (MN 10) has a correspondence relationship between information (link layer address of an AP) on an access point (AP 22, 23, 32, 33) and information (link layer address of an AR, and a network prefix and a prefix length of a subnet 20, 30 to which the AR belongs) on an access router (AR 21, 31) having control over the AP, and, by referring to the correspondence relationship, generates an NCoA of a subnet which is the destination of movement in L2 handover between different subnets, does not change an NCoA and executes only the L2 handover in the L2 handover in the same subnet, and performs a conventional fast handover when there is no correspondence relationship relating to an AP at the destination of the L2 handover.
摘要翻译：公开了一种通过减少移动节点和接入路由器上的负载来实现有效切换的技术，并且在保持快速切换技术中的分组丢失率的同时进行其通信业务，并且根据该技术，移动节点（MN 10）具有接入点（AP 22,23,32,33）的信息（AP 22的链路层地址）与信息（AR的链路层地址，网络前缀和子网20的前缀长度）之间的对应关系， 30），具有对AP的控制的接入路由器（AR 21,31），并且通过参考对应关系生成作为不同子网之间的L2切换中的移动目的地的子网的NCoA 不改变NCoA并且仅在相同子网中的L2切换中仅执行L2切换，并且当在L2切换的目的地处没有与AP相关的对应关系时，执行传统的快速切换。

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