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41. 发明授权

US07374726B2 Chemical reactor 失效
标题翻译：化学反应器
公开(公告)号：US07374726B2
公开(公告)日：2008-05-20
申请号：US10694810
申请日：2003-10-29
申请人： Tadashi Sano , Ryo Miyake , Akira Koide , Takeshi Harada
发明人： Tadashi Sano , Ryo Miyake , Akira Koide , Takeshi Harada
IPC分类号： B01J10/00 , B01L3/02
CPC分类号： B01F13/0062 , B01F3/0807 , B01F5/0453 , B01F5/0682 , B01F13/0066 , B01F2005/0031 , B01J19/0093 , B01J2219/00837 , B01J2219/0084 , B01J2219/00891 , B01J2219/00923 , B01L3/5027 , B01L2200/0636 , G01N35/08 , Y10T137/2224 , Y10T137/2564 , Y10T436/255
摘要： In a chemical reactor, a gas and a liquid which are in trace volumes are used to produce air bubbles and thus increase the interface area between the gas and liquid, substantially enhancing the efficiency of reaction between the gas and liquid. The chemical reactor comprises the following: a sheath flow forming block which forms a plurality of alternating sheath flows with two mutually unmixable fluids; a plurality of inlet ports through which said two fluids flow into the sheath flow forming block; a contraction zone which simultaneously contracts a plurality of sheath flows formed in the sheath flow forming block; and reaction flow channels each of which is connected with said contraction zone and is smaller in width than the sheath flow forming block.
摘要翻译：在化学反应器中，使用微量的气体和液体来产生气泡，从而增加了气体和液体之间的界面面积，从而显着提高了气体和液体之间的反应效率。化学反应器包括以下：鞘流形成块，其形成具有两个相互不可混合流体的多个交替护套流; 多个入口，所述两种流体通过所述入口流入所述鞘流形成块; 收缩区，其同时收缩形成在鞘流形成块中的多个鞘流; 以及每个与所述收缩区连接的反应流动通道，并且宽度小于鞘流形成块。

42. 发明申请

US20070238162A1 Measuring apparatus for interaction of biomolecule 失效
标题翻译：生物分子相互作用的测量装置
公开(公告)号：US20070238162A1
公开(公告)日：2007-10-11
申请号：US11214948
申请日：2005-08-31
申请人： Tetsuro Miyamoto , Hiroyuki Takei , Shigenori Togashi , Ryo Miyake
发明人： Tetsuro Miyamoto , Hiroyuki Takei , Shigenori Togashi , Ryo Miyake
IPC分类号： C12M3/00
CPC分类号： G01N21/253 , G01N21/553 , G01N35/028 , G01N35/1095
摘要： In a measuring apparatus for biomolecule interaction, a fine particle sensor surface is dipped in a buffer solution in a reaction vessel to conduct spectral measurement by way of optical fibers. The buffer solution in the reaction vessel is made to enter an upper reaction vessel and discharged from a flow channel. Air is injected from a flow channel to inject a specimen from the discharge port to the reaction vessel. Then the specimen is sucked into the reaction vessel and brought into contact with the sensor surface where a ligand and an analyte in the specimen are bonded. Bonding is measured by a spectrophotometer through the optical fibers. A buffer solution is injected from the injection flow channel into the reaction vessel and the specimen is discharged out of the flow channel. The dissociation process in which the biomolecules are dissociated along with lowering of the concentration is measured.
摘要翻译：在用于生物分子相互作用的测量装置中，将细颗粒传感器表面浸入反应容器中的缓冲溶液中以通过光纤进行光谱测量。将反应容器中的缓冲溶液进入上反应容器并从流动通道排出。空气从流动通道注入，将样品从排放口注入反应容器。然后将样品吸入反应容器中，并与样品中的配体和分析物结合的传感器表面接触。通过分光光度计通过光纤测量粘合。将缓冲溶液从注射流通道注入反应容器中，并将样品从流动通道排出。测量其中生物分子随浓度降低而解离的解离过程。

43. 发明授权

US07204961B2 Liquid feed apparatus and automatic analyzing apparatus 失效
标题翻译：液体进料装置和自动分析装置
公开(公告)号：US07204961B2
公开(公告)日：2007-04-17
申请号：US09259306
申请日：1999-03-01
申请人： Akira Koide , Ryo Miyake , Takao Terayama , Hiroshi Mitsumaki , Tomonari Morioka
发明人： Akira Koide , Ryo Miyake , Takao Terayama , Hiroshi Mitsumaki , Tomonari Morioka
IPC分类号： B01L3/02 , G01N1/10 , F04B23/06 , F16K16/00 , F16K7/07
CPC分类号： F04B43/043 , F04B53/1042 , Y10T137/87788 , Y10T137/87893 , Y10T436/2575
摘要： Provided is a liquid feed apparatus for feeding liquid by operating a diaphragm at a high frequency, in which an inlet valve and an outlet valve are integrally incorporated with a liquid feed chamber, the positions of the valve are shifted into peripheral parts of the liquid feed chamber so as to allow fluid to smoothly flow from the inlet to the outlet in order to prevent air bubbles from causing pressure fluctuation during liquid feed, from remaining in the liquid feed chamber. Further, the valve has a center beam structure in which a protrusion having a height greater than several micron meters, is formed in the seat part of the valve so as to deform a center beam for pressurizing the valve in order to enhance the shut-off ability of the valve, and the center beam has a small surface area in the direction of displacement of the valve.
摘要翻译：本发明提供一种液体供给装置，其通过以高频操作隔膜，其中入口阀和出口阀与液体供给室一体地结合在一起，阀的位置移动到液体进料的周边部分以允许流体从入口到出口平滑地流动，以防止气泡在液体进料期间引起压力波动，从而保留在液体进料室中。此外，阀具有中心梁结构，其中高度大于几微米的突起形成在阀的阀座部分中，以便使用于加压阀的中心梁变形，以便增强切断阀的能力和中心梁在阀的位移方向上具有小的表面积。

44. 发明申请

US20050192759A1 Computer program for designing treating member and system for providing service using the program 审中-公开
标题翻译：用于设计治疗成员和系统的计算机程序，用于使用程序提供服务
公开(公告)号：US20050192759A1
公开(公告)日：2005-09-01
申请号：US10986804
申请日：2004-11-15
申请人： Ryo Miyake , Toshio Otaguro , Ryoji Okada , Naoya Sasaki
发明人： Ryo Miyake , Toshio Otaguro , Ryoji Okada , Naoya Sasaki
IPC分类号： G01N37/00 , B01L3/00 , G06F17/50 , G06F17/60 , G06F19/00 , G01N33/48
CPC分类号： G06F17/50 , B01L3/5027 , G06Q50/24
摘要： A computer program embodied on a computer readable medium for designing a treating member contains a first code segment adapted to acquiring a piece of input information containing a treatment sequence; and a second code segment adapted to designing a flow path along which a sample moves, based on the piece of input information.
摘要翻译：包含在用于设计治疗部件的计算机可读介质上的计算机程序包含适于获取包含处理序列的输入信息的第一代码段; 以及第二代码段，其适于基于所述输入信息来设计样本移动所沿着的流动路径。

45. 发明授权

US4983038A Sheath flow type flow-cell device 失效
标题翻译：护套流式流通池装置
公开(公告)号：US4983038A
公开(公告)日：1991-01-08
申请号：US178651
申请日：1988-04-07
申请人： Hiroshi Ohki , Ryo Miyake , Isao Yamazaki , Fujiya Takahata
发明人： Hiroshi Ohki , Ryo Miyake , Isao Yamazaki , Fujiya Takahata
IPC分类号： B01F13/00 , G01N15/14
CPC分类号： G01N15/1404 , B01F13/0062
摘要： A sheath flow type flow-cell device for photo-particle-analyzer comprises a substantially flat top surface, at least one first inlet for sheath fluid, at least one first flow passage communicated with the at least one first inlet and contracted toward downstream to be a straight capillary flow passage, a discharge port provided at a terminal end of the straight capillary flow passage, a second inlet for sample fluid, a second flow passage for sample fluid communicated with the second inlet and contracted toward downstream, and coupling portions for sealingly coupling with the particle photo-analyzer. The second flow passage is opened within the at least one first flow passage so as to keep a part of the at least one first flow passage above and below an opening of the second flow passage. The opening is faced in the same direction as the straight capillary flow passage. A wall portion on which the opening locates is rounded. The wall portion is further chamfered and a pair of projections are extended from the wall portion.

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