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41. 发明专利

JP2006188672A Radical inhibitor 审中-公开
标题翻译：放射性抑制剂
公开(公告)号：JP2006188672A
公开(公告)日：2006-07-20
申请号：JP2005351866
申请日：2005-12-06
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： OKU KAZUYUKI , KUBOTA MICHIO , FUKUDA SHIGEHARU , MIYAKE TOSHIO
IPC分类号： C09K15/06 , A23B4/08 , A23K1/16 , A23L3/3562 , A61K8/60 , A61K31/355 , A61K31/375 , A61K31/7016 , A61P17/00 , A61P17/10 , A61P27/02 , A61P39/06 , A61Q1/02 , A61Q1/04 , A61Q1/10 , A61Q5/00 , A61Q11/00 , A61Q15/00 , A61Q19/00 , A61Q19/10 , C09K15/08
摘要： PROBLEM TO BE SOLVED: To provide a radical inhibitor, which is used to prevent the deterioration of the quality of a composition caused by radical formation, to provide a process of inhibiting radical formation using the above inhibitor and also to provide a composition being inhibited in radical formation. SOLUTION: The process of inhibiting radical formation comprises developing a radical inhibitor containing a sugar derivative of α,α-trehalose as an effective component and mixing the above inhibitor into a composition. The conventional problem of deterioration of a quality of a composition caused by radical formation is solved by providing the above composition where the radical formation is inhibited. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：提供用于防止由自由基形成引起的组合物质量劣化的自由基抑制剂，以提供使用上述抑制剂抑制自由基形成的方法，并提供组合物被自由基形成抑制。解决方案：抑制自由基形成的过程包括开发含有α，α-海藻糖的糖衍生物作为有效成分的自由基抑制剂，并将上述抑制剂混合到组合物中。由自由基形成引起的组合物质量劣化的常规问题通过提供抑制自由基形成的上述组成来解决。版权所有（C）2006，JPO＆NCIPI

42. 发明专利

JP2006045496A Starch paste and method for producing the same 有权
标题翻译：淀粉及其生产方法
公开(公告)号：JP2006045496A
公开(公告)日：2006-02-16
申请号：JP2005127337
申请日：2005-04-26
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： OKA IWATARO , HAYAKAWA NORIKO , NISHIMOTO TOMOYUKI , FUKUDA SHIGEHARU , MIYAKE TOSHIO
IPC分类号： C09J103/02
摘要： PROBLEM TO BE SOLVED: To obtain a new starch paste having a low gelatinization degree and a low molecular weight and to provide a method for producing the same.
SOLUTION: The starch paste has
摘要翻译：待解决的问题：获得具有低糊化度和低分子量的新型淀粉糊，并提供其制备方法。解决方案：淀粉糊具有<50％的淀粉糊化度，20,000-50,000道尔顿重均分子量和在约100平均聚合度的葡萄糖的平均聚合度下在异淀粉酶消化产物的凝胶过滤色谱中显示峰的洗脱图案，约50至约10个葡萄糖平均聚合度的温和肩膀。提供了其制造方法。版权所有（C）2006，JPO＆NCIPI

43. 发明专利

JP2004154014A Thermostable kojibiose phosphorylase 有权
公开(公告)号：JP2004154014A
公开(公告)日：2004-06-03
申请号：JP2002320576
申请日：2002-11-01
申请人： Bio Oriented Technol Res Advancement Inst , Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所 , 生物系特定産業技術研究推進機構
发明人： YAMAMOTO TAKUO , MUKAI KAZUHISA , NAKADA TETSUYA , KUBOTA MICHIO , FUKUDA SHIGEHARU , KURIMOTO MASASHI , TSUJISAKA YOSHIO
IPC分类号： C12N15/09 , C12N9/12
摘要： PROBLEM TO BE SOLVED: To provide a thermostable kojibiose phosphorylase, and to provide a method for producing the enzyme. SOLUTION: A solution is achieved by the following. The novel enzyme has significantly raised reaction optimum temperature and thermostability as compared with those of a wild type kojibiose phosphorylase. The method for producing the enzyme comprises culturing a DNA encoding the enzyme and a microorganism producing the enzyme in a nutrient culture medium and collecting the produced enzyme from the resultant cultured product. COPYRIGHT: (C)2004,JPO

44. 发明专利

JP2004154013A High-polymerization oligosaccharide-forming kojibiose phosphorylase 有权
公开(公告)号：JP2004154013A
公开(公告)日：2004-06-03
申请号：JP2002320569
申请日：2002-11-01
申请人： Bio Oriented Technol Res Advancement Inst , Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所 , 生物系特定産業技術研究推進機構
发明人： YAMAMOTO TAKUO , MUKAI KAZUHISA , NAKADA TETSUYA , KUBOTA MICHIO , FUKUDA SHIGEHARU , KURIMOTO MASASHI , TSUJISAKA YOSHIO
IPC分类号： C12N15/09 , C12N9/12
摘要： PROBLEM TO BE SOLVED: To provide a high-polymerization oligosaccharide-forming kojibiose phosphorylase, and to provide a method for producing the same. SOLUTION: The problem is solved as follows: the novel enzyme has the ability to produce a koji oligosaccharide having higher polymerization than that of a wild type kojibiose phosphorylase; the method for producing the enzyme comprises culturing a DNA encoding the enzyme and a microorganism producing the enzyme in a nutrient culture medium and collecting the produced enzyme from the resultant cultured product. COPYRIGHT: (C)2004,JPO

45. 发明专利

JP2013006773A Prophylactic and/or ameliorating agent for insulin resistance 审中-公开
标题翻译：用于胰岛素抵抗的预防和/或调理剂
公开(公告)号：JP2013006773A
公开(公告)日：2013-01-10
申请号：JP2011129982
申请日：2011-06-10
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： ARAI CHIKAKO , SHIBUYA TAKASHI , FUKUDA SHIGEHARU , MIYAKE TOSHIO
IPC分类号： A61K31/7016 , A23L1/30 , A61K47/22 , A61K47/26 , A61K47/42 , A61K47/46 , A61P3/08
CPC分类号： A61K31/7016 , A23L27/33 , A23L33/10 , C07H3/04
摘要： PROBLEM TO BE SOLVED: To provide a prophylactic and/or ameliorating agent for insulin resistance, particularly, the prpphylactic and/or ameliorating agent for insulin resistance which can prevent and/or ameliorate insulin resistance induced by high-fat foods or feeds.SOLUTION: There is provided the prophylactic and/or ameliorating agent for insulin resistance containing α,α-trehalose as an active ingredient, particularly, the prophylactic and/or ameliorating agent for insulin resistance containing α,α-trehalose as an active ingredient and able to prevent and/or ameliorate insulin resistance induced by high-fat foods or feeds.
摘要翻译：要解决的问题：提供用于胰岛素抵抗的预防和/或改善剂，特别是胰岛素抵抗的预防和/或改善剂，其可以预防和/或改善由高脂肪食物或饲料引起的胰岛素抵抗。提供了包含α，α-海藻糖作为活性成分的胰岛素抵抗的预防和/或改善剂，特别是含有α，α-海藻糖作为活性成分的用于胰岛素抵抗的预防和/或改善剂能够预防和/或改善由高脂肪食物或饲料引起的胰岛素抵抗。版权所有（C）2013，JPO＆INPIT

46. 发明专利

JP2012221937A Lighting device with led as light source 审中-公开
标题翻译： LED作为光源的照明设备
公开(公告)号：JP2012221937A
公开(公告)日：2012-11-12
申请号：JP2011096534
申请日：2011-04-07
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： MIYAKE TOSHIO , FUKUDA SHIGEHARU
IPC分类号： F21S6/00 , F21S2/00 , F21V9/16 , F21Y101/02 , H05B37/02
摘要： PROBLEM TO BE SOLVED: To restrain degradation of recognition and judgment of a human being due to fatigue of eye or sense of hearing, with the use of a white-color LED light source.SOLUTION: The lighting device has as a light source a white-color-light LED package consisting of blue-color LED elements, and phosphors emitting fluorescence of a wavelength longer than that of the blue-color LED elements, arranged at an emission side of light of those LED elements, and has a convergent lens arranged at an emission side of light of the white-color-light LED package. The device irradiates light that has a first peak originated in the blue-color LEDs from 420 nm to 450 nm, and a broad second peak from 600 nm to 680 nm, and at the same time, has a shoulder part formed within the range of 480 nm to 500 nm, not substantially increasing changes at appearance and disappearance of visual induction potential of a human being (F-VEP P100 wave) and/or delay of auditory induction potential (P 300 wave).
摘要翻译：要解决的问题：通过使用白色LED光源来抑制由于眼睛疲劳或听觉引起的人的识别和判断的劣化。解决方案：照明装置具有作为光源的由蓝色LED元件组成的白色光LED封装，以及发射比蓝色LED元件的波长更长的荧光的荧光体，布置在这些LED元件的光的发射侧，并且具有配置在白色光LED封装的光的发射侧的会聚透镜。该装置将来自蓝色LED的第一峰的光从420nm至450nm照射，并且从600nm至680nm照射宽的第二峰，并且同时具有形成在 480nm至500nm，人的视觉诱导电位（F-VEP P100波）和/或听觉感应电位的延迟（P 300波）的出现和消失的程度基本上不增加。版权所有（C）2013，JPO＆INPIT

47. 发明专利

JP2011078426A BRANCHED α-GLUCAN, α-GLUCOSYL TRANSFERASE FOR PRODUCING THE SAME, AND MANUFACTURING METHOD AND USE THEREFOR 有权
标题翻译：分支的α-GLUCAN，用于生产α-葡聚糖的α-葡萄糖转移酶及其制备方法和用途
公开(公告)号：JP2011078426A
公开(公告)日：2011-04-21
申请号：JP2010262148
申请日：2010-11-25
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： WATANABE HIKARU , YAMAMOTO TAKUO , NISHIMOTO TOMOYUKI , TSUZAKI KEIJI , OKU KAZUYUKI , CHAEN HIROTO , FUKUDA SHIGEHARU
IPC分类号： A23L1/308 , C12N9/10 , C12P19/18
CPC分类号： A23L33/21 , A21D2/18 , A23C9/1307 , A23C9/1544 , A23L2/39 , A23L9/20 , A23L11/05 , A23L29/35 , A23L33/10 , A23L33/18 , A23V2002/00 , A61K8/73 , A61K8/732 , A61K9/06 , A61K9/20 , A61K31/716 , A61K31/718 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , C08B37/0009 , C12N9/1051 , C12P19/04 , C12P19/18 , C12R1/06 , C12R1/09 , Y02P20/52 , A23V2250/5118 , A23V2200/3262 , A23V2200/328
摘要： PROBLEM TO BE SOLVED: To provide a glucan useful as water-soluble dietary fiber, its preparation and uses. SOLUTION: There is provided a branched α-glucan which is an α-glucan making glucose as a constitution sugar and has a branched structure with a glucose polymerization degree of 1 or more connected to at least non-reduction terminal glucose residue positioned at an end of a linear glucan with a glucose polymerization degree of 3 or more connected through an α-1,4 bond through a bond other than the α-1,4 bond. A new α-glucosyl transferase for producing the branched α-glucan, and a process and use of the same. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供可用作水溶性膳食纤维的葡聚糖及其制备和用途。解决方案：提供一种支链α-葡聚糖，其是制备葡萄糖作为构成糖的α-葡聚糖，并且具有葡萄糖聚合度为1以上的支链结构，至少连接至非还原末端葡萄糖残基在通过α-1,4键通过除了α-1,4键之外的键连接葡萄糖聚合度为3以上的线型葡聚糖的末端。用于生产支链α-葡聚糖的新的α-葡糖基转移酶及其用途及其用途。版权所有（C）2011，JPO＆INPIT

48. 发明专利

JP2010202884A BRANCHED α-GLUCAN, α-GLUCOSYL TRANSFERASE FOR PRODUCING THE SAME, MANUFACTURING METHOD AND USE THEREFOR 有权
公开(公告)号：JP2010202884A
公开(公告)日：2010-09-16
申请号：JP2010132735
申请日：2010-06-10
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： WATANABE HIKARU , YAMAMOTO TAKUO , NISHIMOTO TOMOYUKI , TSUZAKI KEIJI , OKU KAZUYUKI , CHAEN HIROTO , FUKUDA SHIGEHARU
IPC分类号： C08B37/00 , C12P19/18
CPC分类号： A23L33/21 , A21D2/18 , A23C9/1307 , A23C9/1544 , A23L2/39 , A23L9/20 , A23L11/05 , A23L29/35 , A23L33/10 , A23L33/18 , A23V2002/00 , A61K8/73 , A61K8/732 , A61K9/06 , A61K9/20 , A61K31/716 , A61K31/718 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , C08B37/0009 , C12N9/1051 , C12P19/04 , C12P19/18 , C12R1/06 , C12R1/09 , Y02P20/52 , A23V2250/5118 , A23V2200/3262 , A23V2200/328
摘要： PROBLEM TO BE SOLVED: To provide glucan useful as a water-soluble dietary fiber, manufacturing methods and use therefor. SOLUTION: The branched α-glucan is an α-glucan making glucose as a constitution sugar and has a branched structure with a glucose polymerization degree of 1 or more connected to at least non-reduction terminal end in a linear glucan with a glucose polymerization degree of 3 or more connected through an α-1,4 bond through a bond other than the α-1,4 bond, specifically is the branched α-glucan having the following characteristic in methylation analysis. The branched α-glucan characterized in that (1) a ratio of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol is in a range of 1:0.6 to 1:4, (2) a total of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol occupies 60% or more of a partially methylated glucitolacetate, (3) 2,4,6-trimethyl-1,3,5-triacetylglucitol is ≥0.5% and COPYRIGHT: (C)2010,JPO&INPIT

49. 发明专利

JP2010202883A BRANCHED α-GLUCAN, α-GLUCOSYL TRANSFERASE FOR PRODUCING THE SAME, MANUFACTURING METHOD AND USE THEREFOR 审中-公开
标题翻译：分支的α-GLUCAN，用于生产其的α-葡萄糖转移酶，制造方法和用途
公开(公告)号：JP2010202883A
公开(公告)日：2010-09-16
申请号：JP2010132717
申请日：2010-06-10
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： WATANABE HIKARU , YAMAMOTO TAKUO , NISHIMOTO TOMOYUKI , TSUZAKI KEIJI , OKU KAZUYUKI , CHAEN HIROTO , FUKUDA SHIGEHARU
IPC分类号： C08B37/00 , A23L1/22 , A23L1/308 , A61K47/36 , C12P19/16 , C12P19/18
CPC分类号： A23L33/21 , A21D2/18 , A23C9/1307 , A23C9/1544 , A23L2/39 , A23L9/20 , A23L11/05 , A23L29/35 , A23L33/10 , A23L33/18 , A23V2002/00 , A61K8/73 , A61K8/732 , A61K9/06 , A61K9/20 , A61K31/716 , A61K31/718 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , C08B37/0009 , C12N9/1051 , C12P19/04 , C12P19/18 , C12R1/06 , C12R1/09 , Y02P20/52 , A23V2250/5118 , A23V2200/3262 , A23V2200/328
摘要： PROBLEM TO BE SOLVED: To provide glucan useful as a water-soluble dietary fiber, manufacturing methods and use therefor.
SOLUTION: The branched α-glucan is an α-glucan making glucose as a constitution sugar and has a branched structure with a glucose polymerization degree of 1 or more connected to at least non-reduction terminal end in a linear glucan with a glucose polymerization degree of 3 or more connected through an α-1,4 bond through a bond other than the α-1,4 bond, specifically is the branched α-glucan having the following characteristic in methylation analysis. The branched α-glucan characterized in that (1) a ratio of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol is in a range of 1:0.6 to 1:4, (2) a total of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol occupies 60% or more of a partially methylated glucitolacetate, (3) 2,4,6-trimethyl-1,3,5-triacetylglucitol is ≥0.5% and
摘要翻译：要解决的问题：提供可用作水溶性膳食纤维的葡聚糖，其制备方法和用途。解决方案：支链α-葡聚糖是制备葡萄糖作为构成糖的α-葡聚糖，并且具有葡萄糖聚合度为1以上的支链结构，其连接至线性葡聚糖中的至少非还原末端，其中具有特别是在甲基化分析中具有以下特征的支链α-葡聚糖，通过α-1,4键通过α-1,4键以外的键连接3个以上的葡萄糖聚合度。支链α-葡聚糖，其特征在于（1）2,3,6-三甲基-1,4,5-三乙酰基葡萄糖醇与2,3,4-三甲基-1,5,6-三乙酰基葡萄糖醇的比例在 1：0.6〜1：4，（2）总共2,3,6-三甲基-1,4,5-三乙酰基葡萄糖醇和2,3,4-三甲基-1,5,6-三乙酰葡萄糖醇占60％以上的部分甲基化葡萄糖醇乙酸酯，（3）2,4,6-三甲基-1,3,5-三乙酰基葡萄糖醇的部分甲基化葡萄糖醇乙酸酯的含量为≥0.5％和<10％，（4）2,4-二甲基-1,2-二 3,5,6-四乙酰基葡萄糖醇是部分甲基化葡萄糖醇乙酸盐的0.5％以上，用于制造支链α-葡聚糖的新的α-葡糖基转移酶，其制造方法和用途。版权所有（C）2010，JPO＆INPIT

50. 发明专利

JP2010195830A Cyclic maltosyl maltose, cyclic maltosyl maltose synthase, method of producing the same and use thereof 有权
标题翻译：环状麦芽糖醇，周期性麦芽糖醇合成酶，其生产方法及其用途
公开(公告)号：JP2010195830A
公开(公告)日：2010-09-09
申请号：JP2010127390
申请日：2010-06-03
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： MUKAI KAZUHISA , WATANABE HIKARI , NISHIMOTO TOMOYUKI , KUBOTA MICHIO , FUKUDA SHIGEHARU , MIYAKE TOSHIO
IPC分类号： C07H3/06 , A23L1/236 , C12N9/00 , C12N15/09 , C12P19/14
CPC分类号： Y02P20/52
摘要： PROBLEM TO BE SOLVED: To provide a new nonreducing saccharide having glucose as a constituting sugar to broaden a selection range of nonreducing saccharides, a new enzyme for synthesizing the nonreducing saccharide, a method of synthesizing the saccharide, a method of producing the enzyme, a DNA encoding the enzyme, a recombinant DNA and a transformant containing the DNA, a composition containing the above nonreducing saccharide and use of the composition. SOLUTION: There are provided the new nonreducing saccharide having a structure of cycloä→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→}, namely, cyclic maltosyl maltose; a new cyclic maltosyl maltose synthase for synthesizing the saccharide; a method of synthesizing the saccharide; a method of producing the enzyme; a DNA encoding the enzyme; a recombinant DNA and a transformant containing the DNA; a composition containing the cyclic maltosyl maltose or a saccharide containing the cyclic maltosyl maltose; and use of the composition. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种具有葡萄糖作为构成糖的新的非还原糖，以扩大非还原糖的选择范围，用于合成非还原性糖的新酶，合成糖的方法，制备糖的方法酶，编码酶的DNA，重组DNA和含有DNA的转化体，含有上述非还原糖的组合物和组合物的用途。提供了具有cycloa→6）-α-D-吡喃葡萄糖基 - （1→4）-α-D-吡喃葡萄糖基 - （1→6）-α-D-吡喃葡萄糖基的结构的新的非还原性糖 - （1→4）-α-D-吡喃葡萄糖基 - （1→），即环状麦芽糖基麦芽糖;用于合成糖的新的环状麦芽糖基麦芽糖合酶;合成糖的方法;制备该酶的方法编码该酶的DNA;重组DNA和含有该DNA的转化体;含有环状麦芽糖基麦芽糖的组合物或含有该环状麦芽糖基麦芽糖的糖类;以及该组合物的使用。（C）2010，JPO＆INPIT

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