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41. 发明申请

US20060109426A1 Projector with automatic focusing assistance 有权
公开(公告)号：US20060109426A1
公开(公告)日：2006-05-25
申请号：US10997346
申请日：2004-11-23
申请人： David Williams
发明人： David Williams
IPC分类号： G03B21/14
CPC分类号： H04N9/317 , H04N5/74
摘要： A projector with automatic focusing assistance includes a focus control for controlling the focus of optics of the projector, and a focus control use sensor. The projector automatically displays a focus assistance element when the focus control use sensor detects use of the focus control. A method of operating a projector includes automatically displaying a focus assistance element when a focus control of the projector is used.

42. 发明申请

US20060100299A1 Transformable pressure sensitive adhesive tape and use thereof in display screens 审中-公开
标题翻译：可变形压敏胶带及其在显示屏幕中的应用
公开(公告)号：US20060100299A1
公开(公告)日：2006-05-11
申请号：US10522149
申请日：2003-07-18
申请人： Ranjit Malik , Brian Harkins , David Williams
发明人： Ranjit Malik , Brian Harkins , David Williams
IPC分类号： C08G59/68 , B29C71/04
CPC分类号： C08G59/18 , C09J163/00 , G02F1/1339 , G02F1/161 , H01J2211/48 , H01L23/293 , H01L51/5246 , H01L51/5259 , H01L2924/0002 , H01L2924/12044 , H01L2924/00
摘要： A transformable pressure sensitive adhesive composition comprised of from about 15 to about 80% by weight of a polymer having a softening point greater than 60° C.; from about 20 to about 85% by weight of a polymerizable resin having a softening point less than 30° C.; a latent initiator in an amount sufficient to cause a reaction between said polymer and said resin; and optionally, a crosslinking agent. The transformable pressure sensitive adhesive has particular applicability in connection with organic light emitting diode display devices, light emitting diode display devices, medical diagnostic testing devices, flexible or rigid LCD display devices, plasma display devices, and electrochromic devices.
摘要翻译：一种可变形的压敏粘合剂组合物，其由约15至约80重量％的软化点大于60℃的聚合物组成。约20至约85重量％的软化点小于30℃的可聚合树脂; 潜在引发剂，其量足以引起所述聚合物和所述树脂之间的反应; 和任选的交联剂。可变形压敏粘合剂在有机发光二极管显示装置，发光二极管显示装置，医疗诊断测试装置，柔性或刚性LCD显示装置，等离子体显示装置和电致变色装置方面具有特别的适用性。

43. 发明申请

US20060057006A1 Pump assembly 有权
标题翻译：泵总成
公开(公告)号：US20060057006A1
公开(公告)日：2006-03-16
申请号：US11220831
申请日：2005-09-07
申请人： David Williams , David Black , Raymond Johnson , Christopher Sadler , Tim Buttery
发明人： David Williams , David Black , Raymond Johnson , Christopher Sadler , Tim Buttery
IPC分类号： F04B17/00 , F04B35/04
CPC分类号： F04D13/0633
摘要： A pump assembly including a pumping element mounted for rotation within a pump chamber, movement of the pumping element in the chamber causing pumping of fluid within the pump chamber, and a motor, the motor including a stator and a rotor which is connected to the pumping element such that activation of the motor causes movement of the pumping element and hence pumping of fluid within the pump chamber, there being a sealing assembly which permits fluid in the pumping chamber to flow around the rotor but which substantially prevents fluid from the pumping chamber from contacting the stator, the sealing assembly including a partition part which lies between the stator and the pumping chamber and a sealing part which lies between the stator and the rotor, wherein the sealing part is made from a polymeric material over-moulded onto the partition part.
摘要翻译：一种泵组件，其包括被安装用于在泵室内旋转的泵送元件，所述泵室中泵送元件的运动引起泵室内的流体泵送;以及马达，所述马达包括定子和转子，所述定子和转子连接到泵使得电动机的激活导致泵送元件的移动并且因此泵送泵室内的流体，存在允许泵送室中的流体绕转子流动但是基本上防止来自泵送室的流体的密封组件所述密封组件包括位于所述定子和所述泵送室之间的分隔部件和位于所述定子和所述转子之间的密封部件，其中，所述密封部件由覆盖在所述分隔部件上的聚合材料制成，。

44. 发明申请

US20060036087A1 2'-deoxy-2'-fluoro modified RNA 审中-公开
标题翻译： 2'-脱氧-2'-氟修饰的RNA
公开(公告)号：US20060036087A1
公开(公告)日：2006-02-16
申请号：US10656270
申请日：2003-09-05
申请人： Fritz Eckstein , Wolfgang Pieken , Fritz Benseler , David Olsen , David Williams , Olaf Heindenreich
发明人： Fritz Eckstein , Wolfgang Pieken , Fritz Benseler , David Olsen , David Williams , Olaf Heindenreich
IPC分类号： C07H21/02
CPC分类号： C07H21/02 , B65G47/846
摘要： The present invention refers to an RNA molecule with catalytic activity comprising at least one modified nucleoside, wherein the hydroxy group at the 2′-position of the ribose sugar is replaced by a modifier group, selected from halo, sulfhydryl, azido, amino, monosubstituted amino and disubstituted amino groups, a process for the preparation of modified RNA molecules and the use of modified RNA molecules as therapeutic agents and biocatalysts.
摘要翻译：本发明涉及具有至少一种修饰核苷的催化活性的RNA分子，其中核糖2'-位的羟基被选自卤素，巯基，叠氮基，氨基，单取代的修饰基团氨基和二取代的氨基，制备修饰的RNA分子的方法和使用修饰的RNA分子作为治疗剂和生物催化剂。

45. 发明申请

US20050277701A1 Process for making polyurethane and polyisocyanurate foams using mixtures of a hydrofluorocarbon and methyl formate as a blowing agent 审中-公开
标题翻译：使用氢氟烃和甲酸甲酯的混合物作为发泡剂制备聚氨酯和聚异氰脲酸酯泡沫的方法
公开(公告)号：US20050277701A1
公开(公告)日：2005-12-15
申请号：US10868400
申请日：2004-06-15
申请人： Zhen Zhu , David Williams , Mary Bogdan
发明人： Zhen Zhu , David Williams , Mary Bogdan
IPC分类号： C08J9/00 , C08J9/14 , B01F3/04
CPC分类号： C08J9/149 , C08J2203/12 , C08J2203/142 , C08J2375/04
摘要： A process for preparing polyurethane or polyisocyanurate foam by reacting and foaming a mixture of a polyol, and an isocyanate in the presence of a blowing agent which comprises: i) 22 to 78 mole percent of a hydrofluorocarbon; ii) 22 to 78 mole percent of methyl formate; and iii) 0 to 56 mole percent water.
摘要翻译：一种通过在发泡剂存在下使多元醇和异氰酸酯的混合物反应和发泡来制备聚氨酯或聚异氰脲酸酯泡沫的方法，该方法包括：i）22-78摩尔％的氢氟烃; ii）22至78摩尔％的甲酸甲酯; 和iii）0至56摩尔％的水。

46. 发明申请

US20050277567A1 Packaged fibrous toilette article and process 失效
标题翻译：包装纤维香水制品和工艺
公开(公告)号：US20050277567A1
公开(公告)日：2005-12-15
申请号：US11000633
申请日：2004-12-01
申请人： Filomena Macedo , Gregory Grissett , Diane Keenan , David Williams , Michael Clarke
发明人： Filomena Macedo , Gregory Grissett , Diane Keenan , David Williams , Michael Clarke
IPC分类号： A47K5/05 , C11D17/00 , C11D17/04 , A61K7/50
CPC分类号： C11D17/041 , C11D17/0047 , C11D17/006 , C11D17/048
摘要： A cleansing article and process for manufacture is provided, the article being a solid or semi-solid foamable composition joinably penetrating a fibrous web, the combination being molded and held for sale to consumers in a single use disposable sealed plastic receptacle. The receptacle includes indicia printed onto or associated with the plastic receptacle.
摘要翻译：提供了一种清洁用品和制造方法，该制品是固体或半固体可发泡组合物，其可连续地穿透纤维幅材，该组合被模制并保持在一次性一次性密封塑料容器中销售给消费者。容器包括印刷在塑料容器上或与塑料容器相关联的标记。

47. 发明申请

US20050277566A1 Fibrous toilette article 失效
标题翻译：纤维制品
公开(公告)号：US20050277566A1
公开(公告)日：2005-12-15
申请号：US10938384
申请日：2004-09-09
申请人： Gregory Grissett , Diane Keenan , Filomena Macedo , David Williams
发明人： Gregory Grissett , Diane Keenan , Filomena Macedo , David Williams
IPC分类号： A61Q19/10 , C11D17/00 , C11D17/04
CPC分类号： C11D17/041
摘要： A cleansing article is provided which includes a fibrous web of continuous network bonded fibers and a solid or semi-solid foamable composition joinably penetrating the web. The web has a first and second major surface each being on opposite faces of the web. The composition and web are present in a relative weight ratio ranging from about 30:1 to about 2000:1. At least a major portion of the first major surface of the web preferably being exposed above the foamable composition, and a majority of surfaces defining an exterior of the article are formed of the foamable composition.
摘要翻译：提供了一种清洁用品，其包括连续网状粘合纤维的纤维网和可连续地穿透网的固体或半固体可发泡组合物。幅材具有第一和第二主表面，每个表面在幅材的相对面上。组合物和纤维网以约30:1至约2000:1的相对重量比存在。纤维网的第一主表面的至少主要部分优选暴露在可发泡组合物上方，并且限定制品外部的大部分表面由可发泡组合物形成。

48. 发明申请

US20050177624A1 Distributed System and Methodology for Delivery of Media Content to Clients having Peer-to-peer Connectivity 审中-公开
标题翻译：用于将媒体内容传送到具有对等连接的客户端的分布式系统和方法
公开(公告)号：US20050177624A1
公开(公告)日：2005-08-11
申请号：US10709392
申请日：2004-04-30
申请人： Jack Oswald , David Williams
发明人： Jack Oswald , David Williams
IPC分类号： G06F15/16 , H04L29/08
CPC分类号： H04L67/104 , H04L67/1063 , H04L67/1091 , H04L67/322
摘要： A distributed system and methodology for delivery of media content to clients having peer-to-peer connectivity is described. In one embodiment, for example, a method of the present invention is described for distributing media comprises: receiving at a server a request from a first client for a particular media item, the first client having broadband connectivity to other clients; at the server, determining a second client who has an encrypted copy of the desired media item; transferring the encrypted copy of the desired media item from the second client to the first client; after the encrypted copy has been transferred to the first client, indicating at the first client that the desired media item is now available; and in response to receiving payment authorization from the first client, decrypting the desired media item for use at the first client.
摘要翻译：描述了用于向具有点对点连接的客户端传送媒体内容的分布式系统和方法。在一个实施例中，例如，描述了用于分发媒体的本发明的方法，包括：在服务器处接收来自特定媒体项目的第一客户端的请求，所述第一客户端具有到其他客户端的宽带连接; 在服务器处，确定具有所需媒体项目的加密副本的第二客户端; 将所需媒体项目的加密副本从第二客户端传送到第一客户端; 在加密的副本已被传送到第一客户端之后，在第一客户端指示所需的媒体项现在可用; 并且响应于从第一客户端接收到支付授权，对第一客户端使用的所需媒体项进行解密。

49. 发明申请

US20050069553A1 Chimeric peptides for the regulation of GTPases 审中-公开
标题翻译：嵌合肽用于调节GTP酶
公开(公告)号：US20050069553A1
公开(公告)日：2005-03-31
申请号：US10918648
申请日：2004-08-12
申请人： Yi Zheng , David Williams
发明人： Yi Zheng , David Williams
IPC分类号： C07K14/47 , C12N9/14 , A61K39/395 , C07K16/44
CPC分类号： C07K14/4706 , C07K2319/01 , C07K2319/02 , C07K2319/03 , C12N9/14 , C12Y306/05002
摘要： Chimeric peptides or fusion proteins are disclosed that include a RhoGAP activity domain and at least one specificity domain that targets a specific Rho protein. The fusion proteins can be used to inhibit any GTPase activity within a cell. The fusion proteins are particularly advantageous for the treatment of cancer. The present invention generally relates to The present invention generally relates to chimeric peptides capable of regulating GTPases, and more particularly, to methods of targeting individual GTPases by using GTPase-activating proteins. Such proteins may be used for the treatment of cancers and other GTPase-related diseases. This invention relates to nucleic acid molecules and the encoded GTPase activating proteins, and variants thereof, and to the use of these molecules in the characterization, diagnosis, prevention, and treatment of cell signaling, immune, and cell proliferative disorders, particularly cancer. Disclosed herein are compounds and methods for regulating transcription of a selected gene. Methods are provided for constructing and for using such compounds to regulate transcription of a selected gene.
摘要翻译：公开了嵌合肽或融合蛋白，其包括RhoGAP活性结构域和至少一个靶向特异性Rho蛋白的特异性结构域。融合蛋白可用于抑制细胞内的任何GTP酶活性。融合蛋白对癌症的治疗特别有利。本发明一般涉及本发明一般涉及能够调节GTP酶的嵌合肽，更具体地，涉及通过使用GTP酶活化蛋白靶向各个GTP酶的方法。这些蛋白质可用于治疗癌症和其它与GTP酶有关的疾病。本发明涉及核酸分子和编码的GTP酶活化蛋白及其变体，以及这些分子在表征，诊断，预防和治疗细胞信号传导，免疫和细胞增殖性疾病，特别是癌症中的用途。本文公开了用于调节所选基因转录的化合物和方法。提供了构建和使用这些化合物调节所选基因转录的方法。

50. 发明申请

US20050033950A1 Common feature mode for microprocessors in a multiple microprocessor system 有权
标题翻译：多处理器系统中微处理器的通用特征模式
公开(公告)号：US20050033950A1
公开(公告)日：2005-02-10
申请号：US10940394
申请日：2004-09-13
申请人： Valerie See , David Williams
发明人： Valerie See , David Williams
IPC分类号： G06F1/24 , G06F9/00 , G06F9/30 , G06F9/445
CPC分类号： G06F9/30003 , G06F8/61 , G06F8/64 , G06F9/4405
摘要： A mechanism whereby a set of microprocessors may be set to a common mode in which the microprocessors utilize one or more features that are common to all microprocessors. The common mode facilitates proper multiprocessor operation and permits a fix (e.g., a microcode patch) to be applied to each of the microprocessors based on this common mode. More particularly, at system startup, firmware or software can detect whether microprocessors are set to run in different modes (e.g., steppings) in a multiprocessor system. If not, the microprocessors are allowed to run in their normal mode, such as by writing a particular value (e.g., zero) to a configuration register associated with each microprocessor. If features are mixed, a different value can be written, (e.g., one), which tells each microprocessor to revert to a common mode of operation for that family of microprocessors, such as corresponding to a common stepping and/or clock speed. A common set of microcode patches may be downloaded to the microprocessors. Alternatively, the various microprocessors may also be instructed to run in a particular mode that emulates a particular stepping, e.g., by writing into the configuration register or registers a number between one and M that corresponds to a common stepping among the microprocessors.
摘要翻译：可以将一组微处理器设置为微处理器利用所有微处理器所共有的一个或多个特征的共同模式的机制。该共同模式有助于适当的多处理器操作，并且允许基于该共同模式将修复（例如，微代码补丁）应用于每个微处理器。更具体地，在系统启动时，固件或软件可以检测微处理器是否被设置为在多处理器系统中以不同的模式（例如，步进）运行。如果不是，则允许微处理器以其正常模式运行，例如通过将特定值（例如，零）写入与每个微处理器相关联的配置寄存器。如果特征是混合的，则可以写出不同的值（例如一个），其告知每个微处理器恢复到该系列微处理器的公共操作模式，例如对应于公共的步进和/或时钟速度。可以将一组通用的微代码补丁下载到微处理器。或者，也可以指示各种微处理器以模拟特定步进的特定模式运行，例如通过写入配置寄存器或者在与微处理器之间的公共步进相对应的一与M之间登记一个数字。

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