专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

US20140343673A1 Extracellular Matrix Encasement Structures and Methods 有权
标题翻译：细胞外基质包膜结构与方法
公开(公告)号：US20140343673A1
公开(公告)日：2014-11-20
申请号：US13896424
申请日：2013-05-17
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61L31/00 , A61L31/16
CPC分类号： A61L27/3629 , A61F2/0077 , A61F2/02 , A61F2/24 , A61F2002/0086 , A61F2210/0076 , A61K35/12 , A61K35/22 , A61K35/37 , A61K35/38 , A61K35/42 , A61K38/005 , A61K38/1825 , A61L27/227 , A61L27/34 , A61L27/3604 , A61L27/362 , A61L27/3625 , A61L27/3633 , A61L27/3679 , A61L27/3683 , A61L27/38 , A61L27/3804 , A61L27/3834 , A61L27/50 , A61L27/54 , A61L31/005 , A61L31/041 , A61L31/14 , A61L31/16 , A61L2300/20 , A61L2300/23 , A61L2300/25 , A61L2300/252 , A61L2300/40 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/412 , A61L2300/414 , A61L2300/418 , A61L2300/434 , A61L2300/45 , A61L2300/64 , A61L2400/02 , A61L2400/12 , A61L2400/18 , A61L2430/20 , A61N1/375 , A61N1/3752
摘要： A remodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region and at least one lead conduit, the internal region being configured to receive a device therein, the lead conduit being configures to receive at least one device lead therein, the bioremodelable material comprising an extracellular matrix (ECM) composition that includes an ECM component derived from a mammalian source.
摘要翻译：一种可重塑的包装结构，包括由至少一片生物可重塑材料形成的袋，所述袋包括内部区域和至少一个引线导管，所述内部区域被配置为在其中容纳装置，所述引线导管配置为至少接收所述生物可重塑材料包含细胞外基质（ECM）组合物，其包含源自哺乳动物来源的ECM组分。

42. 发明申请

US20140336124A1 Compositions for Regenerating Defective or Absent Myocardium 审中-公开
标题翻译：用于再生缺损或缺血心肌的组合物
公开(公告)号：US20140336124A1
公开(公告)日：2014-11-13
申请号：US14337460
申请日：2014-07-22
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61K38/39
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Injectable collagen based graft compositions and grafts formed from the compositions for tissue regeneration. The compositions and grafts further include a glycosaminoglycan (GAG) to control matrix formation and remodeling.
摘要翻译：可注射的基于胶原的移植组合物和由用于组织再生的组合物形成的移植物。组合物和移植物还包括用于控制基质形成和重塑的糖胺聚糖（GAG）。

43. 发明申请

US20140242183A1 Compositions for Regenerating Defective or Absent Myocardium 审中-公开
公开(公告)号：US20140242183A1
公开(公告)日：2014-08-28
申请号：US14269414
申请日：2014-05-05
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61K35/407 , A61K35/38 , A61K35/37
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.

44. 发明申请

US20140205565A1 Compositions and Methods for Treating Organ Dysfunction 有权
标题翻译：治疗器官功能障碍的组成和方法
公开(公告)号：US20140205565A1
公开(公告)日：2014-07-24
申请号：US14223909
申请日：2014-03-24
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61K38/20 , A61K38/39 , A61K45/06 , A61K38/18 , A61K35/38
CPC分类号： A61L27/3873 , A61K9/0019 , A61K31/22 , A61K31/366 , A61K31/40 , A61K31/4418 , A61K31/505 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/18 , A61K38/1825 , A61K38/1841 , A61K38/20 , A61K38/39 , A61K45/06 , A61K48/00 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/40 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30 , A61K2300/00
摘要： A method of retarding cellular senescence comprising (i) providing an extracellular matrix (ECM) composition comprising ECM from an adolescent tissue source, the ECM comprising an exogenously added cytokine, and (ii) administering ECM composition to an organ with cells exhibiting cellular senescence, wherein, the cytokine interacts with at least one molecule in the ECM composition and modulates ROS production of the cells, whereby, the cellular senescence is abated.
摘要翻译：一种延缓细胞衰老的方法，包括（i）从青少年组织来源提供包含ECM的细胞外基质（ECM）组合物，所述ECM包含外源加入的细胞因子，和（ii）向具有细胞衰老细胞的器官施用ECM组合物，其中，细胞因子与ECM组合物中的至少一个分子相互作用并调节细胞的ROS产生，从而减少细胞衰老。

45. 发明申请

US20140099352A1 Compositions, Structures and Methods for Neural Regeneration 审中-公开
标题翻译：神经再生的组成，结构和方法
公开(公告)号：US20140099352A1
公开(公告)日：2014-04-10
申请号：US14031189
申请日：2013-09-19
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61L27/36 , A61K31/722 , A61L27/54 , A61K35/12
CPC分类号： A61L27/3633 , A61K31/722 , A61K35/12 , A61K45/06 , A61L27/3675 , A61L27/3878 , A61L27/54 , A61L2300/414 , A61L2300/64 , A61L2430/32 , A61K2300/00
摘要： A nerve regeneration device comprising a support structure having an outer surface and a plurality of conduits extending therethrough, the support structure comprising a first extracellular matrix (ECM) material from a mammalian tissue source, the support structure outer layer including at least a first layer comprising a first ECM composition having at least a second ECM material from a mammalian tissue source. When the nerve regeneration device is deployed proximate damaged neural tissue, the device induces modulated healing of the damaged tissue.
摘要翻译：神经再生装置，其包括具有外表面和延伸穿过其中的多个导管的支撑结构，所述支撑结构包括来自哺乳动物组织源的第一细胞外基质（ECM）材料，所述支撑结构外层至少包括第一层，具有来自哺乳动物组织源的至少第二ECM材料的第一ECM组合物。当神经再生装置部署在损伤的神经组织附近时，该装置诱导受损组织的调节愈合。

46. 发明申请

US20130116198A1 Compositions for Regenerating Defective or Absent Myocardium 失效
公开(公告)号：US20130116198A1
公开(公告)日：2013-05-09
申请号：US13732718
申请日：2013-01-02
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61L27/36
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.

47. 发明申请

US20100010627A1 Breast Implants and Compositions of Extracellular Matrix 审中-公开
标题翻译：乳腺植入物和细胞外基质的组成
公开(公告)号：US20100010627A1
公开(公告)日：2010-01-14
申请号：US12428766
申请日：2009-04-23
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61F2/0059 , A61L27/3633 , A61L27/3641 , A61L27/3839
摘要： The invention is articles and compositions of extracellular matrix for forming breast implants and otherwise augmenting or reconstructing breast tissue and other cosmetically desired tissue in humans, such as lips and cheeks. The invention is also to methods of using these in implant articles to augment or reconstruct a human breast or other tissue.
摘要翻译：本发明是用于形成乳房植入物的细胞外基质的制品和组合物，以及另外增加或重建人类乳头组织和其他美容上期望的组织，例如唇和脸颊。本发明还涉及在种植体制品中使用这些方法来增加或重建人乳房或其他组织的方法。

48. 发明申请

US20090157177A1 Sewing Ring for a Prosthetic Tissue Valve 审中-公开
标题翻译：假肢组织瓣缝合环
公开(公告)号：US20090157177A1
公开(公告)日：2009-06-18
申请号：US11958407
申请日：2007-12-18
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61F2/24
CPC分类号： A61F2/2409
摘要： The invention provides a trileaflet semi-lunar prosthetic tissue valve for aortic, pulmonary, mitral, or tricuspid valve replacement. The valve is planar before attachment at an annulus of a valvular lumen, and non-planar upon attachment at the annulus of the defective valve. A sewing ring having a circumference greater than the annular circumference of annulus of the valve being replaced is also described and the sewing ring is placed at the approximate position of the annulus of the defective valve in a non-planar configuration.
摘要翻译：本发明提供了用于主动脉，肺，二尖瓣或三尖瓣置换的三叶片半月板假体组织瓣膜。瓣膜在安装在瓣膜腔的环形处之前是平面的，并且在附着在有缺陷的瓣膜的环上时是非平面的。还描述了具有大于被更换的阀的环形环的周长的缝制环，并且缝合环以非平面构型放置在有缺陷阀的环的近似位置处。

49. 发明申请

US20090142409A1 Extracellular Matrix Compositions for Tissue Regeneration 审中-公开
标题翻译：用于组织再生的细胞外基质组合物
公开(公告)号：US20090142409A1
公开(公告)日：2009-06-04
申请号：US12371158
申请日：2009-02-13
申请人： Leigh H. Firestone , Robert G. Matheny
发明人： Leigh H. Firestone , Robert G. Matheny
IPC分类号： A61K35/38 , A61K35/22 , A61K38/00
CPC分类号： A61K35/34 , A61K35/32 , A61K35/39 , A61K35/42 , A61K35/54 , A61K35/545 , A61K38/00 , A61L27/3633 , A61K2300/00
摘要： The invention is compositions of extracellular matrix that comprise mammalian extracellular matrix from two or more tissue sources in a mammal. The invention also includes methods of using these compositions to regenerate tissue or generate new tissue at sites of defects or wounds in mammals.
摘要翻译：本发明是包含哺乳动物中两种或多种组织来源的哺乳动物细胞外基质的细胞外基质的组合物。本发明还包括使用这些组合物来再生组织或在哺乳动物缺陷或创伤部位产生新组织的方法。

50. 发明授权

US06328757B1 Device and method for performing surgery without impeding organ function 有权
标题翻译：用于进行手术而不阻碍器官功能的装置和方法
公开(公告)号：US06328757B1
公开(公告)日：2001-12-11
申请号：US09298794
申请日：1999-04-23
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61M2900
CPC分类号： A61B17/00234 , A61B17/0293 , A61B2017/00243 , A61B2017/00557
摘要： A method and device for enabling direct visualization and access to a body organ without impeding or stopping the function of the organ is provided. The device includes a balloon catheter, having a balloon at or near its distal end, and a preferably funnel-shaped access member positioned around the catheter. In use, an incision is placed in a patient, and a path is cleared to the organ or tissue on which surgery is to be performed. The catheter is inserted into the organ and to or through the tissue requiring treatment. If the catheter moves through the tissue to be treated, the balloon is inflated to provide a seal preventing fluids from moving through the tissue. The access member is then advanced over the catheter to the tissue site, enabling the surgeon to directly see and access the tissue.
摘要翻译：提供了一种能够直接观察和访问身体器官而不妨碍或停止器官功能的方法和装置。该装置包括气球导管，在其远端处或其近端具有气囊，以及围绕导管定位的优选的漏斗状进入构件。在使用中，将切口放置在患者体内，将路径清除到要进行手术的器官或组织。将导管插入器官并穿过需要治疗的组织。如果导管移动通过要处理的组织，则气囊膨胀以提供防止流体通过组织移动的密封。然后将进入构件在导管上前进到组织部位，使得外科医生能够直接观察和进入组织。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式