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41. 发明申请

WO1997046550A1 THIOPHENE HALIDE DERIVATIVES 审中-公开
标题翻译： HALOGENTHIOPHEN衍生物
公开(公告)号：WO1997046550A1
公开(公告)日：1997-12-11
申请号：PCT/EP1997002623
申请日：1997-05-22
申请人： BAYER AKTIENGESELLSCHAFT , HEINEMANN, Ulrich , DUTZMANN, Stefan
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C07D333/24
CPC分类号： C07D333/24 , C07D333/28
摘要： The invention concerns novel thiophene halide derivatives of formula (I) in which X stands for chlorine, bromine or iodine, R stands for alkyl, and R stands for hydrogen or alkyl. The invention also concerns a process for preparing these derivatives and their use in combating undesirable micro-organisms. The invention finally concerns novel intermediate products of formulae (II) and (III), in which R and R have the above meanings, and processes for preparing these intermediate products.
摘要翻译： Halogenthiophen的式（I），其中X是氯，溴或碘的新的衍生物; [R <1>是烷基并且R <2>是氢或烷基，其制备方法和它们在防治不希望的微生物的用途。式（II）和新的中间体（III），其中R <1>和R <2>具有上面给出的含义，并且制备这些中间体的方法。

42. 发明申请

WO1997045739A1 MASKING BACKGROUND FLUORESCENCE AND LUMINESCENCE IN OPTICAL ANALYSIS OF BIOMEDICAL ASSAYS 审中-公开
标题翻译：面具光学分析生物医学分析的背景和荧光发光
公开(公告)号：WO1997045739A1
公开(公告)日：1997-12-04
申请号：PCT/EP1997002662
申请日：1997-05-23
申请人： BAYER AKTIENGESELLSCHAFT , KRAHN, Thomas , PAFFHAUSEN, Wolfgang , SCHADE, Andreas , BECHEM, Martin , SCHMIDT, Delf
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： G01N33/543
CPC分类号： G01N33/542 , G01N33/5005 , G01N33/5306 , G01N33/54393 , Y10S436/80 , Y10S436/805 , Y10S436/823 , Y10T436/13
摘要： In a procedure for quantitative optical analysis of fluorescently-labelled biological cells (5) a cell layer is appplied to a transparent carrier at the base (2) of a reaction vessel (1) so that it is in contact with the solution (3) containing the fluorescent dye (4). The sensitivity of the determination may be significantly improved by adding to the solution (3) a masking dye (9), which absorbs the exciting light (6) for the fluorescent dye (4) already present in the solution (3) and/or its emitted light (7), and/or by applying an interlayer (10) that is permeable to the solution but absorbs and/or reflects the exciting light (6) or the emitted light (7) to the cell layer at the base (2). The same procedure may be used to improve sensitivity in quantitative optical analysis of a luminescent biological cell layer. In the latter case the interlayer (10) should be composed so that is possesses a high reflection factor with respect to luminescent light (11). Analogously, these procedural principles may also be applied in receptor studies to mask disturbing background radiation in quantitative optical analysis of fluorescently- or luminescently-labelled participants in a reaction. In this case a receptor layer (12) is placed at the base (2) of a reaction vessel (1) in contact with a solution (supernatant 3) in which a fluorescent or luminescent ligand (13) has been dissolved. The sensitivity and accuracy of the determination may be significantly improved if a masking dye (9) which absorbs the exciting light (6) for the fluorescent dye and/or its emitted light or (in case of luminescent ligands) the luminescent light is added to the supernatant (3). An interlayer (10) that is permeable to the solution (3) but absorbs and/or reflects the exciting light (6) and/or the emitted light or the luminescent light may be applied to the cell or receptor layer (12) at the base (2) instead of the masking dye in the solution (3) or possibly as a supplementary measure.
摘要翻译：在用于荧光标记的生物细胞的定量光学分析的方法（5）是细胞的在透明支持体与（4）含有（3）相接触的荧光染料溶液的层在反应容器（1）的底部（2）。分析检测的灵敏度可以如果在除了现有的荧光染料的溶液（3）（4）被加入到一个掩蔽染料（9），该激励光（6）的荧光染料（4）和/或它的发射光被显着地改善（7）吸收及/或时，（6）或发射光（7）的吸收和/或反射的分离层（10）涂布在细胞层的底部（2）渗透到该溶液中的激发光。也可以应用于本方法，以改善发光生物细胞层的定量光学分析的灵敏度。剥离层（10）在此情况下，其具有用于发光的光（11）的高反射率是这样的。以类似的方式，这些方法原理也可以应用到受体的研究以掩蔽干扰背景辐射在荧光或发光标记的反应物的定量光学分析。在这种情况下，它是在一个反应容器（1）的底部（2）与在接触溶液（上清液3），其中，荧光或发光配位体（13）式求得的受体层（12）。分析检测的灵敏度和准确度可能在这种情况下大大提高如果将上清液3是掩蔽染料（9）添加被这为荧光染料和/或它的发射光或激发光（6）吸收发光（在发光配位体的情况下），而不是在溶液（3），或者，如果必要的话，作为一种附加措施的细胞或受体层（12）在底部（2）渗透一种为溶液（3）中，激发光（6）和/或发射光的遮蔽染料的或发光光吸收和/或反射的分离层（10）被应用。

43. 发明申请

WO1997045418A1 SUBSTITUTED PHENYL URACILS 审中-公开
标题翻译：取代苯基尿嘧啶
公开(公告)号：WO1997045418A1
公开(公告)日：1997-12-04
申请号：PCT/EP1997002488
申请日：1997-05-15
申请人： BAYER AKTIENGESELLSCHAFT , DREWES, Mark, Wilhelm , ANDREE, Roland , DOLLINGER, Markus
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C07D239/54
CPC分类号： C07D239/54 , A01N43/54
摘要： New substituted phenyl uracils are described which have general formula (I), whereby R is hydrogen, halogen or optionally substituted alkyl, R is optionally substituted alkyl, R is hydrogen, an amino group or optionally substituted alkyl, alkenyl or alkinyl, R is hydrogen, a cyano group or halogen, R is a cyano group or thiocarbamoyl, R is one of the groups (1), (2), (3), wherein Q and Q are oxygen or sulphur, R is hydrogen or optionally substituted alkyl, R is hydrogen, a hydroxyl group, an amino group or optionally substituted alkyl, alkoxy, alkylamino, dialkylamino, alkylcarbonylamino, alkylsulfonylamino, alkenyl, alkenyloxy, alkinyl, cycloalkyl, cycloalkyloxy, cycloalkylamino, cycloalkylcarbonylamino, cycloalkylsulfonylamino, aryl, aryloxy, arylamino, arylcarbonylamino, arylsulfonylamino, arylalkyl, arylalkoxy or arylalkylamino group, R and R are alkyl. A method for production of said compounds and their use as herbicides are described.
摘要翻译：本发明涉及通式（I）中R <1>是氢，卤素或任选取代的烷基的新的取代的苯基尿嘧啶，R <2>的任选取代的烷基，R <3>表示氢，氨基或在每种情况下任选取代的烷基，烯基或炔基，R <4>是氢，氰基或卤素，R <5>表示氰基或硫代氨基甲酰基，和R <6>是组中的一个（1），（2），（3）是其中Q <1>和Q <2>为氧或硫，R <7>各自代表氢或任选取代的烷基，R <8>代表氢，羟基，氨基，或代表各自任选被取代的烷基，烷氧基，烷基氨基，二烷基氨基，烷基羰基氨基，烷基磺酰基氨基，烯基，烯氧基，炔基，环烷基，环烷基氧基，环烷基氨基，环烷基羰基，cycloalkylsulfonylamino，芳基，芳氧基，芳基氨基，芳基羰基，基磺酰基氨基，芳基烷基，芳基烷氧基，芳基烷基氨基，和R <9>和R <10>是烷基，它们的制备方法和它们作为除草剂的用途。

44. 发明申请

WO1997043275A2 NEW SUBSTITUTED PYRIDYL KETO ENOLS 审中-公开
标题翻译：新的取代PYRIDYLKETOENOLE
公开(公告)号：WO1997043275A2
公开(公告)日：1997-11-20
申请号：PCT/EP1997002183
申请日：1997-04-28
申请人： BAYER AKTIENGESELLSCHAFT , LIEB, Folker , HAGEMANN, Hermann , WIDDIG, Arno , RUTHER, Michael , FISCHER, Reiner , BRETSCHNEIDER, Thomas , ERDELEN, Christoph , WACHENDORFF-NEUMANN, Ulrike , GRAFF, Alan , DAHMEN, Peter , DOLLINGER, Markus , GALLENKAMP, Bernd
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C07D401/04
CPC分类号： C07D401/04 , A01N43/40 , A01N47/06 , C07D213/56 , C07D409/14
摘要： The invention pertains to new pyridyl-substituted cyclic keto enols of formula (I), wherein V , V or V is nitrogen, Het is one of the groups (1), (2), (3), (4) or (5), and A, B, G, W, Z and z are as indicated in the description. The invention also pertains to several methods and intermediates for their preparation as well as their use as pesticides and herbicides.
摘要翻译：本发明涉及式（I）的新的吡啶基取代的环酮 - 烯醇其中V <1>，V <2>或V <3>是氮，Het表示的基团（1）中的一个，（2），（3），（4）或（5）中，A，B，G，W，Z和Z具有说明书中给出的含义，几种方法和中间体及其制备方法和它们作为杀虫剂和除草剂的用途。

45. 发明申请

WO1997043269A1 TRIAZOLYL DISULPHIDES 审中-公开
标题翻译：三唑DISULFIDE
公开(公告)号：WO1997043269A1
公开(公告)日：1997-11-20
申请号：PCT/EP1997002282
申请日：1997-05-05
申请人： BAYER AKTIENGESELLSCHAFT , JAUTELAT, Manfred , DUTZMANN, Stefan , STENZEL, Klaus
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C07D249/12
CPC分类号： C07D401/14 , A01N43/653 , C07D231/12 , C07D233/56 , C07D249/08 , C07D249/12 , C07D405/14 , C07F7/0812
摘要： The invention relates to novel triazolyl disulphides of formula (I), in which R has the meanings given in the description. It also relates to the acid addition salts and metal salt complexes of said triazolyl disulphides, a process for preparing said novel substances and the use thereof as microbicides in plant and material protection.
摘要翻译：式（I），其中R <1>具有在说明书中给出的含义，和它们的酸加成盐和金属盐配合物，用于制备新的物质和它们作为在作物保护和杀微生物剂的使用的处理的新的三唑基二硫化物保护的材料。

46. 发明申请

WO1997041889A1 FELINE VACCINES CONTAINING CHLAMYDIA PSITTACI AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：含有CHLAMYDIA PSITTACI的FELINE疫苗及其制备方法
公开(公告)号：WO1997041889A1
公开(公告)日：1997-11-13
申请号：PCT/US1997007514
申请日：1997-04-21
申请人： BAYER CORPORATION , BAYER AKTIENGESELLSCHAFT
发明人： BAYER CORPORATION , BAYER AKTIENGESELLSCHAFT , ATHERTON, Rebecca, A. , SCHMEER, Norbert , HALLSTROM, Jean, A. , LANE, Jennifer, K. , HENNESSY, Kristina, J.
IPC分类号： A61K39/118
CPC分类号： A61K39/118 , A61K39/12 , A61K39/23 , A61K39/265 , A61K2039/521 , A61K2039/552 , A61K2039/70 , C12N2710/16734 , C12N2740/10034 , C12N2750/14334 , C12N2770/16034
摘要： The present invention relates to feline vaccines comprising inactivated a non reactive Chlamydia psittaci for prevention and treatment of chlamydia diseases in cats.
摘要翻译：本发明涉及用于预防和治疗猫中衣原体疾病的非活性衣原体衣原体灭活的猫科动物疫苗。

47. 发明申请

WO1997036853A1 DIMETHYL-SUBSTITUTED CYCLOHEXANE DIENE DERIVATIVES 审中-公开
标题翻译：二甲基取代CYCLOHEXANDIENDERIVATE
公开(公告)号：WO1997036853A1
公开(公告)日：1997-10-09
申请号：PCT/EP1997001328
申请日：1997-03-17
申请人： BAYER AKTIENGESELLSCHAFT , URBAHNS, Klaus , MAULER, Frank
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C07C69/753
CPC分类号： C07C69/753 , A61K31/215
摘要： The present invention relates to dimethyl-substituted cyclohexane diene derivatives, a process for their production, their use as medicaments and corresponding medicaments.
摘要翻译：本发明涉及二甲基取代Cyclohexandienderivate，它们的制备，它们作为药物的用途以及与其对应的药物的用途。

48. 发明申请

WO1997035899A1 PROCESS FOR PRODUCING HYDROCARBON-BLOWN HARD POLYURETHANE FOAMS 审中-公开
标题翻译：工艺用于制造烃-驱动的硬质聚氨酯泡沫塑料
公开(公告)号：WO1997035899A1
公开(公告)日：1997-10-02
申请号：PCT/EP1997001198
申请日：1997-03-10
申请人： BAYER AKTIENGESELLSCHAFT , DIETRICH, Karl, Werner , EISEN, Norbert , HEILIG, Gerhard
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C08G18/48
CPC分类号： C08J9/141 , C08G18/482 , C08G2101/0025 , C08G2101/005 , C08G2105/02 , C08J2375/04
摘要： The description relates to a process for producing hard urethane and possibly urea and isocyanate-group-containing foams in which a hard polyurethane foam is made by reacting a) an aromatic polyisocyanate with b) a polyol component with an average of at least three hydrogen atoms reactive to isocyanates, containing 1) 30 to 80 wt.% of an aromatic amine-started polyether with a molecular weight of 300 to 800 based on 70 to 100 wt.% 1,2-propylene oxide and 0 to 30 wt.% ethylene oxide, 2) 10 to 40 wt.% of an essentially sucrose-started polyether with a molecular weight of 400 to 1000 based on 70 to 100 wt.% 1,2-propylene oxide and 0 to 30 wt.% ethylene oxide, 3) 5 to 30 wt.% of a propylene glycol-started polyether with a molecular weight from 500 to 1500 based on 70 to 100 wt.% 1,2-propylene oxide and 0 to 30 wt.% ethylene oxide, 4) n and/or i-pentane as the blowing agent, 5) water, 6) possible auxiliaries and additives, where the percentage weights of components 1), 2) and 3) amount to 100.
摘要翻译：公开的是用于生产硬质聚氨酯和任选的脲和异氰脲酸酯泡沫体的方法，其特征在于，硬质聚氨酯泡沫由a）一种异氰酸酯与b）一种异氰酸酯 - 反应性平均至少3个氢原子轴承多元醇反应的芳族，包含：1）30〜80重量％（重量）的芳族胺的开始分子量300的聚醚〜800 70〜100 .- 1,2-氧化丙烯和0％的基础上，以30重量％的环氧乙烷2）10至 40重量〜1000基于70〜100重量的1,2-氧化丙烯的％和0分子量400的基本上蔗糖gestarten聚醚％至30重量的环氧乙烷3）5至30重量份的％丙二醇的％开始分子量500的聚醚至1500基于70〜100重量的1,2-氧化丙烯的％和0至30重量的环氧乙烷4）n和/或异戊烷的％作为发泡剂5）任选的水，6） enfalls助剂和添加剂制备，其中，所述重量部件1％），2）和3）是互补的：100。

49. 发明申请

WO1997030980A1 SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONES AS HERBICIDES 审中-公开
标题翻译：取代的2-芳基-1,2,4-三嗪-3,5-二（THI）的人作为除草剂
公开(公告)号：WO1997030980A1
公开(公告)日：1997-08-28
申请号：PCT/EP1997000610
申请日：1997-02-10
申请人： BAYER AKTIENGESELLSCHAFT , LINKER, Karl-Heinz , FINDEISEN, Kurt , DOLLINGER, Markus , SANTEL, Hans-Joachim
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C07D253/06
CPC分类号： C07D253/075 , A01N43/707
摘要： The invention relates to novel substituted 2-aryl-1,2,4-triazine-3,5-di(thi)ones of the general formula (I) in which R , R , R , R , R , Q and Q have the meanings given in the description, process for their production and their use as herbicides.
摘要翻译：本发明涉及新的取代的2-芳基-1,2,4-三嗪-3,5-二（THI）通式（I）中R <1>，R <2>，R <3>中的一些， [R <4>，R <5>，Q <1>和Q <2>具有说明书中给出的含义，它们的制备方法和它们作为除草剂的用途。

50. 发明申请

WO1997030075A1 OXIME- AND NITRON-SUBSTITUTED PSEUDOPEPTIDES WITH AN ANTI-VIRAL ACTION 审中-公开
标题翻译：抗病毒活性肟和硝基取代的肽伪
公开(公告)号：WO1997030075A1
公开(公告)日：1997-08-21
申请号：PCT/EP1997000470
申请日：1997-02-03
申请人： BAYER AKTIENGESELLSCHAFT , RADDATZ, Siegfried , HÄBICH, Dieter , SCHULZE, Thomas-Joachim , SCHENKE, Thomas , REEFSCHLÄGER, Jürgen
发明人： BAYER AKTIENGESELLSCHAFT
IPC分类号： C07K05/06
CPC分类号： C07K5/06095 , A61K38/00
摘要： The invention concerns oxime- and nitron-substituted pseudopeptides with an anti-viral action and having general formula (I) in which the substituents are as defined in the description. The invention also concerns methods of preparing such pseudopeptides and their use as antiviral agents, in particular against cytomegalviruses.
摘要翻译：本发明涉及新的抗病毒有效肟和通式（I），其中各取代基具有本说明书给出的含义的硝基取代的假肽，它们的制备方法和它们作为抗病毒剂的应用，特别是对巨细胞病毒。

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