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41. 发明申请

US20150190456A1 USE OF CASPASE 3 ACTIVITY AND ITS INHIBITORS 审中-公开
标题翻译：使用CASPASE 3活性及其抑制剂
公开(公告)号：US20150190456A1
公开(公告)日：2015-07-09
申请号：US14128228
申请日：2012-06-20
申请人： Chuan-Yuan Li , Qian Huang , Fang Li
发明人： Chuan-Yuan Li , Qian Huang , Fang Li
IPC分类号： A61K38/00 , G01N33/574 , A61K31/5377 , A61K31/27 , A61K45/06 , A61K31/404
CPC分类号： A61K38/005 , A61K31/10 , A61K31/27 , A61K31/404 , A61K31/5377 , A61K45/06 , G01N33/57407 , G01N33/57415 , G01N33/57419 , G01N33/5743 , G01N2333/96466 , G01N2800/54
摘要： The present invention provides methods for using the level of caspase 3 activity for determining or prognosticating likelihood of cancer recurrence or relapse in a patient after the treatment for cancer. The present invention also provides methods for treating cancer in a patient using a caspase 3 inhibitor in conjunction with a conventional cancer treatment.
摘要翻译：本发明提供使用胱天蛋白酶3活性水平来确定或预测癌症治疗后患者癌症复发或复发的可能性的方法。本发明还提供了结合常规癌症治疗使用胱天蛋白酶3抑制剂治疗患者癌症的方法。

42. 发明申请

US20140211848A1 METHOD AND APPARATUS FOR REDUCTION OF DEBLOCKING FILTER 有权
标题翻译：用于减少阻塞过滤器的方法和装置
公开(公告)号：US20140211848A1
公开(公告)日：2014-07-31
申请号：US14342334
申请日：2012-08-09
申请人： Chih-Wei Hsu , Qian Huang , Jicheng An , Xun Guo , Yu-Wen Huang , Shaw-Min Lei
发明人： Chih-Wei Hsu , Qian Huang , Jicheng An , Xun Guo , Yu-Wen Huang , Shaw-Min Lei
IPC分类号： H04N19/117 , H04N19/82 , H04N19/50
CPC分类号： H04N19/117 , H04N19/14 , H04N19/176 , H04N19/186 , H04N19/50 , H04N19/82 , H04N19/86
摘要： A method and apparatus for deblocking of reconstructed video are disclosed. In one embodiment, the method divides a block boundary into two sub-boundaries and separates lines or column across the sub-boundaries into two groups. The deblocking filter decision for each group is determined based on the lines or columns in the respective group. In another embodiment, the method divides block edges of blocks in the LCUs into two edge groups, where the first edge group corresponds to horizontal block edges between two LCUs and the second edge group corresponds to remaining block edges not included in the first edge group. The number of lines processed by a vertical filter in the first edge group is less than the number of lines processed by a vertical filter in the second edge group. Accordingly, a system embodying the present invention has reduced storage requirement.
摘要翻译：公开了一种重构视频解块的方法和装置。在一个实施例中，该方法将块边界划分为两个子边界，并将跨越子边界的线或列分成两组。基于相应组中的线或列确定每组的去块滤波器决定。在另一个实施例中，该方法将LCU中的块的块边缘划分为两个边缘组，其中第一边缘组对应于两个LCU之间的水平块边缘，并且第二边缘组对应于未包括在第一边缘组中的剩余块边缘。由第一边缘组中的垂直滤波器处理的线数小于由第二边缘组中的垂直滤波器处理的线数。因此，体现本发明的系统减少了存储要求。

43. 发明授权

US08560319B1 Method and apparatus for segmenting a multimedia program based upon audio events 有权
标题翻译：基于音频事件分割多媒体节目的方法和装置
公开(公告)号：US08560319B1
公开(公告)日：2013-10-15
申请号：US12008912
申请日：2008-01-15
申请人： Qian Huang , Zhu Liu
发明人： Qian Huang , Zhu Liu
IPC分类号： G10L15/28
CPC分类号： G10L25/48
摘要： The present invention provides for a method and apparatus for segmenting a multi-media program based upon audio events. In an embodiment a method of classifying an audio stream is provided. This method includes receiving an audio stream. Sampling the audio stream at a predetermined rate and then combining a predetermined number of samples into a clip. A plurality of features are then determined for the clip and are analyzed using a linear approximation algorithm. The clip is then characterized based upon the results of the analysis conducted with the linear approximation algorithm.
摘要翻译：本发明提供一种用于基于音频事件分割多媒体节目的方法和装置。在一个实施例中，提供了对音频流进行分类的方法。该方法包括接收音频流。以预定速率对音频流进行采样，然后将预定数量的样本组合成剪辑。然后为剪辑确定多个特征，并使用线性近似算法进行分析。然后基于使用线性近似算法进行的分析的结果来表征该剪辑。

44. 发明申请

US20130266061A1 Method and Apparatus of Deblocking Filter 有权
标题翻译：去块滤波器的方法和装置
公开(公告)号：US20130266061A1
公开(公告)日：2013-10-10
申请号：US13993063
申请日：2012-03-06
申请人： Jicheng An , Xun Guo , Qian Huang , Shaw-Min Lei
发明人： Jicheng An , Xun Guo , Qian Huang , Shaw-Min Lei
IPC分类号： H04N7/26
CPC分类号： H04N19/117 , H04N19/14 , H04N19/176 , H04N19/86
摘要： A method and apparatus for improved deblocking filter are disclosed. In one embodiment according to the present invention, determining the non-zero transform coefficients existence for a PU-only boundary is skipped and therefore the deblocking filter for PU-only boundary is eliminated if the condition of boundary strength equal to 1 is not fulfilled to avoid unnecessary deblocking. In another embodiment of the present invention, three gradients are determined for two pixel lines and filter ON/OFF decision is made based on the three gradient values of the two pixel lines. One aspect of the invention is related to filter strength selection between strong and weak filters. According to one embodiment, the filter strength selection is based on various gradient values of a pixel line across the block boundary. Another aspect of the invention is related to the weak filter.
摘要翻译：公开了一种改进的去块滤波器的方法和装置。在根据本发明的一个实施例中，对于仅PU边界确定非零变换系数的存在被跳过，因此如果边界强度等于1的条件不满足于仅用于PU的边界的去块滤波器避免不必要的解锁。在本发明的另一实施例中，针对两个像素线确定三个梯度，并且基于两个像素线的三个梯度值来进行滤波器ON / OFF判定。本发明的一个方面涉及强和弱滤波器之间的滤波强度选择。根据一个实施例，滤波器强度选择基于跨越块边界的像素线的各种梯度值。本发明的另一方面涉及弱滤波器。

45. 发明申请

US20090079425A1 Magnetic Sensitivity Measurement System 有权
标题翻译：磁敏度测量系统
公开(公告)号：US20090079425A1
公开(公告)日：2009-03-26
申请号：US11859020
申请日：2007-09-21
申请人： Qian Huang
发明人： Qian Huang
IPC分类号： G01R33/02
CPC分类号： G01R33/07
摘要： A system and method for determining the magnetic sensitivity of a Hall-effect switch through the use of a variable powered DC electromagnet having a permanent magnet attached to it. In use the electromagnet is placed in contact with a Hall-effect switch component and the DC voltage varied until a detector determines the Hall-effect switch has been triggered. The electromagnet is then moved to be in contact with a probe connected to a Gauss meter to determine the magnetic sensitivity of the Hall-effect switch.
摘要翻译：一种用于通过使用具有附接到其上的永磁体的可变动力DC电磁铁来确定霍尔效应开关的磁敏感度的系统和方法。在使用中，电磁体与霍尔效应开关组件接触，直流电压变化，直到检测器确定霍尔效应开关已被触发。然后将电磁铁移动与与高斯计连接的探头接触，以确定霍尔效应开关的磁敏感度。

46. 发明申请

US20070048320A1 Method for indentifying modulators of PPIL2 useful for treating Alzheimer's disease 审中-公开
标题翻译：用于鉴定治疗阿尔茨海默病的PPIL2调节剂的方法
公开(公告)号：US20070048320A1
公开(公告)日：2007-03-01
申请号：US11514737
申请日：2006-08-31
申请人： Amy Espeseth , Daria Hazuda , Peter Linsley , Qian Huang
发明人： Amy Espeseth , Daria Hazuda , Peter Linsley , Qian Huang
IPC分类号： A61K39/395 , G01N33/567 , A61K39/00
CPC分类号： C07K16/18 , A61K2039/505 , C07K16/40 , C12N9/90 , G01N33/6896 , G01N2333/4709 , G01N2500/10
摘要： Methods for identifying modulators of PPIL2 are described. The methods are particularly useful for identifying analytes that antagonize PPIL2's effect on processing of amyloid precursor protein to Aβ peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease.
摘要翻译：描述了用于鉴定PPIL2调节剂的方法。该方法特别适用于鉴定拮抗PPIL2对淀粉样蛋白前体蛋白加工成Abeta肽的影响的分析物，因此可用于鉴定可用于治疗阿尔茨海默病的分析物。

47. 发明授权

US07184959B2 System and method for automated multimedia content indexing and retrieval 有权
标题翻译：用于自动多媒体内容索引和检索的系统和方法
公开(公告)号：US07184959B2
公开(公告)日：2007-02-27
申请号：US10686459
申请日：2003-10-15
申请人： David Crawford Gibbon , Qian Huang , Zhu Liu , Aaron Edward Rosenberg , Behzad Shahraray
发明人： David Crawford Gibbon , Qian Huang , Zhu Liu , Aaron Edward Rosenberg , Behzad Shahraray
IPC分类号： G10L17/00 , G06F17/28 , G06F17/30
CPC分类号： G06F17/30787 , G06F17/30796 , G06F17/30843 , G10L17/00 , Y10S707/99933 , Y10S707/99943
摘要： The invention provides a system and method for automatically indexing and retrieving multimedia content. The method may include separating a multimedia data stream into audio, visual and text components, segmenting the audio, visual and text components based on semantic differences, identifying at least one target speaker using the audio and visual components, identifying a topic of the multimedia event using the segmented text and topic category models, generating a summary of the multimedia event based on the audio, visual and text components, the identified topic and the identified target speaker, and generating a multimedia description of the multimedia event based on the identified target speaker, the identified topic, and the generated summary.
摘要翻译：本发明提供一种用于自动索引和检索多媒体内容的系统和方法。该方法可以包括将多媒体数据流分离成音频，视觉和文本组件，基于语义差异分割音频，视觉和文本组件，使用音频和视觉组件识别至少一个目标扬声器，识别多媒体事件的主题使用分段文本和主题类别模型，基于音频，视觉和文本组件，所识别的主题和所识别的目标扬声器生成多媒体事件的摘要，以及基于所识别的目标扬声器生成多媒体事件的多媒体描述，识别的主题和生成的摘要。

48. 发明授权

US07183262B2 Method for selective expression of therapeutic genes by hyperthermia 有权
公开(公告)号：US07183262B2
公开(公告)日：2007-02-27
申请号：US10172399
申请日：2002-06-14
申请人： Chuan-Yuan Li , Qian Huang , Mark W. Dewhirst
发明人： Chuan-Yuan Li , Qian Huang , Mark W. Dewhirst
IPC分类号： A01N43/04 , A01N63/00 , C12N15/00 , C12N15/63 , C07H21/04
CPC分类号： A61K38/191 , A61K38/208 , A61K48/00 , A61K48/0058 , C12N15/86 , C12N2710/10343 , C12N2830/002 , C12N2830/85 , C12N2840/203
摘要： A method for controlling in vivo heat-inducible gene expression for provision of therapeutic polypeptide. The method includes the steps of: (a) providing a construct comprising a polynucleotide encoding a therapeutic polypeptide, wherein the polynucleotide is operatively linked to a heat-inducible promoter; (b) administering the construct to a warm-blooded vertebrate at a site at or near the tumor; and (c) applying heat to the site at or near the tumor to express the therapeutic polypeptide, whereby anti-tumor activity is observed.

49. 发明授权

US06587586B1 Extracting textual information from a video sequence 失效
标题翻译：从视频序列中提取文本信息
公开(公告)号：US06587586B1
公开(公告)日：2003-07-01
申请号：US08999903
申请日：1997-06-12
申请人： Yuntao Cui , Qian Huang
发明人： Yuntao Cui , Qian Huang
IPC分类号： G06K934
CPC分类号： G06K9/325 , G06K9/6297 , G06K2209/15
摘要： A method for extracting an image representing textual information from a video sequence includes the following steps. First, receiving a sequence of video frames, each including an image of textual information. Then, locating the textual information in each frame of the video sequence to form a stack of text arrays, each array containing data representing substantially only the textual information. Finally, extracting a single textual image array representing the image of the textual information from the stack of text arrays. Apparatus for extracting an image representing textual information from a video sequence includes a source of a video sequence having a plurality of frames, each containing an image of the textual information; and a processor, coupled to the video sequence source, responsive to all of the plurality of frames, for generating a single array representing an image of the textual information.
摘要翻译：从视频序列提取表示文本信息的图像的方法包括以下步骤。首先，接收一系列视频帧，每个视频帧包括文本信息的图像。然后，将文本信息定位在视频序列的每个帧中以形成一组文本数组，每个数组包含基本上仅表示文本信息的数据。最后，从文本堆栈中提取表示文本信息图像的单个文本图像数组。用于从视频序列提取表示文本信息的图像的装置包括具有多个帧的视频序列的源，每个帧包含文本信息的图像; 以及处理器，耦合到所述视频序列源，响应于所述多个帧，用于生成表示所述文本信息的图像的单个阵列。

50. 发明授权

US06405166B1 Multimedia search apparatus and method for searching multimedia content using speaker detection by audio data 有权
标题翻译：多媒体搜索装置及使用音频数据的扬声器检测来搜索多媒体内容的方法
公开(公告)号：US06405166B1
公开(公告)日：2002-06-11
申请号：US09976023
申请日：2001-10-15
申请人： Qian Huang , Ivan Magrin-Chagnolleau , Sarangarajan Parthasarathy , Aaron Edward Rosenberg
发明人： Qian Huang , Ivan Magrin-Chagnolleau , Sarangarajan Parthasarathy , Aaron Edward Rosenberg
IPC分类号： G10L1700
CPC分类号： G10L17/00
摘要： A multimedia search apparatus and method for searching multimedia content using speaker detection to segment the multimedia content. The multimedia search apparatus receives a search request from a user device. The search request identifies the target speaker for which the search is to be conducted. Based on the search request, the multimedia search apparatus retrieves multimedia content from a multimedia database. The multimedia search apparatus retrieves models, such as Gaussian Mixture Models (GMMs), from a model storage device, corresponding to the target speaker and background data. Based on the retrieved models, the multimedia search device searches the multimedia data of the multimedia content and segments the multimedia data. The segments are identified by calculating an average normalized score for a block of frames of the multimedia data and determining if the average normalized score for the block of frames exceeds one or more predetermined thresholds.
摘要翻译：一种多媒体搜索装置和方法，用于使用说话者检测来搜索多媒体内容来分割多媒体内容。多媒体搜索装置从用户装置接收搜索请求。搜索请求标识要进行搜索的目标扬声器。基于搜索请求，多媒体搜索装置从多媒体数据库检索多媒体内容。多媒体搜索装置从对应于目标说话者和背景数据的模型存储装置中检索诸如高斯混合模型（GMM）的模型。基于所检索的模型，多媒体搜索装置搜索多媒体内容的多媒体数据并分割多媒体数据。通过计算多媒体数据的帧块的平均归一化分数并确定帧块的平均归一化分数是否超过一个或多个预定阈值来标识段。

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