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41. 发明专利

CA2198020A1 IRRADIATION CATHETER AND METHOD OF USE 未知
公开(公告)号：CA2198020A1
公开(公告)日：1996-03-07
申请号：CA2198020
申请日：1995-08-28
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61B17/00 , A61M25/00 , A61M25/10 , A61M36/04 , A61N5/10 , A61N5/00 , A61M29/00
摘要： This invention is a catheter (10) for use with a radioactive source (16) within the catheter (10) to irradiate a selected area of a blood vessel in combination with angioplasty procedures, to prevent restenosis of that area of the blood vessel. The catheter (10) has a guidewire channel (18) formed near its distal end to facilitate use of the catheter (10) as a rapid exchange catheter, allowing insertion of the catheter over a guidewire (20) also used in performance of an angioplasty procedure. The catheter (10) can also have a guidewire channel (19) formed near its proximal end to provide O-ring sealing surface and to facilitate free guidewire movement. The catheter (10) also has a closed end (13) to retain the radioactive source (16) within the catheter (10). The catheter (10) can be also be provided with a centering balloon (22) or a set of centering wire loops (50) to center the radioactive source (16) radially within the blood vessel.

42. 发明专利

DE69534522T2 未知
公开(公告)号：DE69534522T2
公开(公告)日：2006-07-06
申请号：DE69534522
申请日：1995-08-28
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61B17/00 , A61N5/10 , A61M25/00 , A61M25/10 , A61M36/04
摘要： This invention is a catheter (10) for use with a radioactive source (16) within the catheter (10) to irradiate a selected area of a blood vessel in combination with angioplasty procedures, to prevent restenosis of that area of the blood vessel. The catheter (10) has a guidewire channel (18) formed near its distal end to facilitate use of the catheter (10) as a rapid exchange catheter, allowing insertion of the catheter over a guidewire (20) also used in performance of an angioplasty procedure. The catheter (10) can also have a guidewire channel (19) formed near its proximal end to provide O-ring sealing surface and to facilitate free guidewire movement. The catheter (10) also has a closed end (13) to retain the radioactive source (16) within the catheter (10). The catheter (10) can be also be provided with a centering balloon (22) or a set of centering wire loops (50) to center the radioactive source (16) radially within the blood vessel.

43. 发明专利

DE69531406T2 未知
公开(公告)号：DE69531406T2
公开(公告)日：2004-10-07
申请号：DE69531406
申请日：1995-05-25
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61B17/00 , A61B17/12 , A61F2/06 , A61F2/84 , A61M25/00 , A61M29/02 , A61M39/00 , A61M29/00
摘要： A method and apparatus for blocking a body passageway by inserting an expandable frame into the passageway and expanding the frame with an expandable balloon to partially embed the frame in the walls of the passageway. The frame can carry a separate sealing membrane, or the balloon can function as the sealing membrane. The sealing membrane, the frame or the balloon can also carry a clot promoting substance. The balloon can be removed along with the inflation tube after the expansion procedure, if it is not serving as the sealing membrane, or the balloon can be detached from the inflation tube and left in place, either as a sealing membrane or simply to lock the frame in place. The frame can be maintained in its expanded state by being plastically deformed during the expansion step, or the frame can be maintained in its expanded state by having the balloon locked in the expanded state and left in place.

44. 发明专利

DE69530929T2 未知
公开(公告)号：DE69530929T2
公开(公告)日：2004-05-06
申请号：DE69530929
申请日：1995-08-28
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61B17/00 , A61M25/00 , A61M25/10 , A61M36/04 , A61N5/10 , A61M29/00 , A61N5/00
摘要： This invention is a catheter (10) for use with a radioactive source (16) within the catheter (10) to irradiate a selected area of a blood vessel in combination with angioplasty procedures, to prevent restenosis of that area of the blood vessel. The catheter (10) has a guidewire channel (18) formed near its distal end to facilitate use of the catheter (10) as a rapid exchange catheter, allowing insertion of the catheter over a guidewire (20) also used in performance of an angioplasty procedure. The catheter (10) can also have a guidewire channel (19) formed near its proximal end to provide O-ring sealing surface and to facilitate free guidewire movement. The catheter (10) also has a closed end (13) to retain the radioactive source (16) within the catheter (10). The catheter (10) can be also be provided with a centering balloon (22) or a set of centering wire loops (50) to center the radioactive source (16) radially within the blood vessel.

45. 发明专利

DE69124105D1 未知
公开(公告)号：DE69124105D1
公开(公告)日：1997-02-20
申请号：DE69124105
申请日：1991-10-30
申请人： BAXTER INT , HEIJER PETER DEN , TEIRSTEIN PAUL S
发明人： DEN HEIJER PETER , TEIRSTEIN PAUL , SIRIMANNE D , CUTTER SANDRA , KEMKEMIAN ZOHRAB
IPC分类号： A61M25/01

46. 发明专利

DE69938829D1 未知
公开(公告)号：DE69938829D1
公开(公告)日：2008-07-10
申请号：DE69938829
申请日：1999-06-02
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61N5/00 , A61M36/04 , A61N5/10

47. 发明专利

DE69531406D1 未知
公开(公告)号：DE69531406D1
公开(公告)日：2003-09-04
申请号：DE69531406
申请日：1995-05-25
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61B17/00 , A61B17/12 , A61F2/06 , A61F2/84 , A61M25/00 , A61M29/02 , A61M39/00 , A61M29/00
摘要： A method and apparatus for blocking a body passageway by inserting an expandable frame into the passageway and expanding the frame with an expandable balloon to partially embed the frame in the walls of the passageway. The frame can carry a separate sealing membrane, or the balloon can function as the sealing membrane. The sealing membrane, the frame or the balloon can also carry a clot promoting substance. The balloon can be removed along with the inflation tube after the expansion procedure, if it is not serving as the sealing membrane, or the balloon can be detached from the inflation tube and left in place, either as a sealing membrane or simply to lock the frame in place. The frame can be maintained in its expanded state by being plastically deformed during the expansion step, or the frame can be maintained in its expanded state by having the balloon locked in the expanded state and left in place.

48. 发明专利

CA2334198A1 IRRADIATION CATHETER WITH EXPANDABLE SOURCE 未知
公开(公告)号：CA2334198A1
公开(公告)日：1999-12-09
申请号：CA2334198
申请日：1999-06-02
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61M36/04 , A61N5/10 , A61N5/00
摘要： This patent is a radiation delivery system (10) having an expandable radiati on source (14) made of a pliable material. The source body is made of a materia l such as foam or sponge, or a fibrous material such as soft bristles of a pip e cleaner. The spongy or fibrous material is made radioactive by the implantation of a radioactive isotope. The radioactive isotope can be locate d throughout the pliable source material (14), or concentrated in a desired region, such as the surface or near-surface region (32). The compressible radioactive source material (14), when constrained by a constraining housing (38) or catheter (38), has a very low profile. When the constraining housing (38) or catheter (38) is withdrawn, the expandable source material (14) expands, and the expandable source material (14) is brought into direct contact with a vessel wall.

49. 发明专利

DE69219883D1 未知
公开(公告)号：DE69219883D1
公开(公告)日：1997-06-26
申请号：DE69219883
申请日：1992-02-27
申请人： BAXTER INT , TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL , NITA HENRY , DHUWALIA JAGDISH , EVANS SCOTT
IPC分类号： A61M25/01 , A61M29/02
摘要： A method and device for removing a first guide catheter and replacing the first guide catheter with a second guide catheter, without disturbing the placement of a flexible guide wire which has previously been inserted through the first guide catheter. The device of the invention comprises an "exchange catheter" which may be advanced over the outer surface of the pre-positioned guide wire to provide support and shielding of the guide wire during the catheter exchange procedure. A guide wire exit aperture formed in the "exchange catheter" permits the guide wire to exit the exchange catheter at a location whereby the operator may hold and manipulate the guide wire to maintain its desired position during the catheter exchange procedure.

50. 发明专利

CA2204501A1 RADIOGRAPHIC DYE DELIVERY APPARATUS AND METHOD 未知
公开(公告)号：CA2204501A1
公开(公告)日：1996-05-17
申请号：CA2204501
申请日：1995-11-07
申请人： TEIRSTEIN PAUL S
发明人： TEIRSTEIN PAUL S
IPC分类号： A61M1/00 , A61M5/178
摘要： A method and apparatus for injecting radiographic dye during angiography, are provided. A deformable holding chamber (14) is interposed between a contrast dye bottle (12) and a syringe manifold (16). A one-way valve (36) and an integral disconnect/flow stop (28) are connected between the bottle (12) and the holding chamber (14). A vent (54) is provided in the holding chamber (14), with a second one-way valve (58). Squeezing and releasing the deformable chamber (14) fills the chamber (14) from the bottle (12). The holding chamber (14) contains a floating baffle (52) which acts as a shutoff valve by plugging the chamber outlet if the chamber (14) becomes empty. The syringe (50) is used to withdraw dye from the holding chamber (14). If dye remains in the bottle (12) after performance of the procedure, the disconnect/flow stop fitting (28) can be disconnected, and the dye can be saved.

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