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41. 发明授权

US07121143B2 Optical pressure monitoring system 有权
公开(公告)号：US07121143B2
公开(公告)日：2006-10-17
申请号：US11103806
申请日：2005-04-11
申请人： James A. Malmstrom , Kent F. Beck , Scott D. Miles
发明人： James A. Malmstrom , Kent F. Beck , Scott D. Miles
IPC分类号： G01L9/00
CPC分类号： A61M5/16854 , A61M5/14232 , A61M2202/0482 , A61M2205/3306 , A61M2205/3351 , A61M2205/3355 , G01L9/0007
摘要： An optical pressure monitoring system includes a tube from an infusion set and an optical signal sensor disposed to detect changes in the diameter of the tube and thereby determine pressure changes within the tube. By selecting the position of the tube relative to the optical signal emitter and optical signal receiver, the optical signal sensor can both detect pressure changes and provide an integrity check for both the functioning of the optical signal sensor and the placement of the tube. By modifying the tube to exaggerate changes in tube diameter responsive to pressure changes, the sensitivity of the optical signal sensor can be increased.

42. 外观设计

USD507647S1 Enteral feeding pump cassette 失效
标题翻译：肠内给药盒
公开(公告)号：USD507647S1
公开(公告)日：2005-07-19
申请号：US29183387
申请日：2003-06-11
申请人： Kent F. Beck , Scott D. Miles
设计人： Kent F. Beck , Scott D. Miles

43. 外观设计

USD504506S1 Feeding pump cartridge 失效
标题翻译：进料泵墨盒
公开(公告)号：USD504506S1
公开(公告)日：2005-04-26
申请号：US29163153
申请日：2002-06-28
申请人： Kent F. Beck , Scott D. Miles
设计人： Kent F. Beck , Scott D. Miles

44. 发明授权

US06531708B1 Optical bubble detection system 有权
标题翻译：光学气泡检测系统
公开(公告)号：US06531708B1
公开(公告)日：2003-03-11
申请号：US09836840
申请日：2001-04-16
申请人： James A. Malmstrom , Kent F. Beck , Scott D. Miles
发明人： James A. Malmstrom , Kent F. Beck , Scott D. Miles
IPC分类号： G01N1506
CPC分类号： A61M5/365 , A61M5/14232 , A61M2205/12
摘要： An optical sensor includes a sample cell through which a fluid flows, an optical sensor formed by an optical emitter and an optical detector. The sample cell and the optical sensor use light refraction to determine the presence and size of a bubble passing through the sample cell. A housing may also be included to provide better control over light refraction and to protect the optical sensor.
摘要翻译：光学传感器包括流体流过的样品池，由光发射器形成的光学传感器和光学检测器。样品池和光学传感器使用光折射来确定通过样品池的气泡的存在和尺寸。还可以包括壳体以提供对光折射的更好控制并保护光学传感器。

45. 发明授权

US06523414B1 Optical pressure monitoring system 有权
标题翻译：光压监测系统
公开(公告)号：US06523414B1
公开(公告)日：2003-02-25
申请号：US09836852
申请日：2001-04-16
申请人： James A. Malmstrom , Kent F. Beck , Scott D. Miles
发明人： James A. Malmstrom , Kent F. Beck , Scott D. Miles
IPC分类号： G01L900
CPC分类号： A61M5/16854 , A61M5/14232 , A61M2202/0482 , A61M2205/3306 , A61M2205/3351 , A61M2205/3355 , G01L9/0007
摘要： An optical pressure monitoring system includes a tube from an infusion set and an optical signal sensor disposed to detect changes in the diameter of the tube and thereby determine pressure changes within the tube. By selecting the position of the tube relative to the optical signal emitter and optical signal receiver, the optical signal sensor can both detect pressure changes and provide an integrity check for both the functioning of the optical signal sensor and the placement of the tube. By modifying the tube to exaggerate changes in tube diameter responsive to pressure changes, the sensitivity of the optical signal sensor can be increased.
摘要翻译：光学压力监测系统包括来自输液器的管和设置成检测管的直径变化并由此确定管内的压力变化的光信号传感器。通过选择管相对于光信号发射器和光信号接收器的位置，光信号传感器既可以检测压力变化，又可以对光信号传感器的功能和放置管进行完整性检查。通过改变管以根据压力变化夸大管直径的变化，可以增加光信号传感器的灵敏度。

46. 发明授权

US5135304A Gas analysis system having buffer gas inputs to protect associated optical elements 失效
标题翻译：气体分析系统具有缓冲气体输入以保护相关的光学元件
公开(公告)号：US5135304A
公开(公告)日：1992-08-04
申请号：US771625
申请日：1991-10-04
申请人： Scott D. Miles , John R. Mitchell , Donald E. Gregonis , Joel M. Harris
发明人： Scott D. Miles , John R. Mitchell , Donald E. Gregonis , Joel M. Harris
IPC分类号： G01J3/44 , G01N21/15 , G01N21/39 , G01N21/65 , G01N21/85
CPC分类号： G01N21/15 , G01N21/65 , G01N2021/151 , G01N2021/391 , G01N2021/651 , G01N2021/8578
摘要： A gas analysis cell positioned within an optical resonant cavity in a gas analysis system is disclosed wherein the cell includes a flow of buffer gas which forms a "dam", thereby protecting the optical elements in the analysis system. The analysis cell includes an inlet for introducing a gas sample into the analysis chamber of the cell. Two buffer gas inlet ports, one on each end of the cell, are provided to introduce a flow of buffer gas which is directed past optical elements in the system adjacent the ends of the cell. Two output ports are located at the ends of the analysis chamber to remove the buffer gas and gas sample mixture. The flow of buffer gas acts to confirm the gas sample within the analysis chamber and reduce adverse effects which occur when the gas sample comes in contact with the optical elements of the system. By providing a constant non-turbulent flow of gas adjacent the system optics, adverse changes in index of refraction are avoided, thus reducing beam steering and Schlieren effects which can occur when Brewster windows or other optics are used to constrain the gas sample within the analysis cell. The buffer gas flow in the analysis cell of the present invention eliminates the need for gas cell windows which have intrinsic losses. This in turn minimizes losses which cause lower circulating intracavity power and signal strength.
摘要翻译：公开了一种位于气体分析系统中的光学谐振腔内的气体分析单元，其中所述单元包括形成“大坝”的缓冲气体流，从而保护分析系统中的光学元件。分析单元包括用于将气体样品引入电池的分析室的入口。提供两个缓冲气体入口端口，每个单元的每一端一个，以引入缓冲气体流，该缓冲气体流经过靠近电池端部的系统中的光学元件。两个输出端口位于分析室的端部，以去除缓冲气体和气体样品混合物。缓冲气体的流动用于确认分析室内的气体样品，并减少当气体样品与系统的光学元件接触时发生的不利影响。通过在系统光学器件附近提供恒定的非湍流气体，避免了折射率的不利变化，因此当使用布鲁斯特窗口或其他光学器件来限制分析中的气体样品时，可以发生波束转向和Schlieren效应细胞。本发明的分析池中的缓冲气体流动消除了对具有固有损失的气室的需求。这又减少了导致循环腔内功率和信号强度降低的损失。

47. 发明授权

US09693780B2 Medical device for modification of left atrial appendage and related systems and methods 有权
公开(公告)号：US09693780B2
公开(公告)日：2017-07-04
申请号：US12818059
申请日：2010-06-17
申请人： Scott D. Miles , Clark C. Davis , Daryl R. Edmiston , Richard J. Linder
发明人： Scott D. Miles , Clark C. Davis , Daryl R. Edmiston , Richard J. Linder
IPC分类号： A61M29/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/12122 , A61B17/0057 , A61B17/12022 , A61B17/12172 , A61B17/12177 , A61B2017/00309 , A61B2017/00327 , A61B2017/00575 , A61B2017/0069 , A61B2017/12054
摘要： Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a system for use in occluding an opening in the tissue of a body includes a handle, a catheter coupled with the handle and a medical device disposed within a lumen of the catheter. The medical device includes an anchor system having a plurality of anchor segments coupled with an anchor hub. The medical device further includes an occluder system having a plurality of occluder segments coupled with an occluder hub. A first actuator is configured to displace the occluder hub independent of, and relative to, the anchor hub to deploy the occluder system from a refracted state to an expanded state while the anchor system remains in a retracted state.

48. 发明授权

US09220487B2 Devices for reducing the size of an internal tissue opening 有权
标题翻译：用于减小内部组织开口尺寸的装置
公开(公告)号：US09220487B2
公开(公告)日：2015-12-29
申请号：US11836016
申请日：2007-08-08
申请人： Clark C. Davis , Scott D. Miles , DeWayne C. Fox , Daryl R. Edmiston , Richard J. Linder
发明人： Clark C. Davis , Scott D. Miles , DeWayne C. Fox , Daryl R. Edmiston , Richard J. Linder
IPC分类号： A61B17/00 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/0487 , A61B17/083 , A61B17/12122 , A61B17/12168 , A61B17/12172 , A61B2017/00084 , A61B2017/00407 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00606 , A61B2017/0061 , A61B2017/00619 , A61B2017/00623 , A61B2017/00654 , A61B2017/00858 , A61B2017/00862 , A61B2017/00867 , A61B2017/00884 , A61B2017/0488 , A61B2017/0496 , A61B2017/12054
摘要： A medical system for treating an internal tissue opening can include a closure device and associated delivery device. The closure device can include a body portion operatively associated with a first anchor and a second anchor. The body portion can include a plurality of segments defining a multi-cellular structure. A segment can define a variable width along a length of the segment to have a substantially equal stress level along the length when deflected. The closure device can be configured to apply lateral force to tissue of the internal tissue opening to bring tissue together for closure. The closure device can have a substantially flat aspect, and have a depth thickness that is substantially greater than the thickness or width of a majority of the members forming the closure device. The closure device can also include a member adapted to induce tissue growth.
摘要翻译：用于治疗内部组织开口的医疗系统可以包括闭合装置和相关联的递送装置。闭合装置可以包括与第一锚固件和第二锚固件可操作地相关联的主体部分。身体部分可以包括限定多细胞结构的多个片段。段可以沿着段的长度限定可变宽度，以在偏转时沿着长度具有基本相等的应力水平。闭合装置可以构造成向内部组织开口的组织施加横向力以将组织组合在一起以关闭。闭合装置可以具有基本平坦的方面，并且具有基本上大于形成封闭装置的构件的大部分的厚度或宽度的深度厚度。闭合装置还可以包括适于诱导组织生长的构件。

49. 发明授权

US09138208B2 Devices for reducing the size of an internal tissue opening 有权
标题翻译：用于减小内部组织开口尺寸的装置
公开(公告)号：US09138208B2
公开(公告)日：2015-09-22
申请号：US11836000
申请日：2007-08-08
申请人： Richard J. Linder , Clark C. Davis , Scott D. Miles , DeWayne C. Fox , Daryl R. Edmiston
发明人： Richard J. Linder , Clark C. Davis , Scott D. Miles , DeWayne C. Fox , Daryl R. Edmiston
IPC分类号： A61B17/03 , A61B17/00 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/0487 , A61B17/083 , A61B17/12122 , A61B17/12168 , A61B17/12172 , A61B2017/00084 , A61B2017/00407 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00606 , A61B2017/0061 , A61B2017/00619 , A61B2017/00623 , A61B2017/00654 , A61B2017/00858 , A61B2017/00862 , A61B2017/00867 , A61B2017/00884 , A61B2017/0488 , A61B2017/0496 , A61B2017/12054
摘要： A medical system for treating an internal tissue opening can include a closure device and associated delivery device. The closure device can include a body portion operatively associated with a first anchor and a second anchor. The body portion can include a plurality of segments defining a multi-cellular structure. The closure device can be configured to apply lateral force to tissue of the internal tissue opening to bring tissue together. The closure device can have a substantially flat aspect, and have a depth thickness that is substantially greater than the thickness or width of a majority of the members forming the closure device to reduce out of plane bending. The closure device can also include a member adapted to induce tissue growth.
摘要翻译：用于治疗内部组织开口的医疗系统可以包括闭合装置和相关联的递送装置。闭合装置可以包括与第一锚固件和第二锚固件可操作地相关联的主体部分。身体部分可以包括限定多细胞结构的多个片段。闭合装置可以构造成向内部组织开口的组织施加横向力以将组织带到一起。闭合装置可以具有基本平坦的方面，并且具有基本上大于形成闭合装置的构件的大部分的厚度或宽度的深度厚度，以减少平面外的弯曲。闭合装置还可以包括适于诱导组织生长的构件。

50. 发明授权

US08845711B2 Medical device for modification of left atrial appendage and related systems and methods 有权
标题翻译：用于修改左心耳和相关系统和方法的医疗装置
公开(公告)号：US08845711B2
公开(公告)日：2014-09-30
申请号：US12253831
申请日：2008-10-17
申请人： Scott D. Miles , Richard J. Linder , Clark C. Davis , Brian K. Whisenant , Daryl R. Edmiston , DeWayne C. Fox
发明人： Scott D. Miles , Richard J. Linder , Clark C. Davis , Brian K. Whisenant , Daryl R. Edmiston , DeWayne C. Fox
IPC分类号： A61F2/06 , A61B17/00 , A61B17/12 , A61B17/064 , A61B17/04
CPC分类号： A61B17/12122 , A61B17/00491 , A61B17/12022 , A61B17/1214 , A61B17/1215 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B2017/00243 , A61B2017/00898 , A61B2017/0412 , A61B2017/0427 , A61B2017/0649 , A61B2017/1205
摘要： Several embodiments are set forth of devices, systems and methods for modifying an atrial appendage such as a left atrial appendage (LAA). In one embodiment, a device includes a body that is collapsible and self-expanding. The body includes a textured surface with protruding portions and recessed portions. The body may be formed of a reticulated foam material and may exhibit a substantially spherical geometry or a truncated spherical geometry. The body may be substantially hollow. In one embodiment, portions of the textured surface may be metalized or have a coating placed thereon to enhance frictional engagement of the body with the atrial appendage wall. In another embodiment, a mesh bag is disposed within an LAA and one or more self-expanding bodies are disposed within the mesh bag. The mesh bag is then secured to retain the self-expanding bodies within the bag and the LAA.
摘要翻译：阐述用于修改诸如左心耳（LAA）的心房附件的装置，系统和方法的几个实施例。在一个实施例中，装置包括可折叠和自展开的主体。主体包括具有突出部分和凹陷部分的纹理表面。主体可以由网状泡沫材料形成，并且可以呈现基本上球形的几何形状或截顶的球形几何形状。身体可以是基本上中空的。在一个实施例中，纹理表面的部分可以被金属化或者具有放置在其上的涂层，以增强身体与心耳壁的摩擦接合。在另一个实施例中，网袋设置在LAA内，并且一个或多个自膨胀体设置在网袋内。然后固定网袋以将自膨胀体保持在袋和LAA内。

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