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41. 发明申请

WO2008091935A2 ORAL CARE IMPLEMENT HAVING FLUID DELIVERY SYSTEM 审中-公开
标题翻译：具有流体输送系统的口腔护理实施
公开(公告)号：WO2008091935A2
公开(公告)日：2008-07-31
申请号：PCT/US2008/051778
申请日：2008-01-23
申请人： COLGATE-PALMOLIVE COMPANY , GATZEMEYER, John, J. , BOYD, Thomas, J. , JIMENEZ, Eduardo, J. , RUSSELL, Bruce, M.
发明人： GATZEMEYER, John, J. , BOYD, Thomas, J. , JIMENEZ, Eduardo, J. , RUSSELL, Bruce, M.
IPC分类号： A46B11/00
CPC分类号： A46B11/002 , A46B9/04 , A46B11/001 , A46B11/0082 , A46B13/023 , A46B15/0002 , A46B15/0032 , A46B15/0055 , A46B15/0075 , A46B15/0081 , A46B2200/1066 , A61C17/227
摘要： An oral care implement has a head portion with tooth cleaning elements on one surface thereof and a reservoir containing at least one active agent. A capillary channel extends through at least a portion of the oral care implement to deliver active agent(s) to one or more outlets. In one aspect, a vibration-producing device is provided to vibrate at least a portion of the implement to enhance the function of tooth cleaning elements and the delivery of the active agent through capillary action. A variety of active agents can be administered for therapeutic, hygienic, and/or other benefits, such as fresh breath, tooth whitening, or producing sensations of heat, cool, or tingling.
摘要翻译：口腔护理器具具有在其一个表面上具有牙齿清洁元件的头部和包含至少一种活性剂的贮存器。毛细通道延伸穿过口腔护理器具的至少一部分，以将活性剂递送到一个或多个出口。在一个方面，提供振动产生装置以振动器具的至少一部分，以增强牙齿清洁元件的功能和通过毛细管作用递送活性剂。可以施用各种活性剂用于治疗，卫生和/或其他益处，例如新鲜呼吸，牙齿美白或产生热，凉或刺痛的感觉。

42. 发明申请

WO2007022167A1 INHIBITION OF BACTERIAL DEPOSITION ON ORAL SURFACES 审中-公开
标题翻译：在口腔表面抑制细菌沉积
公开(公告)号：WO2007022167A1
公开(公告)日：2007-02-22
申请号：PCT/US2006/031803
申请日：2006-08-16
申请人： COLGATE-PALMOLIVE COMPANY , GAFFAR, Abdul , BOYD, Thomas, J.
发明人： GAFFAR, Abdul , BOYD, Thomas, J.
IPC分类号： A61K8/896 , A61Q11/00
CPC分类号： A61K8/44 , A61K8/81 , A61Q11/00
摘要： The invention is directed to an oral composition that contains an amphoteric surfactant and an homo- or copolymer comprising an ethylenic monomer and related methods. The ethylenic monomer includes a phosphonate group. The monomer may be represented by the structure of Formula (I), wherein one of A and A' is a hydrogen atom and the other is selected from a hydrogen atom or a group -(X) n R m ; wherein n is i\selected from 0 or 1; provided that when n is 0, m is 1, and when n is 1, m is an integer of 1 to 3; X is selected from an oxygen atom, a sulfur atom, a nitrogen atom, a phosphorous atom, and silicon atom; R is independently a hyuderogen atom or an arganic radical; L is selected from a bond and a linking group; M and M' are independently selected from a hydrogen atom, an alkali metal, and an ammonium ion, or together form an alkaline earth metal or other divalent element; and p is 1 or 2, provided that when L is a bond, p is 1.
摘要翻译：本发明涉及含有两性表面活性剂和包含烯属单体的均聚物或共聚物和相关方法的口腔组合物。烯属单体包括膦酸酯基团。单体可以由式（I）的结构表示，其中A和A'中的一个是氢原子，另一个选自氢原子或基团 - （X）n R _{米; 其中n是从0或1中选择的; 条件是当n为0时，m为1，当n为1时，m为1〜3的整数。 X选自氧原子，硫原子，氮原子，磷原子和硅原子; R独立地是杂原子原子或有机基团; L选自键和连接基; M和M'独立地选自氢原子，碱金属和铵离子，或一起形成碱土金属或其它二价元素; p为1或2，条件是当L为键时，p为1。}

43. 发明申请

WO2006127898A3 (S)-N-METHYLNALTREXONE, PROCESS FOR ITS SYNTHESIS AND ITS PHARMACEUTICAL USE 审中-公开
标题翻译：（S）-N-甲基四氢呋喃，其合成方法及其药物用途
公开(公告)号：WO2006127898A3
公开(公告)日：2007-02-08
申请号：PCT/US2006020232
申请日：2006-05-25
申请人： PROGENICS PHARM INC , WAGONER HOWARD , SANGHVI SUKETU P , BOYD THOMAS A , VERBICKY CHRISTOPHER , ANDRUSKI STEPHEN
发明人： WAGONER HOWARD , SANGHVI SUKETU P , BOYD THOMAS A , VERBICKY CHRISTOPHER , ANDRUSKI STEPHEN
IPC分类号： C07D489/08 , A61K31/485 , A61P1/12 , A61P25/04
CPC分类号： C07D489/08
摘要： This invention relates to S-MNTX, methods of producing S-MNTX, pharmaceutical preparations comprising S-MNTX and methods for their use.
摘要翻译：本发明涉及S-MNTX，S-MNTX的制备方法，包含S-MNTX的药物制剂及其使用方法。

44. 发明申请

WO2007013937A1 ORAL COMPOSITION CONTAINING NON-AGGREGATED ZINC NANOPARTICLES 审中-公开
标题翻译：含有非聚集锌纳米颗粒的口腔组合物
公开(公告)号：WO2007013937A1
公开(公告)日：2007-02-01
申请号：PCT/US2006/028090
申请日：2006-07-20
申请人： COLGATE-PALMOLIVE COMPANY , BOYD, Thomas, J. , XU, Guofeng , VISCIO, David , GAFFAR, Abdul , ARVANITIDOU, Evangelia , FRUGE, Linh
发明人： BOYD, Thomas, J. , XU, Guofeng , VISCIO, David , GAFFAR, Abdul , ARVANITIDOU, Evangelia , FRUGE, Linh
IPC分类号： A61K8/27 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/27 , A61K2800/413 , B82Y5/00
摘要： An oral composition comprising a vehicle and a zinc ion source in the form of nanoparticles that are substantially non-aggregated and methods for use of such compositions are described. The composition provides antiplaque and anti malodor benefits to the user and the inclusion of nanoparticles permits a reduction in the amount of zinc ions present in the composition while maintaining efficacy.
摘要翻译：描述了包含基本上不聚集的纳米颗粒形式的载体和锌离子源的口腔组合物以及使用这种组合物的方法。组合物为使用者提供抗斑和抗恶臭益处，并且包含纳米颗粒允许在保持功效的同时减少组合物中存在的锌离子的量。

45. 发明申请

WO2006127898A2 (S)-N-METHYLNALTREXONE 审中-公开
标题翻译：（S） - N - 甲
公开(公告)号：WO2006127898A2
公开(公告)日：2006-11-30
申请号：PCT/US2006/020232
申请日：2006-05-25
申请人： PROGENICS PHARMACEUTICALS, INC. , WAGONER, Howard , SANGHVI, Suketu, P. , BOYD, Thomas, A. , VERBICKY, Christopher , ANDRUSKI, Stephen
发明人： WAGONER, Howard , SANGHVI, Suketu, P. , BOYD, Thomas, A. , VERBICKY, Christopher , ANDRUSKI, Stephen
IPC分类号： C07D489/08 , A61K31/485 , A61P1/12 , A61P25/04
CPC分类号： C07D489/08
摘要： This invention relates to S-MNTX, methods of producing S-MNTX, pharmaceutical preparations comprising S-MNTX and methods for their use.
摘要翻译：本发明涉及S-MNTX，S-MNTX的制备方法，包含S-MNTX的药物制剂及其使用方法。

46. 发明申请

WO2006069210A2 ORAL CARE COMPOSITIONS CONTAINING FLAVONOIDS AND FLAVANS 审中-公开
标题翻译：含有FLAVONOIDS和FLAVANS的口腔护理组合物
公开(公告)号：WO2006069210A2
公开(公告)日：2006-06-29
申请号：PCT/US2005046522
申请日：2005-12-21
申请人： COLGATE PALMOLIVE CO , XU GUOFENG , BOYD THOMAS J , HAO ZHIGANG , VISCIO DAVID , GAFFAR ABDUL , MELLO SARITA V , ARVANITIDOU EVANGELIA S , PRENCIPE MICHAEL
发明人： XU GUOFENG , BOYD THOMAS J , HAO ZHIGANG , VISCIO DAVID , GAFFAR ABDUL , MELLO SARITA V , ARVANITIDOU EVANGELIA S , PRENCIPE MICHAEL
IPC分类号： A61Q11/02 , A61K8/19 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/49 , A61K8/81 , A61P29/00 , A61Q11/00
CPC分类号： A61K8/347 , A61K8/345 , A61K8/498 , A61K8/8164 , A61Q11/00
摘要： Oral care compositions containing: a free-B-ring flavonoid and a flavan; as well as at least one bioavailability-enhancing agent are provided. Methods of using the oral compositions are also provided.
摘要翻译：口服护理组合物，含有：B型环形黄酮和黄烷; 以及至少一种生物利用度增加剂。还提供了使用口腔组合物的方法。

47. 发明申请

WO2005117821A1 ANTI-STAINING ANTIBACTERIAL DENTIFRICE 审中-公开
标题翻译：抗生素抗菌素
公开(公告)号：WO2005117821A1
公开(公告)日：2005-12-15
申请号：PCT/US2005/019415
申请日：2005-06-02
申请人： COLGATE-PALMOLIVE COMPANY , MILANOVICH, Nebojsa , GAFFAR, Abdul , PRENCIPE, Michael , BOYD, Thomas
发明人： MILANOVICH, Nebojsa , GAFFAR, Abdul , PRENCIPE, Michael , BOYD, Thomas
IPC分类号： A61K7/16
CPC分类号： A61K8/33 , A61K8/81 , A61K8/8164 , A61K2800/52 , A61Q11/00
摘要： An anti-staining, antibacterial dentifrice comprises an anti-staining effective amount of an orally acceptable polymer or copolymer that comprises a plurality of monomeric groups of formula (I) wherein (a) one of A and A' is hydrogen and the other is a moiety (X) n (R) m , (b) n in individual such moieties is independently 0 or 1, (c) linking groups X if present independently comprise an oxygen, sulfur, nitrogen, phosphorus or silicon atom, (d) where n is 0, m is 1, and where n is 1, m is independently an integer from 1 to 3 as determined by X, (e) terminal groups R are independently hydrogen or C 1-18 organic radicals, and (f) M and M' are independently selected from hydrogen, alkali metal and ammonium; said polymer or copolymer having an average molecular weight of at least about 1,000. The dentifrice further comprises an antibacterial effective amount of an orally acceptable halogenated diphenylether antibacterial agent, and an antibacterial enhancing effective amount of an orally acceptable polyvinylmethylether/maleic anhydride copolymer.
摘要翻译：抗污染的抗菌洁齿剂包括抗染色有效量的口服可接受的聚合物或共聚物，其包含多个式（I）的单体基团，其中（a）A和A'之一是氢，另一个是单独这样的部分中的部分（X）n（R）m，（b）n独立地为0或1，（c）连接基团X（如果存在）独立地包含氧，硫，氮，磷或硅原子，（d） n为0，m为1，n为1时，m独立地为1〜3的整数，由X确定，（e）端基R独立地为氢或C 1-18有机基团，（f）M和 M'独立地选自氢，碱金属和铵; 所述聚合物或共聚物的平均分子量至少约为1,000。洁齿剂还包含抗菌有效量的口服可接受的卤化二苯醚抗菌剂，以及抗菌增强有效量的口服可接受的聚乙烯基甲基醚/马来酸酐共聚物。

48. 发明申请

WO2005000255A3 ANTIPLAQUE CONFECTIONERY DENTAL COMPOSITION 审中-公开
公开(公告)号：WO2005000255A3
公开(公告)日：2005-01-06
申请号：PCT/US2004/020035
申请日：2004-06-23
申请人： COLGATE-PALMOLIVE COMPANY , BOYD, Thomas, J. , XU, Guofeng , GAFFAR, Abdul , VISCIO, David, B.
发明人： BOYD, Thomas, J. , XU, Guofeng , GAFFAR, Abdul , VISCIO, David, B.
IPC分类号： A61K7/16
摘要： A confectionery composition delivering antiplaque agents to the oral cavity when applied thereto, the composition being comprised of a homogeneous mixture of a solid base material and an antibacterial ester having the formula (I); wherein R is an alkyl chain of 1 to 8 carbon atoms and R 1 is an alkyl chain of 6 to 30 carbon atoms and X is an anion.

49. 发明申请

WO2005000254A2 ANTIPLAQUE BREATH FRESHENING CONSUMABLE FILM 审中-公开
标题翻译：防静电消毒消毒片
公开(公告)号：WO2005000254A2
公开(公告)日：2005-01-06
申请号：PCT/US2004020034
申请日：2004-06-23
申请人： COLGATE PALMOLIVE CO , BOYD THOMAS J , XU GUOFENG , GAFFAR ABDUL , VISCIO DAVID B
发明人： BOYD THOMAS J , XU GUOFENG , GAFFAR ABDUL , VISCIO DAVID B
IPC分类号： A61K8/44 , A61Q11/00 , A61K7/00
CPC分类号： A61Q11/00 , A61K8/44
摘要： An orally consumable film composition for delivering antiplaque and breath freshening benefits to the oral cavity which is rapidly dissolvable or dispersible in the oral cavity, the composition being comprised of a homogeneous mixture of a water soluble or dispersible film forming polymer and an antibacterial ester having the formula (I), where R is an alkyl chain of 1 to 8 carbon atoms, and R is an alkyl chain of 6 to 30 carbon atoms and X is an anion.
摘要翻译：一种口腔消耗性薄膜组合物，其用于将口腔和呼吸清新的益处输送到口腔中，其可快速溶解或分散在口腔中，该组合物由水溶性或分散性成膜聚合物和抗菌酯的均匀混合物组成，其具有式（I），其中R 1是1至8个碳原子的烷基链，R 2是6至30个碳原子的烷基链，X是阴离子。

50. 发明申请

WO2004082916A2 ROTARY INJECTION MOLDING APPARATUS AND METHOD FOR USE CROSS-REFERENCE TO RELATED APPLICATIONS 审中-公开
标题翻译：旋转注射成型装置及其使用方法相关申请的交叉引用
公开(公告)号：WO2004082916A2
公开(公告)日：2004-09-30
申请号：PCT/US2004/008326
申请日：2004-03-17
申请人： MANUFACTURING TECHNOLOGIES INTERNATIONAL CORPORATION , BOYD, Kathy , BOYD, Thomas, J.
发明人： BOYD, Kathy , BOYD, Thomas, J.
IPC分类号： B29C
CPC分类号： B29C45/06 , B29C45/14008 , B29C45/42 , B29C45/54 , B29C2045/425 , B29K2021/00
摘要： A rotary injection molding apparatus [10] and method for manufacturing products containing elastomeric material within multi-section single cavity molds [30]. The apparatus includes a modular frame [20] supporting an injection molding operation station [40] having an injector assembly [48] with a pressure sensitive nozzle assembly [50, 51]. The injector assembly [48] is engaged with an extruder assembly [46] at a check valve assembly [44]. A mold servicer assembly [42] is provided for assembly and disassembly of multi-section single cavity molds. A robotic arm assembly [70] is supported on the modular frame and positioned for inserting and removing products or product components from disassembled molds. Finally; a rotating table [22] is provided on the frame which has a plurality of work station positions [24] supporting clamping assemblies [28] for clamping single cavity molds [30] around the periphery of the rotating table [22].
摘要翻译：一种旋转注射成型装置[10]，以及在多段单腔模具中制造含有弹性体材料的产品的方法[30]。该装置包括支撑具有压敏喷嘴组件[50,51]的注射器组件[48]的注射成型操作站[40]的模块化框架20。注射器组件[48]在止回阀组件[44]处与挤出机组件[46]接合。提供了一种模具维修组件[42]，用于组装和拆卸多段单腔模具。机械手臂组件[70]支撑在模块化框架上，并定位成用于从拆卸的模具中插入和移除产品或产品组件。最后; 在框架上设置有一个旋转台[22]，其具有多个工作站位置[24]，支撑夹紧组件[28]，用于围绕旋转工作台[22]的周边夹持单腔模具30。

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